Contenido - Infomed

ContenidoOct.- Dic. del 2002 Año 11 No. 4COMITÉ EDITORIALPresidentaConcepción Campa HuergoVicepresidenteGustavo Sierra GonzálezEditores EjecutivosOrlando Gutiérrez y Gilberto SotolongoAsesoresJuraj Ivanyi (UK) y Epifanio Selman (CU)Editor Biología MolecularArmando AcostaEditor InmunologíaArmando CádizEditor MicrobiologíaIsabel MartínezEditor EpidemiologíaJorge MenéndezEditor TecnologíaArturo TalaveraRedactor JefeVirginia BetancourtCorrección ReferenciasBertha PimientaTraducciónEloísa Le RiverendLos artículos originales de estapublicación son arbitrados.Se autoriza la reproducción de losmateriales originales publicados en estaRevista, siempre que se indique suprocedencia.El contenido de las informacionesaparecidas en esta Revista no expresanecesariamente la opinión de laInstitución.ISSN 1025-0298 (Versión Electrónica)Calle 212 No. 3112 e/ 31 y 37, La Lisa.Ciudad de La Habana. Cuba.Ap. 16017, Cod. 11600! (53-7) 271 6557Fax: (53-7) 33 6754E-mail: vaccimonitor@finlay.edu.cuWeb: http://www.finlay.edu.cuhttp://www.sld.cu/instituciones/finlay/publicaciones/vaccimonitor/vm.htmLos inmunológos latinoamericanos se aprestan para asistir al6to Congreso de la Asociación Latinoamericana de Inmunología (ALAI), aefectuarse en el Palacio de Convenciones, La Habana, Cuba, entre los días9 y 13 de diciembre del presente año.Este evento se ha concebido para que coincida con la celebración del3er Congreso Cubano de Inmunología, oportunidad propicia para dar aconocer sobre los avances en la investigación, tratamiento y prevenciónde enfermedades en Cuba.Se espera que profesionales provenientes de más de 40 países se den citaen este cónclave regional que contará también con la presencia deprestigiosos especialistas de otras latitudes.Por la importancia y la calidad científica de las contribuciones que allí sedebatirán, VacciMonitor ha considerado oportuno compilar en este númeroespecial, los resúmenes de los trabajos que serán presentados en ALAIHavana 2002.ORGANIZING COMMITTEE / COMITE ORGANIZADORPresidents / PresidentesJorge V. Gavilondo (Cuba; President / Presidente, ALAI); Gustavo Sierra (Cuba; President /E-mail: ALAI@finlay.edu.cuVicepresidents / VicepresidentesOliver Pérez (Cuba; General Secretary / Secretario General, ALAI, SCI); Clelia Riera (Argentina;Vice-president ALAI / Vice-presidente ALAI); Alberto Nieto (Uruguay; Past President ALAI /Presidente Anterior ALAI)Secretariat (alphabetical order) / Secretariado (orden alfabético)Reinaldo Acevedo; Marta Ayala (Treasurer ALAI / Tesorera ALAI); Julio Balboa; GustavoBracho;Mónica Bequet; Osmir Cabrera; Judith M. del Campo; Maribel Cuello; Alicia García(Conventions Center / Palacio de Convenciones); Danay Gil; Miriam Lastre (Treasurer SCI /Tesorera SCI); Tamara Rodríguez; Caridad Román (Havanatur SA)Support / AseguramientoCarlos Taboada Caridad Zayas Carlos CorchoNational Advisory Committee / Comité Asesor NacionalAgustín Lage; Carlos Silva; Antonio González-Griego; Catalino UstarizRuben Rodríguez-Gavaldá;Consuelo Macías; Sergio Arce; Alina Alerm; Luis Fonte;Jose L Fernández-Yero;Maria EugeniaAlonso Gustavo Kourí; Jose M. Ballester;Rolando Pérez;Eduardo Pentón;Rosa IslaRegional and International Scientific Advisory Committee / Comité Científico AsesorRegional e InternacionalFernando Goñi (Uruguay); Armando Peréz Puigbó (Venezuela); Alberto Nieto (Uruguay); VianneyOrtiz (Mexico); Marianna Newkirk (Canada); Ethel García Latorre; (México/México);JacquesLouis (WHO);Margarita Brizuela (Paraguay); Mohamed Daha (The Netherlands/Holanda);JuanCarlos Aguillón (Chile);Josef Smolen (Austria); Arturo Ferreira (Chile); Genevieve Milon;(France/Francia); Jorge Allende (RELAB); Anders Orn (Sweden/Suecia); Livia Lustig (Argentina);Fritz Melchers; Switzerland/Suiza); Carlos A. Fossati (Argentina); Ricardo Cardona (Colombia);Oscar Grau (RELAB); Luis F. García (Colombia); Rodrigo Correa de Oliveira (Brazil/Brasil); AlbertoPellegrini (PAHO/OPS); Jorge Kalil (Brazil); George das Reis (Brazil); Alejandro Afani (Chile);Leopoldo Santos (Mexico/México); José A Chabalgoity (Uruguay); Harmut Peter(Germany/Alemania); Jacob Natvig (Norway); Clelia Riera (Argentina)

RESÚMENESPLENARY CONFERENCESGustavo Sierra (Cuba)Philippa Marrack (USA)Parallel Plenary Conferences (Tuesday 10, Morning)First effective vaccine against B meningococcal disease based on aproteoliposome structureThe courtship between MHC and the T-cell receptorAgustin Lage (Cuba) Immunoregulation and cancer: the hurdles of complexity (Room 3)Louis Du Pasquier(Switzerland)Parallel Plenary Conferences (Tuesday 10, Afternoon)Masayuki Miyasaka(Japan)Anders Örn (Sweden)Origin and evolution of the vertebrate immune system (Room 4)Molecular determinants controlling tissue-specific lymphocyte homing -dogmas and enigmas (Room 3)Defining factors necessary to initiate and maintain chronic inflammatorydisorders in murine Chagas´ Disease (Room 4)Parallel Plenary Conferences (Wednesday 11, Morning)Jacques Louis(Switzerland)Marianna Newkirk(Canada)The murine model of infection with L. major as a tool to study geneticdifferences in Th subset development (Room 3)The Rheumatoid Factor response in infection and autoimmunity (Room4)Parallel Plenary Conferences (Wednesday 11, Afternoon)Mohamed Daha (TheNetherlands)Paul Kincade (USA)Parallel Plenary Conferences (Thursday 12, Morning)Nikolay Petrovsky(Australia)Innate immunity and the complement system in autoimmune disease(Room 3)Identification of the earliest lymphocyte precursors in bone marrow ofmouse and man (Room 4)Parallel Plenary Conferences (Thursday 12, Afternoon)Temporal compartmentalisation of the immune response (Room 4)Jorge Kalil (Brazil) Immunopathology of rheumatic heart disease (Room 3)Christopher Rudd (UK) Role of adaptors in TcR and co-receptor signaling (Room 4)Parallel Plenary Conferences ( Friday 13, Morning)Jorge V. Gavilondo(Cuba)Recombinant therapeutic antibodies (Room 3)Lindsay Dent (Australia) Eosinophils in health and disease (Room 4)Closing Keynote Address (Friday 13, Afternoon)Henry Metzger (USA)Policy for science, science for policy

ORAL SESSIONSTUMOR IMMUNOLOGY AND IMMUNOTHERAPY1. Nikolay Petrovsky (Australia) Computational modeling and prediction systems in clinical andexperimental immunology2. W. H. Fridman (France) Tumor immunological microenvironment: prognostic and therapeuticvalue3. Catherine Sautes-Fridman (France) Expression and biological roles of Fc gamma receptors inhuman metastatic melanoma4. Luis E. Fernández (Cuba) Acetylated and glycolilated GM3 cancer vaccine: an update5. Jose A. Chabalgoity (Uruguay) Designing new immunotherapies for cancer using liveattenuated salmonella as a vector for DNA vaccines6. Laszlo Radvanyi (Aventis-Pasteur) New antigens and vectors for therapeutic vaccination againstbreast cancer and tumor angiogenesis7. Ana M. Vázquez (Cuba) Evidences of an idiotypic network in the Neu Gc-containing gangliosidesystem: preclinical and clinical data8. Cornelis Melief (The Netherlands) Precision guiding of cytotoxic T lymhocytes responses forcancer therap9. Tania Crombet (Cuba) Epidermal growth factor based cancer vaccine for non-small cell lungcancer therapy: report from a phase I scale up trial10. Flavio Salazar Onfray (Chile) Detection of anti melanoma specific CTL in PBMC from melanomapatients treated with autologous dendritic cells loaded with tumor cell extracts11. Giselle Suárez (Cuba) Phase I clinical trial of the ganglioside cancer vaccine N-Acetyl-GM3/VSSP/Montanide ISA 51 in advanced breast cancer patients12. Marie C. Bene (France) Immunophenotyping of leukemias13. Gilbert C Faure (France) Tobacco exposure: local inflammation or acquired immune deficiency14. Carlos Barbas III (USA) Chemical approaches to cancer therapeutics15. James W. Larrick (USA) Novel approaches to reverse resistance to apoptosis in cancer16. Mayra Ramos (Cuba) 99mTc labeled anti-human EGF receptor antibody (ior EGF/R3) in patientswith tumors of epithelial origin17. Tania Crombet (Cuba) Use the anti EGF receptor antibody h-R3 in combination withradiotherapy in the treatment of advanced head and neck cancer18. Pedro López-Saura (Cuba) Interferons and neoplasia in Cuba19. AS Schanoski et al. (Brazil) WALKER 256 TUMOR MHC CLASS I EXPRESSION DURING THESHIFT FROM "A" VARIANT INTO THE IMMUNOGENIC "AR" VARIANT. SOP20. L Alaniz et al. (Argentina) CD44-HYALURONIC ACID INTERACTION MODULATESMETALLOPROTEINASES IN A T CELL MURINE LYMPHOMA AND IN INFLAMMATORYLEUKOCYTES. SOP21. MC Anazetti et al. (Brazil) TREATMENT OF LEUKEMIC CELLS (HL60) WITH DIMETHYLAMIDE-CROTONIN TRIGGERS APOPTOSIS DEPENDENT OF CASPASES -2 AND -9, BACTIVATION.SOPIMMUNOLOGY OF PARASITE DISEASES1. Manoel Barral Netto (Brazil) Immunology of human leishmaniasis2. Genevieve Milon (France) Parasitism, a rapid and renewed cross talk between parasites and theimmune system of their hosts: the example of Leishmania spp.3. Edgar Carvalho (Brazil) The role of host and parasite factors in the development of tegumentaryleishmaniasis4. Aldina Barral (Brazil) Molecular epidemiology of human leishmaniasis: natural immune responsesagainst saliva proteins derived from the insect vector5. CM Trujillo et al. (Colombia) CELL EXPRESSION OF COSTIMULATORY MOLECULES NODIFFERS IN PATIENTS WITH LOCALIZED CUTANEOUS LEISHMANIASIS AND ENDEMICALLY

EXPOSED ASYMPTOMATICS. SOP6. S Télles et al. (Venezuela) EXPRESSION OF PEPTIDE-HLA COMPLEXES IN INFECTEDMACROPHAGES WITH Leishmania Braziliensis. SOP7. H Goto et al. (Brazil) IMMUNOPATHOGENESIS OF GLOMERULONEPHRITIS IN VISCERALLEISHMANIASIS (VL) INVOLVES CD4+ T CELLS, IMMUNOGLOBULIN AND MODULATION OFAPOPTOSIS. SOP8. Rose Leke (Cameroon) Malaria during pregnancy: diagnosis and immune responses9. Arturo Ferreira (Chile) Trypanosoma cruzi Calreticulin: some immunomodulatory properties10. A Ruiz Espinosa et al. (Cuba) CONSTRUCTION AND EVALUATION OF IMMUNOGENICITY ANDINDUCED PROTECTION IN BALB/C MICE IMMUNIZED WITH A GENOMIC LIBRARY OFEXPRESSION OF TRYPANOSOMA CRUZI. SOP11. JC Sepulveda-Arias et al. (Colombia-Germany) STUDIES ABOUT IMMUNE RESPONSE IN RATSINFECTED WITH Toxoplasma gondii VIA MILK. SOP12. A. Rodríguez et al. (Cuba) SIGNIFICANT PROTECTIVE EFFECTS OF NAKED DNA BASEDIMMUNIZATION FROM LETHAL TOXOPLASMOSIS IN MICE. SOP13. Rodrigo Correa (Brazil) Mechanism of resistance and pathology in Schistosoma nansoniinfection14. Miguel Stadecker (USA) Schystosomiasis: a helminthic disease caused and shaped by the hostsimmune response15. David Pritchard (UK) The immunological challenge posed by human hookworm infections, andthe quest for vaccines16. G Ferragut et al. (Uruguay) ROLE OF IL-4 IN EXPERIMENTAL INFECTION BY THE HELMINTHEchinococcus granulosus. SOP17. A Olivos-García et al. (Mexico) AMEBIC CYSTEINE PROTEINASE 2 (EhCP2) PLAYS EITHER AMINOR OR NO ROLE IN TISSUE DAMAGE IN ACUTE EXPERIMENTAL AMEBIC LIVER ABSCESSIN HAMSTERS. SOP18. Luis Fonte Galindo et al. (Colombia) INTESTINAL AMEBIASIS. IMMUNOLOGICAL ANDBIOMOLECULAR DEMONSTRATION OF THE OVERESTIMATION OF A HEALTH PROBLEM. SOP19. M del P Jiménez et al. (Colombia) DIFFERENTIAL PHAGOCYTIC CAPACITY OF Nramp1 GENECONGENIC MACROPHAGE LINES TO THE INFECTION WITH CONIDIAS OF ParacoccidioidesBraziliensis. SOPIMMUNOLOGY OF VIRAL DISEASES1. Verena Muzio (Cuba) Hepatitis B prophylactic vaccines: realities and new perspectives2. Eduardo Pentón (Cuba) Therapeutic vaccine approaches to Hepatitis B infection3. Santiago Dueñas (Cuba) Development of therapeutic vaccines for Hepatitis C4. Antonio González Griego (Cuba) Considerations on diagnostic, prognostic and prophylaxistherapeuticintervention in Hepatitis type B5. Hugo Nodarse (Cuba) Treatment of viral diseases with Interferon in Cuba6. J Marante et al. (Cuba) IMPROVEMENT OF HCV-SPECIFIC IMMUNE RESPONSES USING ANEW VECTOR OF THE pMAE PLASMID SERIE. SOP7. E Esquivel et al. (Mexico) ANALYSIS OF B AND T CELL ACTIVATION IN MESENTERIC LYMPHNODES FROM MICE INFECTED WITH ROTAVIRUS. SOP8. Elopy Sibanda (Zimbabwe) HIV: diagnostic, clinic, and therapeutic aspects in Africa9. Carlos Duarte (Cuba) Induction of a Th1, CTL mediated immune response against HIV-1chimeric proteins with DNA and poxviral vectors10. Barbara Ensoli (Italy) Novel approaches for HIV/AIDS vaccine development: from basic scienceto human trials11. D Vázquez-Blomquist et al. (Cuba) MODIFIED VACCINIA VIRUS ANKARA (MVA) PRIMING ANDFOWLPOX VIRUS BOOSTER ELICIT STRONGER CTL RESPONSE IN MICE AGAINST AN HIV-1EPITOPE THAN DNA-POXVIRUS PRIME-BOOST APPROACH. SOP

12. A Alvarez et al. (Cuba) VIRAL LOADS AND PHENOTYPIC MARKERS OF HIV PROGRESSION INCUBAN PATIENTS. SOP13. E Iglesias et al. (Cuba) IMMUNIZATION WITH MAPs COUPLED TO CARRIERS: INFLUENCE OFTHE EPITOPIC DENSITY AND PRE-EXISTING IMMUNITY TO THE CARRIER. SOP14. V Kourí et al. (Cuba) KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS (KSHV)SEROPREVALENCE IN CUBAN POPULATIONS. SOP15. Gustavo Kouri (Cuba) Dengue. Situation in Latin America and the Caribbean - 200216. Eric Martínez (Cuba) Pathogenesis of Dengue Hemorrhagic Fever17. Guadalupe Guzmán (Cuba) Dengue vaccines, advances and challenges18. G Mellado Sánchez et al. (Mexico) EVALUATION OF IMMUNE RESPONSE OF INFECTEDDENGUE PATIENTS TO RECOMBINANT NS1 AND E PROTEINS. SOP19. MMB Moreno-Altamirano et al. (Mexico) GENE EXPRESSION IN HUMAN MACROPHAGESINFECTED WITH DENGUE VIRUS. SOP20. AB Pérez et al. (Cuba-EEUU) SERUM LEVELS OF IL-12, IL-10, RANTES AND NITRIC OXIDE INDENGUE VIRUS INFECTED PATIENTS. SOP21. B Sierra et al. (Cuba) THE RECOMBINANT DEN 2 ENVELOPE B DOMAIN ELICITS A STRONGSEROTYPE SPECIFIC LYMPHOPROLIFERATIVE RESPONSE IN MICE. SOPIMMUNOLOGY OF BACTERIAL DISEASES1. Stitaya Sirisinha (Thailand) Dendritic cell maturation and cytokine production induced byBurkholderia (pseudomonas) pseudomallei2. Narinder Mehra (India) Cytokine polarization in mycobacterial infections: MHC influences3. Stanley Ress (South Africa) Immune response to neonatal BCG vaccination4. David Pritchard (UK) Immune modulation by bacterial quorum sensing molecules, and theirapplication to immunological disease5. Vincent Wilson (UK) Further studies on the acute effect of bacterial 'quorum-sensing'molecules on porcine coronary arteries6. Narinder Mehra (India) Extreme MHC diversity and its implications on vaccination protocols7. R Pellegrino et al. (Uruguay) MrpA FIMBRIAL PROTEIN AS A PROTECTIVE ANTIGEN AGAINSTURINARY TRACT INFECTIONS. SOP8. Dietrich Kabelitz (Germany) Role of human gamma delta T lymphocytes in disease9. Vincent Wilson (UK) FMLP produces vasoactive effects in human and porcine blood vessels10. Oliver Pérez (Cuba) Immunological response induced by relevant protective bacterial antigens11. Marta González (Cuba) Immunogenicity, potency, and safety of an adsorbed trivalentLeptospira vaccine12. Luis García (Cuba) Advances in the research of Cuban Cholera vaccine13. Luis Riverón (Cuba) Vi polysaccharide typhoid vaccine14. Luis F. García (Colombia) Consequences of Mycobacterium tuberculosis (Mtb) infection onmacrophage functions15. Idrián García (Cuba) Use of recombinant human interferon gamma in patients with multidrugresistanttuberculosis16. Armando Acosta (Cuba) New strategies for tuberculosis vaccine development17. D Gil et al. (Colombia) MYCOBACTERIAL-INDUCED NECROSIS AND APOPTOSIS INMACROPHAGES FROM PATIENTS WITH TUBERCULOSIS (TB) AND HEALTHY CONTROLSDEPEND ON TNF-alfa/IL-10 BALANCE. SOP18. B Rivas-Santiago et al (Mexico-USA). INDUCTION OF HUMAN b-DEFENSIN 2 mRNAEXPRESSION BY MYCOBACTERIUM TUBERCULOSIS IN A HUMAN LUNG EPITHELIAL CELLLINE. SOP19. B Ortiz et al. (Colombia). ROLE OF CD14, MANNOSE RECEPTOR (MMR), SCAVENGERRECEPTOR (ScR) AND TOLL-LIKE RECEPTOR 2 (TLR2) IN Mycobacterium tuberculosis-INDUCED MACROPHAGE APOPTOSIS. SOP20. AVE Capozzo et al. (Argentina) DEVELOPMENT OF GENETIC VACCINES AGAINST HEMOLYTIC

UREMIC SYNDROME (HUS). SOP21. Sandra Bajaña-Miranda et al. (Mexico). CUTANEOUS LANGERHANS DENDRITIC CELLS AND gdT CELLS IN A MURINE MODEL OF LEPROSY: IN VIVO ANALYSIS. SOP22. RM Salazar González et al. (Mexico). EVALUATION OF THE IMMUNE RESPONSE TO PORINSFROM Salmonella typhi IN HUMANS. PHASE 1 STUDY. VACCINE AGAINST TYPHOID FEVER.SOP23. M Lastre et al. (Cuba-Italy). NEUTROPHILS IN THE INDUCTION OF IMMUNE RESPONSE ANDEFFECTOR CELA MENINGITIDIS B. SOPADJUVANTS1. Johan Hoebeke (France) What can we learn from the structure of antibody-peptide complexes?2. Wolfram Metzger (Germany) Attenuated Salmonella as carriers for an anti Helicobacter vaccinein mouse and man3. José A López (Australia) Optimising a blood DC preparation for immunotherapy4. Gerardo E Guillén (Cuba) Immunologic evaluation of a DTP-HB vaccine formulation for nasaladministration5. Jim Koropatnick (Canada) Metallothionein and innate activation of primary human and mousemonocytes6. Osmir Cabrera (Cuba) Conjugation as a possible solution to antigens with low immunogenicityIMMUNODEFICIENCIES1. Harmut Peter (Germany) Common variable immunodeficiency: a new classification andmolecular definition of new subsets2. Teresa Español (Spain) Diagnosis of the molecular defects causing primary immunodeficiencydiseases3. Ricardo Sorensen (Argentina) Specific antibody deficiencies: implications for the developmentof the humoral immune system4. Oscar Porras (Costa Rica) MHC class II deficiency5. Julia Palma (Chile) Pediatric Hematopoyetic Stem Cell Transplantation (HSCT) in primaryimmunodeficiency diseases6. Teresa Español (Spain) Update on therapy for primary immunodeficiency diseasesIMMUNOLOGY AND REPRODUCTION1. Petra Clara Arck (Germany) Immunobiology of implantation and occult pregnancy loss2. Ricardo A. Margni (Argentina) Asymmetric antibodies: role in the maintenance of a nonconflictivemother-fetus relation3. Gerard Chaouat (France) Cytokines in pregnancy and implantation/early abortion: re-examiningthe Th1/Th2 paradigm4. Ana Claudia Zenclussen (Argentina) Introducing a novel mouse model for pre-eclampsia5. Li via Lustig (Argentina) Immunoregulation and autoimmunity of the testis: pathogenesis ofexperimental autoimmune orchitis6. J Puente et al. (Chile) FUNCTIONAL AND PHENOTYPIC RESPONSE OF THE HUMAN NK CELLSIN NORMAL AND PATHOLOGICAL PREGNANCY. SOPAUTOIMMUNITY AND AUTOIMMUNE DISEASES1. Jorge Kalil (Brazil) Antigen recognition and trimolecular complex in post-infectious autoimmunedisease2. Eli Sercarz (USA) Public, drived T cell clones as the cause of autoimmunity in EAE and IDDM3. Xian-hao Xu (China) Recent advances of study on Myasthenia Gravis in China4. Ethel García Latorre (Mexico) Process and presentation of the rHSP60 from Klebsiellapneumoniae in ankylosing spondylitis

