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S16 From whence comes HSDD? - The Journal of Family Practice

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Case studyconsideration is that personal distress must be present toestablish a diagnosis <strong>of</strong> <strong>HSDD</strong>. 5,6<strong>The</strong> approach to management should address anyfactors that might be amenable to intervention, whetheror not they constitute the primary cause <strong>of</strong> the complaint<strong>of</strong> loss <strong>of</strong> sexual desire. In A.J.’s case, a consultation withher psychiatrist is in order to discuss the possible strategiesto lessen the potential impact <strong>of</strong> her depressive symptomsand antidepressant therapy on her sexual function.Her complaints <strong>of</strong> vasomotor symptoms and vaginaldryness suggest that she may benefit from systemic estrogentherapy to improve her sleep and reduce daytimefatigue and/or local estrogen therapy to decrease pain onintercourse by increasing vaginal lubrication. However,estrogen therapy does not directly affect sexual desire, sothe patient’s complaints <strong>of</strong> low desire may well persist. IfReferences1. Basson R, Berman J, Burnett A, et al. Report <strong>of</strong> theInternational Consensus Development Conferenceon Female Sexual Dysfunction: definitionsand classifications. J Urol. 2000;163:888-893.2. Bonierbale M, Lancon C, Tignol J. <strong>The</strong> ELIXIRstudy: evaluation <strong>of</strong> sexual dysfunction in 4,557depressed patients in France. Curr Med Res Opin.2003;19:1114-11224.3. Kennedy SH, Dickens SC, Eisfeld BS, et al.Sexual dysfunction before antidepressanttherapy in major depression. J Affect Disord.1999;56:2001-2008.4. Meston CM, Bradford A. Sexual dysfunctions inwomen. Annu Rev Clin Psychol. 2007;3:233-256.5. American Psychiatric Association. Diagnosticand Statistical Manual <strong>of</strong> Mental Disorders. 4thedition, text revision. Washington, DC: AmericanPsychiatric Press; 2000.6. Basson R, Schultz WW. Sexual sequelae <strong>of</strong> generalmedical disorders. Lancet. 2007;369:409-424.7. Simon J, Braunstein G, Nachtigall L, et al. Testosteronepatch increases sexual activity and desireso, a trial (<strong>of</strong>f-label) <strong>of</strong> testosterone therapy may be appropriate,as testosterone treatment may be effective insignificantly increasing sexual desire and decreasing distressin naturally menopausal women with <strong>HSDD</strong> whenused concomitantly with estrogen replacement therapy. 7Testosterone therapy, in combination with estrogen, hasalso been shown to improve arousability, fantasy, orgasm,and overall sexual satisfaction in women with <strong>HSDD</strong>. 8 Arecent trial investigating the use <strong>of</strong> testosterone alone innaturally menopausal women with low desire has demonstratedmodest dose-dependent improvements in sexualsatisfaction with this therapy. 9 nDisclosureDr. Parish is a consultant for Boehringer Ingelheim Pharmaceuticals, Inc.,and Wyeth.in surgically menopausal women with hypoactivesexual desire disorder. J Clin Endocrinol Metab.2005;90:5226-5233.8. Abdullah RT, Simon JA. Testosterone therapy inwomen: its role in the management <strong>of</strong> hypoactivesexual desire disorder. Int J Impotence Res.2007;19:458-463.9. Davis SR, Moreau M, Kroll R, et al. Testosteronefor low libido in postmenopausal women nottaking estrogen. N Engl J Med. 2008;359:2005-2017.instructions forreceiving creditContinuing Education Credit<strong>The</strong>re are 2 optionsfor receiving credit:1. A diagnosis <strong>of</strong> hypoactivesexual desire disorder (<strong>HSDD</strong>)in women involves:a. Overlap with another femalesexual dysfunctionb. Personal distressc. Decreased androgen levelsd. Transition through menopause2. Unlike <strong>HSDD</strong>, female sexualaversion disorder involves:a. Avoidance <strong>of</strong> all or almost allgenital sexual contactb. Inability to attain