Systematic review, meta-analysis and economic modelling of ...
Systematic review, meta-analysis and economic modelling of ...
Systematic review, meta-analysis and economic modelling of ...
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DOI: 10.3310/hta17010 Health Technology Assessment 2013 Vol. 17 No. 1Study Study typePopulation: age (years)<strong>and</strong> sex Inclusion criteria Exclusion criteriaTime fromsymptoms(hours)No. <strong>of</strong>patientsLiao 2009 74 Single centre, China Mean age 69; 54 (73%) male Onset <strong>of</strong> acute chest pain <strong>and</strong>/or dyspnoea lasting for at least20 minutes within the last 3 hours,age > 18 yearsNone reported 2.2 (IQR1.5–2.9)(median)74Mad 2007 75 Single centre,AustriaMean age 58; 213 (76%)maleOnset <strong>of</strong> acute chest pain <strong>and</strong>/or dyspnoea lasting for at least20 minutes within the last 24 hours,age > 18 yearsNone reported 3 (IQR 2–6)(median)280McCann 2008 76 Multicentre,Northern Irel<strong>and</strong>Mean age 63; 281 (68%)maleIschaemic type chest pain within24 hoursAge < 18 years, interhospitaltransfer, <strong>and</strong> previous participation inthe study5.3 (median) 415Mion 2007 77 Single centre, Italy Mean age 63; 88 (67%) male Non-consecutive patients with chestpainNone reported 3.8 (range,1.5–13.0)(median)132Naroo 2009 78 Single centre,United ArabEmiratesAge not reported; 627 (79%)maleTypical cardiac chest pain within20 minutes to 12 hoursSTEMI, renal disease, age < 20 years NR 791Valle 2008 82 Multicentre, Spain Mean age 65; 287 (68%)maleSuspected ACS with symptomsbetween 20 <strong>and</strong> 180 minutes afterpresentationNone reported 1.2 (mean) 419IQR, interquartile range; NR, not reported.© Queen’s Printer <strong>and</strong> Controller <strong>of</strong> HMSO 2013. This work was produced by Goodacre et al. under the terms <strong>of</strong> a commissioning contract issued by the Secretary <strong>of</strong> Statefor Health. This issue may be freely reproduced for the purposes <strong>of</strong> private research <strong>and</strong> study <strong>and</strong> extracts (or indeed, the full report) may be included in pr<strong>of</strong>essional journalsprovided that suitable acknowledgement is made <strong>and</strong> the reproduction is not associated with any form <strong>of</strong> advertising. Applications for commercial reproduction should beaddressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials <strong>and</strong> Studies Coordinating Centre, Alpha House, University <strong>of</strong> Southampton SciencePark, Southampton SO16 7NS, UK.37
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