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New Researches in Biotechnology - Facultatea de Biotehnologii ...

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Proceed<strong>in</strong>g of the 4 rd International Symposium“NEW RESEARCH IN BIOTECHNOLOGY” USAMV Bucharest, Romania, 2011There are two pr<strong>in</strong>ciples <strong>in</strong> address<strong>in</strong>g stochastic programm<strong>in</strong>g:a) the pr<strong>in</strong>ciple of "wait and see" is <strong>in</strong>ten<strong>de</strong>d that the knowledge of probabilistic<strong>in</strong>formation about n-dimensional random vector, and distribution function, or somemoments (mean, variance), stochastic problem is then treated as a <strong>de</strong>term<strong>in</strong>istic problem,characterized by a probability distribution.b) The 'here and now "means choos<strong>in</strong>g a solution from the set of possible solutions thatmeet a certa<strong>in</strong> criterion of optimality, before study<strong>in</strong>g random variables <strong>in</strong>volved <strong>in</strong> theproblem.2.2. General formulation of optimization problemsThe optimization process is divi<strong>de</strong>d <strong>in</strong> three stages:- Problem <strong>de</strong>f<strong>in</strong>ition, <strong>in</strong> which one <strong>de</strong>f<strong>in</strong>e the system (process) to be optimized, thevariables that can be changed, the objective function to calculate the m<strong>in</strong>imum ormaximum, and limitations to be observed;- Construction of a mathematical mo<strong>de</strong>l to be used to calculate the objective function;- Choos<strong>in</strong>g of mathematical methods for f<strong>in</strong>d<strong>in</strong>g the m<strong>in</strong>imum or maximum objectivefunction.2.2.1. Problem <strong>de</strong>f<strong>in</strong>itionThe objective function is what we seek to maximize or m<strong>in</strong>imize. This is usually aneconomic function (e.g.: energy consumption, equipment size, production costs, capitalcosts, total cost, the duration of the recovery of money or the <strong>in</strong>ternal rate of return) or noneconomic(safety and reliability, product quality or <strong>de</strong>pen<strong>de</strong>nce work or often acomb<strong>in</strong>ation of these factors, weighted <strong>in</strong> some way reflect<strong>in</strong>g our priorities). Often, thegoal is to m<strong>in</strong>imize costs, therefore the objective function is called the "cost".The variables can be mo<strong>de</strong>led - <strong>de</strong>sign variables such as number, size and structuretypes of equipment or plants, or operational variables such as freezers and coolersprogramm<strong>in</strong>g, how to rotate refrigeration compressors or number of laps <strong>in</strong> a day. Thevariables can also be classified as cont<strong>in</strong>uous variables (or simple) and structural variables.The former tend to be more easily optimized, while structural variables (those which cannotconveniently be ma<strong>de</strong> <strong>in</strong> figures) are the most difficult to represent mathematically andtherefore most uncomfortable for optimization.The constra<strong>in</strong>s of optimization problems are: physical (laws of conservation ofenergy or materials, laws of thermodynamics), economical (capital available, the rate ofreturn or recovery time), technological (materials and technology available), and others arelegal and sociological.Basically a mathematical optimization problem (l<strong>in</strong>ear or nonl<strong>in</strong>ear programm<strong>in</strong>g) isto <strong>de</strong>term<strong>in</strong>ate maximum or m<strong>in</strong>imum (optimum) of a function that <strong>de</strong>pends on certa<strong>in</strong>variables, that respect the restrictions given.2.2.2. Construction of a mathematical mo<strong>de</strong>lThe optimization process is performed on a mathematical mo<strong>de</strong>l. It must establish aset of equations that expect the objective function (cost) and a set of variable valuestogether with a method of solv<strong>in</strong>g these equations. The equations are generally solved by anumerical procedure.107

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