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who medicines strategy - libdoc.who.int - World Health Organization

who medicines strategy - libdoc.who.int - World Health Organization

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WHO MEDICINES STRATEGY 2004-2007 | 112WHO advocates 12 key<strong>int</strong>erventions to promote morerational use:1 Establishment of amultidisciplinary national body tocoordinate policies on medicineuse2 Use of clinical guidelines3 Development and use of nationalessential <strong>medicines</strong> listIrrational use of <strong>medicines</strong> is a major problemworldwide. WHO estimates that more than halfof all <strong>medicines</strong> are prescribed, dispensed or soldinappropriately, and that half of all patients failto take them correctly. The overuse, underuse ormisuse of <strong>medicines</strong> results in wastage of scarceresources and widespread health hazards.Examples of irrational use of <strong>medicines</strong> include:> use of too many <strong>medicines</strong> per patient (‘polypharmacy’)> inappropriate use of antimicrobials, oftenin inadequate dosage, for non-bacterialinfections> over-use of injections when oral formulationswould be more appropriate> failure to prescribe in accordance withclinical guidelines> inappropriate self-medication, often ofprescription-only <strong>medicines</strong>> non-adherence to dosing regimes.4 Establishment of drug andtherapeutics committees in districtsand hospitals5 Inclusion of problem-basedpharmacotherapy training inundergraduate curricula6 Continuing in-service medicaleducation as a licensurerequirement7 Supervision, audit and feedback8 Use of independent information on<strong>medicines</strong>9 Public education about <strong>medicines</strong>10 Avoidance of perverse financialincentives11 Use of appropriate and enforcedregulation12 Sufficient government expenditureto ensure availability of <strong>medicines</strong>and staff.

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