TOXICOLOGICAL PROFILE FOR CHROMIUM - Davidborowski.com

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CHROMIUM 3327. REGULATIONS AND ADVISORIESTable 7-1. Regulations and Guidelines Applicable to Chromium (continued)Agency Description Information ReferenceNATIONAL (cont.)EPABiological exposure indices—Chromium (VI)Total chromium in urineIncrease during shiftEnd of shift and weekChromium(III)RfD (oral)RfCCancer classificationChromium(VI)RfD (oral)Oral cancer classificationCarcinogenic risk frominhalation exposureInhalation cancerclassificationToxic chemical releasereporting—effective dateReportable quantities ofhazardous substancesChromium—designatedCERCLA hazardoussubstance under sections307(a) of the Clean WaterActChromicacetate—designatedCERCLA hazardoussubstance under sections311(b)(4) of the CleanWater ActChromic sulfate—designated CERCLAhazardous substance undersections 311(b)(4) of theClean Water ActChromic acid—designatedCERCLA hazardoussubstance under sections311(b)(4) of the CleanWater Act10 µg/g creatinine30 µg/g creatinine1.5 mg/kg/dayNot availableD-not classified3x10 -3 mg/kg/dayD—not classified1.2x10 -2 µg/m 3A—known humancarcinogenACGIH 1999IRIS 2000aIRIS 2000b1/1/87 40 CFR 372.65EPA 1999a5,000 pounds1,000 pounds1,000 pounds10 pounds40 CFR 302.4EPA 1999d
CHROMIUM 3337. REGULATIONS AND ADVISORIESTable 7-1. Regulations and Guidelines Applicable to Chromium (continued)Agency Description Information ReferenceNATIONAL (cont.)Calcium chromate—designated CERCLAhazardous substance undersections 311(b)(4) of theClean Water Act and RCRAsection 300110 poundsDHHSCarcinogen classificationchromium and certainchromium(VI) compounds(calcium chromate, chromiumtrioxide, lead chromate,strontium chromate, and zincchromate)Known humancarcinogensNTP 1989, 1991,1992, 1998STATERegulations andGuidelines:a. Air:IdahoKansasChromium(VI)Acceptable ambientconcentration for acarcinogenChromium, chromium(I), andchromium(III)Acceptable concentrationoccupational exposure levelConcentration limits forhazardous air emissions:chromium andchromium(III)chromium(VI)ID Dept Health8.3x10 -5 µg/m 3Welfare 1999b0.025 mg/m 30.5 mg/m 35 tons/year0.002 tons/yearKS Dept. HealthEnv 1998KentuckySignificant emission levelChromium metal,chromium(II), andchromium(III)Calcium chromate, leadchromate, lead chromateoxide, and zinc chromatechromium(VI)1.276x10 -4 pounds/hour1.276x10 -5 pounds/hour2.76x10 -6 pounds/hourKY Div Air Quality1998LouisianaAllowable emission ratechromium(VI)25 pounds/year LA Air Quality Div1998
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TOXICOLOGICAL PROFILE FORCHROMIUMU.
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CHROMIUMiiiUPDATE STATEMENTToxicolo
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CHROMIUMviiQUICK REFERENCE FOR HEAL
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CHROMIUMxiPEER REVIEWA peer review
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CHROMIUMxiv2.2.3.1 Death ..........
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CHROMIUMxviC. ACRONYMS, ABBREVIATIO
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CHROMIUM 11. PUBLIC HEALTH STATEMEN
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CHROMIUM 121. PUBLIC HEALTH STATEME
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CHROMIUM 142. HEALTH EFFECTSessenti
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CHROMIUM 162. HEALTH EFFECTSuncerta
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TABLE 2-1. Levels of Significant Ex
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11 Rat 90 d Resp 0.025 M (increased
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20 Rat(Wistar)Reproductive90 d7 d/w
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33 Rat I8 mo Resp 0.1 M Glaser et a
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43 Human44 Human45 Human46 Human47
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forFigure 2-1. Levels of Significan
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35r 35r 35r 35r 35r 35r 35r 35r 35r
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CHROMIUM 322. HEALTH EFFECTSInterme
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CHROMIUM 342. HEALTH EFFECTSexposur
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CHROMIUM 362. HEALTH EFFECTSsulfate
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CHROMIUM 382. HEALTH EFFECTScorrela
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CHROMIUM 402. HEALTH EFFECTS1953).
