Visual Psychophysics / Physiological Optics - ARVO

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ARVO 2013 Annual Meeting Abstracts by Scientific Section/Group – Visual Psychophysics / Physiological OpticsCommercial Relationships: Patricia A. Piers, Abbott MedicalOptics (E); Sanjeev Kasthurirangan, Abbott Medical Optics (E);Basilios Sideris, AMO Groningen BV (R)Support: SNN Eoropean fund for Regional Development and theMinistry of Economic Affairs, Peaks in the Delta grants 086 and 087Program Number: 844 Poster Board Number: B0068Presentation Time: 1:00 PM - 2:45 PMPredicted changes in the cut surface and weight of colored acrylicintraocular lenses in 20 yearsKenji Kawai. Ophthalmology, Tokai Univ School of Medicine,Isehara, Japan.Purpose: We previously reported that long-term immersion ofintraocular lenses (IOLs) in water at high temperature leads to theiropacification and deterioration, depending on differences inmaterials. This study aimed to examine predicted changes in the cutsurface and weight of colored acrylic IOLs (colored IOLs) in 20years.Methods: Colored IOLs manufactured by various companies wereimmersed in 50-mL screw-tube bottles containing ultrapure water at100 degrees for 115 days (equivalent to 20 years). Externalappearance and cut surfaces were observed before and after drying ofthe IOLs, and then percent changes in weight before and aftertreatment were determined.IOLs used: We used 3 colored IOLs of each of the following 5 typesmanufactured by different companies - SN60WF (Alcon) and AN6K(KOWA) by the cast-molding method and NY-60 (HOYA), NX-60(Santen), and NS-60YG (NIDEK) by the lathe-cut method.Results: External appearance: Opacification was observed to avarying degree in all IOLs except AN6K and NX-60. After drying ata room temperature of 25 degrees for 48 hours, opacificationdisappeared in all IOLs except SN60WF.Cut surfaces: Opacification was observed to a varying degree for allIOLs. After drying, opacification was observed in all except NS-60YG.Percent changes in weight: Percent changes in weight before dryingwere unmeasurable for SN60WF, -3% for AN6K, -0.9% for NY-60,+2.3% for NX-60, and +0.6% for NS-60YG. The changes afterdrying were -1.5% for SN60WF, -9.8% for AN6K, -2.7% for NY-60,-3.7% for NX-60, and -1.5% for NS-60YG.Conclusions: There were differences in opacification among cutsurfaces of IOLs. Percent changes in weight before and after dryingdiffered by approximately 6% for AN6K and NX-60. Thesedifferences may be attributable to different methods of manufacturingacrylic resin.Commercial Relationships: Kenji Kawai, Alcon (F), KOWA (F),HOYA (F), Santen (F), NIDEK (F)The implanted ICL size and vault at 6 months follow-up werecompared with a calculated ICL size and expected vault using aregression formula reported by the same author previously.Pneumatic tonometer, specular microscopy, and ultrasoundbiomicroscopy (UBM) were performed before and after surgery toevaluate the safety by measuring intraocular pressure (IOP),endothelial cell count (ECC), ICL vault, angle opening distance at500 μm from the scleral spur (AOD 500) and trabecular-iris angle(TIA).Results: The mean follow-up period of 16 eyes of 9 patients was28.00 ± 15.03 months and preoperative ACD was 2.70 ± 0.08 mm.Preoperative and postoperative spherical equivalent (SE) were -10.27± 2.38 and -0.11 ± 0.51 diopters, respectively. Postoperativeuncorrected and best corrected visual acuity were 0.89 ± 0.24 and0.98 ± 0.19, respectively.The implanted ICL size revealed no significant difference withcalculated ICL size (independent t-test, p=.356). However,postoperative vault was 0.346 ± 0.179 mm, which was lower thanexpected vault of 0.531 ± 0.173 mm calculated by a regressionformula (independent t-test, p=.000).The pre- and postoperative mean AOD 500 were 0.379 ± 0.088 and0.267 ± 0.111 mm, and mean TIA were 33.68 ± 5.37 and 23.67 ±8.33 degrees, respectively. There were significant differencesbetween preoperative and postoperative AOD500 and TIA(independent t-test, p=.000). However, there was no severecomplication such as elevated IOP, ECC reduction, cataractformation or angle closure glaucoma.Conclusions: ICL implantation performed in the eyes with shallowACD showed good visual outcomes without severe complicationduring relatively long follow-up period. The size of ICL which wascalculated to get ideal vault of 500 to 750 μm, but it resulted in lowervault than expected. It suggests the necessity for modulation of ICLsizing method in patients with low anterior chamber depth.Program Number: 845 Poster Board Number: B0069Presentation Time: 1:00 PM - 2:45 PMSafety and clinical results of posterior