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Visual Psychophysics / Physiological Optics - ARVO

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<strong>ARVO</strong> 2013 Annual Meeting Abstracts by Scientific Section/Group – <strong>Visual</strong> <strong>Psychophysics</strong> / <strong>Physiological</strong> <strong>Optics</strong>its change caused by accommodation was calculated based on theacquired image.Results: Repeated measurements were taken in each accommodativestate. Compared with relaxed state (0D), the mean thickness variationaround the central fovea was 7.4957±8.3616 μm at 5Daccommodation. In further study, we will collect more data toanalyze the variations of axial length and retinal thickness.Conclusions: Preliminary result showed that the thickness betweenILM and RPE in macular has a slight change during accommodation.Commercial Relationships: Chuanqing Zhou, None; ShanhuiFan, None; Zhe Chen, None; Xinyu Chai, NoneSupport: the National Basic Research Program of China(2011CB707504), National Natural Science Foundation of China(81171377)Program Number: 4264 Poster Board Number: B0301Presentation Time: 8:30 AM - 10:15 AMThe Effect Of Age On The Lens Ultrastructure DuringAccommodation As Measured Using Slit Lamp Photos AndWave Front AnalysisRebecca K. Zoltoski 1 , Elizabeth Wyles 1 , Jennifer S. Harthan 1 , Jer R.Kuszak 2 . 1 Illinois College of Optometry, Chicago, IL; 2 LensAR,Orlando, FL.Purpose: During dynamic focusing, the shape, as well as the ultrastructureof the lens is changed. We have hypothesized that uniquestructural features and organization of fiber cells enables them tointerface at the sutures resulting in a change in surface curvature ofthe lens, as well as an increase in thickness, allowing near focus tooccur. We are reporting extended data on lens slit lamp photos, OCTof lens thickness changes, and sequential ray tracing analysis of thepatterns associated with the lens sutures to provide additional insightinto the importance of the ultra-structure of the lens in theaccommodative process.Methods: OCT (Visante), wavefront analysis (iTrace), and slitlamp photos (Haag Streit, 16X magnification, dilated eye) werecollected on the right eye of normal subjects, between the ages of 7 -63 (n=30). Accommodation was stimulated using minus lenses infront of the viewing eye in 2.5 D increments until the subject couldno longer clearly view the target. For the photos a prism system wasused to keep the eye appropriately oriented. The objectiveaccommodative response was calculated as the change from adistance measurement refractive value. ImageJ (NIH) was used toanalyze the area of the sutural components. Data were analyzed usingSystat v11 to correlate accommodative response (AR) with totalHOA, SA and the foil patterns, as well as changes in slit lamp sutureareas. Spearman Rank Correlation coefficients and p values arepresented.Results: Lens thickness increases by 0.13 ± 0.05 μm/D duringaccommodation. The total foil aberration pattern was correlated withAR (r2=0.5, p=0.04). There was a decrease in suture band thicknessthat correlated with the AR (r2=-0.5, p

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