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Proceeding of the 4 rd International Symposium“NEW RESEARCH IN BIOTECHNOLOGY” USAMV Bucharest, Romania, 2011OD 500 nm1.510.5DEXTROSE CULTURE MEDIA MODIFIED STRAINEqn 8003 Gaussian(a,b,c,d)r^2=0.99869513 DF Adj r^2=0.99478052 FitStdErr=0.018920331 Fstat=255.12006a=0.044744129 b=0.75989211c=192.76906 d=45.7374431.510.5OD 500 nmFigure 14. Red azaphyloneproduction during thebiosynthesis in submerged mediawith dextrose and Monascussp.2. Measurement performed at500 nm00-0.5-0.50 50 100 150 200 250Time, hOD 420 nm1.510.5DEXTROSE CULTURE MEDIA MODIFIED STRAINEqn 8003 Gaussian(a,b,c,d)r^2=0.99891834 DF Adj r^2=0.99567338 FitStdErr=0.025487003 Fstat=307.83626a=0.078192263 b=0.90413132c=166.51642 d=32.9894711.510.5OD 420 nmFigure 15. Orange azaphyloneproduction during thebiosynthesis in submerged mediawith dextrose and Monascussp.2. Measurement performed at420 nm00-0.525 75 125 175Time, h-0.5OD 400 nm21.510.5DEXTROSE CULTURE MEDIA MODIFIED STRAINEqn 8003 Gaussian(a,b,c,d)r^2=0.99966372 DF Adj r^2=0.99865486 FitStdErr=0.019332854 Fstat=990.89053a=0.065608312 b=1.3232823c=177.17553 d=39.17736121.510.5OD 400 nmFigure 16. Yellow azaphyloneproduction during thebiosynthesis in submerged mediawith dextrose and Monascussp.2. Measurement performed at400 nm00-0.525 75 125 175Time, h-0.590
Proceeding of the 4 rd International Symposium“NEW RESEARCH IN BIOTECHNOLOGY” USAMV Bucharest, Romania, 2011Figura 17 Citrinin production during thebiosynthesis in submerged media with dextroseand Monascus sp.1Figura 18 Citrinin production during thebiosynthesis in submerged media with dextroseand Monascus sp.2REFERENCES1. Espinosa, D. R., Webb, C., (2003), Submerged fermetation in wheat substrate for productionof Monascus pigments, Worl Journal of Microbiol. Biotechnol., 19, 329.2. Yuan, C.S., Lin, T.T.,Wang, J.J. Production of the secondary metabolites γamminobutyricacid and monacolin K by Monascus, (2003), J.Ind. Microbiol. Biotechnol., 30(1), 41-46..3. Satyanaraya, T., Maheswar, J.L.U.R, (1996), α Amilases, Protein Chemistry vol XII ed.Crabb, J.4. Wang, Y.Z., Xiu. L. J., Yu. G.Z., (2005), The variability of citrinin production in Monascus typecultures Food Microbiology, (22), 145-148,.5. Blanc, P. J., Loret, M. O., Goma, G., (1995).Production of citrinin by various species ofMonascus. Biotech. Lett., 17 : (3), 291-294,91
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