17/18 January 2007 Wiener Neustadt - Czelo

National R&D Institute for Microtechnology
Address Erou Iancu Nicolae 32B Romania
77190 - Bucharest
Phone / Fax +40-21-490.82.12 / +40-21-490.82.38
www http://www.imt.ro
Size 51-250
Organisation Type RTD Institute
Contact Person
Name specialist roxana vasilco
Position head of group
Email roxanav@imt.ro
Type of co-operation (Offered, Requested) Areas of activity
Licence agreement
Technical Co-operation (R&D) Boths
Joint research project Boths
Joint-venture agreement
Manufacturing agreement
Commercial agreement
Financial agreement
• Electronics, Microelectronics
• Biosensor
• Medicine, Human Health
• Electromedical/Medical Equip.
• Biology / Biotechnology
•
Short description of company
Mission: research and development in micro- and nanotechnologies, technology transfer, education and training,
dissemination, development of the national strategy in the field.
Strategic role: a “technological pole” for multidisciplinary activities, integrating research, education and technology
transfer, playing a national role through networking and partnership (with University “Politehnica” of Bucharest),
emerging as a regional centre
1. Profile: RTD: microfluidic systems based on logic gates for biomedical applications
DESCRIPTION: The main scientific objective of this project is to realize a “lab-on-a-chip” or µTAS microfluidic
system with the help of which rheological properties of the non-Newtonian fluids will be studied. The microfluidic
system will have multiple components, each of them being designed for a certain function: (a) a network of
straight microchannels needed to determine the flow velocity of the biological fluid and the non-Newtonian
biological fluid viscosity for different pathology; (b) a network of endothelial shaped microchannels needed to
determine the motility and deformability of the cells found inside the fluid; (c) a network of bifurcated
microchannels needed to model blood flow through the junction between large and small blood vessels; (d) a
network of stenosed microchannels needed to model blood flow through an obstructed blood vessel, such as in
the case of arthrosclerosis or the case of calcium or fat deposits on the interior wall of the blood vessel; (e)
microheaters needed to create gradients of temperature for selecting the biological particles in function of their
size; (f) input and output reservoirs, needed to store the fluid until it is pushed through or extracted from the
microchannel system. We will also study the influence of the roughness of the interior vessel walls on the fluids
flow, by applying a surface contour on the channel walls similar to the lining of the endothelial blood vessels, or
by porosifying the microchannel walls.
The microgear wheels system will be created to pump fluid and to measure the viscosity of the fluid. The gear
wheels was fabricated using the silicon surface micromachining technology, combining the undercut and refill
technique with pin-joint bearing permitting the fabrication of bushings.
A giant magnetoresistive sensor with a non-contacting transduction mechanism, in full Wheatstone bridge
configurations with four active resistors in the middle of the sensitive structure and four shielded reference
resistors, very attractive for detection of low magnetic fields in lab-on-a-chip applications, is used to transform the
rotor rotation rate into an electrical signal.
2. Profile: RTD: microfluidic systems based on logic gates for biomedical applications
3. Profile: RTD: microfluidic systems based on logic gates for biomedical applications