Part 6: Detection and Prevention of Foot Problems in Type 2 Diabetes
Part 6: Detection and Prevention of Foot Problems in Type 2 Diabetes Part 6: Detection and Prevention of Foot Problems in Type 2 Diabetes
Summary - Peripheral Vascular Disease as a Risk Factor• Peripheral vascular disease is common in people with Type 2 diabetes• Peripheral vascular disease is associated with a 2-4 fold increased risk ofamputation• The role of peripheral vascular disease as a independent risk factor for footulceration remains uncertain24
Evidence Table: Section 2AuthorPeripheral vascular disease as a risk factorLevel of EvidenceLevel Study TypeEvidenceQualityRatingMagnitudeRatingRelevanceRatingAbbott C (2002)(Adults – UK)III-2 Cohort High High + HighAdler AI (1999)(Adults – US)III-2 Cohort High High + HighBoyko EJ (1999)(Adults – US)III-2 Cohort High High + Highdel Aguila MA (1994)(Adults – US)III-2 Case-control Medium High + HighHamalainen H (1999)(Adults – Finland)III-2 Cohort High High + HighLavery LA (1998)(Adults – US)III-2 Case-control High High + HighLehto S (1996)(Adults – Finland)III-2 Cohort High High + HighMayfield JA (1996)(Adults – US: Gila River III-2 Case-control High High + LowIndians)McNeely MJ (1995)(Adults – US)III-2 Case-control High High + HighMoulik PK (2003)(Adults – UK)III-2 Cohort High High + HighPham H (2000)(Adults – US)III-2 Cohort High High + HighReiber GE (1999)(Adults – US; UK)III-2 Cohort Medium Low HighRith-Najarian S (1992)Adults – US: Red Lake III-2 Cohort High High + LowChippewa IndiansFor magnitude rating:+peripheral vascular disease is a risk factor for diabetic foot disease. High = clinically important & statistically significant;Medium = small clinical importance & statistically significant; Low = no statistically significant effect.Criteria for Quality and Relevance ratings are detailed in Appendix 9.25
- Page 1: National Evidence Based Guidelinesf
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- Page 12 and 13: Background - Peripheral Neuropathy
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- Page 46 and 47: Evidence Table: Section 5Detection
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- Page 56 and 57: Summary - Frequency of Foot Examina
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Summary - Peripheral Vascular Disease as a Risk Factor• Peripheral vascular disease is common <strong>in</strong> people with <strong>Type</strong> 2 diabetes• Peripheral vascular disease is associated with a 2-4 fold <strong>in</strong>creased risk <strong>of</strong>amputation• The role <strong>of</strong> peripheral vascular disease as a <strong>in</strong>dependent risk factor for footulceration rema<strong>in</strong>s uncerta<strong>in</strong>24
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