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TOXICOLOGICAL PROFILE FOR CHROMIUM - Davidborowski.com

TOXICOLOGICAL PROFILE FOR CHROMIUM - Davidborowski.com

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TABLE 2-1. Levels of Significant Exposure to Chromium - InhalationLOAELExposure/Key to a Species duration/NOAEL Less serious Serious Reference/figure (strain) frequency System (mg Cr/m3) (mg Cr/m3)(mg Cr/m3)FormACUTE EXPOSUREDeath1 Rat 4 hr2(Fischer- 344)Rat 4 hr(Fischer- 344)Rat 4 hr(Fischer- 344)4 Rat 4 hr(Fischer- 344)5 Rat 4 hr(Fischer- 344)Systemic6 Hamster 30 min Resp 0.9 (increased acid(Syrian)phosphatase activity inlung tissue)137 M (LC 50)87 F (LC 50)33(LC 50)82 M (LC 50)45 F (LC 50)35 M (LC 50)29 F (LC 50)70 M (LC 50)31 F (LC 50)American Chromeand Chemical1989CrO 3(VI)Gad et al. 1986Na 2CrO 4(VI)Gad et al. 1986(NH 4) 2Cr 2O (VI) 7Gad et al. 1986Kr 2Cr 2O (VI) 7Gad et al. 1986Na 2Cr 2O 2H 7 2O (VI)Henderson et al.1979CrCI (III) 32. HEALTH EFFECTS<strong>CHROMIUM</strong> 18

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