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CHROMIUM 422. HEALTH EFFECTSBaltimo
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CHROMIUM 442. HEALTH EFFECTSHepatic
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CHROMIUM 462. HEALTH EFFECTSdichrom
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CHROMIUM 482. HEALTH EFFECTSdamage
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CHROMIUM 502. HEALTH EFFECTSChromiu
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CHROMIUM 522. HEALTH EFFECTSAn exte
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CHROMIUM 542. HEALTH EFFECTS2.2.1.7
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CHROMIUM 562. HEALTH EFFECTS2.2.1.8
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CHROMIUM 582. HEALTH EFFECTSmajor p
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CHROMIUM 602. HEALTH EFFECTSfound a
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CHROMIUM 622. HEALTH EFFECTSsignifi
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CHROMIUM 642. HEALTH EFFECTSheavy s
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CHROMIUM 662. HEALTH EFFECTScarcino
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CHROMIUM 682. HEALTH EFFECTS(female
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CHROMIUM 702. HEALTH EFFECTSFerroch
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CHROMIUM 722. HEALTH EFFECTS1.2x10
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CHROMIUM 742. HEALTH EFFECTSchromiu
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8 Rat once 26 M (LD 50)(Fischer- 34
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20 Mouse 9 d Bd Wt 53.2 F 101 .1 F
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32 Rat(BD)33 RatSwiss albino34 RatD
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Neurological45 Rat 28 d(Wistar)Repr
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59 Mouse 85 d + 36.7 F NTP 1997(BAL
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CHRONIC EXPOSURESystemic70 Human71
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Figure 2-2. Levels of Significant E
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MinimalFigure 2-2. Levels of Signif
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CHROMIUM 922. HEALTH EFFECTSand blo
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CHROMIUM 942. HEALTH EFFECTSHematol
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CHROMIUM 962. HEALTH EFFECTSAverage
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CHROMIUM 982. HEALTH EFFECTSchanges
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CHROMIUM 1002. HEALTH EFFECTSsperma
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CHROMIUM 1022. HEALTH EFFECTSchromi
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CHROMIUM 1042. HEALTH EFFECTS2.2.2.
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CHROMIUM 1062. HEALTH EFFECTSImpair
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CHROMIUM 1082. HEALTH EFFECTSrates
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TABLE 2-3. Levels of Significant Ex
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HumanHumanHumanHumanHumanHumanHuman
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CHRONIC EXPOSURESystemicHuman 7.5 y
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CHROMIUM 1162. HEALTH EFFECTSNo stu
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CHROMIUM 1182. HEALTH EFFECTSIrrita
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CHROMIUM 1202. HEALTH EFFECTSindust
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CHROMIUM 1222. HEALTH EFFECTSGuinea
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CHROMIUM 1242. HEALTH EFFECTSmodel,
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CHROMIUM 1262. HEALTH EFFECTSblood,
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CHROMIUM 1302. HEALTH EFFECTSAlthou
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CHROMIUM 1322. HEALTH EFFECTS2.3.2
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CHROMIUM 1362. HEALTH EFFECTSThe di
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CHROMIUM 1382. HEALTH EFFECTS(2-5 m
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CHROMIUM 1402. HEALTH EFFECTSIn rat
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CHROMIUM 1422. HEALTH EFFECTSunstab
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CHROMIUM 1442. HEALTH EFFECTSIn add
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CHROMIUM 1462. HEALTH EFFECTSsignif
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CHROMIUM 1502. HEALTH EFFECTSDaily
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CHROMIUM 1522. HEALTH EFFECTS51 Chr
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CHROMIUM 1562. HEALTH EFFECTSFigure
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CHROMIUM 1582. HEALTH EFFECTSTable
