RDoC - Borderline Personality Disorder

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NIMH Strategic Plan: Goal 1.4• “Develop, for research purposes, new ways ofclassifying mental disorders based on dimensions ofobservable behavior and neurobiological measures.”• Identify fundamental components that may span multipledisorders (e.g., executive function, affect regulation)• Develop reliable and valid measures of these fundamentalcomponents for use in basic and clinical studies• Determine the full range of variation, from normal to abnormal• Integrate genetic, neurobiological, behavioral, environmental,and experiential components10/24/2011 2
“If I only had a brain”:Toward new models of mental disorders• Shift from traditional clinicalphenomenological views(cognition/emotion, mind/brain) to aview of behavior grounded infundamental behavioraldimensions, as implemented bymajor brain circuits• I.e., treat our data as constructs• Measures in different responsesystems: behavior, self-reports(phenomenology), physiology10/24/20113
Page 1: NIMH Research Domain Criteria Proje
Page 5 and 6: The public intellectuals catch up
Page 7: Borderline as temperament variants,
Page 10 and 11: RDoC: MatrixConstruct: A concept su
Page 12 and 13: RDoC: MatrixAntagonismNegative Affe
Page 14 and 15: RDoC: MatrixNegative AffectivityAnt
Page 16 and 17: Classic motivation centers
Page 18 and 19: RDoC and Clinical Use• Not intend

RDoC - Borderline Personality Disorder

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