FGF-signalling in the differentiation of mouse ES cells towards ...
FGF-signalling in the differentiation of mouse ES cells towards ...
FGF-signalling in the differentiation of mouse ES cells towards ...
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<strong>FGF</strong>R(IIIc)-activation <strong>in</strong>duces mesendoderm but isdispensable for def<strong>in</strong>itive endoderm formation <strong>in</strong> <strong>mouse</strong>embryonic stem <strong>cells</strong>Janny Marie L. Peterslund and Palle Serup*Department <strong>of</strong> Stem Cell Biology, Hagedorn Research Institute, Niels Steensens Vej 6, DK-2820 Gent<strong>of</strong>te, Denmark.Runn<strong>in</strong>g title: <strong>FGF</strong>(R)s and mesendoderm <strong>differentiation</strong> <strong>in</strong> m<strong>ES</strong>CsKeywords: <strong>mouse</strong> embryonic stem cell, fibroblast growth factor (<strong>FGF</strong>), <strong>FGF</strong> receptors,mesendoderm, def<strong>in</strong>itive endoderm, <strong>FGF</strong>4 –/– cell l<strong>in</strong>e*Correspond<strong>in</strong>g author:Dr. Palle SerupHagedorn Research InstituteNiels Steensens Vej 6DK-2820 Gent<strong>of</strong>teDenmarkE-mail: pas@hagedorn.dkPhone: +45 44439822Fax: +45 4443800058