an adequatelubrication responsec. Personal distressd. Absence <strong>of</strong> sexual fantasies3. <strong>The</strong> prevalence <strong>of</strong> <strong>HSDD</strong>:a. Has been decreasing in recent years,according to epidemiologic studiesb. Has generally been reportedas 50 years old4. <strong>The</strong> PRESIDE study showed that themost common sexual complaintamong US women is:a. Low sexual desireb. Lack <strong>of</strong> sexual arousalc. Failure to achieve orgasmd. Erectile dysfunction in partnerOption 1:<strong>The</strong> DIME online enrollment systema. Please visit the url:www.DIMedEd.org/updates/<strong>HSDD</strong><strong>Family</strong><strong>Practice</strong>.htmlb. Complete the enrollment form,posttest, and evaluation.c. Successful completion <strong>of</strong> the selfassessmentis required to earnCategory 1 CME credit. SuccessfulPlease Circle or check the correct answer to each question.Release date: July 15, 2009Expiration date: July 15, 2010CME Posttest5. Survey data have revealed thatthe identification <strong>of</strong> female sexualdysfunction is hampered by:a. <strong>The</strong> rarity <strong>of</strong> these conditionsb. A lack <strong>of</strong> simple screening toolsc. Patient concerns that the physicianwill be embarrassedd. <strong>The</strong> reluctance <strong>of</strong> physicians torefer patients to specialists6. Which <strong>of</strong> the followingphysician characteristics was citedas increasing patient comfort indiscussing sexual issues,according to 90% <strong>of</strong> womensurveyed?a. Number <strong>of</strong> years in clinical practiceb. Solo vs group practicec. Having seen the patient befored. Never having seen the patient before7. Which <strong>of</strong> the following medicalsituations should prompt screeningfor female sexual problems?a. Diagnosis <strong>of</strong> diabetesb. Early postnatal periodc. Presence <strong>of</strong> adrenal diseased. All <strong>of</strong> the above8. A recent survey found that thevast majority <strong>of</strong> family physiciansscreen their female patientsfor <strong>HSDD</strong>.a. Trueb. Falsecompletion is defined as a cumulativescore <strong>of</strong> at least 70% correct. If youreceive a passing score, your certificate<strong>of</strong> credit will be made available to youimmediately.If you have difficulty accessing thelink, please contact the DIME <strong>of</strong>ficeat (312) 553-8000 or dimeservices@DIMedEd.orgOption 2:Complete this enrollment form,posttest, and evaluation form andmail them to:DIME 17771222 Merchandise Mart PlazaSuite 4-160Chicago, IL 60654A certificate <strong>of</strong> credit will be e-mailedor mailed to you within 6 weeks.Estimated time to complete activity: 1.25 hours9. Studies <strong>of</strong> pharmacologictherapies for <strong>HSDD</strong> haveshown that:a. Drugs used to treat erectiledysfunction in men are consistentlyeffective in womenb. Bupropion improves all measures<strong>of</strong> sexual functionc. Dopaminergic agents providethe greatest efficacyd. None <strong>of</strong> the above10. Which <strong>of</strong> the followingstatements is not true?a. Data have confirmed thattransdermal testosterone improvessymptoms <strong>of</strong> <strong>HSDD</strong>b. Estrogens have a greater impacton female sexual function thando androgensc. Studies <strong>of</strong> dehydroepiandrosteronein women with <strong>HSDD</strong> have yieldedconflicting resultsd. More data are needed todetermine whether flibanserin iseffective in women with <strong>HSDD</strong>S32 July 2009 / Vol 58, No 7 / Supplement to <strong>The</strong> <strong>Journal</strong> <strong>of</strong> <strong>Family</strong> <strong>Practice</strong> Copyright © 2009 Dowden Health Media and DIME www.jfponline.comSupplement to <strong>The</strong> <strong>Journal</strong> <strong>of</strong> <strong>Family</strong> <strong>Practice</strong> / Vol 58, No 7 / July 2009 S33

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