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CHROMIUM 1622. HEALTH EFFECTSInterr
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CHROMIUM 1642. HEALTH EFFECTSthe bl
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CHROMIUM 1662. HEALTH EFFECTSpreval
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CHROMIUM 1682. HEALTH EFFECTS2.5 RE
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CHROMIUM 1702. HEALTH EFFECTSSevera
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CHROMIUM 1722. HEALTH EFFECTSanimal
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CHROMIUM 1742. HEALTH EFFECTSOral M
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CHROMIUM 1762. HEALTH EFFECTSfibros
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CHROMIUM 1782. HEALTH EFFECTSNausea
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CHROMIUM 1802. HEALTH EFFECTSthe pr
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CHROMIUM 1822. HEALTH EFFECTSSevere
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CHROMIUM 1842. HEALTH EFFECTSdevelo
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CHROMIUM 1862. HEALTH EFFECTSthe ce
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CHROMIUM 1882. HEALTH EFFECTSimprov
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CHROMIUM 1902. HEALTH EFFECTSchroma
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CHROMIUM 1922. HEALTH EFFECTSIn ano
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Table 2-5. Genotoxicity of Chromium
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Table 2-5. Genotoxicity of Chromium
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Species (test system)Prokaryotic or
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Species (test system)S. typhimurium
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Species (test system)Mouse A18BcR c
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Species (test system)Prokaryotic or
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Species (test system)Syrian hamster
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CHROMIUM 2082. HEALTH EFFECTSet al.
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CHROMIUM 2102. HEALTH EFFECTScancer
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CHROMIUM 2122. HEALTH EFFECTS2.6 EN
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CHROMIUM 2142. HEALTH EFFECTSChromi
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CHROMIUM 2182. HEALTH EFFECTSBiolog
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CHROMIUM 2222. HEALTH EFFECTSemploy
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CHROMIUM 2242. HEALTH EFFECTSunexpe
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CHROMIUM 2262. HEALTH EFFECTSMutti
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CHROMIUM 2282. HEALTH EFFECTS1986a,
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CHROMIUM 2302. HEALTH EFFECTSconcen
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CHROMIUM 2322. HEALTH EFFECTSmentio
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CHROMIUM 2362. HEALTH EFFECTSglutat
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CHROMIUM 2382. HEALTH EFFECTS1997).
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CHROMIUM 2402. HEALTH EFFECTS
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CHROMIUM 2422. HEALTH EFFECTSlimite
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CHROMIUM 2442. HEALTH EFFECTSThe re
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CHROMIUM 2462. HEALTH EFFECTS(Nette
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CHROMIUM 2482. HEALTH EFFECTSsperma
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CHROMIUM 2502. HEALTH EFFECTSThere
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CHROMIUM 2522. HEALTH EFFECTStimesp
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CHROMIUM 2542. HEALTH EFFECTSShmito
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CHROMIUM 2562. HEALTH EFFECTShas no
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CHROMIUM 2582. HEALTH EFFECTSTable
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CharacteristicSynonym(s)Table 3-1.
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CHROMIUM 2663. CHEMICAL AND PHYSICA
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CHROMIUM 2744. PRODUCTION, IMPORT/E
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Page 301 and 302: CHROMIUM 2815. POTENTIAL FOR HUMAN
Page 303 and 304: Derived from HazDat 2000Figure 5-2.
Page 307 and 308: State bTable 5-2. Releases to the E
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Page 337 and 338: Sample matrixTable 6-1. Analytical
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Page 341 and 342: Sample matrixOccupational air(weldi
Page 343 and 344: Sample matrixWaste water 1986(chrom
Page 345 and 346: CHROMIUM 3256. ANALYTICAL METHODS6.
