Lecture 2 - Center for Biomedical Optics and New Laser Systems

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M = M tissueM std= S T tissueG tissueDS T stdG stdD€delivery <strong>and</strong> collectionfibers contact surface...= T tissueG tissueT stdG std= T tissuecalib€cannot know T stdwithout knowing optical properties of st<strong>and</strong>ard
Non-diffusive light transportexamples:Confocal microscopy (CM)Optical coherence microscopy (OCT)
Page 2: Consider a cup of coffee with cream
Page 8 and 9: R ≈ e −µ a Ladd a drop ofabsor
Page 10 and 11: Measurement vs properties gridColle
Page 12 and 13: lack x = µ s ’ < 10µ ablue = co
Page 16 and 17: µ a = 0.1 cm -1
Page 18 and 19: µ a = 0.1 cm -1
Page 20 and 21: µ a = 0.1 cm -1
Page 22 and 23: Oblique R(r)Light is delivered at a
Page 26 and 27: CameraBeam of lightM total.std exam
Page 28 and 29: mua = 0.1mua = 0
Page 30 and 31: mua = 0.5mua = 0
Page 32 and 33: R std M total M total.std RM total
Page 34 and 35: Added absorber methodDetector sense
Page 36 and 37: Added absorber methodBeam of lightD
Page 42 and 43: 10.90.8blue = const µ s', red = co
Page 44 and 45: R total + added absorber10.90.80.70
Page 46 and 47: M = M tissueM std= S T tissueG tiss
Page 48 and 49: M = M tissueM std= S T tissueG tiss
Page 52: Reflectance-mode ConfocalMicroscopy
Page 55 and 56: Coherence gate of OCT provides a 45
Page 57 and 58: ρe −µz€~1/1000 thCMOCT
Page 59 and 60: R(z)€ρ = local reflectivity [-]
Page 61 and 62: T inT out= e −a(g)µ s z f 2Gag
Page 63 and 64: R = T inρT out= ρe −µz f= µ s
Page 65: Mietheory
Page 68 and 69: Consider a rCLSM or OCT image…
Page 70 and 71: Consider a rCLSM or OCT image…R(z
Page 75 and 76: perturbationnormal
Page 77 and 78: Osteogenesis Mouse imperfecta skino
Page 79 and 80: RickyWangIn vivo optical properties
Page 81 and 82: Smooth muscles cells cause the scat
Page 83 and 84: ρ [dimensionless]RobertMcLaughlinU
Page 85: Tissue OpticsSteven L. Jacquesjacqu

Lecture 2 - Center for Biomedical Optics and New Laser Systems

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