Systematic review, meta-analysis and economic modelling of ...

DOI: 10.3310/hta17010 Health Technology Assessment 2013 Vol. 17 No. 1Appendix 6 Cost-effectiveness of addingalternative biomarkers to troponinTroponin aloneBiomarker combinationStudyCosts, £ (95% CI) QALYs (95% CI) Costs, £ (95% CI) QALYs (95% CI)Body 2011 57 1,420,364(1,409,967 to1,430,762)26,295.56(26,266.8 to 26,234.32)1,697,541(1,686,216 to1,708,865)26,358.44(26,330.01 to26,386.87)Haltern2010 67 1,560,158(1,548,772 to1,571,543)26,349.19(26,321.78 to26,376.60)1,953,948(1,941,595 to1,966,300)26,379.20(26,350.30 to26,408.11)McCann2008 76 1,614,259(1,602,809 to1,625,708)26,349.09(26,322.15 to26,376.03)1,720,365(1,708,261 to1,732,468)26,374.48(26,346.03 to26,402.93)Mion 2007 77 1,473,403(1,462,493 to1,484,312)26,314.38(26,286.22 to26,342.54)1,628,844(1,617,067 to1,640,622)26,347.07(26,138.76 to26,375.39)Keller 2010 71 1,522,637(1,511,247 to1,534,028)26,327.06(26,298.69 to26,335.43)1,820,502(1,808,408 to1,832,596)26,362.73(26,332.55 to26,392.92)Reichlin2009 80 1,614,259(1,602,809 to1,625,708)26,349.09(26,322.15 to26,376.03)1,874,782(1,862,104 to1,887,460)26,382.12(26,353.68 to26,410.56)Keller 2010 71 1,522,637(1,511,247 to1,534,028)26,327.06(26,298.69 to26,335.43)1,713,718(1,701,987 to1,725,450)26,357.42(26,329.10 to26,385.73)Mion 2007 77 1,473,403(1,462,493 to1,484,312)26,314.38(26,286.22 to26,342.54)1,673,692(1,661,891 to1,685,493)26,356.08(26,326.76 to26,385.40)Collinson2006 48 1,716,809(1,704,484 to1,729,134)26,380.72(26,353.12 to26,408.32)2,199,735(2,187,170 to2,212,300)26,386.00(26,357.28 to26,414.71)Keating2006 70 1,570,178(1,558,422 to1,581,935)26,350.59(26,322.48 to26,378.71)2,344,645(2,332,475 to2,356,815)26,378.56(26,351.16 to26,405.97)© Queen’s Printer and Controller of HMSO 2013. This work was produced by Goodacre et al. under the terms of a commissioning contract issued by the Secretary of Statefor Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journalsprovided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should beaddressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton SciencePark, Southampton SO16 7NS, UK.165