Cornea - ARVO

ARVO 2013 Annual Meeting Abstracts by Scientific Section/Group - CorneaFODE staining of sites where Schirmer test II was performed(arrows). Photos taken after: (A) 3 minutes (B) 5 minutes.Commercial Relationships: Po-Ting Yeh, None; Ben J. Glasgow,None; Richard Casey, NoneSupport: NIH EY11224 (BG), EY000331 (Core), NIH S10-RR023718 A (Shared Instrumentation Grant) and the Edith and LewWasserman Professorship (BG)FIGURE 1. Flowchart of the step approach for identifying riskfactors of dry eye using univariate and multivariate analysis.Program Number: 933 Poster Board Number: B0238Presentation Time: 1:00 PM - 2:45 PMFactors associated with dry eye: The Korea National Health andNutrition Examination Survey 2010Tyler Hyung Taek Rim 1 , Ji Min Ahn 2 , Sangchul Yoon 1 , Tae-im Kim 1 ,Eung Kweon Kim 1 , Kyoung Yul Seo 1 . 1 Department ofOphthalmology, Yonsei University College of Medicine, Seoul,Republic of Korea; 2 Ophthalmology, Siloam Eye Hospital, Seoul,Korea, Seoul, Republic of Korea.Purpose: To assess socio-demographic and health-related risk factorsassociated with dry eye.Methods: In 2010, a total of 5,726 randomly selected nationalrepresentative participants of the Korea National Health and NutritionExamination Survey underwent additional ophthalmologicexaminations by the Korean Ophthalmologic Society. Subjects wereasked to respond to a question of “Until now have you ever beendiagnosed before of having dry eye, either eye, by a doctor?” withpossible choices of “no” or “yes.” Independent variables weredivided into four categories: 1) socio-demographic factors, 2) healthexamination variables, 3) health behavioral risk factors and 4)variables concerning the eyes. The risk factors for dry eye wereidentified by using a multivariate logistic regression analysis.Results: The prevalence of dry eye was 8.2% (95% confidenceinterval (CI) 7.3-9.2) in subjects aged 19 or older. History of any eyesurgeries (adjusted Odds Ratio (aOR)=2.2, 95% CI, 1.7-2.8), femalesex (aOR=2.2, 95% CI, 1.5-3.3), extremely stressful status(aOR=1.8,95% CI, 1.0-3.1), and hypercholesterolemia of ≥240 mg/dL(aOR=1.3, 95% CI, 1.0-1.7) were independent risk factors for dryeye. Binge alcohol users (aOR=0.6, 95% CI, 0.5-0.9) and subjectswith occupations of farming, fishing, and forestry (aOR=0.2, 95% CI,0.1-0.4) were less likely to have dry eye compared to their referencegroups of non-drinkers and subjects with occupations inadministration, management or white-collar professionals,respectively. Among subjects who received an eye surgery, ptosissurgery (aOR = 6.2, 95% CI, 1.4-27.1), cataract surgery(aOR = 1.8,95% CI, 1.2-2.6), and refractive surgery(aOR=2.9, 95% CI, 1.8-4.5)were important risk factors.Conclusions: Ophthalmologists should be aware that pastexperiences of eye surgeries could be one of the most important riskfactors of dry eye, and should focus on treating dry eye problems insubjects who will receive or have already received an eye surgery.FIGURE 2. An association between type of eye surgery and dry eye.Commercial Relationships: Tyler Hyung Taek Rim, None; Ji MinAhn, None; Sangchul Yoon, None; Tae-im Kim, None; EungKweon Kim, None; Kyoung Yul Seo, NoneSupport: The authors state that they have no financial or conflicts ofinterest to disclose.Program Number: 934 Poster Board Number: B0239Presentation Time: 1:00 PM - 2:45 PMPrevalence of asymptomatic dry eye in patients with CollagenVascular Diseases in South IndiaRAMYA RAVINDRAN, Kalpana Suresh, Varshini Varadaraj.Ophthalmology, SRMC and RI, Chennai, India.Purpose: Dry Eye Syndrome (DES) is common in patients withcollagen vascular disorders. The purpose of this study was to identifyasymptomatic DES in patients with collagen vascular disorders inSouth India. In our part of the world, awareness regarding theimplications of late diagnosis is still lacking. The objectives were toidentify DES, classify it's severity based on the ocular surfaceintegrity and to delineate the sub set that had not undergone a priorophthalmic evaluation.Methods: A prospective, cross sectional, non interventional,observational study was conducted in a university hospital. 75patients diagnosed with various collagen vascular disorders with noocular complaints from the departments of General medicine,Pediatrics and Rheumatology formed the study group. 75 age and sexmatched controls were used for comparison. Patients with local andsystemic conditions that contribute to DES were excluded. Schirmer'stest, TBUT and rose bengal (RB) staining were performed and scoredaccording to the Van Bijsterveld scoring system. History of their lastophthalmic visit was noted. The Mann Whitney U test was used forstatistical analysis.©2013, Copyright by the Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Go to iovs.org to access the version of record. For permissionto reproduce any abstract, contact the ARVO Office at arvo@arvo.org.