5. Johan Hoebecke (France) Autoantibodies against G protein coupled cardiovascular receptors:how do they interfere with receptor function?6. F Zambrano-Zaragoza et al. (Mexico) RECOGNITION OF THE 117-125 PEPTIDE OF THE HSP60FROM Klebsiella pneumoniae BY CD8 T CELLS FROM ANKYLOSING SPONDYLITIS PATIENTS.SOP7. F González et al. (Chile) THE -308 POLYMORPHISM IN THE PROMOTER REGION OF TUMORNECROSIS FACTOR GENE AND EX VIVO LIPOPOLYSACCHARIDE-INDUCED TNF EXPRESSIONIN PATIENTS WITH AGGRESSIVE PERIODONTITIS AND/OR TYPE 1 DIABETES MELLITUS. SOP8. Moncef Zouali (France) Immune receptor signaling and autoimmunity9. Enrique Montero (Cuba) Therapeutic immunosuppression and immunodiagnosis of autoimmunediseases based on an anti-CD6 monoclonal antibody10. Nikolai Petrovsky (Australia) Pathogenesis of type 1 diabetes: dominant pathway of beta cellapoptosis and prevention of immune mediated beta cell destruction11. Clelia M. Riera (Argentina) Experimental autoimmune prostatitis: a model of chronic nonbacterium human prostatitis?12. Constantin Bona (USA) Molecular and genetic studies on the role of IL-4 in fibrosis13. X Hernández et al. (Cuba) EVALUATION OF THE TOXICITY OF THE HUMANIZEDMONOCLONAL ANTIBODY T1HT IN PATIENTS WITH RHEUMATOID ARTHRITIS. SOP14. M Sospedra et al. (Spain-USA) UNBIASED IDENTIFICATION OF ANTIGEN SPECIFICITIES OFCEREBROSPINAL FLUID-INFIL MULTIPLE SCLEROSIS. SOPSIGNAL TRANSDUCTION - CELL INTERACTIONS1. Hannes Stockinger (Austria) Membrane microdomains in signal transduction of immune cells2. Mario Rosemblatt (Chile) Dendritic cells as regulators of lymphocyte homing3. Henry Metzger (USA) Quantitative analysis of signal transduction4. Leopoldo Santos (Mexico) CD38 uses the classical signal transduction pathway PLC-gamma 2,pKC, and nF-kB to induce survival and proliferation of mature B cells5. John Kappler (USA) The role of Bcl-2 related proteins in T-cell death6. Carlos Rosales (Mexico) PI 3-K and ERK are recruited for Fc receptor-mediated phagocytosisduring monocyte-to-macrophage differentiation.ANTIGEN PRESENTATION - TRANSPLANTATION1. Laurence Boumsell (France) International workshops and conferences on CD molecules: past,present, and future2. Nelson Fernández (UK) Models of cell surface expression of MHC Class II and its importance inthe immunological synapse3. Cristina Cuturi (France) Regulatory cells and tolerance in transplantation4. Ignacio Anegón (France) Costimulatory blockade and tolerance in allotransplantation using genetransfer5. Josef Brock (Germany) Alloreactive EGFP-engineered T lymphocytes in a rat kidneytransplantation model6. D Sauma et al. (Chile) THE DECREASE ON T CELL COUNTS AFTER A SINGLE DOSE OFIMMUNOSUPPRESSIVE DRUGS IN RENAL TRANSPLANT PATIENTS CAN BE ASCRIBED TO ALOW DOSE OF PREDNISONE. SOPIMMUNOLOGY OF ALLERGIC DISEASES1. Rudolf Valenta (Austria) Recombinant allergen-based strategies for diagnosis and therapy ofIgE-mediated allergies

2. Momtchilo Russo (Brazil) Oral tolerance prevents the development of airway hyperactivity andTh2-associated allergic responses in prototypic murine models of experimental asthma3. Ruben Rodriguez-Gavalda (Cuba) Natural history, treatment, and management of childhoodasthma4. Alina Alerm (Cuba) Immune response against vaccine antigens in asthmatic patients5. Sabine Flicker (Austria). A grass polen allergen-specific human IgE antibody recognizingimmunoglobulin-like domains6. Alexis Labrada (Cuba-Colombia) Characterization of rBlo t 13, recombinant allergen from Blomiatropicalis using monoclonal antibodies.7. TG Naidu et al. (Brazil) A COMPARATIVE EVALUATION OF SERUM EOSINOPHIL CATIONICPROTEIN (S-ECP) AND TOTAL BLOOD IgE AS DIAGNOSTIC PARAMETERS IN PEDIATRICASTHMA. SOP8. L. Calderón et al. (Cuba) LIPOSOME ENCAPSULATION OF THE MAJOR ALLERGENS OFDermatophagoides siboney FOR SPECIFIC IMMUNOTHERAPY. SOP9. JL Aguilar Olano et al. (Peru). ETIOPATHOGENIC ROLE OF FUME OF FISH'S FLOURFACTORIES IN THE DEVELOPMENT OF ALERGIC MANIFESTATIONS BY CHILDRENACHANCAY, LIMA, PERU. SOPIMMUMUNOTECHNOLOGY1. Luis Javier González (Cuba) Advances in proteome technology2. James W. Larrick (USA) New approaches for design of gene chips3. Angel Oñate (Chile) DNA vaccine in Brucella abortus4. Alexei Licea (Mexico) Anti-idiotypic chimeric antibodies as an anti-scorpion toxin vaccine5. Alexei Licea (Mexico) Shark chimeric antibodies6. Cristina Mateo (Cuba) A new method to reduce immunogenicity of chimeric monoclonalantibodies7. Gertrudis Rojas (Cuba) Phage display libraries as sources of human antibodies: from basics toclinics8. Gregg Silverman (USA) Phage-display engineering of magic bullets for induction of in vivo VHtargeted apoptotic deletion of B-cells in mice and non human primates9. James W. Larrick (USA) Taczyme: a new means to generate and affinity mature antibodies10. Merardo Pujol (Cuba) Tobacco as a model plant for recombinant antibody expression11. Rodolfo Valdés et al. (Cuba) IMMUNOPURIFICATION OF THE HEPATITIS B SURFACE ANTIGENUSING A PLANT-DERIVED HBsAg-SPECIFIC ANTIBODY. SOP12. O Gires et al. (Germany) DIRECT IDENTIFICATION OF TUMOR ANTIGENS BY AUTOLOGOUSANTIBODY SCREENING. SOP13. P Vargas et al. (Chile) DENDRITIC CELL IMMUNIZATION IMPROVES PRODUCTION OFMONOCLONAL ANTIBODIES AGAINST THE REGULATOR OF MHC CLASS II EXPRESSION(CIITA). SOPCYTOKINES - INFLAMATION1. Juan C. Aguillón (Chile) Genetic polymorphism of cytokines: implications on susceptibility orresistance to diseases2. Sergio Romagnani (Italy) Pleiomorphic role of CXCR3 and its ligands3. Ralf Schumann (Germany) Pathogen-associated molecular patterns (PAMPs) and the host'sinnate immune recognition system4. Douglas Golenbock (USA) Lessons from Drosophila: the LPS receptor5. Manuel Araña (Cuba) Anti LPS peptides and cytokine regulation in sepsis6. Horacio Serra (Argentina) SLC (CCL21): much more than a constitutive chemokine7. M Kurte et al. (Chile) A SYNTHETIC PEPTIDE HOMOLOGOUS TO THE FUNCTIONAL DOMAINOF HUMAN INTERLEUKIN 10 DOWNREGULATES THE EXPRESSION OF THE MHC CLASS I

ALPHA CHAIN AND TAP 1/2 IN HUMAN MELANOMA CELLS. SOP8. John Hiscott (Canada) IFN and NF-kB signaling pathways and the regulation of innate immunity9. Silvio Perea (Cuba) Abrogation of the interferon (IFN) signaling pathways by humanpapillomavirus (HPV) type-1610. Celia Fernandez (Cuba) NF-kB down regulation is a common target for the inhibition of TNFproduction and HIV replication by the DLE11. Pedro Porrero (Cuba) Interferon-alpha in nervous system disorders12. P A Rojas et al. (Peru-Germany) EFFECT OF AN EXTRACT OF Uncaria tomentosa (UÑA DEGATO) ON THE PRODUCTION OF THE TUMORAL NECROSIS FACTOR - ALPHA IN A MODELIN VIVO AND ITS ACTION LIKE AN ANTI-INFLAMMATORY AGENT IN VITRO. SOPIMMUNODIAGNOSTICS1. Rene Robaina (Cuba) Creating a sustainable diagnostic network with national scope: the caseof the SUMA system in Cuba2. Luis Sorell (Cuba) Immunodiagnosis of celiac disease using fast visual tests3. Mercedes Lopez (Chile) Immunohistochemical diagnosis of uveal malignant melanoma usingMelanocortin 1 Receptor (MC1R) specific antibodies4. Anselmo Otero (Cuba) Immunoanalytic tools for the evaluation of enzymatic function. AcatELISA for detection of HIV protease inhibitors.5. B Velázquez et al. (Uruguay) OPTIMIZATION OF RECOMBINANT STREPTOLYSIN-OEXPRESSION AND ANALYSIS OF FINAL PRODUCT FORMULATIONS SUITABLE FORIMMUNODIAGNOSIS. SOP6. M Hernández et al. (Cuba) CHIMERIC SYNTHETIC PEPTIDES CONTAINING TWOIMMUNODOMINANT EPITOPES FROM THE GAG P19 PROTEIN AND THE ENVELOPE GP46GLYCOPROTEIN FOR THE IMMUNODIAGNOSIS OF HTLV-II VIRUS INFECTION. SOP7. RA Rivero et al. (Cuba) MOUSE MONOCLONAL ANTIBODIES AGAINST ABO BLOOD GROUPANTIGENS IN CUBA: ITS EVALUATION IN THE 4TH INTERNATIONAL WORKSHOP. SOP8. C Macías et al. (Cuba) ENDOTHELIAL ADHESION MOLECULES ICAM-1, VCAM-1 AND E-SELECTIN IN PATIENTS WITH ACUTE CORONARY SYNDROME. SOPVETERINARY IMMUNOLOGY1. Manuel Rodriguez (Cuba) The Cuban experience in the control of Boophilus spp. by the anti-tickvaccine GavacTM2. Patricia Zamorano (Argentina) Bovine herpes virus protein from plants infected withrecombinant tobacco mosaic virus possesses authentic antigenicity3. A Soutullo et al. (Argentina) IMMUNE RESPONSE OF THE EQUINE INFECTIOUS ANEMIADISEASE VIRAL GP 45 PROTEIN TO A SYNTHETIC PEPTIDE IN MICE. SOP4. TA. Cruz (Mexico) APOPTOSIS IN LUNGS OF PIGS INTRATRACHEALLY INOCULATED withMycoplasma hyopneumoniae. SOP5. J. Casas et al. (Mexico) COMPARATIVE STUDY OF THE IMMUNE RESPONSE OF FIVEDIFFERENT SPECIES OF TILAPIA (Oreochromis). SOP6. R Rivers et al. (Chile) DNA VECTORS FOR Brucella abortus. SOP7. TG Naidu. (Brazil) LYSOSOMAL DEGRANULATION IN POLYMORPHONUCLEAR NEUTROPHILS:A NOVEL MECHANISM OF SURVIVAL OF PATHOGENIC b-HEMOLYTIC Staphylococcus aureusIN THE BOVINE MAMMARY GLAND. SOP8. AP West Jr, PJ Bjorkman. (USA) CLONING AND CHARACTERIZATION OF THE CHICKEN YOLKSAC IGY RECEPTOR. SOP

POSTER SESSIONSIMMUNOLOGY OF BACTERIAL DISEASES I1. HLA CLASS II GENES POLIMORPHISMS IN DRUG SENSITIVE AND DRUG RESISTANTPULMONARY TUBERCULOSIS IN MEXICANS PATIENTS. A Camarena Olvera, A JuárezCisneros, A Aquino Gálvez, D Castillo Sánchez, R Falfán Valencia. (MEXICO).ang_edco@yahoo.com.mx.2. DEVELOPMENT OF GENETIC VACCINES AGAINST HEMOLYTIC UREMIC SYNDROME (HUS).2 AVE Capozzo, C Ibarra, V Pistone Creydt, G Dran, G Fernández, M Isturiz, MS Palermo.(ARGENTINA). alejavicca@yahoo.com.ar3. TNFa, IFNg AND IL-10 GENE POLYMORPHISMS AND CYTOKINE PRODUCCION IN PATIENTS3 WITH TUBERCULOSIS (TB) AND HEALTHY CONTROLS. M Henao, S París, L F García.(COLOMBIA) marcelaisabel@yahoo.com4. HIGH LEVELS OF NITRIC OXIDE CORRELATES WITH MYCOBACTERIUM TUBERCULOSIS4 INHIBITION OF IFNg-INDUCED MHC CLASS II EXPRESION IN MURINE MACROPHAGES. JLJaramillo, GM Vásquez, LF García, LF Barrera. (COLOMBIA). fbarrera@quimbaya.udea.edu.co5. EXPRESSION OF TOLL-LIKE RECEPTOR 2 (TLR2) IN DIFFERENT CIRCULATING CELLPOPULATIONS AND COMPARISON OF CD14+TLR2+ BLOOD MONOCYTES IN PATIENTS5WITH TUBERCULOSIS AND HEALTHY CONTROLS. MC Ruiz, M Rojas, LF García. (COLOMBIA).rrcaro@epm.net.co6. MONOCYTES AND NEUTROPHILS FROM TUBERCULOSIS PATIENTS ARE INSENSITIVE TOANTI-INFLAMMATORY EFFECTS TRIGGERED BY A PROTOTYPIC N-FORMYL PEPTIDE (FMLP).6M Beigier-Bompadre, M Alemán, P Barrionuevo, MC Franco, CJ Rubel, MS Palermo, E Abbate,MC Sasiain, MA Isturiz. (ARGENTINA). mbeigier@yahoo.com7. ROLE OF POLYMORPHISMS OF THE CD14 GENE PROMOTER IN TUBERCULOSIS. C Fonseca, E7Pacheco, L Garcia, M Arias. (COLOMBIA) marias@medicina.udea.edu.co8. MODULATION OF SCAVENGER RECEPTORS (ScR) IN MONOCYTES FROM HEALTHY8 CONTROLS AND PATIENTS WITH TUBERCULOSIS (TB) BY MYCOBACTERIAL DERIVATIVES.LG León, M Rojas, LF García. (COLOMBIA) mrojasl@epm.net.co9. BYSTANDER MACROPHAGES REMOVE Mycobacterium tuberculosis-INFECTED9 MACROPHAGES AND INHIBIT THE INTRACELLULAR GROWTH OF Mycobacteriumtuberculosis. LG León, M Rojas, LF García. (COLOMBIA) mrojasl@epm.net.co10. ROLE OF CD14, MANNOSE RECEPTOR (MMR), SCAVENGER RECEPTOR (ScR) AND TOLL-LIKERECEPTOR 2 (TLR2) IN Mycobacterium tuberculosis-INDUCED MACROPHAGE APOPTOSIS. B0Ortiz, M Rojas, LF García. (COLOMBIA) mrojasl@epm.net.co11. SPECIFIC PROLIFERATION OF CD4+ AND CD8+ T CELLS AGAINST Brucella abortus RB51ANTIGEN. M C Moreno-Lafont, V Paredes-Cervantes, A Estrada-Aguilera, R López-Santiago.(MEXICO). mlafont@encb.ipn.mx12. EPIDEMIOLOGY OF MUCOCUTANEOUS INFECTIONS IN THE RECURRENT INFECTIONSYNDROME. JC Orrego, CJ Montoya, RD Gómez, PJ Patiño G., ME Vargas, JL Franco R., D2García de O., JC Wolf. (COLOMBIA)13. MrpA FIMBRIAL PROTEIN AS A PROTECTIVE ANTIGEN AGAINST URINARY TRACTINFECTIONS. R Pellegrino, P Scavone, U Galvalisi,V Sosa, L Geymonat, P Zunino. (URUGUAY).3rafael@iibce.edu.uy14. MODULATION OF MYCOBACTERIAL-INDUCED MACROPHAGE APOPTOSIS BY ANTI-4 MYCOBACTERIAL DRUGS. D Gil, LF García, M. Rojas. (COLOMBIA). mrojasl@epm.net.co PDF15. MYCOBACTERIAL-INDUCED NECROSIS AND APOPTOSIS IN MACROPHAGES FROMPATIENTS WITH TUBERCULOSIS (TB) AND HEALTHY CONTROLS DEPEND ON TNF-alfa/IL-105BALANCE. D Gil, LG León, LF García, M Rojas. (COLOMBIA). dipagil@medicina.udea.edu.co

16. EVALUATION OF THE IMMUNE RESPONSE TO PORINS FROM Salmonella typhi IN HUMANS.PHASE 1 STUDY. VACCINE AGAINST TYPHOID FEVER. RM Salazar González, MC Maldonado6 Bernal, NE Ramirez, J Beltrán Nava, C Tello Winniczuk, M Carrera Camargo, C López Macias, AIsibasi. (MEXICO). rsalg@yahoo.com17. SALIVARY LEVELS OF IgA AND Streptococcus mutans IN PRE-AMAZONIC BRAZILIANPREGNANT WOMEN. R R Maya, M V V Lima, J E Batista , R N M Guerra. (BRAZIL/BRASIL).7rguerra@elo.com.br18. OPTIMIZATION OF PRECLINICAL IMMUNIZATION WITH OUTER MEMBRANE VESICLESVACCINE. G Bracho, S Cabezas, J del Campo, M Lastre, T Rodríguez, C Zayas, G Sierra, O8Pérez. (CUBA). gbracho@finlay.edu.cu19. ENDOGENOUS GLUCOCORTICOID (GC) MODULATE NEUTROPHIL (PMN) FUNCTION IN AMURINE MODEL OF HEMOLYTIC UREMIC SYNDROME (HUS). S Gómez, G Fernández , C9 Rubel, F Alves Rosa, P Barrionuevo, MA Isturiz, MS Palermo. (ARGENTINA).gomezs1015@yahoo.com.ar20. NEUTROPHILS IN THE INDUCTION OF IMMUNE RESPONSE AND EFFECTOR CELL AGAINST2NEISSERIA MENINGITIDIS B. M Lastre, J Lapinet, G Bracho, C Zayas, M Díaz, G Sierra, MA0Cassatella, and O Pérez. (CUBA-ITALY) mlastre@finlay.edu.cu21. CROSS-REACTIVE ACTIVITY OF ANTIMENINGOCOCCAL HUMAN IMMUNOGLOBULIN2AGAINST DIFFERENT NEISSERIA MENINGITIDES GROUP B SEROTYPES. BalboaJA, et al.(Cuba). jbalboa@finlay.edu.cu22. MYCOBACTERIAL ACYL-O-TREHALOSES MODULATE HUMAN T-CELL RESPONSES IN VITRO.2R Saavedra, P Lezama, R Leyva, E Segura, LM López Marín. (MEXICO).2saavedra@servidor.unam.mx23. EFFECT OF THE SPLENIC DIALIZABLE EXTRACT (SDE) ON MURINE EXPERIMENTAL2 TUBERCULOSIS, ASSESSED BY DIFFERENTIAL DISPLAY. M Pérez-Tapia, R Ramos-Payán, A3 Fabre-Ruíz, J Rangel-Moreno, R Hernández-Pando, I Estrada-G, S Estrada-Parra S. (MEXICO).maypet@hotmail.com24. CD28, CD80 AND CD86 EXPRESSION IN SKIN CELLS OF LEPROMATOUS AND TUBERCULOID2LEPROSY PATIENTS. S Navarro, C Guerrero, M Corrales, R López, M Fafutis. (MEXICO).4celiagv2001@yahoo.com.mx25. INDUCTION OF HUMAN b-DEFENSIN 2 mRNA EXPRESSION BY MYCOBACTERIUM2TUBERCULOSIS IN A HUMAN LUNG EPITHELIAL CELL LINE. B Rivas-Santiago, C Sarabia, S5Schwander, G Diamond, E Sada. (MEXICO-USA/MEXICO-EEUU). rondo_vm@yahoo.com26. CD8+ T CELLS IMPROVE GROWTH INHIBITION OF MYCOBACTERIUM TUBERCULOSIS (MTB)2 H37RV IN HUMAN ALVEOLAR MACROPHAGES INFECTED IN VITRO. C Carranza, E Juárez, R6 Hernández, C. Sarabia, K Bobadilla, D Escobedo, J Ellner, E Sada, S Schwander. (MEXICO-USA/MEXICO-EEUU). carranza_1999@yahoo.com27. MEMORY ANTIBODY RESPONSE AND BACTERICIDAL ACTIVITY INDUCED BY PORINS FROM2Salmonella enterica SEROVAR Typhi. I Secundino, L Cervantes, J Beltran, R Salazar, C7Maldonado, A Isibasi, C López-Macias. (MEXICO). isibasi@prodigy.net.mx28. DIFFERENTIAL PATTERN OF MITOCHONDRIAL MEMBRANE POTENTIAL (DYm) And2 CYTOSOLIC CYTOCHROME C In M. tuberculosis H37Ra- AND H37Rv-INFECTED8 MACROPHAGES. E Abarca-Rojano, P. Rosas-Medina, P Zamudio-Cortéz , R Mondragón-Flores,FJ Sánchez-García. (MEXICO). fsanchez@bios.encb.ipn.mx29. CELL SIGNALING OF MYCOBACTERIAL-INDUCED MACROPHAGE APOPTOSIS. M Rojas, LF9 García, M Olivier, B Ortiz, D Gil, LG León. (COLOMBIA-CANADA). mrojasl@epm.net.co30. M. tuberculosis CULTURE FILTRATE PROTEINS INDUCE CD95 RELATED APOPTOSIS ON3MONOCYTES OF THE THP-1 LINE. R. Mancilla, G. Bernal, P. Espinosa-Cueto, H. Díaz-Silvestre,0M.A. Esparza-Cerón, M. Colón-González. (MEXICO) mancilla@servidor.unam.mx31. THE 19 kDa GLYCOLIPOPROTEIN OF Mycobacterium tuberculosis IS A MAJOR ADHESIN FOR3THP-1 AND MONOCYTE DERIVED-HUMAN MACROPHAGES. H. Díaz-Silvestre, P. Espinosa-Cueto, G. Bernal, C. Espitia, and R. Mancilla. (MEXICO) hugo@biomedicas.unam.mx

