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Expertise in Synergy - Glatt

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Background<br />

More and more pharmaceutical products are reach<strong>in</strong>g<br />

the market as multiparticulate dosage forms,<br />

ma<strong>in</strong>ly as pellets. The healthcare sector also frequently<br />

selects pellets as an optimal marketable form<br />

of functional food. As there is quite a number of existent<br />

techniques relat<strong>in</strong>g to the production of pellets,<br />

it is often very difficult for a formulator or market<strong>in</strong>g<br />

manager to make a choice, s<strong>in</strong>ce every technique<br />

claims to be optimal.<br />

This workshop is aimed at elaborat<strong>in</strong>g the advantages<br />

and drawbacks of the <strong>in</strong>dividual techniques, focus<strong>in</strong>g<br />

on the optimal spectrum of each one, but also consider<strong>in</strong>g<br />

the economical and ergonomical aspects of<br />

manufactur<strong>in</strong>g processes. On special request of various<br />

participants, this workshop has been extended<br />

to <strong>in</strong>clude lectures on the ma<strong>in</strong> excipients for pelletiz<strong>in</strong>g<br />

and pellet coat<strong>in</strong>g, on functional pellet coat<strong>in</strong>g,<br />

compression of pellets <strong>in</strong>to tablets, capsule fill<strong>in</strong>g and<br />

the most suitable capsule materials. All speakers are<br />

specialized, experienced and renowned experts from<br />

science and <strong>in</strong>dustry.<br />

Speakers Topics<br />

Dr. Jörg Brunemann<br />

Syntapharm, Germany<br />

Dr. Dom<strong>in</strong>ique Cadé<br />

Pfizer, France<br />

Dr. Pascale Gauthier<br />

University of Clermont-Ferrand, France<br />

Michael Jacob<br />

<strong>Glatt</strong> Weimar, Germany<br />

Dr. Bruno Leclercq<br />

FMC, Belgiium<br />

Dr. Atul Mehta<br />

Mehta Consult<strong>in</strong>g, USA<br />

Prof. Dr. Mike Newton<br />

The London School of Pharmacy, UK<br />

Dr. Raphael Plüss<br />

Encap BioSystems Inc., Switzerland<br />

Dr. Norbert Pöll<strong>in</strong>ger<br />

<strong>Glatt</strong> Pharmaceutical Services, Germany<br />

Prof. Dr. Agba D. Salman<br />

Sheffield University, UK<br />

Dr. Thilo Schmierer<br />

Pfizer, France<br />

Dr. Karlhe<strong>in</strong>z Seyfang<br />

Harro Höfliger, Germany<br />

Dr. Anke Stroyer Bayer<br />

HealthCare AG, Germany<br />

t<br />

Workshop no. 146<br />

Multiparticle<br />

Dosage<br />

Form<br />

l Pellets as oral multiparticulate dosage forms<br />

l High Shear pelletiz<strong>in</strong>g<br />

l Cont<strong>in</strong>uous fluid bed pelletization<br />

l Preparation of pellets by extrusion / spheronization<br />

l Pelletiz<strong>in</strong>g by solution, suspension and dry powder layer<strong>in</strong>g<br />

l Rotor pelletization techniques<br />

l Innovative technologies for the development and production of<br />

controlled release pellets<br />

l Case study: Solid state <strong>in</strong>teractions between proton pump <strong>in</strong>hibitor<br />

omeprazole and enteric coat<strong>in</strong>g polymers<br />

l The ma<strong>in</strong> excipients for pelletiz<strong>in</strong>g and pellet coat<strong>in</strong>g<br />

l Functional filmcoat<strong>in</strong>g of pellets<br />

l Adjust<strong>in</strong>g desired drug release k<strong>in</strong>etics from ethylcellulose-coated pellets<br />

l Compatibility tests to perform with capsules<br />

l Capsule systems today and tomorrow<br />

l Capsule fill<strong>in</strong>g techniques<br />

l Excursion to Capsugel <strong>in</strong> Colmar (France) to look at <strong>in</strong>novative<br />

capsule technology<br />

l Pelletiz<strong>in</strong>g by prill<strong>in</strong>g: Theory and practise (demo)<br />

l Process demonstrations:<br />

direct pelletiz<strong>in</strong>g<br />

suspension layer<strong>in</strong>g<br />

capsule fill<strong>in</strong>g<br />

B<strong>in</strong>zen, 8 -10 September 2009<br />

To register www.ttc-b<strong>in</strong>zen.de<br />

International Times No. 27 · March 2009<br />

17

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