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who medicines strategy - libdoc.who.int - World Health Organization

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WHO MEDICINES STRATEGY 2004-2007 | 44R & DMost resources spent on “lifestyle” conditions and “me-too”<strong>medicines</strong>Figure 8:Challenges are present at every stage in the<strong>medicines</strong> chain>>CLINICAL TRIALSReal conflict of <strong>int</strong>erest between manufacturers and researchersGood clinical practices not always respected in poorer countriesAdverse findings not published or falsified>REGISTRATIONFalsification of safety dataBriberyFast-track registrationCounterfeitingMedicines for ‘orphan’ diseasesTax evasion and fiscal fraudMANUFACTURINGPATENTSExcessive extension on “best-selling” <strong>medicines</strong>Unlawful appropriation of royalties>PRICESVary between countriesArtificially inflated in some cases>DISTRIBUTIONMismanagement of goodsBriberyDONATIONSWHO guidelines not always respectedPROMOTIONDirect-to-consumer advertisingReal conflict of <strong>int</strong>erest between physician and manufacturersSubtle pressure on physicians

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