32. EFFECTS OF MYCOBACTERIAL LIPIDS ON PLEURAL MONONUCLEAR CELLS AND OF3PETIVERIA ALLIACEA EXTRACT ON RESPONSE TO BCG IN THE PLEURAL CAVITY. V Cabral,2A Rodrigues, E Abi-chacra, E Rodrigues, A Moura. (BRAZIL). cmoura@uerj.br33. T-CELL PROLIFERATION AND IL-2 LEVELS IN YOUNG HEALTHY HOUSEHOLD CONTACTS OF3LEPROMATOUS LEPROSY PATIENTS. M. Pita, A. Santerre, G. Zaitseva, A. Islas. (MEXICO).3mpita@cucba.udg.mx34. THE AP-1 TRANSCRIPTION FACTOR IS PRESENT IN LYMPHOCYTES FROM LL PATIENTS. Ma.4 R. Huizar, A. Santerre, V. Madrid , O. Peralta , A.E. Islas. (MEXICO). mhuizarl@yahoo.com.mx35. MEMORY RESPONSE GENERATED IN AFRICAN GREEN MONKEYS AGAINST3POLYSACCHARIDE C CONJUGATE. Carmenate T, Guirola M, Álvarez A, Caballero E, González5S, Menéndez T, Canaán-Haden L, Guillen G. (CUBA). Anabel.alvarez@cigb.edu.cu36. COMPARISON OF THE IMMUNE RESPONSE IN MICE AGAINST MENINGOCOCCAL GROUP C3 POLYSACCHARIDES CONJUGATE TO THREE CARRIER PROTEINS. Alvarez A, Canaan-Haden6 L, Carmenate T, Menendez T, Delgado D, Rodes L, Silva R, Guillén G. (CUBA).Anabel.alvarez@cigb.edu.cu37. IMMUNOGENICITY AND PROTECTIVE CAPACITY OF LEPTOSPIRA INTERROGANS3 SEROGROUP BALLUM KILLED WHOLE CELL ADJUVANTED VACCINES IN HAMSTERS. A7 González, Y Rodríguez, Y Valdés, N Batista, JF. Nuñez, JF. Infante, M González. (CUBA).andresglez@finlay.edu.cu38. IMMUNOGLOBULIN PREPARATION AGAINST LPS OF PSEUDOMONAS AERUGINOSA3SEROTYPE O11. A Moya, L Joó, A Rodrígruez, J Hernández Machín, J Hernández, JF8Almenares, D Berrios, Z Rodríguez, A Cádiz, SC Esnard. (CUBA). amoya@finlay.edu.cu39. EVALUATION OF THE SPECIFIC HUMORAL IMMUNE RESPONSE IN MICE IMMUNIZED WITH3 AN EXPRESSION GENOMIC LIBRARY OF MYCOBACTERIUM TUBERCULOSIS. A Acosta, Z9 Díaz, K Hernández, ME Sarmiento, JL Leiva, M Martínez, M Fariñas, JF Infante , G Sierra .(CUBA). aracosta@finlay.edu.cu40. EVALUATION OF THE EFFECT OF THE ADMINISTRATION OF HUMAN GAMMAGLOBULINS IN4 A MODEL OF INFECTION WITH BCG IN MICE. A Acosta, N Olivares, A León, Y López, ME0 Sarmiento, A Cádiz, A Moya, G Falero, JF Infante, M Martínez , G Sierra . (CUBA).aracosta@finlay.edu.cu41. THE VIABILITY AND THE COLONIZATION CAPACITY OF VACCINAL FORMULATION OF4ATTENUATED STRAIN 638 (VIBRIO CHOLERAE ). A Talavera, T Moreira, G Año, B Cedré, HDelgado, H García, L García. (CUBA). atalavera@finlay.edu.cu42. ANTIGENICITY AND IMMUNOGENICITY OF INACTIVATED Vibrio cholerae STRAIN. G Año, H4García, T Valmaseda, B Cedré, Y Pino, O Ancheta, JL Pérez, L García, A Talavera. (CUBA).2gano@finlay.edu.cu43. PURIFICATION AND CHARACTERIZATION OF LIPOPOLYSACCHARIDE OF DIFFERENTSEROTYPES FROM PSEUDOMONAS AERUGINOSA. CLINICAL APPLICATIONS. Jonatan4Hernandez, Sara C. Esnard, Aniel Moya, Hilda García, Barbará Cedré, Juan Almenares, Ana3Callis, Vismak Torres, Jacqueline Alonso, Armando Cadiz, Gustavo Sierra.(CUBA).jhernandez@finlay.edu.cu44. SAFETY AND IMMUNOGENICITY OF A SINGLE DOSE OF LIVE ATTENUATED ORAL CHOLERA4 VACCINE STRAIN 638, IN ECUADOR. H García, J Menéndez, L Shinkarenko, L E Plaza, L4 Izquierdo, Barbara Cedré, Tania Valmaseda, Y Pino, J L Pérez, G Año, L García, R Fando, ATalavera, G Sierra (CUBA). hgarcia@finlay.edu.cu45. INHIBITION OF ANTICOLONIZING EFFECT OF POSITIVE SERUM FROM HUMANS INOCULATED4WITH THE ATTENUATED STRAIN 638 VIBRIO CHOLERAE O1. JL. Pérez, Y Pino, T Valmaseda,5G Año, B Cedré, H García, A Talavera, L García. (CUBA).46. PERSISTENCE OF TETANUS AND DIPHTHERIA ANTITOXIN IN CUBAN PRESCHOOL CHILDREN.46Martínez JC, Ochoa RF, Ferriol XR, Estrada EA, Sotolongo FT. (CUBA).jcmartinez@finlay.edu.cu

47. TETANUS AND DIPHTHERIA ANTITOXIN LEVELS IN NEWBORNS FROM HAVANA CITY.4Martínez JC, Ochoa RF, Ferriol XR, Estrada EA, Sotolongo FT. (CUBA).7jcmartinez@finlay.edu.cu48. A PRELIMINARY EVALUATION OF THE PROTECTIVE CAPACITY OF A PREPARATION OF4 IMMUNOGLOBULINS ANTI LYPOPOLISACCHARIDES OF Pseudomonas aeruginosa SEROTYPE8 O11. J Almenares, S Sifontes, J Cobián, A Moya, A Cádiz, D Díaz, M Camacho. (CUBA).almenare@yahoo.es and juan@cebi.uo.edu.cu49. EXPERIENCE ON THE DEVELOPMENT OF BIOMODELS FOR HAEMOPHILUS INFLUENZAE TYPE9 B INFECTION. JF Infante, S Sifontes. (CUBA). jinfante@finlay.edu.cu50. BEHAVIOUR OF THE INMUNOLOGICAL PARAMETERS IN PATIENTS WITH PIODERMITIS. L.0 Sánchez, I. Martén, E. Lay, X. Rodriguez . (CUBA). Isabel@hospclin.scu.sld.cu51. EVALUATION OF THE IMMUNE HUMORAL RESPONSE AGAINST B AND C SEROGROUPS OF5NEISSERIA MENINGITIDIS IN INFANTS VACCINATED WITH VA-MENGOC-BC. L A. PeláezYañez, E. Estrada, R. Ochoa. (CUBA). ochoa@finlay.edu.cu52. MOUSE MONOCLONAL ANTIBODIES AGAINST OUTER MEMBRANE PROTEINS OF THE CUBAN5VACCINE STRAIN OF NEISSERIA MENINGITIDIS B:4:P1.19.15. M. E. Pérez, Barbera R., Otero2O, Gutiérrez M., Domínguez F, Vidal T, Sierra G, Campa. C. (CUBA). meperez@finlay.edu.cu53. STUDY OF THE PROTECTIVE CAPABILITY IN MICE OF THE STRAIN SALMONELLA TYPHI TY521ª EXPRESSING THE B SUBUNIT OF CHOLERA TOXIN (CTB). ME Sarmiento, I Feria, L3Riverón, A Acosta, M Fariñas, JF Infante, G Sierra. (CUBA). aracosta@finlay.edu.cu54. STUDY OF THE EXPRESSION OF THE B SUBUNIT OF CHOLERA TOXIN IN DIFFERENT LIVE5ATTENUATED VECTORS. ME Sarmiento, A Acosta , J Díaz , M Martínez, P Estévez , G Sierra.4(CUBA). aracosta@finlay.edu.cu55. EXPERIMENTAL MURINE CRYPTOCOCCOSIS. Odalis Asín Milán, Gerardo Martínez Machín,5 Maria Teresa Ilnaitt, Ileana Valdez. (CUBA). oasin@ipk.sld.cu56. CHARACTERIZATION OF SHIGELLA FLEXNERI STRAINS: SEROTYPE CORRELATION,5ANTIMICROBIAL SUSCEPTIBILITY AND PLASMÍD PROFILE. Roberto Cabrera , Margarita6Ramírez , Laura Bravo, Anabel Fernández, Nelsideismy Castañeda. (CUBA). roberto@ipk.sld.cu57. CARACTERIZATION OF THE IMMUNE RESPONSE OF A VACCINE PREPARATION AGAINST5 THE Haemophilus influenzae TYPE B IN RABBIT SERA. V Vérez, V Fernández, A Rodríguez-7 Silva, F Cardoso, M Izquierdo, A Mussachio, Y Valdés, MC Rodríguez, L Heynngnezz, J Chang,E Hardy (CUBA). arlene.rodriguez@cigb.edu.cu58. PRODUCTION AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES AGAINST THE5 TOXIN CO-REGULATED PILUS OF VIBRIO CHOLERAE. G. Falero, BL. Rodriguez, I. Rodríguez, J.8 Campos, T. Ledon, E. Valle, Y. Silva, K. Marrero, T. Valmaseda, A. Moreno, R. Fando (CUBA).boris@biocnic.cneuro.edu.cu59. GENERAL CHARACTERISTICS OF RECOMBINANT MOREAU BCG STRAIN CARRYING 5C5PROTEIN Neisseria meningitidis GENE. I. Griñán; T. Vidal; V. Pasos; C. Campa; G. Sierra, A.9Acosta; ME. Sarmiento; JF. Infante. (CUBA)60. RECENT ADVANCES IN THE STUDY OF DCTXPHI, HAP::CELA LIVE CHOLERA VACCINECANDIDATES IN VOLUNTEERS. Rafael Fando, Luis García, Arturo Talavera, Hilda García,6Bárbara Cedré, Javier Campos, Boris L. Rodríguez, José L. Pérez, Tania Valmaseda, Oliver0Pérez, Alberto Pérez, Margarita Ramírez, Laura Bravo, Irma González, Talena Ledón, ManuelDíaz Jidy, Miriam Lastre. (CUBA) fando@biocnic.cneuro.edu.cu61. CONTRIBUTION TO THE STUDY OF THE INFANT CRIPTOCOCOSIS IN CUBA. Rosaura F.Escobar Aragón. (CUBA). rossy@infomed.sld.cu62. EXPRESSION OF TCP AND MSHA MAJOR PROTEINS FROM VIBRIO CHOLERAE STRAINS,6 CULTURE IN DIFFERENT CONDITIONS BY USING SPECIFIC MONOCLONAL ANTIBODIES. Y.2 Silva, BL. Rodríguez, J. Campos, T. Ledon, K. Marrero, E. Suzarte, E. Martinez, A. Moreno, G.Falero, I. Rodríguez, R. Fando (CUBA). yussuan@biocnic.cneuro.edu.cu63. EVALUATION OF MUCOSAL IMMUNOGENICITY OF 638 ORAL LIVE ATTENUATED EL TOR3 CANDIDATE VACCINE STRAIN. J del Campo et al. (Cuba) judithc@finlay.edu.cu

64. SEARCHING TARGETS FOR ADJUVANT SCREENING. D. Gil et al. (CUBA)4 inmunobyc@finlay.edu.cu65. PREVALENCE OF HELICOBACTER PYLORI INFECTION AND CHARACTERISTICS OF STRAINS6 IN LA HABANA, CUBA. B. Gutiérrez, C. Camou-Juncas, A. Santos, T. Vidal, C. Valmaña, N.5 González, I. Leonard, R. Martínez, O. Díaz-Canel, M. Paniagua, M.P. Escobar, G. Sierra, G.L.Mendez, Francis Mégraud (CUBA-FRANCE-AUSTRALIA / CUBA-FRANCIA-AUSTRALIA)IMMUNOLOGY OF BACTERIAL DISEASES II1. IMMUNOGENICITY OF SALMONELLA TYPHI VI POLYSACCHARIDE VACCINE IN CUBANSCHOOL CHILDREN. Ochoa Azze RF, Martínez Rodríguez JC, Baró Suárez IM, Ginebra IniestaM, Ferriol Marchena XR, Rodríguez Alfonso VM, Sotolongo Padrón FT, Mirabal Sosa M,Armesto del Río M, Leiva Sánchez TA, Menéndez Hernández J, Domínguez HernándezF.(CUBA). ochoa@finlay.edu.cu2. COMPARISON OF THE IMMUNOGENICITY OF SYNTHETIC LINEAR AND MULTIPLE ANTIGENPEPTIDES CONTAINING A PROTECTIVE EPITOPE DERIVED FROM THE MENINGOCOCCAL2PROTEIN PorA (SUBTYPE 15). S Gonzalez, He Garay, A Cabrales, E Caballero, O Reyes, RPajon. (CUBA). sonia.gonzalez@cigb.edu.cu3. T-CELL RESPONSE AGAINST THE P64k MENINGOCOCCAL PROTEIN IN BALB/C MICE. S3 González, C Nazábal, KVS Rao, O Reyes, HE Garay, Sardiñas G, Caballero E, Silva R. (CUBA-INDIA). sonia.gonzalez@cigb.edu.cu4. SELECTION OF PHAGE-DISPLAYED MIMOTOPE OF NEISSERIA MENINGITIDIS SEROGROUP B4 CAPSULAR POLYSACCHARIDE. Menéndez T, Cruz Y, Coizeau E, Garay H, Carmenate T,Alvarez A, Guillén G.(CUBA). tamara.menendez@cigb.edu.cu5. HELICOBACTER PYLORI INFECTION IN HAVANA, CUBA . PREVALENCE AND CAGE STATUS5 OF THE STRAINS. B. Gutiérrez, C. Camou, A. Santos, T. Vidal, C. Valmaña, N. González, I.Leonard, R. Martínez, O. Díaz-Canel, M .Paniagua, M.P. Escobar, G. Sierra. (CUBA).6. IMMUNOGENICITY AND PROTECTION INDUCED BY THE CUBAN TRIVALENT LEPTOSPIRAL6 VACCINE VAX-SPIRALâ IN RISK POPULATIONS. Y. Rodríguez, M. González, A. González, N.Batista, R. Ochoa, X. Ferriol, M. Baró, M. Armesto.(CUBA). yoandrarod@finlay.edu.cu7. GENERATION OF T CELL LINES AND CLONES FROM A NORMAL DONOR SPECIFIC TO7 Mycobacterium tuberculosis ANTIGENS. Z. Mazorra, G. De Libero. (CUBA-ITALY / CUBA-ITALIA). zaima@ict.cim.sld.cu8. STUDY OF SPECIFIC ANTIBODIES RESPONSE IN FRONT OF THE PROTEIN OF 38 KD OFMYCOBACTERIUM TUBERCULOSIS IN HEALTHY INDIVIDUALS VACCINATED WITH BCG.8 Alina Puig Levy, Herve Bercovier, Yolanta Fishmann, Avi-Chai-Hovav, Yamilé López Hernández,María Elena Sarmiento1, Teresita Vidal Martínez, Rolando Ochoa, Eric Estrada, Gustavo Sierra,Armando Acosta. (CUBA-ISRAEL). alina_puig@finlay.edu.cu9. CUTANEOUS LANGERHANS DENDRITIC CELLS AND gd T CELLS IN A MURINE MODEL OFLEPROSY: IN VIVO ANALYSIS. Sandra Bajaña-Miranda, Adriana Flores-Langarica, Juana9Calderon, Monica Heras-Chavarria, Kendy Wek, Jose Angel Vargas, Oscar Rojas-Espinoza,Leopoldo Flores-Romo. (MEXICO). sbajana@yahoo.es10. RISK FACTORS FOR CARRIAGE OF Neisseria meningitidis IN A PRIMARY SCHOOL INHAVANA. Martínez I, López O, Sotolongo F, Zamora L, Bencomo A, Climent J, Mirabal M.0(CUBA). isamartinez@finlay.edu.cu11. SPECIFIC IgG ANTIBODIES AGAINST LIPOPOLYSACCHARIDE AND ANTI-ENDOTOXICACTIVITY IN ANTIMENINGOCOCCAL HUMAN IMMUNOGLOBULIN. Balboa JA et al. (Cuba).jbalboa@finlay.edu.cu12. ANTIBODY RESPONSES TO MYCOBACTERIUM TUBERCULOSIS AND BCG IN TUBERCULOSISPATIENTS. O Orraca Castillo, A Acosta Domínguez, ME Sarmiento García San Miguel, Y López2 Hernández, DY Díaz Domínguez, M Martínez Benítez, N Olivares Arzuaga, A Puig Levi ARodríguez Rojas(Cuba). odalys@minsap.pri.sld.cu

13. THE ANTI NEISSERIA MENINGITIDES B VACCINE OVERCOME THE THYMUS INDEPENDENCEOF POLYSACCHARIDE C IN TODDLER. O Pérez, M Lastre, G Bracho, J del Campo, T3Rodríguez, C Zayas, C Taboada, G Sierra. (CUBA). oliverp@finlay.edu.cu14. DETECTION OF COMPLEMENT-MEDIATED ANTIBODY-DEPENDENT BACTERICIDAL ACTIVITYIN GROUPS B AND C NEISSERIA MENINGITIDIS COLORIMETRIC SERUM BACTERICIDAL4 ASSAY AND ITS VALIDATION. T Rodríguez, M Lastre, B Cedré, J del Campo, E M Fajardo, MHernández, I Delgado, C Zayas, G Sierra, and O Pérez. (CUBA). trodriguez@finlay.edu.cu15. ANTIBODIES AGAINTS TYPE I HUMAN IMMUNODEFICIENCE VIRUS (VIH) IN PATIENTS WITHTUBERCULOSIS. Zurita Salinas C, Mestanza Peralta M, Coloma NA, Correa M, Cárdenas P.5(ECUADOR) jzurita@hcjb.org.ec16. PHYSICAL-CHEMICAL CHARACTERIZATION BY SDS SOLUBILIZA-TION OF THE OUTERMEMBRANE FROM LEPTOSPIRA POMONA SEROVAR MOZDOK. M Machado Herrera; M6 Naranjo; M Gonzáles; R Medina; E Abreu; J Abreu; N Batista; V Torres; A Gonzáles; J Oramas.(CUBA) mmachado@finlay.edu.cuIMMUNOLOGY OF VIRAL DISEASES1. IMMUNE CELLULAR AND HUMORAL RESPONSE IN DIABETES PATIENTS VACCINATED WITH7 CUBAN ANTI-HEPATITIS B VACCINE. Ariel Jesús Jauma Rojo (Cuba).2. AUTOANTIBODIES DETERMINATION IN PATIENTS WITH MALIGNANT HEMOPATHIES AND8 HEPATITIS C. AM Guerreiro et al. (Cuba) ihidir@hemato.sld.cu3. ESTABLISHMENT OF THE ELISA SYSTEM FOR THE DETECTION OF CAPSIDE ANTIGEN FROMHEPATITIS B VIRUS. M. Peña, Y. Lobaina, Z. Nuñez, Y. Pestana, O. Amarantes. (Cuba)9maxlenin@cigb.edu.cu4. ANALYSIS OF B AND T CELL ACTIVATION IN MESENTERIC LYMPH NODES FROM MICE2INFECTED WITH ROTAVIRUS. E Esquivel, L X-Gutierrez, S Lopez, C Arias, F Esquivel.0(MEXICO). fernando@ibt.unam.mx5. EVALUATION OF IMMUNE RESPONSE OF INFECTED DENGUE PATIENTS TO RECOMBINANT2NS1 AND E PROTEINS. G Mellado Sánchez , L Santos Argumedo, L Cedillo Barrón. (MEXICO).gmellado2001@yahoo.com.mx6. DENGUE VIRUS INFECTION INDUCES AN INCREASE IN THE EXPRESSION OF DEATH22RECEPTOR TNF-R AND ADHESION MOLECULE ICAM-1 AND SUGGESTS APOPTOSIS OFMICROVASCULAR ENDOTHELIAL CELLS (HMEC-1). S Fonseca-Coronado, L Santos-Argumedo,L Cedillo-Barrón (MEXICO). sfonseca@encb.ipn.mx7. GENE EXPRESSION IN HUMAN MACROPHAGES INFECTED WITH DENGUE VIRUS. MMB2Moreno-Altamirano, M Romano, M Legorreta-Herrera, FJ Sánchez-García, MJ Colston.3(MEXICO). bertha@lambda.gene.cinvestav.mx28. HIV RNA LEVEL IN CUBAN PATIENTS. A González, A Alvarez, S Palma (CUBA).4 aileen@ipk.sld.cu9. NEUROIMMUNE EPIDEMIOLOGICAL VALUE OF REIBERGRAM IN THE FIRST ECHOVIRUS 1625MENINGOENCEPHALITIS OUTBREAK IN CUBA. AJ Dorta-Contreras, H Reiber, ME Magraner-Tarrau, B Weissbrick, MT Interián-Morales, E Noris-García, X Escobar-Pérez, T GonzálezHernández (CUBA-GERMANY / CUBA-ALEMANIA)210. VIRAL LOADS AND PHENOTYPIC MARKERS OF HIV PROGRESSION IN CUBAN PATIENTS. A6 Alvarez, A González, R Molina, C Luzardo, O Calderon. (CUBA). aileen@ipk.sld.cu211. INFECTIVITY STUDY OF DENGUE VIRUS STRAINS USING IMMUNOFLUORESCENCE7 TECHNIQUE. A Aguilar,N Amin, EM Pérez, G Bolaños, EC Rodríguez, A Talavera. (CUBA)12. SERUM LEVELS OF IL-12, IL-10, RANTES AND NITRIC OXIDE IN DENGUE VIRUS INFECTED2PATIENTS. AB Pérez, G García, T Denny, B Sierra, MV Cabrera, M Alvarez, J Bacallao, MG8Guzmán. (CUBA-USA / CUBA-EEUU). anab@ipk.sld.cu

