ACE C18-AR and C18-PFP - Hplc.eu

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®ACEHPLC / UHPLC Columns16 Pharmaceutically Relevant Analytes – C18 Columns12ACE Excel 2 C18P max: 309 barWatersAcquity 1.7 BEH C18P max: 478 barPhenomenaKinetex 1.7 C18P max: 446 bar1, 2121Agilent ZorbaxEclipse 1.8 XBD C18P max: 396 bar 1 23, 4253334445 65 67675 6787898810910, 119101211109111213111612 13 14 1513 14 15 161614 1514 1512161350x2.1mmA: 20 mM KH 2 PO 4 , pH 2.7B: 20 mM KH 2 PO 4 , pH 2.7 inMeOH/H 2 O (65:35 v/v)Gradient: 3 – 100 %B in 5 minFlow rate: 0.6 ml/minTemperature: 60CDetection: 214 nm1. N‐Acetylprocainamide2. 3‐Hydroxybenzoic acid3. Pindolol4. Methylphenylsulfoxide5. Benzyl alcohol6. Quinoxaline7. 1,4‐Dinitrobenzene8. Phenacetin9. 1,2‐Dimethoxybenzene10. Furosemide11. Anisole12. Methyl benzoate13. Remacemide14. Nimesulide15. Ethyl benzoate16. Diflunisal1 2 3 4 5C18 phases show ‘similar’ selectivity...minAll trademarks are recognised...comparative separations may not be representative of all applications
®ACEHPLC / UHPLC ColumnsThe Challenge...13To engineer new phases with alternative selectivity butwith the robust properties of the C18 ligand− Reproducible (column-to-column & batch-to-batch)− Excellent column lifetime− Superb efficiency provided by ultra-inert, ultra-pure silica particle− Low MS bleed− Usable in 100% aqueous eluentsAvailable for HPLC & UHPLC separationsAvailable as a ‘Phase III Ready’ product familyGlobally available, supply chain, reproducible, multiple batches etc
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ACE C18-AR and C18-PFP - Hplc.eu

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