TOXICOLOGICAL PROFILE FOR CHROMIUM - Davidborowski.com

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<strong>CHROMIUM</strong>xviC. ACRONYMS, ABBREVIATIONS, AND SYMBOLS ............................. C-1
Page 1 and 2: TOXICOLOGICAL PROFILE FORCHROMIUMU.
Page 3: CHROMIUMiiiUPDATE STATEMENTToxicolo
Page 7 and 8: CHROMIUMviiQUICK REFERENCE FOR HEAL
Page 11: CHROMIUMxiPEER REVIEWA peer review
Page 14 and 15: CHROMIUMxiv2.2.3.1 Death ..........
Page 20 and 21: CHROMIUMxxLIST OF TABLES2-1 Levels
Page 22 and 23: CHROMIUM 21. PUBLIC HEALTH STATEMEN
Page 31 and 32: CHROMIUM 111. PUBLIC HEALTH STATEME
Page 33 and 34: CHROMIUM 132. HEALTH EFFECTS2.1 INT
Page 35 and 36: CHROMIUM 152. HEALTH EFFECTSconside
Page 37 and 38: CHROMIUM 172. HEALTH EFFECTSin both
Page 39 and 40: INTERMEDIATE EXPOSURESystemic7 Huma
Page 41 and 42: 15 Rabbit 4-6 wk Resp 0.6 M (decrea
Page 43 and 44: 26 Human27 Human28 Human29 Human0.2
Page 45 and 46: 36 Rat 2 yr Resp 1.6 (granulomata,
Page 47 and 48: 51 Mouse 18 rno(C57BL/6) 5 d/wk5 hr
Page 49 and 50: 0In0sc z14m13m16h15h12r12r12r10r 11
Page 51 and 52: ~ ~-Figure 2-1. Levels of Significa
Page 53 and 54: CHROMIUM 332. HEALTH EFFECTSexcessi
Page 55 and 56: CHROMIUM 352. HEALTH EFFECTShad per
Page 57 and 58: CHROMIUM 372. HEALTH EFFECTSmedical
Page 59 and 60: CHROMIUM 392. HEALTH EFFECTSchromat
Page 61 and 62: CHROMIUM 412. HEALTH EFFECTSGastroi
Page 63 and 64: CHROMIUM 432. HEALTH EFFECTSengaged
Page 65 and 66: CHROMIUM 452. HEALTH EFFECTSphospho
Page 67 and 68:
CHROMIUM 472. HEALTH EFFECTSferroch
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CHROMIUM 492. HEALTH EFFECTSBody We
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CHROMIUM 512. HEALTH EFFECTSincreas
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CHROMIUM 532. HEALTH EFFECTSThe occ
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CHROMIUM 552. HEALTH EFFECTSwith co
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CHROMIUM 572. HEALTH EFFECTSinclude
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CHROMIUM 592. HEALTH EFFECTSA cohor
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CHROMIUM 612. HEALTH EFFECTSreveale
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CHROMIUM 632. HEALTH EFFECTSchromiu
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CHROMIUM 652. HEALTH EFFECTSIn a st
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CHROMIUM 672. HEALTH EFFECTSan asso
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CHROMIUM 692. HEALTH EFFECTSexamina
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CHROMIUM 712. HEALTH EFFECTStwo fer
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CHROMIUM 732. HEALTH EFFECTScaustic
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TABLE 2-2. Levels of Significant Ex
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Systemic14 Human15 Human16 Human17
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INTERMEDIATE EXPOSUREDeath25 Mouse
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39 Mouse 12wk Bd Wt(Swiss)(W)Bd Wt4
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52 Rat 9 wk(Sprague- (F)Dawley)53 M
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66 Mouse Gd12- 74 (reduced ovary an
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74 Rat 2-3 yr Cardio 0.46(Long- Eva
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forFigure 2-2. Levels of Significan
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Figure 2-2. Levels of Significant E
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CHROMIUM 932. HEALTH EFFECTSvomitin
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CHROMIUM 952. HEALTH EFFECTSchromiu
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CHROMIUM 972. HEALTH EFFECTSProtein
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CHROMIUM 992. HEALTH EFFECTSSplenoc
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CHROMIUM 1012. HEALTH EFFECTSexamin
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CHROMIUM 1032. HEALTH EFFECTSsexual
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CHROMIUM 1052. HEALTH EFFECTSIn the
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CHROMIUM 1072. HEALTH EFFECTSto pot
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CHROMIUM 1092. HEALTH EFFECTSSingle
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Gn pig(NS)Gn pig(NS)Rabbit(NS)Rabbi
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HumanHumanGn pig(albino)Gn pig(albi
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CHROMIUM 1152. HEALTH EFFECTSCardio
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CHROMIUM 1172. HEALTH EFFECTSAcute
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CHROMIUM 1192. HEALTH EFFECTSchromi
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CHROMIUM 1212. HEALTH EFFECTSIn a s
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CHROMIUM 1232. HEALTH EFFECTSdiffus
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CHROMIUM 1252. HEALTH EFFECTSfor zi
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CHROMIUM 1272. HEALTH EFFECTSStudie
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CHROMIUM 1292. HEALTH EFFECTSat app
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CHROMIUM 1312. HEALTH EFFECTSaqueou
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CHROMIUM 1332. HEALTH EFFECTSChromi
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CHROMIUM 1352. HEALTH EFFECTSsource