13. TUMOR NECROSIS FACTOR ALPHA AND NITRIC OXIDE IN BLOOD CELLS SUPERNATANTS2STIMULATED WITH DENGUE VIRUS. AB Perez, G García, B Sierra, M Alvarez, MV Cabrera, L9Valdés, S Vázquez, MG Guzmán. (CUBA). anab@ipk.sld.cu314. ADCC AND DENGUE VIRUS INFECTION: CONTROL OR DAMAGE? G García, MC Arango, AB0 Pérez, L Fonte, B Sierra, R Rodríguez, E Aguirre, MG Guzmán. (CUBA). anab@ipk.sld.cu15. A DNA VACCINE OR RECOMBINANT PROTEINS BUT NOT HCV INOCULUMS INDUCED BOTHCELLULAR AND HUMORAL IMMUNE RESPONSES IN MACACA IRUS. A Vina-Rodriguez, S3Duenas-Carrera, R Martínez, JC Alvarez-Obregón, J Marante, B Gras, I Gonzalez-Perez, LAlvarez-LajonchEre, G Martinez Donato, EG. Rodríguez, G Guillen Nieto, K Cosme, J MoralesGrillo. (CUBA). Ariel.Vina@cigb.edu.cu16. MICE LYMPHOPROLIFERATIVE RESPONSES INDUCED BY A DEN4 TRUNCATED3RECOMBINANT E GLYCOPROTEIN. B Sierra, R Rodríguez, L Lazo, L Hermida, C López, G2García, AB Pérez, MG Guzmán. (CUBA). siebet@ipk.sld.cu17. THE RECOMBINANT DEN 2 ENVELOPE B DOMAIN ELICITS A STRONG SEROTYPE SPECIFIC3LYMPHOPROLIFERATIVE RESPONSE IN MICE. B Sierra, R Rodríguez, L Lazo, L Hermida, G3Guillen, MG Guzmán. (CUBA). siebet@ipk.sld.cu18. DIALYZABLE LEUKOCYTE EXTRACT (DLE) INHIBITS HIV-1 IN VITRO REPLICATION AS EARLY34AS 24 HOURS OF INCUBATION BEFORE VIRUS CHALLENGE IN MT-4 CELLS. Fernández-Ortega C, Ojeda M, Giselle A, Ramos Y, Navea L, Rodríguez L, Casillas D, Lovaina L, Noa E,Ruibal I, M Dubed. (CUBA) celia.fernandez@cigb.edu.cu19. MODIFIED VACCINIA VIRUS ANKARA (MVA) PRIMING AND FOWLPOX VIRUS BOOSTER3 ELICIT STRONGER CTL RESPONSE IN MICE AGAINST AN HIV-1 EPITOPE THAN DNA-5 POXVIRUS PRIME-BOOST APPROACH. D Vázquez-Blomquist, D Quintana, CA Duarte.(CUBA).dania.vazquez@cigb.edu.cu20. IMMUNIZATION WITH MAPs COUPLED TO CARRIERS: INFLUENCE OF THE EPITOPIC DENSITY3AND PRE-EXISTING IMMUNITY TO THE CARRIER. E Iglesias, JC Aguilar, S Martínez, HE Garay,6O Reyes. (CUBA). enrique.iglesias@cigb.edu.cu321. OZONE THERAPY IN AIDS. A CASE REPORT. N.I. Méndez, S. Menéndez, J. Rivero. (CUBA).7 ozono@infomed.sld.cu22. HLA ASSOCIATION IN CUBAN PATIENTS INFECTED WITH HUMAN IMMUNODEFICIENCY3VIRUS TYPE I. STUDY PRELIMINARY. I García, J Suárez, R Alegre, A Alvarez, J Pérez. (CUBA).8igprod@infomed.sld.cu23. IMPROVEMENT OF HCV-SPECIFIC IMMUNE RESPONSES USING A NEW VECTOR OF THE3pMAE PLASMID SERIE. J Marante, A Vina-Rodriguez, N Lorenzo, E Brown, EG Rodríguez, S9Duenas-Carrera. (CUBA). Ariel.Vina@cigb.edu.cu24. INDUCTION OF HUMORAL IMMUNE RESPONSE USING HUMAN INTERFERON ALPHA 2B AND40RECOMBINANT ANTI-HEPATITIS B VACCINE IN ASYMPTOMATIC CARRIER PATIENTS OFHEPATITIS B VIRUS. J A Santiesteban Torres, A González Griego, A Alerm González, J AcostaAcosta, V E. González, E García Castillo, A Montenegro, O Ponce de León (CUBA).25. ADJUVANT CAPACITY OF A LIPOPEPTIDE CONTAINING THE LALF31-52 PEPTIDE ON THE4 IMMUNE RESPONSE SPECIFIC TO THE HCV CAPSIDE INDUCED BY DNA IMMUNIZATION. JCAlvarez-Obregón, A Alvarez, L Alvarez-Lajoncherè, O Reyes, I Guerra, J Morales, S Dueñas-Carrera. (CUBA) jcaobregon@cigb.edu.cu26. CHARACTERIZATION AND IMMUNOLOGICAL EVALUATION OF TWO VARIANTS OF THE4 ENVELOPE DENGUE 2 PROTEIN. Laura Lazo, Lisset Hermida, Rayner Rodríguez, Aída Zulueta,2 Carlos López, Ricardo Silva, Glay Chinea, Jorge Martín, Guadalupe Guzmán, Gerardo Guillén.(CUBA). lisset.hermida@CIGB.edu.cu

27. RESPONSE OF NEUTRALIZING ANTIBODIES TO SOUTHEAST ASIAN AND AMERICAN4GENOTYPE OF DENGUE VIRUS TYPE 2. L Bernardo, A Yndart, S Vázquez, L Morier, MG3Guzmán.(CUBA). lidice@ipk.sld.cu28. IMMUNOLOGICAL EVALUATION OF TWO DIFFERENT CONSTRUCTS OF DENGUE-1-P64k44CHIMERIC PROTEINS. Lisset Hermida, Rayner Rodríguez, Laura Lazo, Lídice Bernardo, RicardoSilva, Aída Zulueta, Carlos López, Jorge Martín, Iris Valdés, Delfina del Rosario, Glay Chinea,Guadalupe Guzmán, Gerardo Guillén. (CUBA). lisset.hermida@cigb.edu.cu29. IMMUNIZATION WITH HCV SYNTHETIC PEPTIDES CONJUGATED TO CARRIER PROTEINS4ELICITED STRONG ANTIBODY RESPONSE WITHOUT ADJUVANT IN MICE. L Alvarez-5Lajonchere, G Martínez, J Morales, S Dueñas-Carrera. (CUBA). santiago.duenas@cigb.edu.cu30. EVALUATION OF MICE SERA IMMUNIZED WITH SYNTHETIC PEPTIDES OF DENGUE 2 VIRUS46USING ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY ASSAY. MC Montalvo, AB Pérez,G García, S Vázquez, MC Arango, G. Chinea, O Reyes, G Guillén, MG Guzmán. (CUBA).mcary@ipk.sld.cu31. EVALUATION OF A PANEL WITH ANTIHEPATITIS B POLICLONAL AND MONOCLONAL4 SERUMS FOR SURFACE ANTIGEN EXPRESION DETECTION BY ELISA OF THE HEPATITIS B7 VIRUS (HBSAG SUBTYPE AYW). M. Peña, Y. Pestana, S. Martinez. (CUBA).maxlenin@cigb.edu.cu32. PROCUREMENT OF REFERENCE MATERIALS AGAINST RECOMBINANT HBsAG SURFACE4ANTIGEN. MC Abrahantes, J Reyes, B Reyes, R Sosa, EM González, M Vega, D Arias, R8Valdés, E Martínez. (CUBA). mc.abrahantes@cigb.edu.cu33. EVALUATION OF AUTOREACTIVITY AFTER IMMUNIZATION OF BALB/C MICE WITH CUBAN4RECOMBINANT HEPATITIS B VACCINE. M. Romero, B. Sakic, O. Ponce de León. (CUBA-9CANADA) mromero@giron.sld.cu34. HEPATITIS C VIRAL CORE PROTEIN-EXPRESSING DNA VACCINE INDUCES A STRONG CTL5RESPONSE IN MICE. N Acosta-Rivero, S Dueñas-Carrera, L Alvarez-Lajonchere, J Morales.0(CUBA). nelson.acosta@cigb.edu.cu35. STUDY OF INFECTION ENHANCEMENT OF DENGUE STRAINS USING A MONOCLONAL5 ANTIBODY SPECIFIC TO A RECOMBINANT ENVELOPE PROTEIN FROM DENGUE VIRUS TYPE4. N Amin, M Pupo, R Rodriguez, M Alvarez, H Rodriguez, A Otero, G Guzmán. (CUBA).namin@finlay.edu.cu36. IMMUNOGENICITY STUDY OF BEAGLE DOGS FROM CELL CULTURE RABIES VACCINES.52Odalys Fidalgo Perera, Ernesto Almora Hernández, Arelys Zamora Fuentes, Georgina PardoGómez, Luis Izquierdo, Maylen Argamasilla Martínez, Niurka Rodríguez Pérez y Gustavo SierraGónzalez. (CUBA). ofidalgo@finlay.edu.cu37. SURFACE MARKERS OF HEPATITIS B VIRUS INFECTION AND RESPONSE TO VACCINATION5IN A COMMUNITY. Serrano O, Leyva A, Alerm A, González A. (CUBA).3orlando@labex.scu.sld.cu38. IgG BUT NOT IgM FROM DENGUE 2 IMMUNE HUMAN SERA REACTS WITH DENGUE 454TRUNCATED E GLYCOPROTEIN EXPRESSED IN PICHIA PASTORIS. Rayner Rodríguez, MayraMuné, Susana Vázquez, Gabriel Márquez, Lisset Hermida, Beatriz Sierra, Gerardo Guillén, MaríaG. Guzmán. (CUBA). rayner_rodriguez@yahoo.com39. IMMUNOLOGIC EVALUATION OF A DTP-HB VACCINE FORMULATION FOR NASAL5ADMINISTRATION. JC Aguilar, R Alemán, Y Lobaina, JC Álvarez, E Iglesias, D García, V Muzio,5E Hardy, E Pentón, D Urquiza, N Expósito, G Guillén. (CUBA). regis.aleman@cigb.edu.cu40. STUDY OF THE ANTIBODIES RESPONSE AGAINST DENGUE VIRAL PROTEIN IN PATIENTS5WITH PRIMARY AND SECONDARY INFECTIONS. Sheila Cabezas, Susana Vázquez, Maritza6Pupo, Naifi Calzada , Lissette Pérez and María G. Guzmán (CUBA). sheila@ipk.sld.cu

41. INFLUENZA VACCINE: HUMORAL IMMUNITY FOR THE A/JOHANNESBURG/82/96 IN AN5ELDERLY HOUSE.S Oropesa, A Fanjul, J Muñoz, B Acosta, A Piñón, B Espinosa, MA Oquendo,7O Soublet. (CUBA). s.oro@ipk.sld.cu42. KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS (KSHV) SEROPREVALENCE IN CUBAN5POPULATIONS. V Kourí, SM Eng, ME Rodríguez, S Resik, O Urraca, PS. Moore, Y Chang, L8González (CUBA). vkouri@ipk.sld.cu543. SEROLOGICAL SURVEILLANCE OF MEASLES, RUBELLA AND MUMPS. CUBA 1992-2002. G9 Torres, R Cancio, M ARibas, I Salazar. (CUBA). gisset@ipk.sld.cu44. RECOMBINANT HBsAg AGGREGATED "IN VITRO" BY OXIDATIVE STRESS : STUDIES OF ITS6ANTIGENIC PROPERTIES. Sewer M. , Ramirez W., Tleugabulova D., Fleitas Y., Aguilar J.,0Penton E. (CUBA). labrada@biocen.colombus.cuADJUVANTS1. ANALYSIS OF THE CARRIER PROPERTIES OF THE CRY PROTEINS OF Bacillus thuringiensisWHEN ADMINISTERED BY INTRAPERITONEAL AND INTRANASAL ROUTE. G Guerrero, FHernández Terán, L Moreno-Fierros. (MEXICO). gloriaguillermina@correo.unam.mx2. INTRANASAL ADMINISTRATION OF PEPTIDE T1SP10MN(A) CO-ADMINISTERED WITHCHOLERA TOXIN OR CRY1AC, INDUCE CHANGES IN POPULATIONS MUCOSAL2LYMPHOCYTES B AND T IN BALB/C MICES. R. Esquivel-Pérez, L. Verdín-Terán, L. Moreno-Fierros (MEXICO). mariespe86@hotmail.com.mx3. INDUCED IMMUNE RESPONSE FOR THE SIMULTANEOUS ADMINISTRATION OF A DNA3 VACCINE FOR Brucella abortus AND AN ADJUVANT PLASMID (pGM-CSF). A González, RRivers, E Andrews, A Oñate. (CHILE). andregon@udec.cl4. IgA ANTIBODIES AND SISTEMIC T-CELL TOLERANCE BY ORAL IMMUNIZATION WITH AN4 Entamoeba histolytica PROTEIN FUSED TO CHOLERA TOXIN SUBUNIT B. A Contreras-Rojas, AOlivos, P Ostoa, C Castellanos, JP Laclette, JC Carrero. (MEXICO). carrero@servidor.unam.mx5. EVIDENCES OF SPECIFIC IMMUNO STIMULATING EFFECT AND LOW TOXICITY OF AN5 NATURAL ADJUVANT CANDIDATE. Batista A, D Fernández, Urdaneta I, Betancourt J, Pérez O.(CUBA).6. EFFECT OF ACEMANNAN AND CALCIUM SALTS ON THE IMMUNE RESPONSE AGAINST6 DIFFERENT ANTIGENS. A Pérez, JC Aguilar, AM Herrera, D Urquiza, V Muzio, E Pentón, MJLeal, GE Guillén.(CUBA). anna.perez@cigb.edu.cu7. INFLUENCE OF DIFFERENT ADJUVANTS IN THE IMMUNOLOGICAL RESPONSE AGAINST7 DENGUE 2 VIRUS WITH A FUSION PROTEIN. C López, R Rodriguez, L Hermida, L Bernardo, JMartin, I Guerra, L Lazo, A Zulueta, G Guillen, G Guzman. (CUBA). carlos.lopez@cigb.edu.cu8. THE EGF ENCAPSULATION INTO LIPOSOMES MODIFIES ITS IMMUNE RESPONSE IN MICE. MC8 Luzardo, Y Martínez, L Calderón, Y De León, A De la Barrera, F Pazos, C Alvarez, ME Alonso,ME Lanio (CUBA). mcluzardo@fbio.uh.cu9. PREPARATION AND EVALUATION OF VI POLYSACCHARIDE-PROTEIN CONJUGATESCOMPOSED OF TETANUS TOXOID OR OMP FROM N. MENINGITIDIS SEROGROUP B AS A9CARRIER. M Cuello, O Cabrera, CR Soto, O Pérez, J del Campo, CM Taboada, M Fariñas, GSierra. (CUBA). mcuello@finlay.edu.cu10. DEVELOPMENT OF AN ADJUVATED VACCINE WITH RAPID DELIVERY AGAINST FOOT ANDMOUTH DISEASE VIRUS (FMDV). V. Quattrocchi, N. Fondevila, S. Pappalardo, A. Sadir, P.0Zamorano (ARGENTINA). pzamorano@cicv.inta.gov.ar11. CHARACTERIZATION OF P64k AS A CARRIER PROTEIN. S González, R Silva, A Alvarez, GGuillén, E Caballero, A Pérez, Z Cinza A Ruíz, F Dickinson, C Nazábal, G Sardiñas, T Serrano, JSosa, D Guzmán, O Gutiérrez. (CUBA). sonia.gonzalez@cigb.edu.cu12. CUBAN ANTI-HEPATITIS B IMMUNOGLOBULIN AS BIOLOGICAL ADJUVANT. V. E. González et2 al. (Cuba). victoria.gonzalez@infomed.sld.cu

13. P64K AS A CARRIER PROTEIN OF NEISSERIA MENINGITIDIS PORIN A PEPTIDES. G. Sardiñas,3 S. Gonzalez, HE Garay, C. Nazábal, O. Reyes, R. Silva. (Cuba). gretel.sardinas@cigb.edu.cuIMMUNODIAGNOSTICS1. OPTIMIZATION OF RECOMBINANT STREPTOLYSIN-O EXPRESSION AND ANALYSIS OF FINALPRODUCT FORMULATIONS SUITABLE FOR IMMUNODIAGNOSIS. B Velázquez, H Massaldi and6A Chabalgoity. (URUGUAY). bvela@higiene.edu.uy2. AUTOANTIBODIES AGAINST EXTRACTABLE NUCLEAR ANTIGENS. A URUGUAYANEXPERIENCE. MI Bethencourt, I Iacobovici. (URUGUAY-SPAIN/URUGUAY-ESPAÑA).7dosi@adinet.com.uy3. OBTENTION OF HIGH TITRE POLYCLONAL ANTISERA AGAINST PEPTIDIC HAPTENS:8 MICROCYSTIN LR AND MELITTIN. S Lev. (URUGUAY). sandlev@higiene.edu.uy4. HUMAN TRYPSINOGEN PURIFICATION FROM PANCREATIC TISSUE FOR CYSTIC FIBROSISIMMUNODIAGNOSIS. Antonio Melchor Rodríguez, Liliana Hernández Pérez, Orlando Zulueta9 Rodríguez, Carlos Martínez Ortiz, Raquel López Cisneros, Carmen Acosta Bas, Nimia FanegoSerrat, Amarilys Frómeta Suárez. (CUBA). iqpurifica@cie.sld.cu5. BETA-SUBUNIT HCG PURIFICATION FROM HUMAN CHORIONIC GONADOTROPIN FOR2 IMMUNODIAGNOSIS. Antonio Melchor, Orlando Zulueta, Juliette Cazanave, Liliana Hernández,0 Carlos Martínez, Ileana Baluja, Dunia Bequec, Celina Machado, Raquel López, Luisa Martínez,Milenen Hernández. (CUBA). iqpurifica@cie.sld.cu6. MONOCLONAL ANTIBODY AGAINST FREE BETA-SUBUNIT OF HUMAN CHORIONIC2 GONADOTROPIN. Ileana B. Baluja Conde, Adys I. Brito Moreno, Carmen Acosta Bas, OrlandoZulueta Rodríguez, Antonio Melchor Rodríguez, Isis Amores Sanchéz, Luisa Martínez, MilenenHernández. (CUBA). iqmonoclo1@cie.sld.cu27. TRANSGENIC ANTI COAGULATION FACTOR IX. M. Mahia, A. Dìaz, L. Perez, L.E. Ramos, A.2 Moya, A. Càdiz, M. Limonta. (CUBA). arquidia@infomed.sld.cu23248. IMMUNOLOGICAL CLASSIFICATION OF LYMPHO- AND MYELOPROLIFERATIVE SYNDROMESUSING THE ALKALINE PHOSPHATASE ANTI-ALKALINE PHOSPHATASE (APAAP) METHOD. BBSocarrás, V Marsán, M Sánchez, M Martínez, I Torres, LO del Valle, C Macías, RA Rivero.(CUBA). ihidir@hemato.sld.cu9. MONOCLONAL ANTIBODY AGAINST HUMAN TRYPSIN: PRODUCTION, CHARACTERIZATION,AND USE FOR DIAGNOSIS. Carmen Acosta Bas, Ileana B. Baluja Conde, Adys I. Brito Moreno,Maya Rosa Rodríguez López, Antonio Melchor, Liliana Hernández, Amarilys Frómeta, María E.Selles, Luisa Martínez. (CUBA). iqmonoclo@cie.sld.cu10. ENDOTHELIAL ADHESION MOLECULES ICAM-1, VCAM-1 AND E-SELECTIN IN PATIENTS2 WITH ACUTE CORONARY SYNDROME. Consuelo Macías , Rinaldo Villaescusa , Lázaro del5 Valle , Victor Boffil, Girelda Cordero, Alberto Hernández, Porfirio Hernández , José ManuelBallester. (CUBA). ihidir@hemato.sld.cu11. EVALUATION OF THE NEUTROPHILS RESPONSE USING THE REDUCTION OF THE NITRO BLUE2 OF TETRAZOLIUM(NBT) AND THE OPSONOPHAGOCYTIC INDEX TECHNIQUES. Edisley Zaila6 Lago, Yudania Reyes Cepero, Cándido León Márquez, Ernesto Caraballosa Yero. (CUBA).CubaZaila@escambray.ssp.sld.cu12. ENZYME-LINKED IMMUNOSORBENT ASSAY FOR 17a-HYDROXYPROGESTERONE (17OHP) IN2SERUM AND DRIED BLOOD SPOTS ON FILTER PAPER. E González, N Marrero, A Frómeta, M7Mónaga, D Herrera, E Castells, P Pérez, A Baloy, J Hernández. (CUBA). iqtsh@cie.sld.cu13. VALIDATION OF A NESTED PCR ASSAY UMELOSA HCV FOR DETECTION OF HEPATITIS C2VIRUS. I. Gonzalez-Perez, Y. J. González, A. Armas, A. Vina-Rodriguez, A. Medina, N. Trujillo,8M.T. Pérez, R.L. Solís. (CUBA). idania_gonzalez@yahoo.es14. EXPERIENCE OF THE IMMUNOASSAY CENTER IN THE PRODUCTION OF POLYCLONAL29ANTIBODIES FOR IMMUNODIAGNOSIS. L. Martínez; J.R. Vivar; V. Soto; A. Lorenzo; M.Montes de Oca; A. Melchor; O. Zulueta; P. Pérez; I. Valdivia; R. Cápiro; M.L. Hernández; R. DelSol. (CUBA). iqvivario@cie.sld.cu

15. LATEX TEST FOR SERUM MYOGLOBIN IN THE DIAGNOSIS OF ACUTE MYOCARDIAL3INFARCTION. MC Pico, IG Giraldino, M Alvarez, P Pedroso, H Carol. (CUBA).0mcpico@fbio.uh.cu16. CHIMERIC SYNTHETIC PEPTIDES CONTAINING TWO IMMUNODOMINANT EPITOPES FROM3 THE GAG P19 PROTEIN AND THE ENVELOPE GP46 GLYCOPROTEIN FOR THEIMMUNODIAGNOSIS OF HTLV-II VIRUS INFECTION. M Hernández, Y Márquez, L Pozo, C Silva,Ch Rodríguez, D Higginson. (CUBA). iqpeptidos@cie.sld.cu317. ANTIGENIC MIXTURE OF SYNTHETIC PEPTIDES FOR THE IMMUNODIAGNOSTIC OF HTLV-I/II.2 Y. Márquez, M. Hernández, R.A. Vázquez, L. Pozo, C Silva. (CUBA). iqvih@cie.sld.cu18. CELLULAR IMMUNOPHENOTYPING IN THE DIAGNOSIS OF CHRONIC LYMPHOID LEUKEMIAS.3M Sánchez, V Marsán, B Socarrás, RA Rivero, M Martínez, P Hernández, C Macías, LO del3Valle. (CUBA). m.sanchez@hemato.sld.cu19. DETECTION OF HLA-DR15 AND HLA-DQ6 BY PCR-SSP TECHNIQUE AND ITS USE IN THE3DIAGNOSIS OF NARCOLEPSY. Raul Ferreira, Flora Calzadilla, Adriana Artiles, Lizette Bonet,4Pedro Figueredo. (CUBA).20. THE USEFULNESS OF UMELOSA HCV CUALITATIVO KIT AS SUPPLEMENTAL TEST FOR3CONFIRMATION OF HCV INFECTION. I. Gonzalez-Perez, Y. J. González, A. Vina-Rodriguez, A.5Armas, R.L. Solís. (CUBA) idania_gonzalez@yahoo.es21. VALIDATION OF AN ELISA FOR THE QUANTITATION OF MONOCLONAL ANTIBODIES3AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEIN 24. N Ruiz , M6Izquierdo, E Silva, D Martín, MT Pérez. (CUBA). cicdc@infomed.sld.cu322. CUBAN ANTI-HEPATITIS B IMMUNOGLOBULIN WITH DIAGNOSTIC AIMS IN VIVO. E. García et7 al. (CUBA) elsagc@infomed.sld.cu23. IMMUNODIAGNOSTIC TEST FOR ANTIBODIES RESPONSE DETECTION AGAINST TICK38INFECTION IN BOVINE SERUM SAMPLES. E Torres, C Talavera, R Blanco, N Abad, H Machado,G Gómez. (CUBA) edel@escambray.ssp.sld.cuIMMUNOTECHNOLOGY1. DENDRITIC CELL IMMUNIZATION IMPROVES PRODUCTION OF MONOCLONAL ANTIBODIES4AGAINST THE REGULATOR OF MHC CLASS II EXPRESSION (CIITA). P Vargas, C Cortés, LVargas, M Rosemblatt, MR Bono. (CHILE). pabcovar@icaro.dic.uchile.cl4243444546472. OBTAINING VIRAL IMMUNOGENS BY MEANS OF THE FILAMENTOUS PHAGE DISPLAY.PRELIMINARY RESULTS. Ela María Pérez, Frank Camacho, Osmany Larralde, Félix Daphnis,Odalys Fidalgo, Raiza Martínez, Alicia Aguilar, Nevis Amin, Miriela Capo, Gustavo Sierra.(CUBA). Elaperez@finlay.edu.cu3. A SENSITIVE COMPETITION ELISA WITH IMMOBILIZED ANTIGEN FOR QUANTIFINGSTICHOLYSINS I AND II, TWO CYTOLYSINS FROM THE SEA ANEMONE Stichodactylahelianthus. A Otero, A Hidalgo, MC Pico. (CUBA). aoterog@infomed.sld.cu PDF4. PEROXIDASE-LABELED STICHOLYSINS METHOD FOR LOCALIZATION OF STICHOLYSINS INTHE SEA ANEMONE STICHODACTYLA HELIANTHUS. MC Pico, Y Noa, V Pérez, M Izquierdo, OGuerra, JF Infante, A Otero. (CUBA). mcpico@fbio.uh.cu5. NEUTRALIZATION OF HEMOLYTIC ACTIVITY OF STICHOLYSIN II, A CYTOLYSIN FROM THESEA ANEMONE Stichodactyla helianthus. MC Pico, A Basulto, I Casadelvalle, A.J. Otero.(CUBA). mcpico@fbio.uh.cu6. POLYCLONAL ANTIBODIES TO SHPI-1, A POLYVALENT PROTEASE INHIBITOR FROM THESEA ANEMONE STICHODACTYLA HELIANTHUS. I Casadelvalle, MC Pico, V Marañón, EFacenda, C Gilvá. (CUBA). isis@fbio.uh.cu7. VALIDATION OF COLORIMETRIC VIBRIOCIDAL ASSAY FOR DETERMINE SERUM ANTIBODIESTO Vibrio cholerae. Bárbara Cedré, Yutssandry Viel, Tamara Rodríguez, Gemma Año, IrmaGonzález, Ileana Delgado, Hilda García, Yadira Pino, Tania Valmaseda, Arturo Talavera, LuisGarcía. (CUBA). bcedre@finlay.edu.cu

