66 Chapter 4. <strong>Online</strong> <strong>CBT</strong> <strong>of</strong> Panic Symptomsanalyses showed that approximately 70 participants (35 per group) were needed todetect a large, d = .8, between-group effect (with ANCOVA, an estimated pre-postcorrelation <strong>of</strong> .5 <strong>and</strong> Holm-Bonferroni corrections for comparisons on 10 outcomemeasures).Screening. Respondents were screened through web-administered self-report questionnaires<strong>and</strong> a semi-structured 15-minute telephonic interview. Participants firstcompleted the self-report questionnaires. Next, the results were used to prepare theclinical interview. In this interview, the presence <strong>of</strong> at least subsyndromal PD/A wasestablished, according to the guidelines as listed in Diagnostic <strong>and</strong> Statistical Manual<strong>of</strong> Mental Disorders (DSM-IV; American Psychiatric Association, 2000), i.e., respondentswere included only if they experienced at least one full or limited symptompanic attack in the previous month. Diagnoses were made by trained interviewers <strong>and</strong>checked by supervising researchers.<strong>The</strong> following inclusion criteria applied: age 18 years or older; no heightened risk<strong>of</strong> dissociation, psychosis, or suicide; no history <strong>of</strong> serious mental illness; no otherprevailing mental illnesses; absence <strong>of</strong> a medical condition that might explain panicsymptoms; no drug abuse; no use <strong>of</strong> neuroleptic medication; no use <strong>of</strong> anxiolyticsor antidepressants for less than 3 months or use <strong>of</strong> unstable doses (i.e., clients tookmedications as prescribed <strong>and</strong> in the targeted dosage); <strong>and</strong> no concurrent othertreatment. Excluded respondents were referred to their general practitioner, toother mental health institutions or to other Web-<strong>CBT</strong> programs. Eligible respondentsdownloaded, signed <strong>and</strong> returned an Informed Consent form.Risk <strong>of</strong> dissociation was assessed using the Somat<strong>of</strong>orm Dissociation Questionnaire(SDQ-5; citeNPNijenhuis1997). Respondents who scored above the cut-<strong>of</strong>f (8),completed the more specific Dissociation Questionnaire (DIS-Q) (V<strong>and</strong>erlinden, vanDyck, V<strong>and</strong>ereycken, & Vertommen, 1991; cut-<strong>of</strong>f: 3.0). <strong>The</strong> Screening Device forPsychotic Disorder (SDPD; Lange, Schrieken, et al., 2000) was used to assess the risk<strong>of</strong> psychotic episodes, with a cut-<strong>of</strong>f value <strong>of</strong> 5 on the Hallucination scale. Hypochondriasiswas assessed using the Whitely Index (Speckens, Spinhoven, Sloekers, Bolk, &van Hemert, 1996; cut-<strong>of</strong>f: 15). <strong>The</strong> occurrence <strong>of</strong> a prevailing posttraumatic stressdisorder was assessed using the Dutch version <strong>of</strong> the Impact <strong>of</strong> Events Scale - Revised(IES-R; Weiss & Marmar, 1996; cut-<strong>of</strong>f 36: Neal et al., 1994). Obsessive compulsive
4.2. Method 67disorder, social phobia <strong>and</strong> specific phobia, <strong>and</strong> bipolar disorder were signalled usingseven items from the Diagnostic Interview Schedule (DIS: Helzer & Robins, 1988).<strong>The</strong>rapists. <strong>The</strong> therapists were 7 graduate students in clinical psychology, 2 postgraduatestudents, <strong>and</strong> 2 psychologists. <strong>The</strong>y were supervised by two senior specialistsin web-<strong>CBT</strong>. All therapists had followed advanced courses in <strong>CBT</strong>, <strong>and</strong> received additionaltraining in administering web-<strong>CBT</strong>. <strong>The</strong>y were taught how to use the feedbacktemplates <strong>of</strong> the manual, to increase motivation by adopting a stimulating emphaticattitude, to avoid the pitfalls <strong>of</strong> electronic, text-based communication (e.g., Brennan& Ohaeri, 1999) <strong>and</strong> to pr<strong>of</strong>it from the asynchronous nature <strong>of</strong> the communication toenhance the quality <strong>of</strong> the feedback (i.e. by discussing cases with one another or withthe supervisor). Participants were assigned to therapists by the supervisor based onthe availability <strong>of</strong> the therapists.4.2.3 Outcome measuresPrimary outcome measures were the self-rate version <strong>of</strong> the Panic Disorder SeverityScale (PDSS-SR; Houck et al., 2002; Shear et al., 2001) <strong>and</strong> a one-week Panic Diary.Secondary measures were the Avoidance when ALone subscale <strong>of</strong> the Mobility Inventory(MI-AAL; Chambless, Caputo, Bright, & Gallager, 1984), the Agoraphobic CognitionsQuestionnaire <strong>and</strong> the Body Sensations Questionnaire (ACQ/BSQ; Chambless et al.,1984) <strong>and</strong> the Depression Anxiety Stress Scales (DASS-42; Lovibond & Lovibond, 1995).For all measures, higher scores indicate greater symptom severity.Panic diary. In the Panic Diary, participants monitored panic attacks occurring ina one-week period. Participants were instructed to report each distinct period thatwas characterized by a sudden onset <strong>of</strong> intense apprehension, fearfulness, or terror,possibly associated with feelings <strong>of</strong> impending doom (American Psychiatric Association,2000). <strong>The</strong>y were asked to note the occurrence <strong>of</strong> each attack <strong>and</strong> to rate theattack severity (on a 1-10 scale) <strong>and</strong> the specific symptoms experienced during theattack. To this end, participants checked each <strong>of</strong> 13 key symptoms <strong>of</strong> panic disorderoccurring during the attack, e.g., “palpitations, pounding heart or accelerated heartrate”, “trembling or sweating”. Three outcome measures were derived from the
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142 Summaryof the introduction prov
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ReferencesAben, I., Verhey, F., Lou
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References 159Bickel, R. (2007). Mu
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References 161apy Research, 1(2), 8
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References 163Hay, P. P., Bacaltchu
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References 165for bulimia nervosa:
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References 167Mond, J. M., Hay, P.
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References 169(2003). The developme
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References 171of change in psycholo
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DankwoordAlleen mijn naam staat op
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Dankwoord 175en Janneke Broeksteeg
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178 Curriculum VitaeLange, A., & Ru