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CHROMIUM 1372. HEALTH EFFECTSTwelve
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CHROMIUM 1392. HEALTH EFFECTSred bl
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CHROMIUM 1412. HEALTH EFFECTSinject
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CHROMIUM 1432. HEALTH EFFECTScorneu
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CHROMIUM 1452. HEALTH EFFECTSand NA
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CHROMIUM 1492. HEALTH EFFECTSresult
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CHROMIUM 1512. HEALTH EFFECTSRats g
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CHROMIUM 1532. HEALTH EFFECTSinject
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CHROMIUM 1552. HEALTH EFFECTSmany b
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CHROMIUM 1572. HEALTH EFFECTS2.3.5.
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CHROMIUM 1592. HEALTH EFFECTSTable
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CHROMIUM 1612. HEALTH EFFECTSincorp
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CHROMIUM 1632. HEALTH EFFECTSwith t
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CHROMIUM 1652. HEALTH EFFECTSTissue
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CHROMIUM 1672. HEALTH EFFECTSThe pr
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CHROMIUM 1692. HEALTH EFFECTSelevat
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CHROMIUM 1712. HEALTH EFFECTS1 mg c
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CHROMIUM 1732. HEALTH EFFECTSThe re
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CHROMIUM 1752. HEALTH EFFECTSSystem
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CHROMIUM 1792. HEALTH EFFECTSleukoc
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CHROMIUM 1812. HEALTH EFFECTShyperp
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CHROMIUM 1832. HEALTH EFFECTSNecros
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CHROMIUM 1852. HEALTH EFFECTSduring
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CHROMIUM 1872. HEALTH EFFECTSThe th
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CHROMIUM 1892. HEALTH EFFECTSand st
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CHROMIUM 1912. HEALTH EFFECTSwater
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CHROMIUM 1932. HEALTH EFFECTSlympho
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Table 2-5. Genotoxicity of Chromium
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Species (test system)Subcellular ta
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Species (test system)Prokaryotic or
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Species (test system)Mammalian cell
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Species (test system)Subcellular ta
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Species (test system)Eukaryotic org
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CHROMIUM 2072. HEALTH EFFECTSwas fo
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CHROMIUM 2092. HEALTH EFFECTSIn con
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CHROMIUM 2112. HEALTH EFFECTSor env
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CHROMIUM 2132. HEALTH EFFECTSChildr
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CHROMIUM 2152. HEALTH EFFECTSabnorm
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CHROMIUM 2172. HEALTH EFFECTScells)
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CHROMIUM 2192. HEALTH EFFECTSHuman
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CHROMIUM 2212. HEALTH EFFECTSFigure
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CHROMIUM 2232. HEALTH EFFECTShad no
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CHROMIUM 2252. HEALTH EFFECTS5 fema
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CHROMIUM 2272. HEALTH EFFECTS0.1 µ
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CHROMIUM 2292. HEALTH EFFECTSRecent
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CHROMIUM 2312. HEALTH EFFECTS2.11 M
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CHROMIUM 2332. HEALTH EFFECTSpotass
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CHROMIUM 2352. HEALTH EFFECTSN,N,N'
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CHROMIUM 2372. HEALTH EFFECTSDiffer
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CHROMIUM 2392. HEALTH EFFECTS
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CHROMIUM 2412. HEALTH EFFECTSA majo
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CHROMIUM 2432. HEALTH EFFECTSlethal
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CHROMIUM 2452. HEALTH EFFECTSanimal
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CHROMIUM 2472. HEALTH EFFECTSchroma
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CHROMIUM 2492. HEALTH EFFECTSresult
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CHROMIUM 2512. HEALTH EFFECTSeffect
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CHROMIUM 2532. HEALTH EFFECTSgenoto
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CHROMIUM 2552. HEALTH EFFECTSadditi
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CHROMIUM 2572. HEALTH EFFECTS2.12.3
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CHROMIUM 2593. CHEMICAL AND PHYSICA
Page 281 and 282:
CharacteristicSynonym(s)Table 3-1.
