Nevus Sebaceous, Epidermal Nevi, and Epidermal Nevus Syndrome

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Proteus Syndrome‣ NIH diagnostic criteria‣ Lipomas, Vascular malformations, Plantar cerebriformconn tiss nevi, Epid nevi, Lipohypoplasia, Dermalhypoplasia‣ PTEN association does not apply‣ 26/29 with AKT1 somatic mutation-oncogene encoding AKT1 kinase (cellproliferation/apoptosis (NEJM 2011;365:611)
CLOVE Syndrome‣ Congenital Lipomatous Overgrowth,Vascular Malformation, Epidermal Nevi‣ Proportionate overgrowth‣ Risk of central/thoracic phlebectasia andpulmonary embolism (PE)-12 pts with CLOVE; 11/12 with phlebect.-2/11 with perioperative PE; one deathJ Thor Cardiovasc Surg 2010;140:459
Page 1: Nevus Sebaceous, EpidermalNevi, and
Page 4 and 5: Nevus Sebaceous‣ Congenital… so
Page 6 and 7: Nevus Sebaceous -Malignancy‣ Some
Page 8 and 9: Nevus Sebaceous - Malignancy‣ 4,9
Page 10 and 11: Epidermal and Sebaceous Nevi‣ “
Page 12: Epidermal Nevus Syndrome‣ Epiderm
Page 15 and 16: Am J Med Genet 2005;139A:67
Page 17: Proteus Syndrome‣ Epidermal Nevus
Page 21 and 22: Epidermal Nevi -Management‣ None

Nevus Sebaceous, Epidermal Nevi, and Epidermal Nevus Syndrome

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