8. VALIDATION OF ELISA FOR DETERMINE ANTIBODIES ANTI-LPS IN HUMAN SERUMINOCULATED BY ORAL ROUTE WITH 638 V. CHOLERAE STRAIN EL TOR OGAWA. Yadira4Pino Navarro, Tania Valmaseda Pérez, Yudisey Medina Sánchez, Bárbara Cedré Marrero,8Gemma Año López, Hilda M. García Sánchez, José Luis Pérez Quiñoy, Arturo Talavera Coronel,Irma González Novo, Ileana Delgado Arrieta y Luis García Imia (CUBA). ypino@finlay.edu.cu499. IMMUNOPURIFICATION OF THE HEPATITIS B SURFACE ANTIGEN USING A PLANT-DERIVEDHBsAg-SPECIFIC ANTIBODY. Rodolfo Valdés, Biunayki Reyes, Tatiana Alvarez, Janet García,Waldo Ortiz, José A. Montero, Raudel Sosa, Leonardo Gómez, Sigifredo Padilla, YurisleydisAldama , Alejandro Figueroa, Lamay Dorta, Damián Fernández, Deborah Geada and José Brito(CUBA). rodolfo.valdes@cigb.edu.cu10. INFLUENCE OF THE EXTRACTION BUFFER ON MONOCLONAL ANTIBODY QUANTITY AND5 INTEGRITY FROM TOBACCO PLANTS. Rodolfo Valdés, William Ferro,Sigifredo Padilla,0 Leonardo Gómez, Raudel Sosa, Roberto Pérez, Otto Mendoza,Merardo Pujol, Jose Enrique Brito.(CUBA). rodolfo.valdes@cigb.edu.cu11. OBTENTION OF CHICKEN ANTIBODIES THAT RECOGNIZE NUCLEOSIDE ANALOGS USED IN5 NON RADIOACTIVE DNA DETECTION. Dannelys Perez Bello, Judith Miranda, Mirta ZayasAcosta, Chryslaine Rodriguez Tanty, David Higginson Clarke, Ana María Riverón Rojas, EstebanGutiérrez Calzado, Rüdiger Schade. (CUBA-GERMANY / CUBA-ALEMANIA).12. MOUSE MONOCLONAL ANTIBODIES AGAINST ABO BLOOD GROUP ANTIGENS IN CUBA: ITS5EVALUATION IN THE 4TH INTERNATIONAL WORKSHOP. Rivero RA, Bencomo AA, Alfonso Y,2Suárez LE, Díaz M. (CUBA). rrivero@hemato.sld.cu.13. HUMAN HAEMOCLASSIFICATION BY USE OF SPECIFIC YOLK ANTIBODIES OBTAINED AFTER5IMMUNISATION OF CHICKENS AGAINST HUMAN BLOOD GROUP ANTIGENS. RM García, EJ3Gutiérrez, E Schade. (CUBA-GERMANY / CUBA-ALEMANIA). mireyita@cnt.uo.edu.cu14. COMPARISON OF THREE METHODS FOR NONRADIOACTIVE IN VIVO DNA LABELING IN5 Escherichia coli Dannelys Pérez Bello, Viana Manrique Suárez, Celso Pérez Bolaños, Judith4 Miranda López, Gabriel Pérez Pérez, Lilia López Canovas, David Higginson Clark, ChryslaineRodríguez Tanty, Ana Maria Riverón Rojas. (CUBA).15. RIBULOSE 1,5 DIPHOSPHATE; GENERATION OF MONOCLONAL ANTIBODIES FOR5 IMMUNOAFFINITY CHROMATOGRAPHY AND PROTEIN QUANTIFICATION. Déborah Geada,5 Rodolfo Valdés, Marcos González, Dioslaida Urquiza, Leonardo Gómez, Abdel Hidalgo, DulceMaría Ares. (CUBA). Rodolfo.valdes@cigb.edu.cu16. CLONING, EXPRESSION AND PURIFICATION OF HUMAN CD6 EXTRACELLULAR DOMAIN IN5E. COLI USED TO DETECTION HIORT1 MAB. E Santana, A Aguirre, L Ayra, G Márquez, J6Sánchez, Y Carpio, FO Castro. (CUBA). elaine.santana@cigb.edu.cu17. PRODUCTION OF MONOCLONAL ANTIBODIES BY THE ASCITES METHOD: A5 COMPREHENSIVE ANALYSIS OF THE SCALE TO REDUCE ANIMAL SUFERING. O. Mendoza, R.7 Valdés, R. Alemán, M. González, B. Reyes, S. Padilla,T. Alvarez, A. Tamayo, D. Fuentes, R.González, O. Hernández, J. Arronte. (CUBA). maria.rosario@cigb.edu.cu18. IDENTITY TEST OF THE OMV PROTEIN FROM CUBA VACCINE VA-MENGOC-BC® USING5MONOCLONAL ANTIBODIES. M. E. Pérez, Barbera R., Otero O., Domínguez F., Sotolongo F.8Sierra G, Campa C. (CUBA). meperez@finlay.edu.cu19. IMMUNOBLOT VERSUS ELISA FOR THE PRIMARY SCREENING IN THE DEVELOPMENT OF5 MOUSE MONOCLONAL ANTIBODIES AGAINST OUTER MEMBRANE PROTEINS OF Neisseria9 meningitidis B:4:P1.(7B).4. M. E. Pérez, Otero O., Barbera R., Gutiérrez M., Domínguez F.,Sotolongo F. Sierra G, Campa C. (CUBA). meperez@finlay.edu.cu20. GENE THERAPY USING NAKED PLASMID DNA ENCODING VEGF121 IN ANIMAL MODELS OFISCHEMIC DISEASES. AG Ojalvo, A Seralena, NS Vispo, R Silva, R Vázquez, Y Puchades, A Alí,6P Lopez-Saura, JF Montequín, LT Sorell, A Aldama, MA Alfonso, Rafael Simón, Armando Seuc,0N González, L Guevara, N Chaos, O Creach, R González, JF Batista, Y Peña, M Coca, A Perera,T García-Osuna, H Domínguez, JL Reyes, L Herrera. (CUBA). ariana.garcia@cigb.edu.cu

21. KINETIC OF EXPRESSION OF THE PLANTIBODY-HB01 SPECIFIC FOR THE SURFACE ANTIGENOF HEPATITIS B VIRUS IN Nicotiana tabacum (CUBA) Leonardo Gómez Bayolo, Merardo Pujol,6Rodolfo Valdés, William Ferro, Roberto Pérez, Sigifredo Padilla, José Brito, Carlos Borroto,Alberto Núñez, Milagro Font, René Gallo, Julio César Sánchez. (CUBA).Leonardo.gomez@cigb.edu.cu22. PROCCESSING OF FRESH TRANSGENIC TOBACCO PLANTS FOR PURIFICATION OF A HBsAg-6 SPECIFIC ANTIBODY. Rodolfo Valdés, Leonardo Gómez, Sigifredo Padilla, Merardo Pujol,2 Vladimir Leal, Orlando Herrera, Tatiana Alvarez, Otto Mendoza, Jorge Luis Vega, José Brito,Carlos Borroto. (CUBA). Rodolfo.Valdes@cigb.edu.cu23. DIRECT IDENTIFICATION OF TUMOR ANTIGENS BY AUTOLOGOUS ANTIBODY SCREENING. O63Gires, M Muenz, M Schaffrik, C Kieu, B Mack, W Hammerschmidt, R Zeidler. (GERMANY).ogires@hno.med.uni-muenchen.deTUMOR IMMUNOLOGY AND IMMUNOTHERAPY1. ADVANCES IN THE DETERMINATION OF TUMOR MARKERS IN COLORECTAL CARCINOMA. MV Croce, AG Colussi, G Ramacciotti, A Segal-Eiras (ARGENTINA). as-eiras@netverk.com.ar2. PATTERNS OF MUC1 TISSUE EXPRESSION DEFINED BY AN ANTI MUC1 CYTOPLASMIC TAIL2 MONOCLONAL ANTIBODY IN BREAST CANCER. MV Croce, M Isla-Larrain, C Rua, M Rabassa,A Segal-Eiras. (ARGENTINA). mrabassa@atlas.med.unlp.edu.ar3. EXPRESSION OF CARBOHYDRATE AND PEPTIDIC ANTIGENS IN BREAST CANCER. MV Croce,3M Isla-Larrain, C Rua, A Segal-Eiras. (ARGENTINA). as-eiras@netverk.com.ar4. INTRATUMORAL AND REGIONAL LYMPH NODES CYTOKINES GENE EXPRESSION IN BREASTCANCER PATIENTS. L Llanes-Fernández, MC Arango-Prado, JM Alcocer-González, V Madrid-4Marina, S Franco-Odio, R Camacho-Rodríguez, AM González-Sánchez, R Tamez-Guerra, CRodríguez-Padilla. (CUBA-MEXICO)5. WALKER 256 TUMOR MHC CLASS I EXPRESSION DURING THE SHIFT FROM "A" VARIANT5 INTO THE IMMUNOGENIC "AR" VARIANT. AS Schanoski, PB Juliano, CBL Campos, TCSCavalcanti, AN Viera-Matos, O Rettori, F Guimarães. (BRASIL/BRAZIL). aless007@yahoo.com6. THE ANTI-TUMORAL ACTIVITY OF VEGETAL SPECIES FOUND IN AMAZONIC REGION. FRF6 Nascimento, BTF Silva, JO Viana, GB Cruz, K Arruda, N Gadelha, RNM Guerra.(BRASIL/BRAZIL). nascimentofrf@yahoo.com.br7. POSSIBLE PARTICIPATION OF THE COMPLEMENT SYSTEM IN THE DEVELOPMENT OF7 AUTOIMMUNE MANIFESTATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA. R Villaescusa, etal. (Cuba). rvillaescusa@hemato.sld.cu8. TREATMENT OF LEUKEMIC CELLS (HL60) WITH DIMETHYLAMIDE-CROTONIN TRIGGERS8 APOPTOSIS DEPENDENT OF CASPASES -2 AND -9, BUT NOT CASPASE -6 ACTIVATION. MCAnazetti, PS Melo, N Durán, M Haun. (BRAZIL/BRASIL). mcanazetti@bol.com.br9. REGULATION OF Bcl-2 EXPRESSION IN LEUKEMIC CELLS (HL60) BY VIOLACEIN AS A9 MECHANISM OF APOPTOSIS INDUCTION. N Bromberg, PS Melo, C Bincoletto, GZ Justo, MHaun, N Durán (BRAZIL/BRASIL). natalia@iqm.unicamp.br.10. ANTITUMORAL ACTIVITY OF DEHYDROCROTONIN. PS Melo, GZ Justo, N Durán, M Haun.0 (BRAZIL/BRASIL). pmelo@unicamp.br11. POLYAMINES AS BIOMARKERS OF NEOPLASTIC GROWTH IN MICE WITH L5178YLYMPHOMA TREATED WITH Bursera fagaroides. R Reynoso, A Santerre, J I Delgado, CSandoval, A Puebla.(MEXICO). rreynoso@cucba.udg.mx12. RED BLOOD CELLS OSMOTIC FRAGILITY ALTERATIONS INDUCED BY TOTAL AND PLASMAFRACTIONS FROM RATS BEARING PROGRESSIVE AND REGRESSIVE VARIANTS OF WALKER2 256 TUMOR. TC Cavalcanti, CC Gregorini, F Guimarães, O Rettori, AN Vieira-Matos(BRAZIL/BRASIL). samico@caism.unicamp.br13. EFFECTOR, MEMORY AND NAIVE PHENOTYPES IN CYTOTOXIC T LYMPHOCYTES FROMLUNG ADENOCARCINOMA PATIENTS. H Prado-García, D Aguilar Cázares, H Flores-Vergara, H3Morales-Fuentes, F Ávila-Moreno, JS López-González. (MEXICO). hpradog@yahoo.com.

14. PULMONARY CARCINOMAS INDUCE ALTERATIONS IN DIFFERENTIATION, MATURATIONAND FUNCTION OF HUMAN DENDRITIC CELLS. F Ávila-Moreno, S J López-González, H Prado-4García, C Sánchez-Torres. (MEXICO). avilamore@hotmail.com15. MODULATION OF THE CELLULAR IMMUNE RESPONSE AND CYTOKINES PRODUCTION BY INVITRO PERILLYL ALCOHOL ON T CELLS FROM TUMOR-BEARING MICE. E Flores, S del Toro, A5del Toro, T García, MG Ramírez, A Daneri. (MEXICO). E-mail: inmeftdr@hotmail.com16. NKG2D AND 2B4 EXPRESSION ON NK CELLS FROM PATIENTS WITH CERVICALCARCINOMA. S del Toro, A del Toro, T García, J Peregrina, E Flores, MG Ramírez, A Daneri.6(MEXICO). susana@cucs.udg.mx17. EXPRESSION OF ZETA CHAIN IN T LYMPHOCYTES AND NK CELLS FROM PATIENTS WITHUTERINE CERVICAL CARCINOMA. T García, A del Toro, J Peregrina, E Sánchez, P Sánchez, S7del Toro, A Daneri. (MEXICO). tgarcia@cucs.udg.mx18. CD44-HYALURONIC ACID INTERACTION MODULATES METALLOPROTEINASES IN A T CELLMURINE LYMPHOMA AND IN INFLAMMATORY LEUKOCYTES. L Alaniz, P Cabrera, S8Greczanik, G Blanco, E Alvarez, SE Hajos. (ARGENTINA). laualaniz@yahoo.com19. IMMUNOTHERAPY OF ADVANCED BREAST CANCER WITH AN HETEROPHILIC GANGLIOSIDE2 (NEUGCGM3) CANCER VACCINE. A Carr, E Rodríguez, MC Arango, R Camacho, M Osorio, G0 Carrillo, Z Valdés, Y Bebelagua, M Gabri, R Pérez, LE Fernández. (CUBA-ARGENTINA).adriana@ict.cim.sld.cu20. EPIDERMAL GROWTH FACTOR RECEPTOR-BASED ACTIVE IMMUNOTHERAPY OF CANCER.Anabel de la Barrera. (CUBA). anabel@ict.cim.sld.cu21. EXPRESSION OF LYMPHOCYTE SURFACE ANTIGENS IN BREAST CANCER PATIENTS. A2González, E Noris, A Torrella, M C Arango, T Badía, M E Faxas. (CUBA).2alymar@infomed.sld.cu22. A MONOCLONAL ANTIBODY AGAINST NeuGc-CONTAINING GANGLIOSIDES CONTAINS A2REGULATORY IDIOTOPE INVOLVED IN THE INTERACTION WITH B AND T CELLS. A Perez, ES3Mier, N Santiago Vispo, AM Vazquez, R Perez. (CUBA). rolando@ict.cim.sld.cu23. A CHIMERIC ANTI-N-GLYCOLYL-GANGLIOSIDE ANTIBODY: IMMUNODOMINANCE OF ITS2VARIABLE REGION. A Lopez, C Mateo de Acosta, J Lombardero, K Sosa, R Perez, AM4Vazquez. (CUBA). maruchi@ict.cim.sld.cu24. IMMUNE RESPONSES IN BREAST CANCER PATIENTS IMMUNIZED WITH AN ANTI-IDIOTYPIC2ANTIBODY MIMICKING NeuGc-CONTAINING GANGLIOSIDES. A Díaz, M Alfonso, R Alonso, G5Saurez, M Troche, M Catalá, RM Díaz, R Pérez, AM Vázquez. (CUBA). maruchi@ict.cim.sld.cu25. A TGFa CANCER VACCINE. Ayllete Mulet, Greta Garrido, Anabel Alvarez, Tamara Menéndez,6 Rolando Pérez, Luis Enrique Fernández. (CUBA). luis@ict.cim.sld.cu26. EVALUATION OF THE HUMORAL IMMUNE RESPONSE TO NEUGCGM3/ VSSP VACCINE IN2 METASTATIC MELANOMA PATIENTS. A. Torrella, E. Noris, A. González, M.C. Arango, B.7 Rodríguez, M. Osorio, L. Anasagasti, E. Rodriguez, R. Mon, A. Carr, L.E. Fernández (CUBA).atorella@infomed.sld.cu.27. INDUCTION OF IMMUNE RECOGNITION TO AUTOLOGOUS EGFR. B Sánchez. A de la Barrera,8 E Suárez, R Pérez, A Ullrich, LE Fernández.(CUBA). belinda@ict.cim.sld.cu28. CD6+ CELLS IN BENIGN BREAST LESIONS AND CANCER DEVELOPMENT M E Faxas García, I9 Pérez B, M E Guerra Y. (CUBA). mefaxas@infomed.sld.cu329. RISK FACTORS AND IMMUNOLOGICAL PARAMETERS IN CERVICAL CANCER. G. León, ME0 Faxas, B. Rodríguez, O. Bosques Diego, R. Ruiz Lorente. (CUBA). mefaxas@infomed.sld.cu30. CHARACTERIZATION OF IMMUNOGENICITY AGAINST TWO GROWTH FACTORS (EGF AND3 TGF ALPHA) USING RECOMBINANT FUSION PROTEINS BETWEEN THESE MOLECULES ANDP64K PROTEIN FROM NEISSERIA MENINGITIDIS AS A NEW CANCER VACCINE APPROACH. GGarrido, A Mulet, A Álvarez, T Menéndez, L.E Fernández. (CUBA). greta@ict.cim.sld.cu31. LHRH BASED VACCINE DECREASE THE VOLUME OF PROSTATE IN ADULT MALE RATS. F32Fuentes, L Calzada, J Junco, R Basulto, E Bover, E Pimentel, Y López, H Hernández. (CUBA).franklin.fuentes@cigbcam.cigb.edu.cu

32. PERIPHERAL T CELL REGULATION AGAINST SELF-ANTIGENS IN AUTOIMMUNITY AND3CANCER. E. Montero, G. Nussbaum, J. Kaye, R. Perez, A. Lage, I. Cohen.(CUBA-ISRAEL).3enrique@ict.cim.sld.cu33. LEUKOCYTE AND RECOMBINANT INTERFERON IN THE TREATMENT OF MYCOSIS FUNGOIDE.3LONG-TERM SURVIVAL. A del Río, S Collazo, B Sagaró, B Gutiérrez, M Cortina, C Ochoa, C4Valenzuela, P López-Saura. (CUBA). amaury@cigbdec.cigb.edu.cu34. T CELL AND GANGLIOSIDES BASED VACCINES: ARE THEY INVOLVED? C. Mesa, Z. Mazorra,5 L.E.Fernández (CUBA) luis@ict.cim.sld.cu35. EVALUATION OF THE HUMORAL IMMUNE RESPONSE TO NEUGCGM3/ VSSP VACCINE IN3 ADVANCED BREAST CANCER PATIENTS. E. Noris, A. Torrella, A. González, MC. Arango, B.6 Rodríguez, M. Osorio, L. Anasagasti, E. Rodriguez, R. Mon, A. Carr, L.E. Fernández. (CUBA).anoris@infomed.sld.cu36. IMMUNOGLOBULIN DISTURBANCES IN PATIENTS WITH HODGKIN´S DISEASE. A Arce, R37Villaescusa, JC Merlín, AM Guerreiro, LM Morera, C Ustariz, P Hernández. (Cuba).ihidir@hemato.sld.cuANTIGEN PRESENTATION/TRANSPLANTATION1. THE DECREASE ON T CELL COUNTS AFTER A SINGLE DOSE OF IMMUNOSUPPRESSIVE4 DRUGS IN RENAL TRANSPLANT PATIENTS CAN BE ASCRIBED TO A LOW DOSE OF6 PREDNISONE. D Sauma, R Mora, A Fierro, J Morales, C Herzog, M Rosemblatt, MR Bono.(CHILE). dmsauma@mi-mail.cl42. REPRESENTATION OF CLASS I AND II ANTIGENS IN RECEIVERS OF KIDNEY GRAFTS. M C7 Clares, M. Domínguez. (CUBA). ucilora@hsl.scu.sld.cu3. HLA EXTENDED HAPLOTYPES IN A SAMPLE OF THE CUBAN CONTEMPORARY POPULATION.R Alegre, I Garcia, J Suárez, J Beltrán, J Martínez-Laso, E Gómez-Casado, A Arnaiz-Villena.(CUBA-SPAIN / CUBA-ESPAÑA). cmcaiba@capiro.vcl.sld.cu4. GENETIC AND PHENOTYPICAL FREQUENCY STUDY OF HLA ANTIGENS INOPHTHALMOLOGICAL DISEASES: VOGNT - KOYANAGI - HARADA AND PRIMARY OPENANGLE GLAUCOMA. LM Morera et al. (CUBA) ihidir@hemato.sld.cu4849OTHER TOPICS I51. ALTERATIONS OF THE COMPLEMENT SYSTEM IN PATIENTS WITH DIABETIC NEPHROPATHY.5 JC Merlín et al. (CUBA). jc.merlin@hemato.sld.cu2. INTRODUCTION OF IMMUNOLOGY TEACHING TO THE STUDY PLAN FOR THE PHARMACY5CAREER AND ITS IMPORTANCE FOR THE PROFESSIONAL PERFORMANCE OF GRADUATES.6Beatriz Tamargo Santos et al. (CUBA) betty@ifal2.uh.cu53. ZINC SUPPLEMENTS AND IMMUNE SYSTEM CELLS FUNCTIONS IN DIABETICS. Mahia VM et7 al. (CUBA). mmahia@infomed.sld.cu4. ACTION OF THE INJECTABLE EXTRACTS OF ALOE BARBADENSIS ON THE APPEARANCE OF5 INFECTIOUS COMPLICATIONS AND THE LEVELS DE INMUNOGLOBULINS. M Rodríguez8 Acosta, E Castellano Port, T Vazquéz González, A Sin Mayor, M Larionova, N Johnston Dreke,RA Moya. (CUBA) ismmds@infomed.sld.cu5. EFFECT OF THE RFC2A ABOUT THE CELLULAR VIABILITY DE HUMAN NEUTROPHILS. A SinMayor, M Larionova, Map ecechea Coffigny, N Johnston Dreke. (CUBA)ismmds@infomed.sld.cu6. EFFECT OF THE INJECTABLE EXTRACT OF ALOE BARBADENSIS ON THE LYMPHOBLASTICTRANSFORMATION OF THE BURNT PATIENT. T Vazquéz González, M Rodríguez Acosta, ECastellano Port, A Sin, M Larionova, N Johnston Dreke, RA Moya. (CUBA)ismmds@infomed.sld.cu596067. ANTIVIRAL EFFECT OF TWO TINTURES OBTAINED OF HYPERICUM CULTIVATED IN CUBA. ECastellanos Puerto, JL Pérez de Alejo, Ml Machin Lugones. (CUBA). ismmds@infomed.sld.cu

