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Genzyme And <strong>Glatt</strong><br />
a w<strong>in</strong>n<strong>in</strong>g cooperation for a new state of the art pharmaceutical plant<br />
In 1959 just five years after hav<strong>in</strong>g established the company<br />
<strong>in</strong> B<strong>in</strong>zen, Werner <strong>Glatt</strong> together with just a dozen employees designed<br />
and constructed one of the world's first fluid bed plants,<br />
suitable for <strong>in</strong>dustrial application <strong>in</strong> the pharmaceutical <strong>in</strong>dustry.<br />
<strong>Glatt</strong>'s <strong>in</strong>ternational activity developed due to an ever <strong>in</strong>creas<strong>in</strong>g<br />
satisfied customer base and grow<strong>in</strong>g <strong>in</strong>ternational demand. In<br />
1971, <strong>Glatt</strong> AG was founded <strong>in</strong> Switzerland, followed by <strong>Glatt</strong> Air<br />
Techniques (GAT) <strong>in</strong> Ramsey, USA <strong>in</strong> 1973. <strong>Glatt</strong> AG was <strong>in</strong>strumental<br />
<strong>in</strong> launch<strong>in</strong>g a second product family onto the market: the<br />
<strong>Glatt</strong> Coater. Today, the <strong>Glatt</strong> Corporation is a truly global company<br />
group. It employs a workforce of over 1,300 at its various<br />
locations and works with over 50 permanent agencies who act as<br />
local po<strong>in</strong>ts of contact for customers around the world.<br />
People's ideas and expectations change the same as the economic<br />
climate. There is however one th<strong>in</strong>g that has not changed <strong>in</strong><br />
almost 50 years: Our focus on customer satisfaction.<br />
In 1989 Re<strong>in</strong>er Nowak took over as Chief Executive Officer from<br />
Werner <strong>Glatt</strong>, and made the most of the opportunities conceived<br />
by the new development tak<strong>in</strong>g place <strong>in</strong> Germany. <strong>Glatt</strong> has<br />
grown along with its customers over the past fifty years. Start<strong>in</strong>g<br />
from fluid beds, today we plan and supply complex systems specific<br />
to the entire spectrum of solid pharmaceutical production,<br />
exclusively us<strong>in</strong>g orig<strong>in</strong>al <strong>Glatt</strong> equipment, or <strong>in</strong> cooperation with<br />
reputable suppliers.<br />
Three <strong>Glatt</strong> locations are together operat<strong>in</strong>g to successfully f<strong>in</strong>alise<br />
the new Genzyme plant on time: <strong>Glatt</strong> GmbH <strong>in</strong> B<strong>in</strong>zen (Germany),<br />
Headquarters of the <strong>Glatt</strong> Group, with the important<br />
automation part for the new facility; <strong>Glatt</strong> AG <strong>in</strong> Pratteln (Switzerland)<br />
responsible for the tablet coater; and <strong>Glatt</strong> Systemtechnik<br />
GmbH <strong>in</strong> Dresden (Germany) responsible for the high shear<br />
mixer, the conta<strong>in</strong>ment technology and the complete product<br />
handl<strong>in</strong>g solutions. All three companies have established a s<strong>in</strong>gle<br />
project team, work<strong>in</strong>g together with PM Eng<strong>in</strong>eer<strong>in</strong>g and our<br />
By Ralf Kretzschmar, <strong>Glatt</strong> Dresden<br />
client Genzyme, to carry out the most efficient process solution <strong>in</strong><br />
time. Integrated systems are nowadays <strong>in</strong> great demand – preferably<br />
com<strong>in</strong>g from one source. With product handl<strong>in</strong>g, the ma<strong>in</strong><br />
criteria are primarily determ<strong>in</strong>ed by the type of product flow,<br />
degree of automation and level of conta<strong>in</strong>ment.<br />
Whether weigh<strong>in</strong>g, dos<strong>in</strong>g, blend<strong>in</strong>g, siev<strong>in</strong>g, stor<strong>in</strong>g, transport<strong>in</strong>g,<br />
dock<strong>in</strong>g or the necessary documentation, whether manually<br />
or automatically controlled – <strong>Glatt</strong> together with Genzyme has<br />
developed the optimum solution for the required application.<br />
Someth<strong>in</strong>g always starts with an idea, which then leads on to a<br />
concept. Special requirements are voiced, restrictions come <strong>in</strong>to<br />
play, specifications have to be complied with and decisions to be<br />
taken: the targeted production capacity, vertical or horizontal product<br />
flow, manual or automatic handl<strong>in</strong>g, and the degree of control<br />
<strong>in</strong>tegration. Open handl<strong>in</strong>g or total conta<strong>in</strong>ment. WIP or CIP.<br />
The safety concept...<br />
There are often various different solutions which have to be<br />
assessed. Structural circumstances on site and the type of products<br />
be<strong>in</strong>g produced have to be taken <strong>in</strong>to consideration.<br />
Project management is a key factor here. Interfaces and fields of<br />
10 International Times No. 27 · March 2009