QUESTIONS KEY WORDS NO.ARTICLESIDENTIFIED1. Is peripheralneuropathy a riskfactor forulceration oramputation?Diabetic neuropathy/ co,dm,rh,si,ep AND (diabetic foot/et,co,pc,di,rh,dm,ep,th OR sk<strong>in</strong>ulcer/ pc,co,rh,di,si,ep,th, et ORamputation/ OR below kneeamputation/ OR foot deformities,acquired/ OR foot amputation/OR keratosis.mp OR limbamputation/) EM 88-99171NO.RELEVANTARTICLES26ARTICLESIDENTIFIED BYOTHERSTRATEGIESTOTAL FORREVIEWLEVEL I LEVEL II LEVELIIILEVEL IV TOTAL NO.REVIEWED &GRADEDHIGHESTLEVEL OFEVIDENCEDiabetic neuropathy/ co,dm,rh,si,ep AND (diabetic foot/et,co,pc,di,rh,dm,ep,th OR sk<strong>in</strong>ulcer/ pc,co,rh,di,si,ep,th, et ORbelow knee amputation/ OR footamputation/ OR keratosis.mp ORlimb amputation/) EM 99-0316932Diabetic foot/ AND diabeticneuropathies/ CO216Diabetic foot/ AND risk factors/CO1262. Is peripheralvascular disease arisk factor forulceration oramputation?<strong>Diabetes</strong> mellitus/ AND riskfactors/ COTotal for Question 2PVD/ AND (sk<strong>in</strong> ulcer/ ORcallus/ OR amputation/ ORdiabetic foot/) M, CIPVD/ AND (sk<strong>in</strong> ulcer/ OR footdeformities, acquired/ ORkeratosis/ OR amputation/ ORdiabetic foot/) M 66-99, CI64174354 (M)57 (CI)117 (M)57 (CI)21851(M)17 (CI)6 (M)10 (CI)64 106 1 3 22 5 31 IPVD/ AND (sk<strong>in</strong> ulcer/ ORcallus.mp OR amputation/ ORdiabetic foot/ OR keratosis/ ORfoot deformities, acquired/) M 99-027611+PVD/ AND (sk<strong>in</strong> ulcer/ OR bonycallus/ OR amputation/ ORdiabetic foot/ OR keratosis/ ORfoot deformities, acquired/) M 03-04211128
QUESTIONS KEY WORDS NO.ARTICLESIDENTIFIED2. Is peripheralvascular disease arisk factor forulceration oramputation?PVD/ AND (sk<strong>in</strong> ulcer/ ORcallus/ amputation/ OR diabeticfoot/ OR foot deformities,acquired/ OR keratosis/) CI 99-04Risk factors/ AND diabetic foot/M 66-04, CI 82-0454402 (M)114 (CI)NO.RELEVANTARTICLES1161 (M)30 (CI)ARTICLESIDENTIFIED BYOTHERSTRATEGIESTOTAL FORREVIEWLEVEL I LEVEL II LEVELIIILEVEL IV TOTAL NO.REVIEWED &GRADEDHIGHESTLEVEL OFEVIDENCEPVD/co,pc,rh,si,ep,et, AND (sk<strong>in</strong>ulcer/pc,co,rh,di,si,ep,th,et ORkeratosis.mp OR below kneeamputation/ OR foot deformitiesacquired/ OR amputation/ ORdiabetic foot/ OR limbamputation/) EMRisk factors/ep,co,et,di,pc,siAND diabetes mellitus/ co,rh,si,ep EMPeripheral vascular disease/ AND(amputation/ OR foot amputation/OR below knee amputation/ ORleg amputation/ OR foot ulcer/OR sk<strong>in</strong> ulcer/ OR keratosis/ ORdiabetic foot/) EM 99-04Diabetic foot/ AND risk factors/CO<strong>Diabetes</strong> mellitus/ AND riskfactors/ CO679601961214923108613129
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National Evidence Based Guidelinesf
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Research OfficersMs Linda SmithPodi
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2.2 Issues for Foot Problems in Typ
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• Aim to achieve the best possibl
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Background - Peripheral Neuropathy
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proportion of subjects with a durat
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and an OR 1.1-7.8. This study also
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Summary - Peripheral Neuropathy as
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Section 2: Diabetes Foot ProblemsIs
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predicting risk of amputation, 2.9
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Summary - Peripheral Vascular Disea
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Section 3: Diabetes Foot ProblemsIs
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Evidence - Foot Deformity and Previ
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people with both LJM and neuropathy
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Summary - Foot Deformity and Previo
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Section 4: Diabetes Foot ProblemsIs
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Also in the Seattle study, 67 peopl
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Summary - Ulcer as a Risk Factor fo
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Section 5: Diabetes Foot ProblemsIs
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The other frequently reported metho
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side; and 82% having the same resul
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Evidence Table: Section 5Detection
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Background - Clinical Detection of
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pulse was bilaterally absent in 1.8
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Evidence Table: Section 6AuthorClin
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Background - Frequency of Foot Exam
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Summary - Frequency of Foot Examina
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Section 8: Diabetes Foot ProblemsIs
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Behaviour assessment scores, measur
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Mazzuca et al (1986) studies 532 pe
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with before the programme, after 1-
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Evidence Table: Section 8AuthorEffe
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Background - Glycaemic Control and
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In a previous Japanese randomised s
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Evidence Table: Section 9AuthorGlyc
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Background - Footwear to Reduce Ulc
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period. In addition people without
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