Page 347 and 348: CHROMIUM 3277. REGULATIONS AND ADVI
Page 351: CHROMIUM 3317. REGULATIONS AND ADVI
Page 359 and 360: CHROMIUM 3398. REFERENCES*Aaseth J,
Page 361 and 362: CHROMIUM 3418. REFERENCES*Anderson
Page 363 and 364: CHROMIUM 3438. REFERENCES*Baranowsk
Page 365 and 366: CHROMIUM 3458. REFERENCESBlack CB,
Page 367 and 368: CHROMIUM 3478. REFERENCES*Buckell M
Page 369 and 370: CHROMIUM 3498. REFERENCES*Chen NSC,
Page 371 and 372: CHROMIUM 3518. REFERENCESCriqui M,
Page 373 and 374: CHROMIUM 3538. REFERENCESDOD. 1947.
Page 375 and 376: CHROMIUM 3558. REFERENCES*EPA. 1984
Page 377 and 378: CHROMIUM 3578. REFERENCES*EPA. 1996
Page 379 and 380: CHROMIUM 3598. REFERENCESFlint GN,
Page 381 and 382: CHROMIUM 3618. REFERENCES*Gale TF,
Page 383 and 384: CHROMIUM 3638. REFERENCESGriepink B
Page 385 and 386: CHROMIUM 3658. REFERENCES*Hayes RB,
Page 387 and 388: CHROMIUM 3678. REFERENCESHunt CD, S
Page 389 and 390: CHROMIUM 3698. REFERENCES*Jansen LH
Page 391 and 392: CHROMIUM 3718. REFERENCESKeith RL,
Page 393 and 394: CHROMIUM 3738. REFERENCES*Korallus
Page 395 and 396: CHROMIUM 3758. REFERENCES*Laborda R
Page 397 and 398: CHROMIUM 3778. REFERENCESLees PSJ,
Page 399 and 400: CHROMIUM 3798. REFERENCES*Liu KJ, J
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CHROMIUM 3838. REFERENCESMehra R, B
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CHROMIUM 3858. REFERENCES*Morris B,
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CHROMIUM 3878. REFERENCES*Newbold R
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CHROMIUM 3898. REFERENCES*Novey HS,
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CHROMIUM 3918. REFERENCES*OSHA 1999
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CHROMIUM 3938. REFERENCESPiela Z, K
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CHROMIUM 3958. REFERENCESRI Div Air
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CHROMIUM 3978. REFERENCES*Sata F, A
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CHROMIUM 3998. REFERENCES*Sheppard
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CHROMIUM 4018. REFERENCES*Snyder CA
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CHROMIUM 4038. REFERENCESŠtupar J,
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CHROMIUM 4058. REFERENCESTamino G,
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CHROMIUM 4078. REFERENCES*Ueno S, S
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CHROMIUM 4098. REFERENCESWahlberg J
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CHROMIUM 4118. REFERENCES*Wiegand H
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CHROMIUM 4138. REFERENCES*Zhitkovic
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CHROMIUM 4169. GLOSSARYCase Series
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CHROMIUM 4189. GLOSSARYModifying Fa
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CHROMIUM 4209. GLOSSARYeither under
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CHROMIUM A-1APPENDIX AATSDR MINIMAL
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CHROMIUM A-3APPENDIX AMINIMAL RISK
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CHROMIUM A-5APPENDIX AMINIMAL RISK
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CHROMIUM A-7APPENDIX AWas a convers
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CHROMIUM B-2APPENDIX B(2) Exposure
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1SAMPLE6 TABLE 2-1. Levels of Signi
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CHROMIUM B-6APPENDIX BChapter 2 (Se
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CHROMIUM C-1APPENDIX CACRONYMS, ABB
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CHROMIUM C-3APPENDIX CTRITWAU.S.UFy
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