IMMUNOLOGY OF PARASITE DISEASES1. ROLE OF IL-4 IN EXPERIMENTAL INFECTION BY THE HELMINTH Echinococcus granulosus. GFerragut, S Dematteis, A Baz. (URUGUAY). gferragu@bilbo.edu.uy2. THE ATHYMIC LEW-Whn10rnu "NUDE RAT" AS A MODEL TO STUDY T-CELL INDEPENDENTMECHANISMS OF RESISTANCE AGAINST T. gondii. JC Sepulveda-Arias, MC Kempf, D2Wedekind, HJ Hedrich, MF Cesbron-Delauw, U Gross, T Herrmann. (COLOMBIA-GERMANY-FRANCE/COLOMBIA-ALEMANIA-FRANCIA). jcsepulv@rocketmail.com3. T CELL UNRESPONSIVENESS IN RATS CONGENITALLY INFECTED WITH THE PARASITE3 Toxoplasma gondii. JC Sepulveda-Arias, T Herrmann. (COLOMBIA-GERMANY/COLOMBIA-ALEMANIA). jcsepulv@rocketmail.com4. STUDIES ABOUT IMMUNE RESPONSE IN RATS INFECTED WITH Toxoplasma gondii VIA MILK.4 JC Sepulveda-Arias, J Nussbaumer, T Herrmann. (COLOMBIA-GERMANY/COLOMBIA-ALEMANIA). jcsepulv@rocketmail.com5. DIFFERENTIAL PHAGOCYTIC CAPACITY OF Nramp1 GENE CONGENIC MACROPHAGE LINES5 TO THE INFECTION WITH CONIDIAS OF Paracoccidioides brasiliensis. M del P Jiménez, ARestrepo, LE Cano, LF García. (COLOMBIA). lfgarcia@udea.edu.co6. CELL EXPRESSION OF COSTIMULATORY MOLECULES NO DIFFERS IN PATIENTS WITHLOCALIZED CUTANEOUS LEISHMANIASIS AND ENDEMICALLY EXPOSED ASYMPTOMATICS.6CM Trujillo, M Zuluaga, PJ Patiño, ID Vélez, SM Robledo. (COLOMBIA).sara_robledo@yahoo.com7. EXPRESSION OF PEPTIDE-HLA COMPLEXES IN INFECTED MACROPHAGES WITH Leishmania7brasiliensis. S Télles, F Puerta, S Santaella. (VENEZUELA). stelles@telcel.net.ve8. MODULATION OF THE COMPLEMENT SYSTEM BY Trypanosoma cruzi CALRETICULIN. V8 Ferreira, S Tzima, A Gringas, MC Molina,C Valck, A Rojas, W Schwaeble, A Ferreira. (CHILE-UK/CHILE-REINO UNIDO). vferreira@canela.med.uchile.cl9. IMMUNOPATHOGENESIS OF GLOMERULONEPHRITIS IN VISCERAL LEISHMANIASIS (VL)9 INVOLVES CD4+ T CELLS, IMMUNOGLOBULIN AND MODULATION OF APOPTOSIS. H Goto,FAL Costa, R Mathias, MG Prianti, A Sesso, J L Guerra. (BRAZIL/BRASIL). hgoto@usp.br10. AMEBIC CYSTEINE PROTEINASE 2 (EhCP2) PLAYS EITHER A MINOR OR NO ROLE IN TISSUEDAMAGE IN ACUTE EXPERIMENTAL AMEBIC LIVER ABSCESS IN HAMSTERS. A Olivos-García,0 A González, R López, MC García de León, E Tello, M Nequiz, I Montfort, R Pérez-Tamayo.(MEXICO). olivosa@yahoo.com11. EVALUATION OF THE ROLE OF CELL-MEDIATED IMMUNITY IN DERMATOPHYTOSIS . ARKhosravi, M Franco, M Mahmoudi. (IRAN-BRAZIL/IRAN-BRASIL). khosravi@chamran.ut.ic.ir12. APOPTOSIS AND CYTOKINE PROFILE IN THE EVOLUTION OF EXPERIMENTAL VISCERALLEISHMANIASIS. JAL Lindoso, FA Pettito, FA Freitas, H Goto. (BRAZIL/BRASIL).2jlindoso@usp.br13. MALARIA IN THE SUB SAHARAN AFRICA. KO Agyapong, GK Nyarko, AM Koomson.3 (GHANA). gyec28@yahoo.co.uk14. SPECIFIC TRANSFER FACTOR PROTECTS MICE AGAINST LETHAL TOXOPLASMOSIS. A.Rodríguez, I. Vila, A. Moya, J. Hernández, L. Solarana, A. Cadiz, M. Limonta, J. O. Rodríguez,4A. Fachado (CUBA). alex18@giron.sld.cu15. CONSTRUCTION AND EVALUATION OF IMMUNOGENICITY AND INDUCED PROTECTION INBALB/C MICE IMMUNIZED WITH A GENOMIC LIBRARY OF EXPRESSION OF TRYPANOSOMA5 CRUZI. A Ruiz Espinosa, E Alberti Amador, AM Montalvo Alvarez, R García Miniet, MB.Martínez Benitez, ME Sarmiento García San Miguel, A Acosta Domínguez (CUBA).16. SIGNIFICANT PROTECTIVE EFFECTS OF NAKED DNA BASED IMMUNIZATION FROM LETHALTOXOPLASMOSIS IN MICE. A. Rodríguez, A. Fachado, I. Vila, J. L. Gonzalez, A. Acosta, M. E.6Sarmiento. (CUBA). alex18@giron.sld.cu17. CELLULAR INMUNITY ALTERATIONS IN PATIENTS WITH RECURRENT GIARDYASIS. B Ferrer,7 G Reiter, M. C Clares. (CUBA). soimi@hsl.scu.sld.cu

18. IMMUNOMODULADOR EFFECT OF THE VIMANG AND MANGIFERINA IN THE THE IMMUNEHUMORAL RESPONSE TO THE SPORES OF A MICROSPORIDIAN PARASITE . Dagmar García8 Rivera, René Delgado Hernández, Florencio Martínez Ubeira, José M. Leiro Vidal. (CUBA-SPAIN/ CUBA-ESPAÑA). dagmarg75@yahoo.es19. EVALUATION OF AUTORREACTIVITY IN BALB/C MICE IMMUNIZED WITH NUCLEIC ACIDSFROM Trypanosoma cruzi. Aniran Ruiz Espinosa, Esteban A. Amador, Martha Rodriguez Peña,9 Arturo Münster, O. Ponce de León, María E. Sarmiento García San Miguel, Armando AcostaDomínguez, Gustavo Sierra (CUBA). aruiz@ipk.sld.cu20. INTESTINAL AMEBIASIS. IMMUNOLOGICAL AND BIOMOLECULAR DEMONSTRATION OF THE2 OVERESTIMATION OF A HEALTH PROBLEM. Luis Fonte Galindo, María de los A. Fernández0 Ferrer, Lizet Sanchez Valdés, Humberto Marín Iglesias, Ivón Montano Goodridge. (CUBA).fonte@ipk.sld.cu21. IgA ANTIBODIES AND SISTEMIC T-CELL TOLERANCE BY ORAL IMMUNIZATION WITH AN2Entamoeba histolytica PROTEIN FUSED TO CHOLERA TOXIN SUBUNIT B. A Contreras-Rojas, AOlivos, P Ostoa, C Castellanos, JP Laclette, JC Carrero. (MEXICO) carrero@servidor.unam.mx22. HUMORAL AND CELULAR ESPECIFIC RESPONSE IN BALB/C MICE IMMUNIZED WHITH A2GENOMIC EXPRESSION LIBRARY OF TRYPANOSOMA CRUZI. Mignelys Padilla Rivas et al.2(Cuba).23. INDUCTION OF PROTECTION AND SYSTEMIC AND MUCOSAL ANTIBODY RESPONSES IN23MICE IMMUNIZED INTRANASALLY WITH Naegleria fowleri EXTRACT TOGETHER WITHCry1Ac AS AN ADJUVANT. S Rojas, M Rodríguez, R Campos, R López, L Moreno. (MEXICO).saulrohe@yahoo.com.mxIMMUNODEFICIENCIES1. A B CELL IMMUNODEFICIENCY IN AN EIGHT-MONTH CHILD WITH BCG VACCINATION. G2López, A Garibay, A Esparza, G Galindo, L Flores, R Hernández, B Alvarez, M Pérez, S Estrada, I6Estrada, L Santos. (MEXICO). lohegaby@hotmail.com2728292. HEMIN: IN VITRO EFFECT ON HUMAN LYMPHOCYTES FROM HEALTHY BLOOD DONORS. LOdel Valle, V Marsán, M Sánchez, I Torres, BB Socarrás, M Martínez, C Macías, RA Rivero, PHernández, JM Ballester. (CUBA). l.valle@hemato.sld.cu3. JALEA REAL: AN EFFECTIVE ALTERNATIVE FOR THE TREATMENT OF PATIENTS WITHCELLULAR INMUNODEFICIENCY. O. de la Guardia, J. Espinosa, T Planos, M. Savigne, L.Nogueira, Z Lemus. (CUBA).4. USE OF INTRAVENOUS GAMMAGLOBULIN IN PRIMARY IMMUNODEFICIENCY. A. Noda, B.Rodríguez, A.Vidal. (CUBA). E mail anoda@unecavar.cuSIGNAL TRANSDUCTION / CELL INTERACTIONS1. MOLECULAR APPROACHES TO THE STUDY OF THE PROTEIN OF 67 KDa (p67phox) OF THE3NADPH OXIDASE SYSTEM OF PHAGOCYTIC CELLS. AA Arias, MC Dinauer, J Ding, MT4Rugeles, PJ Patiño. (COLOMBIA-USA/COLOMBIA-EEUU). aarias@catios.udea.edu.co2. T-KININOGEN INHIBITS CON A-STIMULATED MAPK ACTIVITY IN LYMPHOCYTES ANDMACROPHAGES. C Acuña-Castillo, M Aravena, E Leiva-Salcedo, V Pérez, C Gómez, SNishimura, R Walter, F Sierra. (CHILE-USA/CHILE-EEUU). acunabioqco@yahoo.com3. PREFERENTIAL DEVELOPMENT OF CD4+CD25+ SUPPRESSOR T CELLS WITH DISTINCT TCRCHARACTERISTICS IN MICE EXPRESSING A SINGLE PEPTIDE-MHC CLASS II COMPLEX. MAGavin, JD Fontenot, E Negrou, Y Zhu, I Wilson, R Strong, AY Rudensky. (USA/EEUU).mgavin@u.washington.edu, fontenot@u.washington.edu3536374. MECANISMS OF DOWN-REGULATION OF MHC CLASS II (MHC-II) BY IMMUNE COMPLEXES(IC) ON HUMAN MONOCYTES. P Barrionuevo, M Beigier-Bompadre, GC Fernández, S Gómez,MS Palermo, MA Isturiz. (ARGENTINA). pbarrion@hotmail.com

5. GENE EXPRESSION IN CELLS TRANSFECTED WITH DIFFERENT ISOFORMS OF CIITA. C3Cortés, D Munroe, L Gangi, M Rosemblatt, MR Bono. (CHILE-USA/CHILE-EEUU).8ccortes@icaro.dic.uchile.cl36. No inhibition of the citotoxicity activity on human natural killer cells by anti alpha 4 chain9 monoclonal antibodies. C. Macías , del Valle L.O., Ballester J.M. (CUBA). ihidir@hemato.sld.cu407. EFFECT OF IFN-g ON THE EXPRESSION OF SMAD-7 IN HEPATIC STELLATE CELLS "HSC". IYañez-Sanchez, P Alatorre-Carranza, M Bueno-Topete, V Delgado-Rizo. (MEXICO).vidal@cencar.udg.mxIMMUNOLOGY OF ALLERGIC DISEASES1. IgE AND MAST CELLS CO-SEGREGATION IN ORAL TOLERANCE GENETICALLY SELECTED4STRAINS OF MICE. AC Silva, RC Ribeiro, MS Levy, MFS Silva, O Sant'Anna. (BRAZIL/BRASIL).6dasilva@uerj.br42. ALLERGENIC POLLENS AND POLLINOSIS IN SANTANDER CITY, SPAIN. V de Benito, C Sainz,7 J Soto. (SPAIN/ESPAÑA). sainzc@unican.es43. IgE REACTIVITY TO RECOMBINANT ALLERGENS FROM Blomia tropicalis IN CUBAN ALLERGIC8 PATIENTS. L Puerta, A Labrada, L Caraballo. (COLOMBIA-CUBA). lpuerta@enred.com4. A COMPARATIVE EVALUATION OF SERUM EOSINOPHIL CATIONIC PROTEIN (S-ECP) ANDTOTAL BLOOD IgE AS DIAGNOSTIC PARAMETERS IN PEDIATRIC ASTHMA. TG Naidu, JQueiroz, ALC Bessa. (BRAZIL/BRASIL) talapala_gn@yahoo.co.uk5. ETIOPATHOGENIC ROLE OF FUME OF FISH'S FLOUR FACTORIES IN THE DEVELOPMENT OFALERGIC MANIFESTATIONS BY CHILDREN AT THE PROVINCE OF CHANCAY, LIMA, PERU. JLAguilar Olano, R Capcha Mendoza, P Rojas, A Ramos, P Hurtado T., E Sanchez, I Goyzueta.(PERU). jaguilar@upch.edu.pe49506. BIOLOGICAL ACTIVITY OF ISOLATED MAJOR ALLERGENS OF Dermatophagoides siboney. B5Navarro, E Facenda, A Más, A Labrada, RL Castro, Y Oliva, M Febles. (CUBA)labrada@biocen.colombus.cu57. STABILITY OF IGE BINDING ACTIVITY OF DOMESTIC MITE ALLERGENS. A Labrada, E2 Facenda, N Lorenzo, A Más, R Quintero. (CUBA). labrada@biocen.colombus.cu8. CONTAMINATION WITH MITE ALLERGENS IN THE DOMESTIC ENVIRONMENT OF ALLERGIC5CHILDREN. L Infante, A Labrada, E Facenda, RL Castro, B. Fernández , B Luis (CUBA).3labrada@biocen.colombus.cu9. ISOLATION AND CHARACTERIZATION OF A LOW MOLECULAR WEIGHT ALLERGEN5FRACTION OF Blomia tropicalis. A Labrada, M Labrada, K Uyema, B Navarro, M Febles, L4Puerta (CUBA-COLOMBIA). labrada@biocen.colombus.cu10. CHARACTERIZATION OF rBlo t 13, RECOMBINANT ALLERGEN FROM Blomia tropicalis USING5MONOCLONAL ANTIBODIES. M Labrada, K Uyema, M Sewer, A Labrada, M González, L5Puerta, L Caraballo. (CUBA-COLOMBIA). labrada@biocen.colombus.cu11. LIPOSOME ENCAPSULATION OF THE MAJOR ALLERGENS OF Dermatophagoides siboney FOR5SPECIFIC IMMUNOTHERAPY. L. Calderón, E. Facenda, Y. Martínez, A. Otero, M.C. Pico, A.6Labrada, M.E. Lanio. (CUBA). leslycd@fbio.uh.cu12. NUCLEIC ACIDS ENCODING A HOUSE DUST MITE ALLERGEN FROM Dermatophagoides5siboney. O. Jorge, R.J. Romero, B. Fernández, B. Luis, D. Torralba, B.González (2) and A.7Labrada. (CUBA). labrada@biocen.colombus.cu13. DIAGNOSTIC EFFICACY OF THE SKIN PRICK-TEST, USING ALLERGEN EXTRACTS OF5COMMON DOMESTIC MITES, IN CUBAN CHILDREN. RL Castro, R Andina, A Labrada, D Fabré,8Y Oliva, M González. (CUBA). labrada@biocen.colombus.cu14. DIAGNOSTIC EFFICACY OF THE SKIN PRICK-TEST, USING ALLERGEN EXTRACTS OF59COMMON DOMESTIC MITES IN A CUBAN ADULT POPULATION. RL Castro, A Labrada, AAbdo, R Espino, M Ronquillo, M González, RE Aranda. (CUBA). labrada@biocen.colombus.cu

15. DEVELOPMENT OF ELISA BASED ON SPECIFIC POLYCLONAL ANTIBODIES, FOR6QUANTIFYING THE GROUP 1 MAJOR ALLERGEN OF HOUSE DUST MITES. K Uyema, M0Montesino, A Labrada, M Febles. (CUBA). labrada@biocen.colombus.cu16. NEW APPROACH FOR in vitro DIAGNOSIS OF THE SPECIFIC IgE RESPONSE TO CYNODON6DACTYLON POLLEN. L. Díaz, A. Montenegro, A Gonzales, A Dacourt, M Romero, O Ponce deLeón, O Glez, R Rodríguez. (CUBA). libertad@giron.sld.cu617. BRONCHIAL ASTHMA. -TREATMENT WITH INTACGLOBÍN (INTRAVENOUS2 GAMMAGLOBULIN). A. Noda, A.Vidal, B. Rodríguez. (CUBA). E mail anoda@unecavar.cuVETERINARY IMMUNOLOGY1. IMMUNE RESPONSE OF THE EQUINE INFECTIOUS ANEMIA DISEASE VIRAL GP 45 PROTEINTO A SYNTHETIC PEPTIDE IN MICE. A Soutullo, MI García, A Racca, A Baillat G Capello, JCPerin, G Tonarelli, I Malan Borel.(ARGENTINA). soutullo@fbcb.unl.edu.ar2. DEVELOPMENT AND EVALUATION OF AN ENZYME-LINKED INMUNOSORBENT ASSAY FORQUANTIFICATION OF THE HUMORAL RESPONSE OF CATTLE VACCINATED AGAINST2Campylobacter fetus. MV Repiso, MA Baraibar, MA Olivera, S Silveyra, J Battistoni(URUGUAY). mbarai@higiene.edu.uy3. APOPTOSIS IN LUNGS OF PIGS INTRATRACHEALLY INOCULATED WITH Mycoplasma3 hyopneumoniae. ST Cruz ST, G García-Tovar, J Luna, S Martínez R, L Flores, R Mena.(MEXICO). tonatiuh86@hotmail.com4. LYSOSOMAL DEGRANULATION IN POLYMORPHONUCLEAR NEUTROPHILS: A NOVEL4 MECHANISM OF SURVIVAL OF PATHOGENIC b-HEMOLYTIC Staphylococcus aureus IN THEBOVINE MAMMARY GLAND. TG Naidu. (BRAZIL/BRASIL). talapala_gn@yahoo.co.uk5. IMMUNOCHEMICAL CHARACTERIZATION OF PORINS FROM SALMONELLA SEROVARS OF5 IMPORTANCE IN POULTRY. A Estrada Garcia, B Ortiz Lopez, VF Ortiz Navarrete. (MEXICO).alioshaeg@yahoocom.6. COMPARISON OF DIFFERENT ROUTES IN THE Brucella abortus DNA VACCINATION. E6Andrews, A Cabrera, A González, R Rivers, H Folch, A Oñate.(CHILE). aonate@udec.cl7. CLONING AND CHARACTERIZATION OF THE CHICKEN YOLK SAC IGY RECEPTOR. AP West7Jr, PJ Bjorkman. (USA/EEUU). apwest@its.caltech.edu8. INTRASPLEEN IMMUNIZATION OF BALB/C MICE WITH A DNA VECTOR FOR BRUCELLA8 ABORTUS. C A Muñoz; E Andrews, S Cespedes, G Donoso, A Oñate. (CHILE).carmunoz@udec.cl9. DETECTION AND COUNTING OF MAST CELLS IN PIG'S LUNG INFECTED EXPERIMENTALLY9 WITH MYCOPLASMA HYOPNEUMONIAE. ST Cruz , SS Martínez Robles, LJ Tórtora, FGGarrido, LM Vega, RL Flores. (MEXICO). tonatiuh86@hotmail.com10. LACK OF SPECIFIC HUMORAL IMMUNE RESPONSE, IN A CALF LATENTLY INFECTED WITHBOVINE HERPES VIRUS 1.1. AN EPIDEMIOLOGICAL RISK. P Alonzo, U Benavides, F Isnardi, R0 Puentes, H Carol, J Bonnevaux, N Fondevila, SA Romera, AM Sadir, J Maisonnave.(URUGUAY-ARGENTINA). jacmaiso@hotmail.com11. EVALUATION OF A NEW MARKER BHV-1 VACCINE TO INDUCE PROTECTION AGAINSTVIRUS INFECTION IN CATTLE WHEN ADMINISTERED SUBCUTANEOUSLY. SA Romera, MPuntel, MP Del Médico Zajac, P Zamorano, P Maliandi, N Mattion, AM Sadir (ARGENTINA).aromera@cicv.inta.gov.ar12. EVALUATION OF PROTECTION CONFERRED BY INACTIVATED BHV-1 OR BHV-5 VACCINESAGAINST BHV-5 INFECTION. MP Del Médico Zajac, SA Romera, M Puntel, P Zamorano, M2Alegre, P Maliandi, N Mattion, AM Sadir A.M. (ARGENTINA). pauladmz@sinectis.com.ar13. DNA VECTORS FOR Brucella abortus. R Rivers, A González, E Andrews, A Oñate. (CHILE).3 aonate@udec.cl14. IgG IN SERUM, TISSUE AND PLACENTAL EXTRACTS AT DIFFERENT TIMES DURING SWINEPREGNANCY. M Koncurat, O Riesco, A Garro, G Yaful, D Williamson, D Lacolla. (ARGENTINA).4mkoncurat@ayv.unrc.edu.ar

