TOXICOLOGICAL PROFILE FOR CHROMIUM - Davidborowski.com

66 Mouse Gd12- 74 (reduced ovary and Al-Hamood et al.(BALB/c) Ld20testis weights in 1998(W)offspring and impairedfertility in femaleCrCI 3(Ill)off spring)67 Mouse(BALB/c)Gd12-Ld20(W)68 Mouse 20 d(Swiss albino) (W)69 Mouse Gd 1-19(albino) 19 d(W)TABLE 2-2. Levels of Significant Exposure to Chromium - Oral (continued)Exposure/LOAELDuration/Key to a Species Frequency NOAEL Less Serious Serious Reference/figure (Strain) (Specific Route) System (mg Cr/kg/day) (mg Cr/kg/day) (mg Cr/kg/day)Form66 F (delayed time of vaginalopening and impairedfertility in female offspring)Al-Harnood et al.1998K 2Cr 2O (VI) 752 F (reduced caudal ossification Junaid et al.in fetuses: decreased fetal 1996aweight; post-implantation K 2Cr 2O (VI) 7loss)46 (increased resorptions, Trivedi et al. 1989reduced ossification, gross Kanomalies)2Cr 2O (VI) 72. HEALTH EFFECTSCHROMIUM 85