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CharacteristicTable 3-1. Chemical I
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CharacteristicTable 3-1. Chemical I
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CHROMIUM 2734. PRODUCTION, IMPORT/E
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Derived from HazDat 2000Figure 5-1.
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CHROMIUM 2845. POTENTIAL FOR HUMAN
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State bTable 5-2. Releases to the E
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Sample matrixTable 6-1. Analytical
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CHROMIUM 3186. ANALYTICAL METHODSth
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Sample matrixAir (totalchromium)Air
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Sample matrixAtomosphericdeposition
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Sample matrixSoil, sedimentand slud
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CHROMIUM 3266. ANALYTICAL METHODSpr
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CHROMIUM 3287. REGULATIONS AND ADVI
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CHROMIUM 3408. REFERENCES*Albert RE
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CHROMIUM 3428. REFERENCES*ATSDR. 19
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CHROMIUM 3448. REFERENCESBerg NO, B
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CHROMIUM 3468. REFERENCES*Bragt PC,
Page 368 and 369:
CHROMIUM 3488. REFERENCESCarter WW.
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CHROMIUM 3508. REFERENCESCohen MD,
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CHROMIUM 3528. REFERENCES*De Flora
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CHROMIUM 3548. REFERENCES*Elbetieha
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CHROMIUM 3568. REFERENCES*EPA. 1987
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CHROMIUM 3588. REFERENCES*Fagliano
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CHROMIUM 3608. REFERENCESFregert S,
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CHROMIUM 3628. REFERENCES*Glaser U,
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CHROMIUM 3648. REFERENCES*Hallmark
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CHROMIUM 3668. REFERENCESHneihen AS
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CHROMIUM 3688. REFERENCESIkarashi Y
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CHROMIUM 3708. REFERENCESKamath SM,
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CHROMIUM 3728. REFERENCES*Kirkpatri
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CHROMIUM 3748. REFERENCES*Krishnan
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CHROMIUM 3768. REFERENCESLarsen EH,
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CHROMIUM 3788. REFERENCES*Liden S,
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CHROMIUM 3808. REFERENCESLucia-Jand
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CHROMIUM 3828. REFERENCESMathur AK,
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CHROMIUM 3848. REFERENCESMiksche LW
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CHROMIUM 3868. REFERENCESMyers MJ,
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CHROMIUM 3888. REFERENCES*NIOSH. 19
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CHROMIUM 3908. REFERENCES*Offenbach
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CHROMIUM 3928. REFERENCES*Paustenba
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CHROMIUM 3948. REFERENCESRafnsson V
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CHROMIUM 3968. REFERENCESRyberg D,
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CHROMIUM 3988. REFERENCES*Schuhmach
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CHROMIUM 4008. REFERENCES*Simpson J
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CHROMIUM 4028. REFERENCESSteenland
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CHROMIUM 4048. REFERENCESSunderman
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CHROMIUM 4068. REFERENCES*Triebig G
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CHROMIUM 4088. REFERENCES*Venier P,
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CHROMIUM 4108. REFERENCES*Wedeen RP
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CHROMIUM 4128. REFERENCESWong PK. 1
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CHROMIUM 4159. GLOSSARYAbsorption
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CHROMIUM 4179. GLOSSARYImmediately
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CHROMIUM 4199. GLOSSARYand physiolo
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CHROMIUM 4219. GLOSSARYToxicokineti
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CHROMIUM A-2APPENDIX AMRLs are inte
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CHROMIUM A-4APPENDIX AUncertainty f
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CHROMIUM A-6APPENDIX Aincreased in
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CHROMIUM B-1APPENDIX BUSER'S GUIDEC
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CHROMIUM B-3APPENDIX Beffects. The
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13141516(ppm)1000010001001010.10.01
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CHROMIUM B-7APPENDIX BTo derive an
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CHROMIUM C-2APPENDIX CLC LoLC 50LD
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