Pathology of Head and Neck Malignancies - Aroi.org

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Spindle cell squamous carcinoma• Fungating, ulcerating,polypoidal / exophytic• Malignant undifferentiatedspindle cell proliferation inpresence of differentiatedsquamous cell component• CK –negative in upto 40%of cases• Prognosis: worse
Basaloid Squamous cell carcinoma• Pyriform sinus, supraglottic,oral cavity, tongue, tonsil,palate• Alcohol, tobacco use• Solid, lobular, cribriform, nest,cords, trabeculae• Aggressive, high grade,multifocal, deeply invasive &metastatic even at initialpresentationEarly mets to LN & visceralorgans• Treat: Radical excision, neckdissection, RT & CT
Page 3 and 4: Tumors of the upper respiratory tra
Page 5 and 6: Malignant epithelial and neuroectod
Page 7 and 8: Squamous cell carcinoma ofsinonasal
Page 9 and 10: • Secondary malignancyeither at a
Page 11: Verrucous carcinoma• WD locally d
Page 15 and 16: Nasopharyngeal Carcinoma• Age ran
Page 17 and 18: • Non-keratinizing- differentiate
Page 19 and 20: Olfactory neuroblastoma• Upper1/3
Page 21 and 22: CGNFSynS100
Page 23 and 24: Treat: complete surgical eradicatio
Page 25 and 26: Mucosal malignant melanoma• 0.5-3
Page 27 and 28: EM: melanosome &premelanosome• Ag
Page 29 and 30: • Intestinal/colonic types:papill
Page 31 and 32: Non-epithelial malignant neoplasm
Page 33 and 34: Extramedullary plasmacytoma• 3-5%
Page 36 and 37: • With surgical excision 5-yr sur
Page 38 and 39: Osteosarcoma• 10% of OS occur in
Page 40 and 41: Chondrosarcoma• 5-12%• 4 th -7
Page 42 and 43: Tumors of oral cavity• Squamous c
Page 44 and 45: ME carcinoma• Most common maligtu
Page 46 and 47: Adenoid cystic carcinoma• 4 Th -6
Page 48 and 49: Thyroid and parathyroid malignancie
Page 50 and 51: Follicular carcinoma• Uncommon•
Page 52 and 53: Anaplastic carcinoma of thyroid•
Page 54 and 55: Orbital malignancies• Basal cell

Pathology of Head and Neck Malignancies - Aroi.org

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