Systematic review, meta-analysis and economic modelling of ...

DOI: 10.3310/hta17010 Health Technology Assessment 2013 Vol. 17 No. 1Appendix 1 Examples of search strategies usedBiomarkers review diagnostic accuracy search: a MEDLINE exampleChest pain population terms1. exp Chest Pain/ (43,381)2. (chest adj (pain or discomfort or tight* or pressure)).mp. (23,091)3. chest-pain.mp. (21,852)4. (cardiac adj pain).mp. (359)5. (thora* adj pain).mp. (1021)6. Acute Coronary Syndrome/(3223)7. acute coronary syndrome.mp. (7783)8. (acute adj coronary adj syndrome).mp. (7783)9. Angina, Unstable/ (7731)10. unstable angina.mp. (9934)11. (unstable adj2 angina).mp. (13,058)12. Myocardial Infarction/ (126,095)13. myocardial.mp. (307,141)14. infarct*.mp. (222,338)15. (myocardial adj infarction).mp. (163,555)16. heart attack.mp. (2540)17. (heart adj (arrest$or attack*)).mp. (29,166)18. (preinfarction or pre-infarction or (pre adj infarction)).mp. (408)19. or/1–18 (417,505)Biomarker terms20. creatine kinase.mp. or Creatine Kinase/ (27,627)21. ((creatine adj kinase) or (creatine adj phosphokinase)).mp. (29,176)22. creatine kinase MB.mp. (2589)23. creatine kinase MB isoenzyme.mp. (288)24. creatine kinase isoenzyme 2.mp. (8)25. creatine kinase 2.mp. (40)26. CK-2.mp. (161)27. CK-MB.mp. (2903)28. myoglobin.mp. or Myoglobin/ (11,827)29. C-Reactive Protein/(22,195)30. (c-reactive protein or c reactive protein).mp. (33,427)31. CRP.mp. (18,869)32. myeloperoxidase.mp. (12,827)33. mpo.mp. (6279)34. b-type natriuretic peptide.mp. (2624)35. type b natriuretic peptide.mp. (47)36. Natriuretic Peptides/ (847)37. (brain adj natriuretic peptide).mp. (5237)38. N terminal B type natriuretic peptide.mp. (36)39. BNP.mp. (4976)40. N-terminal-pro-natriuretic peptide.mp. (6)41. NTproBNP.mp. (99)42. NT-proBNP.mp. (1688)43. heart type fatty acid binding protein.mp. (196)© Queen’s Printer and Controller of HMSO 2013. This work was produced by Goodacre et al. under the terms of a commissioning contract issued by the Secretary of Statefor Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journalsprovided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should beaddressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton SciencePark, Southampton SO16 7NS, UK.133