Systematic review, meta-analysis and economic modelling of ...

More documents

Recommendations

Info

Appendix 7Lambda (λ), £ Prob NoT Prob 10% Prob 99th Prob Hi SensProb 10-hourTrop35,000 0 0.0435 0.0979 0.6050 0.253636,000 0 0.0400 0.0947 0.5997 0.265637,000 0 0.0380 0.0909 0.5943 0.276838,000 0 0.0361 0.0874 0.5875 0.289039,000 0 0.0347 0.0840 0.5815 0.299840,000 0 0.0333 0.0814 0.5759 0.309441,000 0 0.0316 0.0776 0.5720 0.318842,000 0 0.0303 0.0743 0.5644 0.331043,000 0 0.0293 0.0724 0.5579 0.340444,000 0 0.0282 0.0697 0.5525 0.349645,000 0 0.0271 0.0674 0.5459 0.359646,000 0 0.0263 0.0656 0.5392 0.368947,000 0 0.0251 0.0643 0.5335 0.377148,000 0 0.0243 0.0623 0.5262 0.387249,000 0 0.0233 0.0597 0.5220 0.395050,000 0 0.0228 0.0589 0.5182 0.4001Prob 10%, probability that using standard troponin at presentation with a 10% coefficient of variation threshold is costeffective;Prob 10-hour trop, probability that using standard troponin at 10 hours is cost-effective; Prob 99th, probabilitythat using standard troponin at presentation with a 99th percentile threshold is cost-effective; Prob Hi Sens, probabilitythat using high-sensitivity troponin at presentation is cost-effective; Prob NoT, probability that no testing or treatment iscost-effective.170NIHR Journals Library
DOI: 10.3310/hta17010 Health Technology Assessment 2013 Vol. 17 No. 1Probability of cost-effectiveness in once-daily ward scenarioLambda (λ), £ Prob NoT Prob 10% Prob 99th Prob Hi SensProb 10-hourtrop0 1 0 0 0 01000 1 0 0 0 02000 1 0 0 0 03000 0.5785 0.4185 0.0030 0 04000 0.0014 0.7478 0.2489 0.0019 05000 0.0001 0.6277 0.3513 0.0209 06000 0 0.5445 0.3918 0.0637 07000 0 0.4735 0.4038 0.1227 08000 0 0.4191 0.3959 0.1850 09000 0 0.3693 0.3821 0.2486 010,000 0 0.3286 0.3677 0.3037 011,000 0 0.2926 0.3503 0.3569 0.000212,000 0 0.2657 0.3336 0.4005 0.000213,000 0 0.2412 0.3171 0.4408 0.000914,000 0 0.2216 0.3020 0.4750 0.001415,000 0 0.2041 0.2881 0.5051 0.002716,000 0 0.1894 0.2741 0.5317 0.004817,000 0 0.1757 0.2623 0.5548 0.007218,000 0 0.1639 0.2518 0.5735 0.010819,000 0 0.1549 0.2438 0.5873 0.014020,000 0 0.1457 0.2353 0.5997 0.019321,000 0 0.1377 0.2281 0.6099 0.024322,000 0 0.1300 0.2188 0.6206 0.030623,000 0 0.1223 0.2122 0.6291 0.036424,000 0 0.1163 0.2039 0.6365 0.043325,000 0 0.1112 0.1970 0.6414 0.050426,000 0 0.1058 0.1899 0.6464 0.057927,000 0 0.1004 0.1829 0.6493 0.067428,000 0 0.0964 0.1759 0.6517 0.076029,000 0 0.0916 0.1707 0.6521 0.085630,000 0 0.0883 0.1647 0.6547 0.092331,000 0 0.0840 0.1576 0.6553 0.103132,000 0 0.0805 0.1512 0.6529 0.115433,000 0 0.0770 0.1451 0.6521 0.125834,000 0 0.0739 0.1397 0.6520 0.1344© Queen’s Printer and Controller of HMSO 2013. This work was produced by Goodacre et al. under the terms of a commissioning contract issued by the Secretary of Statefor Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journalsprovided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should beaddressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton SciencePark, Southampton SO16 7NS, UK.171
Page 1:
Health Technology AssessmentVOLUME
Page 7:
DOI: 10.3310/hta17010 Health Techno
Page 10 and 11:
ContentsAppendix 5 Expected discoun
Page 13 and 14:
Page 15 and 16:
Page 17 and 18:
Page 19:
Page 22 and 23:
BackgroundTABLE 1 Hospital admissio
Page 24 and 25:
Background2. investigation of the c
Page 26 and 27:
BackgroundComputed tomographic coro
Page 28 and 29:
Research questionsiii. the diagnost
Page 30 and 31:
Assessment of diagnostic and progno
Page 32 and 33:
Page 34 and 35:
Page 36 and 37:
Page 38 and 39:
Page 40 and 41:
Page 42 and 43:
Page 44 and 45:
Page 46 and 47:
Page 48 and 49:
Page 50 and 51:
Page 52 and 53:
Page 54 and 55:
Page 56 and 57:
Page 58 and 59:
Page 60 and 61:
Page 62 and 63:
Page 64 and 65:
Page 66 and 67:
Page 68 and 69:
Page 70 and 71:
Page 72 and 73:
Page 74 and 75:
Page 76 and 77:
Page 78 and 79:
Page 80 and 81:
Page 82 and 83:
Page 84 and 85:
Page 86 and 87:
Page 88 and 89:
Page 91 and 92:
Page 93 and 94:
Page 95 and 96:
Page 97 and 98:
Page 99 and 100:
Page 101 and 102:
Page 103 and 104:
Page 105 and 106:
Page 107 and 108:
Page 109 and 110:
Page 111 and 112:
Page 113 and 114:
Page 115 and 116:
Page 117 and 118:
Page 119 and 120:
Page 121 and 122:
Page 123 and 124:
Page 125:
Page 128 and 129:
Discussionspecificity were 62% (95%
Page 130 and 131:
Discussionneed for revascularisatio
Page 132 and 133:
Discussionchanges in sensitivity an
Page 134 and 135:
Discussionuncertainty about these p
Page 136 and 137:
Discussiontroponin assays have bett
Page 138 and 139:
ConclusionsSuggested research prior
Page 141 and 142: DOI: 10.3310/hta17010 Health Techno
Page 151: DOI: 10.3310/hta17010 Health Techno
Page 154 and 155: Appendix 144. heart-type fatty acid
Page 156 and 157: Appendix 1135. interleukin 33.mp. (
Page 158 and 159: Appendix 147. 37 and 45 (529)48. li
Page 164 and 165: Appendix 313. Fernandez Portales JG
Page 166 and 167: Appendix 346. Luscher MS, Ravkilde
Page 168 and 169: Appendix 316. Rao SV, Ohman EM, Gra
Page 198 and 199: Appendix 9Clinical diagnosis of NST
Page 200 and 201: Appendix 9respectively. Exercise EC
Page 202 and 203: Appendix 93. Two reviewers will mak
Page 204 and 205: Appendix 9The methodology used in t
Page 206 and 207: Appendix 9ES (Information Resources
Page 208: Appendix 923. Westwood ME, Whiting
show all

Systematic review, meta-analysis and economic modelling of ...

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?