15. INDUCTION OF CD8+ T CELLS IN THE INFECTION CAUSED BY Brucella abortus. R LópezSantiago, J Ríos Garcés, A López Merino, G Schurig, MC Moreno Lafont. (MEXICO).5rlopez@encb.ipn.mx16. HUMORAL IMMUNE RESPONSE IN ALPACAS INFECTED EXPERIMENTALLY WITH FASCIOLA6 HEPATICA. O S Timoteo, V Neyra, G Leguia, JR Espinoza (PERU). 05915@upch.edu.pe17. NRAMP1 EXPRESSION CORRELATES WITH HIGH LEVELS OF iNOS AND MHC INGRANULOMAS OF M. bovis infected cattle. A.L. Pereira, C. Estrada-Chavez, C. Arriaga, M.7Hernádez, R. Mancilla. (MEXICO). analauraps@hotmail.com18. COMPARATIVE STUDY OF THE IMMUNE RESPONSE OF FIVE DIFFERENT SPECIES OF TILAPIA8 (Oreochromis). J. Casas, A. Santerre, R. León, G. Zaitseva. (MEXICO). jcasas@cucba.udg.mx19. STUDY THE EFECT OF LEAD IN VIVO IN THE IMMUNE RESPONSE OF RED TILAPIA9 (Oreochromis mossambicus). R Solis, G Zaitseva (MEXICO). ricasol@cucba.udg.mx20. HUMORAL IMMUNE RESPONSE TO BOOPHILUS MICROPLUS BM95 ANTIGEN IN MICE,2 FOLLOWING A DNA PRIME-PROTEIN BOOST IMMUNIZATION STRATEGY. Gianna Izquierdo,0 Omar Farnós, Diana M. González, Marisdania Joglar, Elsa Rodríguez, Ricardo Lleonart. (CUBA).Ricardo.lleonart@cigb.edu.cu21. IMMUNODETECTION OF COLONIZING ANTIGENS IN ENTEROTOXIGENIC ESCHERICHIA COLI2 CELLS ISOLATED FROM PIGLETS WITH DIARRHOEA IN CUBA. M D Castro, A Campal, NArteaga, A Miranda, J Junco, L León, S Casas, T Alvarez, F Fuentes. (CUBA).Marilo.castro@cigbcam.cigb.edu.cu22. EVALUATION OF A MONOCLONAL ANTIBODIES PANEL DIRECTED AGAINST FIMBRIAL2 ANTIGENS K88, K99, F41 AND 987P OF ENTEROTOXIGENIC ESCHERICHIA COLI. J Junco, A2 Campal, A Miranda, M Castro, N Arteaga, S Casas , L León, T Alvarez, D Sanchez, GFernández, G Fontirroche. (CUBA). Jesus.junco@cigbcam.cigb.edu.cu23. EVALUATION OF A COMPETITIVE ELISA IN THE IMMUNE RESPONSE OF THE RABBIT2HAEMORRHAGIC DISEASE VIRUS. O. Valdés, M. García, L. Izquierdo (CUBA).3morier@ipk.sld.cu24. REPONSE TO MITOGENS BY PERIPHERAL PORCINE LYMPHOCYTES IN THE PERI-2IMPLANTATIONAL PERIOD. C. Greco, F. Cuello and Vivas, A. (ARGENTINA).4cgreco@exa.unrc.edu.ar25. ADDITIONAL VALUE OF THE CONSERVATION OF THE CUBAN CREOLE DONKEY FOR25PRODUCTION OF HIPERIMMUNE SERA. Eduardo Sánchez Blanco, Hiram Fong Rodríguez,Román Sánchez Pompa, Gustavo Sierra González, Francisco Velásquez Rodríguez. (Cuba).dimitrov@granma.inf.cuCYTOKINES / INFLAMMATION1. A SYNTHETIC PEPTIDE HOMOLOGOUS TO THE FUNCTIONAL DOMAIN OF HUMAN2INTERLEUKIN 10 DOWNREGULATES THE EXPRESSION OF THE MHC CLASS I ALPHA CHAIN6AND TAP 1/2 IN HUMAN MELANOMA CELLS. M Kurte et al. (CHILE). mkurte@hotmail.com2. INTER-INDIVIDUAL VARIATIONS ON CONSTITUTIVE IL-10 mRNA AND PROTEIN LEVELS AND2ITS ASSOCIATION WITH GENETIC POLYMORPHISMS. A Suárez, P Castro, R Alonso, L Mozo,7C Gutiérrez. (SPAIN/ESPAÑA). anasua@correo.uniovi.es23. A RAPID PROCEDURE FOR DISRUPTION OF WHITE BLOOD CELLS IN PRODUCTION OF8 TRANSFER FACTOR. C Noyola, D Castillo. (MEXICO). cecilnoyola@hotmail.com4. SELECTED MICE FOR ORAL TOLERANCE RESISTANCE: POSITIVE CORRELATION TO2INFLAMMATORY RESPONSE. MFS Silva, CS Bianchi, AC Silva, TC Barja-Fidalgo, F Cunha, A9Nóbrega. (BRAZIL/BRASIL). dasilva@uerj.br5. MURINE PERITONEAL MACROPHAGE ACTIVATION BY Orbignya phalerata (BABASSU)3TREATMENT. FRF Nascimento, AP Azevedo, ESB Barroqueiro, RNM Guerra, M Russo.0(BRAZIL/BRASIL). nascimentofrf@yahoo.com.br36. ADHESION OF B CELL LINES TO TONSIL ENDOTHELIAL CELLS INDUCES MHC CLASS IIMOLECULES. L Vargas, L Reyes, M Rosemblatt, MR Bono. (CHILE) lsalas@uchile.cl

7. ASSOCIATED INTERLEUKIN-1 COMPOSITE GENOTYPE IN MEXICAN ALZHEIMER PATIENTS. M3Méndez, R Valdés, G Silva, J Villalba (MEXICO) leonardommr@todito.com,2leonardomiguel@prodigy.net.mx8. MAJOR HISTOCOMPATIBILITY COMPLEX CLASS II (MHC) POLYMORPHISMS IN PATIENTSWITH IDIOPATHIC PULMONARY FIBROSIS (IPF). R Falfán, A Camarena, G Pérez, V Muñoz, ACamacho, A Juárez, M Selman. (MEXICO). dcb_rfalfanv@hotmail.com9. IN VITRO AND IN VIVO IFNg REGULATION OF CHEMOKINE RECEPTORS IN PERIPHERALBLOOD LEUKOCYTES FROM PATIENTS WITH ATOPIC AND INFLAMMATORY DISEASES.REGULATORY ROLE OF IFN g IN ATOPIC AND INFLAMMATORY DISEASES. Iraldo Bello Rivero,Cimara Bermudez, Madelyn Rodríguez, Elizabeth Blanco, Yanelda García, Yudith Rodríguez,Carmen Valenzuela, Pedro López Saura. (CUBA). Iraldo.Bello@cigb.edu.cu333410. STRESS-INDUCED DELETERIOUS INFLAMMATORY EVENTS OF THE HAIR FOLLICLE CAN BE3 COUNTERACTED BY A TOPICALLY ACTIVE HAIR GROWTH STIMULATOR. AC Zenclussen,4 EMJ Peters, E Hagen, BF. Klapp, R Paus, PC Arck. (ALEMANIA-ARGENTINA/GERMANY-ARGENTINA). ana.zenclussen@charite.de11. LOW BUT NOT HIGH DOSES OF ANTI-TNF-A OR ANTI-IFN-G ARE PROTECTIVE IN A MURINE3MODEL OF SEPTIC SHOCK. R Márquez, G Ramírez, A Díaz, J Paniagua, R Bojalil. (MEXICO).6marquezric@hotmail.com12. ARSENIC DELAYS IL-2 SYNTHESIS AND DOWNREGULATES CD4 AND CD8 EXPRESSION IN3HUMAN T LYMPHOCYTES STIMULATED WITH PHA. G Galicia, R Leyva, E Tenorio, P7Ostrosky, R Saavedra. (MEXICO). edatenorio@hotmail.com13. T CD3+ LYMPHOCYTES AT THE DIFFERENT INTESTINAL COMPARTMENTS SHOW DISTINCT3INTRACELLULAR CYTOKINES PROFILES. A Reséndiz-Albor , M Méndez- Rodríguez, R Valdés, R8López-Revilla, L Moreno-Fierros. (MEXICO). alreal@correo.unam.mx14. DECREASE OF T LYMPHOCYTES PROLIFERATIVE RESPONSE AND CYTOKINES LEVELS BY3TRYPSIN. PE Sánchez-Hernández, A del Toro-Arreola, S del Toro-Arreola, A Daneri-Navarro.9(MEXICO). pesh1978@hotmail.com15. IL-10 INDUCES DISRUPTION OF LIPID RAFTS MOBILIZATION IN MURINE BONE MARROW-4DERIVED DENDRITIC CELLS. G Acosta-Pérez, ME Castro-Mussot, R Tascón, B Stockinger, MJ0Colston, FJ Sánchez-García. (MEXICO-UK/MEXICO-REINO UNIDO). fsanchez@bios.encb.ipn.mx16. EFFECT OF AN EXTRACT OF Uncaria tomentosa (UÑA DE GATO) ON THE PRODUCTION OFTHE TUMORAL NECROSIS FACTOR - ALPHA IN A MODEL IN VIVO AND ITS ACTION LIKE AN4ANTI-INFLAMMATORY AGENT IN VITRO. P A Rojas, O S Timoteo, R Capcha, A Marcelo, APlaza, R Bauer, I Merfort, J L Aguilar. (PERU-GERMANY/PERU-ALEMANIA).projas@eudoramail.com17. TOLL-LIKE RECEPTORS (TLRs) EXPRESSION IN HUMAN MIXED BLOOD MONONUCLEAR4 CELLS FROM PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) AND2 CYTOKINE SERUM PROFILE. N Ramírez-Cruz C Maldonado, M Cuevas-Urióstegui, I Secundino,J Castañón, C López, I Estrada, A Isibasi. (MEXICO) E-mail: noraramirezc@hotmail.com18. THE -308 TUMOR NECROSIS FACTOR PROMOTER POLYMORPHISM IN SEVERE SEPSIS. J.4Guerrero, G. Echevarría, F. Nickel, C. Rodas, A. Cruzat, J. Contreras, A. Dotte, J. Castro, J.C.3Aguillón. (CHILE). Email: jguerrer@ns.hospital.uchile.cl19. PRO-INFLAMMATORY INTERLEUKINS IN TWO HEALTHY POPULATIONS EXPOSED TO4DIFERENT LEVELS OF AIR POLLUTING AGENTS. A.C. González-Villegas, M.L. Pita-López, V.4Davydova, E. Moreno-Ramírez, G. Zaitseva. (MEXICO). anac.glez.villegas@itesm.mx20. DIALYZABLE LEUKOCYTE EXTRACT (DLE) MODULATES CCR5 AND MIP-1a IN MT-4 cells.4Ojeda M, Chávez L, Rodríguez L, Casillas D, Ramos , C Fernández-Ortega. (CUBA).5Celia.fernandez@cigb.edu.cu21. ELEVATED cAMP LEVELS COULD MEDIATE THE DIFFERENTIAL EFFECTS OF DIALYZABLE46LEUKOCYTE EXTRACT (TRANSFER FACTOR) ON INFLAMMATORY EVENTS IN LEUKOCYTES.M Ojeda Ojeda, C van 't Veer, C Fernandez-Ortega, M Araña, WA Buurman. (CUBA-THENETHERLANDS / CUBA-HOLANDA). Miriam.ojeda@cigb.edu.cu

22. EFFECT OF THE PROTEIN AND VITAMIN A DEFICIENCY IN THE DIET ON THE GENE4EXPRESSION OF THE INTERLEUKIN 1 (IL-1). de las Cagigas A., Ferreira R., Sanchez V.,7Mengheri E. (CUBA-ITALY / CUBA-ITALIA).23. IFNa 2b INDUCES APOPTOSIS AND PROTEASOME-MEDIATED DEGRADATION OF P27KIP1 IN4A HUMAN LUNG CANCER CELL LINE. A Moro, SE Perea, C Pantoja, A Santos, MJ Araña, M8Serrano. (CUBA). alejandro.moro@cigb.edu.cu PDF424. IL-15 REGULATES HPV E7 IN A CERVICAL CANCER CELL LINE. A. Santos, R. Cruz, Y. Morera,9 A. Moro, S. Perea. (CUBA). alicia.santos@cigb.edu.cu25. EXPRESSION OF IL-13rh/Ckm FUSED PROTEIN IN THE MURINE MYELOMA CELL LINE J558L5AC Campal, A Santos, A de la Hera (CUBA-SPAIN / CUBA-ESPAÑA).0acampal@cigbcam.cigb.edu.cu26. IL-1alpha AMPLIFIES THE PROLIFERATION OF TF-1 CELLS CULTIVATED IN THE PRESENCE OF5 IL-13rh/Ckm. NEW STRATEGY TO DETERMINE THE BIOLOGICAL ACTIVITY OF THE IL-1aINTERLEUKINE. AC Campal, A de la Hera. (CUBA-SPAIN / CUBA-ESPAÑA).acampal@cigbcam.cigb.edu.cu27. ESTABLISHMENT OF THE LIMITS OF ACCEPTANCE OF THE FINAL PURIFIED PRODUCT OF5 THE PRODUCTION PROCESS OF THE RECOMBINANT HUMAN INTERLEUKIN-2. Isabel2 Apezteguía, Adriana M. Perera, Danny Perez, Haydée Gerónimo, Galina Moya, NiurmysMartínez, Maribel Vega, Raudel Sosa, Fidel H. Breña (CUBA). isabel.apezteguia@cigb.edu.cu28. THE INFLUENCE OF SOME DEGRADATION PATHWAYS ON THE BIOLOGICAL ACTIVITY OF5IFN ALPHA 2B, INTERLEUKIN 2 AND EPIDERMAL GROWTH FACTOR. Ll Ruiz, M Zurita, N3Reyes, L Duany, H Gerónimo, K Aroche, E Hardy. (CUBA). llamil.ruiz@cigb.edu.cu29. DEVELOPMENT OF LIQUID AND FREEZE-DRIED FORMULATIONS OF INTERFERON ALPHA 2B.5Ll Ruiz, N Reyes, J Sotolongo, L Duany, J Ferrero, K Aroche, E Hardy. (CUBA).4llamil.ruiz@cigb.edu.cu30. NEW FORMULATIONS OF INTERLEUKIN-2 RETAINING THE BIOLOGICAL ACTIVITY OF THE5CYTOKINE. N Reyes, Ll Ruiz, K Aroche, J Sotolongo, K Soto, H Gerónimo, E Hardy. (CUBA).5Eugenio.Hardy@cigb.edu.cu31. EVALUATION OF THE CYTOKINES PATTERN IN AN ANIMAL MODEL OF RHEUMATOID5ARTHRITIS. MC Domínguez, D García del Barco, C Taylor, D Urquiza, D Rodríguez, J Suárez, A6Vázquez, N Merino, K Cosme, G Padrón. (CUBA). mcarmen.dominguez@cigb.edu.cu32. EFFECTS OF LBP-DERIVED PEPTIDES ON TNF-ALPHA PRODUCTION IN AN EXPERIMENTAL5MODEL OF ENDOTOXIC SHOCK. AM Rodríguez, I Rodríguez-Alonso, I Hernández, MJ Araña.7(CUBA). amarcos@infomed.sld.cu33. EFFECT OF ANTI-LPS PEPTIDES IN THE EXPRESSION OF GAMMA INTERFERON IN A MURINE5MODEL OF INFECTION WITH Salmonella typhimurium. I Hernández Ramirez, I Rodríguez-8Alonso, M Araña Rosaínz. (CUBA). ilihern@giron.sld.cu PDF34. ADMINISTRATION OF LBP-DERIVED PEPTIDES IN TWO DIFFERENT ANIMAL MODELS OF5SEPSIS. I Rodríguez-Alonso, AM Rodríguez, I Hernandez, MJ ArañA. (CUBA).9ingrid.rodriguez@cigb.edu.cu635. KAWASAKI DISEASE (KD). TREATMENT WITH INTRAVENOUS GAMMAGLOBULIN. A. Noda,0 A.Vidal, B. Rodríguez. (CUBA). anoda@unecavar.cu36. CIRCULATING LEVELS OF PRO-INFLAMMATORY CYTOKINES AND OTHER MARKERS OF6INFLAMMATION IN SEVERELY BURNED CHILDREN. F. Iglesias, N. Salazar, M. Colás, A.Magdariaga, M.J. Araña (CUBA). Manuel.Arana@cigb.edu.cu37. THE PROTEIN BPI (bactericidal/permeability-increasing) IMPROVES THE SURVIVAL IN6 NEONATAL EXPERIMENTAL SEPSIS BY Escherichia coli. Javier Mancilla-Ramírez, Pilar García-2 Roca, J. Jesús Gaitán-Meza, Norma del Carmen Galindo-Sevilla, Francisco Javier Larios-Medina.(MEXICO). javiermancilla@hotmail.com38. INCREASE OF THE SOLUBLE RECEPTORS OF IL-1 AND TNFa IN SEPTIC NEONATES TREATED63WITH GM-CSF AND INTRAVENOUS IMMUNOGLOBULIN (IVIG). Javier Mancilla-Ramírez, IrmaElia Arce-García, Jacqueline Lara-Sánchez, Federico Javier Ortiz-Ibarra, Norma del CarmenGalindo-Sevilla. (MÉXICO). javiermancilla@hotmail.com

39. CANDIDATE VACCINE STRAINS OF VIBRIO CHOLERAE INDUCE A DIFFERENTIAL AND6 SPECIFIC ARRAY OF THREE PROINFLAMMATORY CYTOKINES IN INTESTINAL EPITHELIAL4 CELL LINE. BL. Rodríguez, A. Rojas, J. Campos, T. Ledon, E. Valle, K. Marrero, R. Fando.(Cuba). boris@biocnic.cneuro.edu.cu PDF640. THE EXPRESSION OF CO-STIMULATORY MOLECULES AND CYTOKINES SECRETION DEPEND5 IN PART OF PROLACTIN. Chávez-Rueda K et al. (MEXICO). kchavez@avantel.netOTHER TOPICS II1. DIFFERENCES BETWEEN THE LARGE AND SMALL INTESTINE ON THE PHENOTYPE OFLAMINA PROPRIA LYMPHOCYTES. A Reséndiz-Albor, M Méndez- Rodríguez, R López-Revilla, LMoreno-Fierros. (MEXICO). alreal@correo.unam.mx2. EVALUATION OF IMMUNOTOXICITY OF CHRONIC INTOXICATION WITH SODIUM ARSENITEIN Balb/c MICE. C Escudero-Lourdes, CE Medina de la Garza, R Quezada-Calvillo. (MEXICO).clauescu@yahoo.com3. IgG CONTAINING CELLS IN INTRAEPITHELIAL AND LAMINA PROPIA INTESTINALCOMPARTMENTS ARE INCREASED BY INTRAPERITONEAL IMMUNIZATION WITH Cry1Ac. LVerdín Terán, RM Esquivel Pérez, L Moreno Fierros. (MEXICO). chinicuil_2000@yahoo.com4. THE IMMUNOSUPPRESSIVE EFFECT OF LUPEOL AND ITS DERIVATIVES ON ANTIBODY ANDCELLULAR MEDIATED IMMUNE RESPONSES. RNM Guerra, AM Mendes, LMS Silveira, RSGOlea. (BRAZIL). rguerra@elo.com.br5. EXPERIMENTAL MODEL OF HYPOTHALAMIC-PITUITARY-ADRENAL AXIS ACTIVATION-INDUCED IMMUNOSUPPRESSION IN BALB/C MICE. JM Viveros, AM Puebla, L Sandoval, MMVillaseñor. (MEXICO). jviveros99@hotmail.com6. EFFECT OF Ginkgo biloba EXTRACT, EGB 761 ON THE CELLULAR IMMUNE RESPONSE IN ANHYPOTHALAMIC-PITUITARY-ADRENAL AXIS ACTIVATION MODEL. MM Villaseñor, AMPuebla. (MEXICO). mmvilla@cucs.udg.mx7. IMMUNOMODULATOR AND NEUROPROTECTOR ROLES OF FKBP51 AND FKBP52IMMUNOPHILINS IN UNIPOLAR AND BIPOLAR DEPRESSION. L. Pavón-Romero, G. Sandoval-López, I. Estrada-García, M. Pérez-Tapia, L. Gómez-Caudillo, J. Moreno, I. Arango, D. Gutiérrez,U. Ávila-Ordóñez, A. Hernández, C. Labastida, L. Álvarez, G. Heinze. (MEXICO).lkuriaki@imp.edu.mx8. ROLE OF DENDRITIC CELLS IN ORAL TOLERANCE INDUCED DURING MICE LIFETIME. PUSimioni, DL Gabriel, LS Scuro, LGR Fernandes, WMSC Tamashiro. (BRAZIL).wirlatam@unicamp.br9. PHAGOCYTOSIS INMUNOMODULATION IN Balb-c 53 MICE FED WITH "MACA" Lepidiummeyenii AND "UÑA DE GATO" Uncaria tomentosa. A. Guerra, R. Gazis, J. Ramos (PERU).agscinmune@yahoo.es10. THE USE OF INTRAVENOUS IMMUNOGLOBULINS IN THERAPY OF INTRACTABLE EPILEPSY. E.Rojas, A. Cádiz, N. Sardiñas. (CUBA). acadiz@finlay.edu.cu12. OVERVIEW OF THE BIOCHEMISTRY AND SAFETY OF AN INTACT INTRAVENOUS1IMMUNOGLOBULIN, pH 4.5. A. Cádiz, M.E. Castellano, A. Moya, J. Hernández, A. Rodríguez, E. Sosa, L.Joo. (CUBA). acadiz@finlay.edu.cu14. IMMUNOMODULATING ACTIVITIES OF PLEUROTUS OSTREATUS DERIVED PREPARATIONS.1H.J. Morris, J. Marcos, G. Llauradó, N. García, R.C. Bermúdez, Y. Lebeque. (CUBA).hmorris@cebi.uo.edu.cu15. HEPATIC HEMATOPOYESIS IN THE MICE WITH MYELOSUPPRESSION WITH1 CYCLOPHOSPHAMIDE AND TREATED WITH ALOE BARBADENSIS MILLER. José de La PazNaranjo, Maria del Carmén Sotolongo Baro, Maria E. Perdomo Paiba, Odalys Matos Reyes.(CUBA). ismmds@infomed.sld.cu

