TOXICOLOGICAL PROFILE FOR CHROMIUM - Davidborowski.com

Species (test system)Prokaryotic organisms (cont.):Table 2-7. Genotoxicity of Chromium(III) In Vitro (continued)End pointWithactivationResultsWithoutactivation Reference CompoundE. coli Gene mutations No data + Sugden et al. 1990 cis-Dichlorobis (2,2'-bipyridyl)chromium(III)E. coli AB1157, GC275,VA4202, PQ30Induction of SOSresponseE. coli PQ37, PQ35 Induction of SOSresponseE. coli PQ37 Induction of SOSresponseE. coli PQ37 Induction of SOSresponseSalmonella typhimuriumTA100, TA1535TA98, TA1537, TA1538Reverse mutationsBase pairsubstitutionsFrame shift mutationsS. typhimurium TA102 Base pairsubstitutionsS. typhimuriumTA100, TA1535TA98, TA1538Base pairsubstitutionsFrame shift mutationsNo data – Llagostera et al.1986– – Olivier and Marzin1987Chromium trichloride,chromium nitrate, chromiumacetateChromium trichloridehexahydrate– – Venier et al. 1989 Chromium trichloride,chromium nitrate– (+) Venier et al. 1989 Chromium acetate––––De Flora 1981;Petrilli and De Flora1978b– – Bennicelli et al.1983––––Venier et al. 1982Chromium trichloridehexahydrate, chromiumnitrite, monohydrate,chromium potassium sulfate,chromium acetate,neochromium, chromiumalum, chromiteChromium nitrateChromium chloridehexahydrate, chromiumnitrate monohydrateCHROMIUM 2042. HEALTH EFFECTS