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DOI: 10.3310/hta17010 Health Technology Assessment 2013 Vol. 17 No. 1TABLE 14 Index <strong>and</strong> reference st<strong>and</strong>ard tests used in studies <strong>of</strong> myoglobinStudyIndex testanalyser <strong>and</strong> timing Threshold (µg/l) Reference test assay <strong>and</strong> timingReference Tn diagnosticthreshold (µg/l)MI prevalence insample (%)Amodio 2007 52 Dade Behring Stratus CS 68 <strong>and</strong> 86 TNT; assay <strong>and</strong> timing not specified 0.07 21Body 2011 57 Alere Fluorescenceimmunoassay107 Roche Diagnostics, Elecsys at 12 hours from symptoms 0.01 18Cete 2010 58 Not stated 52 (women), 81 (men) TnT; assay not reported; 6 hours 0.1 33Di Serio 2005 63 Evidence Investigator 73.4 ESC/ACC, not further specified Not specified 53Ecollan 2007 64 Biosite Triage ® 150 Dade Behring TnI test at any time point over 24 hours 0.07 51Eggers 2004 18 Dade Behring Stratus CS 98 (men), 56 (women) Abbott AxSYM TnI; within 24 hours 0.1 22Garcia- Dade Dimension 92 (men), 76 (women) Dimension Analyser TnI, timing not stated 0.6 392011 49ValdecasasHjortshoj Roche Elecsys 51 (women), 72 (men) Roche Elecsys TnT after 6 to 9 hour <strong>and</strong> 12–24 hours 0.03 332010 68Ilva 2005 69 Innotrac Aio 150 Bayer Diagnostics TnI up to 24 hours 0.3 37Keller 2010 71 Not stated 107 Roche TnT or Siemens Dimension RxL TnI within 6 hours <strong>of</strong>admission0.3 (TnT)0.14 (TnI)29Liao 2009 74 Not stated 70 NR 1 73Mion 2007 77 Evidence ® Cardiac Panel 87 DimensionRxL TnI, timing not specified0.15 32Penttilä 2002 79 Hitachi 717 65 (men), 55 (women) Abbott IMx TnT at two different time points during72 hours0.1 30ACC, American College <strong>of</strong> Cardiology; ESC, European Society <strong>of</strong> Cardiology; NR, not reported.© Queen’s Printer <strong>and</strong> Controller <strong>of</strong> HMSO 2013. This work was produced by Goodacre et al. under the terms <strong>of</strong> a commissioning contract issued by the Secretary <strong>of</strong> Statefor Health. This issue may be freely reproduced for the purposes <strong>of</strong> private research <strong>and</strong> study <strong>and</strong> extracts (or indeed, the full report) may be included in pr<strong>of</strong>essional journalsprovided that suitable acknowledgement is made <strong>and</strong> the reproduction is not associated with any form <strong>of</strong> advertising. Applications for commercial reproduction should beaddressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials <strong>and</strong> Studies Coordinating Centre, Alpha House, University <strong>of</strong> Southampton SciencePark, Southampton SO16 7NS, UK.47

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