16. A METHODOLOGIC VARIANT FOR THE REQUEST OF COMBINED VACCINE REGISTRY.1 Adriana Maria Perera, Néstor Expósito, Isabel Apezteguía, Caridad Torres, Xenia Muñoz, NubiaGonzález, Maxlenin Peña, Rafael Sánchez, Eduardo Martínez (CUBA).adriana.perera@cigb.edu.cu17. ESTABLISHMENT OF THE SYSTEM OF DOCUMENTATION OF A PRODUCT IN RESEARCH AND1 DEVELOPMENT STAGE. Nubia N. González, Isabel Apezteguía, Maxlenin Peña, Dinorah Torres,Yaí Cruz, Llamil Ruiz, Matilde López, Natacha Pérez , Rolando Páez , Eduardo Martínez (CUBA).nubia.gonzalez@cigb.edu.cu18. LIQUID PASTEURIZATION OF AN IMMUNOGLOBULIN PREPARATION WITHOUT STABILIZER.1A. Cádiz, M. E. Castellano, A. Moya, A. Rodríguez, J. Hernández, L. Joo. A. Puig. (CUBA).acadiz@finlay.edu.cu19. PHAGOCYTIC FUNCTION OF POLYMORPHONUCLEAR NEUTROPHIL (PMN) LEUKOCYTES: A1COMPARISON BETWEEN FRESH AND 24 HOURS-OLD CELLS. I Torres, LO del Valle, V Marsán, M Sánchez, B Socarrás, M Ponce, RA Rivero, C Macías. (CUBA). ihidir@hemato.sld.cu20. STUDENT-SCIENTIFIC WORK IN IMMUNOLOGY TEACHING TO STUDENTS IN BIOCHEMISTRY.MC Pico, ME Alonso, J Díaz-Brito. (CUBA). mcpico@fbio.uh.cu21. IMMUNOLOGY TEACHING TO STUDENTS IN BIOLOGY, BIOCHEMISTRY AND MICROBIOLOGY.2ME Alonso, MC Pico, A Otero, I Casadelvalle, L Calvo, G León, E Salas, J Díaz-Brito. (CUBA).marige@rect.uh.cu22. CELLULAR IMMUNITY IN PATIENTS WITH CHRONIC GINGIVITIS EARLY AND LATEPERIODONTITIS. V. Hernandez, M. Chinea. (CUBA). inmuno@capiro.vcl.sld.cu23. IN VITRO EFFECT OF ATEROMIXOL ON LYMPHOBLASTIC TRANSFORMATION AND ON2ACTIVE ROSETTES FORMING CELLS. C. Insua, L. del Valle, C. Macias. (CUBA).borrajer@infomed.sld.cu24. IN VITRO EFFECT OF ACCUTE EXPOSURE TO LEAD ON HUMAN PERIPHERAL BLOOD2 MONONUCLEAR CELLS. Miguel Angel Hernández -Urzúa, Galina Zaitseva -Petrovna, CeliaGuerrero Velazquez, Iris Estrada García, Mary Fafutis -Morris (MEXICO).angelhdez@terra.com.mx25. ANTICOMPLEMENTARY ACTIVITY IN INTRAVENOUS IMMUNOGLOBULIN PREPARATIONS. AAArce et al. (Cuba) a.arce@hemato.sld.cuIMMUNOLOGY AND REPRODUCTION1. MOLECULAR MECHANISMS INVOLVED IN THE IN VITRO MODULATION OF HUMORALIMMUNE RESPONSES BY ESTROGEN AND PROGESTERONE. I Alvarez, L Berod, A Canellada,RA Margni. (ARGENTINA). ramargni@ffyb.uba.ar.2. DENDRITIC CELLS (DCs) MODULATE THE ASYMMETRIC ANTIBODIES PRODUCTION IN THECBA/J x DBA/2J MURINE ABORTION MODEL. S Blois, S Olmos, AC Zenclussen, T Gentile, PCArck, RA Margni (ARGENTINA-GERMANY/ARGENTINA-ALEMANIA). sblois@ffyb.uba.ar3. FUNCTIONAL AND PHENOTYPIC RESPONSE OF THE HUMAN NK CELLS IN NORMAL ANDPATHOLOGICAL PREGNANCY. J Puente, K Hidalgo, D Miranda, C Sepúlveda. (CHILE).jpuente@ciq.uchile.clAUTOIMMUNITY AND AUTOIMMUNE DISEASES1. INTRAVENOUS IMMUNOGLOBULIN THERAPY IN STEVENS-JOHNSON SYNDROME. I. Navia, B.Conde, F. Castellano, A. Cádiz. (CUBA). acadiz@finlay.edu.cu2. -308 TUMOR NECROSIS FACTOR-ALPHA PROMOTER POLYMORPHISM IN PATIENTS WITHRHEUMATOID ARTHRITIS AND OSTEOARTHRITIS IN THE WEST OF MEXICO: PRELIMINARYRESULTS. E Oregón-Romero, JF Muñoz-Valle, S Ruiz-Quezada, BT Martín-Márquez, G Martínez-Bonilla, G Bernard-Medina, A Daneri-Navarro, M Vázquez-del Mercado. (MEXICO).biologiamolecular@hotmail.com

3. THE -308 POLYMORPHISM IN THE PROMOTER REGION OF TUMOR NECROSIS FACTOR GENEAND EX VIVO LIPOPOLYSACCHARIDE-INDUCED TNF EXPRESSION IN PATIENTS WITHAGGRESSIVE PERIODONTITIS AND/OR TYPE 1 DIABETES MELLITUS. F González, C Pérez , AAguirre, V Pavez, V Araya, I Schiattino, J Cuenca, A Cruzat, JC Aguillón. (CHILE). fgonzalez@ns.hospital.uchile.cl4. RECOGNITION OF THE 117-125 PEPTIDE OF THE HSP60 FROM Klebsiella pneumoniae BY CD8T CELLS FROM ANKYLOSING SPONDYLITIS PATIENTS. F Zambrano-Zaragoza, D González-Juárez, R Burgos-Vargas, L Domínguez-López; M Cancino-Díaz, L Jiménez-Zamudio, E García-Latorre. (MEXICO) jzambran@att.net.mx; jzambran@nayar.uan.mx5. PAI-1 PROMOTER POLYMORPHISM IN PATIENTS WITH RHEUMATOID ARTHRITIS:PRELIMINARY RESULTS. S Ruiz-Quezada, JF Muñoz-Valle, BT Martín-Márquez, G Martínez-Bonilla, E Oregón-Romero, G Bernard-Medina, A Daneri-Navarro, M Cardenas-Meza, R Ascencio-Mendoza, M Vázquez-del Mercado. (MEXICO) biologiamolecular@hotmail.com6. THE ROLE OF CD4+CD25+ T LYMPHOCYTES ON INDUCTION OF ORAL TOLERANCE TOMYELIN BASIC PROTEIN. LMB Santos, A S Farias, JC Moraes, DEM Hallal, EC Oliveira, FGPereira, I Lorant- Metze. (BRAZIL/BRASIL). leonilda @unicamp.br7. UNBIASED IDENTIFICATION OF ANTIGEN SPECIFICITIES OF CEREBROSPINAL FLUID-INFILTRATING T CELLS IN MULTIPLE SCLEROSIS. M Sospedra, Y Zhao, G Blevins, C Mora, RSimon, C Pinilla, R Martin. (SPAIN-USA/ESPAÑA-EEUU). SospedrM@ninds.nih.gov8. CROSS REACTIVITY BETWEEN NON-CONSTITUTIVE EPIDERMAL ANTIGENS ANDSTREPTOCOCCAL ANTIGENS IN PSORIASIS. R Pérez-Lorenzo, D Sánchez-Sosa, M Chan-Avilés, G Abasolo-Flores, E López-Pacheco, G Bricaire-Bricaire. (MEXICO).rolperez@mail.uacam.mx9. THE ROLE OF HEAT SHOCK PROTEINS IN THE PATHOMECHANISM OF DIABETES MELLITUS.V Kecskemeti, A Szebeni, Z Prohaszka, K Tekes, Gy Fust. (HUNGARY/HUNGRIA).kecsval@pharma.sote.hu10. SELECTIVE DEPLETION OF Vb2+CD8+ T CELLS IN PERIPHERAL BLOOD FROM RHEUMATIC1HEART DISEASE PATIENTS. F Carrión, M Fernandez, LE Coelho Andrade, M Odete-Hilário, FFigueroa. (CHILE-BRAZIL/CHILE-BRASIL). fcarrion@uandes.cl11. DIABETOGENIC EFFECT OF CORN, RICE, BABASSU AND CASSAVA FLOUR. CJ Carvalho-1Filho, EBS Barroqueiro, MVV Lima, NN Guedelha, FRF Nascimento, RNM Guerra.(BRAZIL/BRASIL). cienciasaude@ufma.br12. ANERGY AND APOPTOSIS OF ENCEPHALITOGENIC T LYMPHOCYTES IN EXPERIMENTAL1AUTOIMMUNE ENCEPHALOMYELITIS. AS Farias, DEM Hallal, BM Díaz-Bardales, SR Mirandola,LMB Santos. (BRAZIL/BRASIL). a973186@dac.unicamp.br13. IL-1 beta, IFN gamma, IL-10 EXPRESSION IN PLACENTAL TISSUES OF PATIENTS WITHRHEUMATOID ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS. G Martínez-Bonilla, JF1Muñoz-Valle, G Orozco-Barocio, G Bernard-Medina, AM Gutiérrez-Chavarin, A Daneri-Navarro, VDelgado-Rizo, J Armendáriz-Borunda, M Vázquez-Del Mercado. (MEXICO).biologiamolecular@hotmail.com14. EXPRESSION OF IL-2, TNF alpha, IFN gamma, IL-4 AND IL-10, METALLOPROTEASE-9 ANDHORMONAL STATUS IN RHEUMATOID ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS1 PREGNANT PATIENTS. JF Muñoz-Valle, M Vázquez-Del Mercado M, T García-Iglesias, GOrozco-Barocio, G Bernard-Medina, G Martínez-Bonilla, BE Bastidas-Ramírez, A Daneri-Navarro,M Bueno-Topete, CR Best-Aguilera, RE Navarro-Hernández, V Delgado-Rizo, J Armendáriz-Borunda. (MEXICO). biologiamolecular@hotmail.com15. ASSOCIATION OF MICA POLYMORPHISM WIHT TYPE I DIABETES RISK IN MEXICAN1FAMILIES. JF Mendoza Rincón, O Partida Rodríguez, I Soto Cruz, A García del Valle, B WeissSteider.(MÉXICO). coco2_k1@hotmail.com16. AUTOANTIBODY DETECTION IN CHILDHOOD AUTISM. A PRELIMINARY REPORT. N Montiel,M Zavala. (VENEZUELA). nolam@luz.ve, nolam@cantv.net

17. EXPRESSION OF IL4, IFN-GAMMA AND CD69 IN T LYMPHOCYTES OF PATIENTS WITH1SPONDYLOARTHROPATHIES. I Girón-Pérez, Y Ortega-Ortega, R Burgos-Vargas, E García-Latorre, L Domínguez-López. (MEXICO). ivan_giron@hotmail.com18. IL-13 RECEPTOR IN PSORIATIC KERATINOCYTES: OVER-EXPRESSION OF THE mRNA AND1 UNDER-EXPRESSION OF THE PROTEIN. J Cancino-Díaz, E Reyes-Maldonado, L Jiménez-Zamudio, E García-Latorre, G León-Dorantes, F Blancas-González, M Cancino-Díaz. (MEXICO)Email: mcancino@encb.ipn.mx19. LYMPHOCYTE ACTIVATION FROM PSORIATIC PATIENTS BY RECOMBINANT HEAT SHOCK1 PROTEINS OF Streptococcus pyogenes. A. Pablo-Velázquez, M. Sánchez-Becerra, L.Domínguez-López, E. García-Latorre, L. Jiménez-Zamudio, G. León-Dorantes, M. Cancino-Díaz.(MEXICO). angie_pvelaz@yahoo.com.mx20. PREVALENCE AND ISOTYPE DISTRIBUTION OF ANTIPHOSPHOLIPID ANTIBODIES IN2 UNSELECTED CHILEAN PATIENTS WITH VENOUS AND ARTERIAL THROMBOSIS. Iván Palomo,Jaime Pereira, Marcelo Alarcón, Marcela Vásquez, Carmen Pinochet, María T. Vélez, JorgeSandoval, Gloria Icaza, Silvia Pierangeli. (CHILE-USA / CHILE-EEUU). ipalomo@utalca.cl21. MANAGEMENT OF IMMUNE DISFUNCTIONS IN RESPIRATORY INFECTIONS IN PEDIATRICS2PATIENTS. C.M. Santos Lagresa, M.N. Santos Lagresa, J. Galvez Varcarzel, M. Paredes, J.Corzo. (CUBA).22. HLA-B27 AND ANQUILOSYNG SPONDILITYS ASSOCIATION IN CUBAN POPULATION. Adriana2Artiles, Flora Calzadilla, Lizette Bonet, Raul Ferreira, Aracelys Chico, Elena Kokuina. (CUBA).kokuin@infomed.sld.cu23. AUTOIMMUNE FEATURES IN SUBJECTS WITH SEVERE CORONARY ATHEROSCLEROSIS. Flor2de la C. Heres, Elena Kokuina, Josanne Soto, M. Beatriz Cabalé, Omar González , RobertoLlerena, Lorenzo Llerena. (CUBA). invcar@infomed.sld.cu24. BEHAVIOUR OF THE CONCENTRATION OF IGG IN THE CEREBROSPINAL FLUID (CSF) IN2 PATIENTS WITH SUSPECT OF DESMIELINIZANTES DISEASES OF THE CENTRAL NERVOUSSYSTEM (CNS). I Marten Powell, O. Gámez Rodriquez, E. Lay Georfe (CUBA).Isabel@hospclin.scu.sld.cu25. ANTIPHOSPHOLIPID SYNDROME: INFLUENCE OF SERUM COFACTORS IN THE REACTIVITYOF ANTICARDIOLIPIN ANTIBODIES. L. Muñoz, A. Griego, D. Mendoza. (CUBA).26. FUNCTIONAL SUBSETS OF T CELLS IN THREE AUTOIMMUNE DISEASES. Góngora L, CoronaZ, Jorge C, Lahera R.(CUBA). ledia@labex.scu.sld.cu27. DEVELOPMENT OF AN ATHEROSCLEROSIS MODEL INDUCED BY ACTIVE WAY OF IMMUNE2 COMPLEX FORMATION IN BALB/CBJ MICE. Lien López Matilla, Liudmila López Matilla, AdonisMontenegro Perdomo, Antonio González Griego, Leysis Mcloock, Aluet Borrego Alvarez, VictorManuel Sosa, José A. Castillo, Leonel Falcón Vilaut. (CUBA). lien@giron.sld.cu28. DEVELOPMENT OF AN ATHEROSCLEROSIS MODEL INDUCED BY PASSIVE WAY OF IMMUNECOMPLEX FORMATION IN BALB/CBJ HEPATITIS B SURFACE ANTIGEN TRANSGENIC MICE.2Liudmila López Matilla, Lien López Matilla, Adonis Montenegro Perdomo, Antonio GonzálezGriego, Victor Manuel Sosa, Leysis Mcloock, José A. Castillo, Leonel Falcón Vilaut. (CUBA).liudmila@ict.cim.sld.cu29. HANDLING OF DISIMMUNITARY STATES IN RELATION WITH OCULAR DISEASE. M.N. SantosLagresa, D. Vilches Lescaille, C.M. Santos Lagresa, T. Serrano. (CUBA).30. CSF POLYSPECIFIC ANTIBODY RESPONSE IN MULTIPLE SCLEROSIS. MA Robinson-3Agramonte, H Reiber, AJ Dorta-Contreras. (CUBA-GERMANY / CUBA-ALEMANIA).robin@neubas.sld.cu31. ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN PATIENTS WITH RHEUMATOID ARTHRITIS.M.V.Hernandez, A.M.Torres, I.M.Hernandez. (CUBA).32. TOTAL ANTINUCLEAR AND NEURONAL ANTINUCLEAR ANTIBODIES IN PATIENTS WITH3NEUROLOGIC DISEASES. PRELIMINARY STUDY. Odalis Asín Milán, Loida Torrez, Mabel MuñizRamos, Orestes Ponce of León, Roberto Alegre Mendez. (CUBA). oasin@ipk.sld.cu

33. EVALUATION OF THE TOXICITY OF THE HUMANIZED MONOCLONAL ANTIBODY T1HT IN3PATIENTS WITH RHEUMATOID ARTHRITIS. X Hernández, GA King, J Ducongé, L Roque.(CUBA). Xochelt@ict.cim.sld.cu34. LABORATORY AND CLINICS CHARACTERISTIC IN HASHIMOTO'S THYROIDITIS. Y.R.Espinosa, R. Garcia, M.Savigne. (CUBA).35. PREDICTIVE VALUE OF THE ANTINUCLEAR ANTIBODY SCREENING TEST FOR THE PRESENCE3 OF AUTOANTIBODIES TO EXTRACTABLE NUCLEAR ANTIGENS AND TO dsDNA. ElenaKokuina, Isabel Matamoros, Ingrid García, Aracelys Chico, Miguel Estevez. (CUBA).kokuin@infomed.sld.cu36. AUTOIMMUNE HEMOLITIC ANEMIA (AHA). TREATMENT WITH INTACGLOBÍN.PRESENTATION OF A CASE. B. Rodriguez, A. Noda, A. Vidal (CUBA). anoda@unecavar.cu37. RED CELL ALLOANTIBODIES IN CHILDREN WITH SICKLE CELL DISEASE. L Cortina, R López, ABencomo, T. García. (CUBA). lcortina@hemato.sld.cu38. COMPARISON OF THE INTACGLOBIN WITH THE PREDNISONE IN THE TREATMENT OF THE3TROMBOCITOPENIC PURPURE IMMUNOLOGIC (TPI). A. Noda, A. Vidal, B. Rodríguez (Cuba).E-mail anoda@unecavar.cu39. INTACGLOBIN. THERAPEUTIC ALTERNATIVE IN THE DISSEMINATED LUPUSERYTHEMATOSUS. R. Alvarez, O. Sosa, M. Victoria. (Cuba)40. PARTICIPATION OF PROLACTIN IN THE LYMPHOCYTES ACTIVATION FROM SYSTEMIC4LUPUS ERITHEMATOSUS PATIENTS. Legorreta-Haquet M.V. et al. (CUBA)fblanco1@terra.com.mx

INSTRUCCIONES PARA LA PRESENTACIÓN DE MANUSCRITOS A VACCIMONITORVacciMonitor es una publicación seriada irregular, dedicada a los temas de las vacunas: prevención de enfermedades, biología molecular,antígenos sintéticos, nuevos inmunógenos, adyuvantes, modelos animales, inmunidad, aplicaciones de desarrollo, pruebas clínicas, pruebas decampo, producción, epidemiología, eficacia, calidad y aspectos regulatorios, etcétera.1. Se admiten manuscritos en español e inglés. Los artículos una vez queestén bajo consideración de Ediciones Finlay no podrán ser enviados aotras revistas, y después de aprobados para su publicación, ésta sereserva todos los derechos de reproducción.2. Se aceptarán preferiblemente artículos originales, trabajos cortos en formade cartas al editor y excepcionalmente trabajos de revisión, los cuales seharán en la mayoría de los casos por invitación del Comité Editorial.3. Los trabajos se presentarán en disquetes (preferiblemente en Word) yadjunto un impreso como mínimo de la versión manuscrita.4. Las tablas, gráficos y figuras, con sus leyendas y títulos, deberán estarinsertados en Word y poseer cierto grado de profesionalidad. Se admitenfotos en B/N y color.5. En general el texto no debe exceder de 15 páginas, incluyendo tablas,gráficos y fotos, con un formato de 81/2 x 11, un interlineado de 1,5 ó 2espacios, un puntaje tipográfico de 12, márgenes de 2,5 cm y el tipo depárrafo americano (sin sangría).6. El Comité Editorial de VacciMonitor aceptará o rechazará los originales enfunción de las recomendaciones de los árbitros, su calidad científica y suidoneidad para la revista. Estos revisarán los trabajos y harán losseñalamientos de contenido que estimen convenientes, los cuales serándevueltos a sus autores para sus consideraciones y correcciones.Igualmente, en los manuscritos aceptados se realizarán las modificacioneseditoriales que se estimen necesarias, las cuales serán consultadas consus autores, siempre que sea factible. El autor devolverá el trabajo yacorregido en un plazo no mayor de dos meses; de no ser así el trabajo seráautomáticamente cancelado.7. La autoría y coautoría será confirmada por escrito y firmada por cadamiembro del colectivo.8. El título se escribirá con mayúsculas y minúsculas y contendrá el menornúmero posible de palabras.9. El nombre de los autores y su primer apellido se escribirán completos.10. Las reglas para citar la filiación son sencillas: poner la institución o centro,con su dirección, incluyendo el país. Se citarán en el mismo orden de losautores, utilizando para esto los superíndices ( 1; 2; 3 ; etcétera).11. El resumen deberá aparecer en español e inglés y contener los elementosprincipales del trabajo en forma resumida (unas 250 palabras comomáximo).12. Debajo de cada resumen se incluirán las palabras claves (un máximo deseis).13. En el texto del artículo las referencias se numerarán consecutivamente, connúmeros arábigos entre paréntesis, sin superíndices, de la manerasiguiente: "Se ha observado (3, 4) que..." O bien: "Varios autores (1-5) hanseñalado...". En ese mismo orden se agruparán al final del trabajo. Empleeel estilo de los ejemplos que aparecen más adelante, los cuales estánbasados en las Normas Vancouver, que a su vez es el formato queutilizan en la Biblioteca Nacional de Medicina de los Estados Unidos en elIndex Medicus.14. Absténgase de utilizar los resúmenes como referencias, tampoco lo hagacon las Observaciones inéditas y las Comunicaciones personales. Encambio, se puede insertar en el texto (entre paréntesis) las referencias acomunicaciones escritas, no verbales. Asimismo, incluya en las referenciaslos artículos aceptados, aunque todavía no estén publicados; en este casoindique el título de la revista y agregue "En prensa". La información sobremanuscritos presentados a una revista, pero que aún no han sidoaceptados, cítela en el texto como Observaciones inéditas (entreparéntesis).15. Los autores verificarán las referencias cotejándolas contra los documentosoriginales.A continuación se presentan algunos ejemplos de formas correctas dereferencias.Artículo ordinario:Inclúyase el nombre de todos los autores cuando sean menos de seis; si sonmás de siete, anótese la continuación et al o y otros; título del artículo; nombrecompleto de la revista (en cursiva); año; volumen; número del ejemplar (entreparéntesis); y páginas inicial y final. Toda la información se presentará en ellenguaje original del trabajo citado.Guimaraes MC, Castilho EA, Celeste BJ, Nakahara OS, Amato Netto V.Almacenamiento a largo plazo de IgG e IgM en papel filtro para su uso enencuestas seroepidemiológicas de enfermedades parasitarias. Boletín de laOficina Sanitaria Panamericana. 1986; 100(1):129-144.Libros y otras monografías:Se incluirán los apellidos e iniciales de todos los autores (o editores,compiladores, etc.), o el nombre completo de una entidad colectiva; título (encursiva); número de la edición; lugar de publicación, entidad editorial y año.Cuando proceda se agregarán los números del volumen y páginas consultadas,serie a que pertenece y número que le corresponde en la serie.Colson JH, Armour WJ. Vacunas en el siglo XX. Barcelona: Ediciones Doyma;1990.Capítulo de un libro:Soler C, Marchik EC. Pruebas de laboratorio para detectar infección por VIH. En:Ruiz GM, López H. SIDA, Ciencia y Sociedad. México: Fondo de CulturaEconómica; 1989:103-117.Autor corporativo:España, Ministerio de Sanidad y Consumo. Alcohol y juventud. Madrid: Ministeriode Sanidad y Consumo; 1991.Actas publicadas de congresos, simposios, conferencias:Organización Panamericana de la Salud. Informes finales: 104ª y 105ªReuniones del Comité Ejecutivo de la OPS; XXIII Conferencia SanitariaPanamericana; XLII Reunión, Comité Regional de la OMS para las Américas.Washington DC, OPS, 1990. (Documento oficial 238).Artículo presentado a una conferencia:Harley NH. Comparing radon daughter dosimetric and risk models. In: GammageRB, Kaye SV, eds. Indoor air and human health: proceedings of the Seventh LifeSciences Symposium, Knoxville, Tennessee, October 29-31, 1984. Chelsea,Michigan: Lewis; 1985:69-78.Tesis doctoral:Youssef NM. School adjustment of children with congenital heart disease[dissertation]. Pittsburgh (PA): Univ of Pittsburgh; 1988.Patente:Harred JF, Knight AR, Mcllntyre JS, inventors. Dow Chemical Company,assignee. Expoxidation process. US patent 3,654,317. 1972 Apr 4.