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DOI: 10.3310/hta17010 Health Technology Assessment 2013 Vol. 17 No. 135. Brooks S.P GA. Alternative methods for monitoring convergence <strong>of</strong> iterative simulations. J ComputGraph Stat 1998;7:434–45.36. Alhashemi JA. Diagnostic accuracy <strong>of</strong> a bedside qualitative immunochromatographic test for acutemyocardial infarction. Am J Emerg Med 2006;24:149–55.37. Eggers KM, Ellenius J, Dellborg M, Groth T, Oldgren J, Swahn E, et al. Artificial neural networkalgorithms for early diagnosis <strong>of</strong> acute myocardial infarction <strong>and</strong> prediction <strong>of</strong> infarct size in chestpain patients. Int J Cardiol 2007;114:366–74.38. Kurz K. Comparison <strong>of</strong> the new high sensitive cardiac troponin T with myoglobin, h-FABP <strong>and</strong> cTnTfor early identification <strong>of</strong> myocardial necrosis in the acute coronary syndrome. Clin Res Cardiol2011;100:209–15.39. Macdonald SP, Nagree Y, Macdonald SPJ, Nagree Y. Rapid risk stratification in suspected acutecoronary syndrome using serial multiple cardiac biomarkers: a pilot study. Emerg Med Australas2008;20:403–9.40. Ooi S. Incremental value <strong>of</strong> heart-type fatty acid-binding protein, myoglobin, troponin T <strong>and</strong>electrocardiogram in rapid bedside diagnosis <strong>of</strong> acute coronary syndrome in chest pain patientspresenting to the emergency department. Society for Academic Emergency Medicine AnnualMeeting 2007. Acad Emerg Med 2007;14:S131.41. Rathore S, Knowles P, Mann AP, Dodds PA, Rathore S, Knowles P, et al. Is it safe to dischargepatients from accident <strong>and</strong> emergency using a rapid point <strong>of</strong> care Triple Cardiac Marker test to ruleout acute coronary syndrome in low to intermediate risk patients presenting with chest pain? Eur JIntern Med 2008;19:537–40.42. Sinha MK, Roy D, Gaze DC, Collinson PO, Kaski J. Role <strong>of</strong> ‘Ischemia Modified Albumin’, a newbiochemical marker <strong>of</strong> myocardial ischaemia, in the early diagnosis <strong>of</strong> acute coronary syndromes.Emerg Med J 2004;21:29–34.43. Eggers KM, Oldgren J, ld A, Lindahl B, Eggers KM, Oldgren J, et al. Combining different biochemicalmarkers <strong>of</strong> myocardial ischemia does not improve risk stratification in chest pain patients comparedto troponin I alone. Coron Artery Dis 2005;16:315–19.44. Eggers KM, Kempf T, Venge P, Wallentin L, Wollert KC, Lindahl B, et al. Improving long-term riskprediction in patients with acute chest pain: the Global Registry <strong>of</strong> Acute Coronary Events (GRACE)risk score is enhanced by selected non-necrosis biomarkers. Am Heart J 2010;160:88–94.45. Mockel M, Muller R, Vollert JO, Muller C, Danne O, Gareis R, et al. Lipoprotein-associatedphospholipase A for early risk stratification in patients with suspected acute coronary syndrome: amulti-marker approach. Clin Res Cardiol 2007;96:604–12.46. Body R, Phil P. Low soluble P-selectin may facilitate early exclusion <strong>of</strong> acute myocardial infarction.Clin Chim Acta 2011;412:614–18.47. Brown AM, Wu AH, Clopton. ST2 in emergency department chest pain patients with potentialacute coronary syndromes. Ann Emerg Med 2007;50:153–8.48. Collinson PO, Gaze DC, Bainbridge K, Morris F, Morris B, Price A, et al. Utility <strong>of</strong> admissioncardiac troponin <strong>and</strong> ‘ischemia modified albumin’ measurements for rapid evaluation <strong>and</strong>rule out <strong>of</strong> suspected acute myocardial infarction in the emergency department. Emerg Med J2006;23:256–61.49. Garcia-Valdecasas S, Ruiz-Alvarez MJ, Garcia DT, De Pablo. Diagnostic <strong>and</strong> prognostic value <strong>of</strong>heart-type fatty acid-binding protein in the early hours <strong>of</strong> acute myocardial infarction. Acta Cardiol2011;66:315–21.50. Ilva T, Lund J, Porela P, Mustonen H, Voipio-Pulkki LM, Eriksson S, et al. Early markers <strong>of</strong> myocardialinjury: cTnI is enough. Clin Chim Acta 2009;400:82–5.© Queen’s Printer <strong>and</strong> Controller <strong>of</strong> HMSO 2013. This work was produced by Goodacre et al. under the terms <strong>of</strong> a commissioning contract issued by the Secretary <strong>of</strong> Statefor Health. This issue may be freely reproduced for the purposes <strong>of</strong> private research <strong>and</strong> study <strong>and</strong> extracts (or indeed, the full report) may be included in pr<strong>of</strong>essional journalsprovided that suitable acknowledgement is made <strong>and</strong> the reproduction is not associated with any form <strong>of</strong> advertising. Applications for commercial reproduction should beaddressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials <strong>and</strong> Studies Coordinating Centre, Alpha House, University <strong>of</strong> Southampton SciencePark, Southampton SO16 7NS, UK.123

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