chamber phakicintraocular lens implantation in low anterior chamber depthMin gyu Lee, Dong Hui Lim, Eui Sang Chung, Tae-Young Chung.Ophthalmology, Samsung medical center, Seoul, Republic of Korea.Purpose: To investigate the safety and present clinical experiences ofthe Visian implantable Collamer lens (ICL) implantation in patientswith shallow anterior chamber.Methods: This retrospective study included patients with anteriorchamber depth (ACD) lower than 2.8 mm who underwent ICLimplantation. Implanted ICL size, pre- and postoperative visualacuity, refractive errors, postoperative central vault, intra- andpostoperative complications were recorded through a medical chartreview.Commercial Relationships: Min gyu Lee, None; Dong Hui Lim,None; Eui Sang Chung, None; Tae-Young Chung, NoneProgram Number: 846 Poster Board Number: B0070Presentation Time: 1:00 PM - 2:45 PMComparative study of visual performance of two multifocalintraocular lens : two-year follow-upBalmitgère Thomas 1, 2 , Burillon Carole 2, 1 . 1 Ophthalmology, HôpitalLyon Sud, Pierre-Bénite, France; 2 Ophthalmology, Hôpital EdouardHerriot, Lyon, France.Purpose: To compare visual performance and functional tolerance oftwo multifocal diffractive intraocular lens, AcrySof ReSTOR©2013, Copyright by the Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Go to iovs.org to access the version of record. For permissionto reproduce any abstract, contact the ARVO Office at arvo@arvo.org.
ARVO 2013 Annual Meeting Abstracts by Scientific Section/Group – Visual Psychophysics / Physiological OpticsSN60D3 (Alcon, Inc.) and Acri.LISA 376D (Carl Zeiss Meditec),two years after cataract surgery.Methods: This monocentric, prospective, comparative study wasconducted between March 2009 and September 2011. Inclusioncriteria were patients between 50 and 80 years, no longer willing towear glasses or contact lenses for distance and near vision, andwanting a cataract surgery with bilateral implantation. Cataractsurgery was performed by the same surgeon using the samephacoemulsification technique . The parameters analyzed werebiomicroscopic examination; monocular and binocular visual acuitywith and without spectacle correction using ETDRS charts, at adistance of 4 meters for far vision, 66 centimeters for intermediatevision, 33 centimeters for near vision; monocular contrast sensitivityin photopic conditions ; glare sensitivity ; a quality of lifequestionnaire, assessing visual disturbances and dependence onglasses ; a macular OCT (Optical Coherence Tomography) analysisto exclude a maculopathy.Results: 20 eyes (10 patients) received the ReSTOR intraocular lens(IOL) and 24 eyes (12 patients) received the Acri.LISA IOL in theEdouard Herriot Hospital, Lyon. There was no statistically significantdifference (α=5%) between the two lens in terms of visual acuity forfar and near vision, for monocular and binocular vision, for contrastsensitivity and glare test . There was a statistically significantdifference in favor of Acri.LISA group for intermediate visual acuityspecially for monocular uncorrected visual acuity (p = 0.03),binocular uncorrected visual acuity(p = 0.041) and binocularcorrected visual acuity (p = 0.004) . The analysis of quality of lifequestionnaire did not find any statistically significant differencebetween the two groups and any correlation between visualdiscomfort during night driving and glare test.Conclusions: This study shows that both IOL have similar visualperformance (good level of satisfaction without eye glasses).Intermediate vision is better in the Acri. LISA group. It could beexplained by the asphericity of the lens increasing the depth of field.This study (2 years of follow-up) confirms the results of previousstudies reported in the literature (6 months and 1 year follow-up).Commercial Relationships: Balmitgère Thomas, None; BurillonCarole, NoneProgram Number: 847 Poster Board Number: B0071Presentation Time: 1:00 PM - 2:45 PMProposed novel schematic eye model for testing intraocular lensperformanceCristina Mendoza 1, 3 , Anabel S. Sanchez-Sanchez 2 , Omar Teran-Jimenez 2 , David Rivera 4 , Claudia Palacio 1 , Laura Leticia Arroyo-Muñoz 1 , Oscar Guerrero-Berger 1 , Ernesto Suaste Gomez 2 .1 Fundacion Hospital Nuestra Senora de la Luz, Mexico, Mexico;2 Centro de Investigación y de Estudios Avanzados del InstitutoPolitécnico Nacional, Mexico, Mexico; 3 Hospital General ManuelGea González, Mexico, Mexico; 4 IDISA Instituto para el DesarrolloIntegral de la Salud, Mexico City, Mexico.Purpose: How does a patient actually sees once he has been placedan intraocular lens (IOL) is a subjective evaluation sometimesdifficult to understand by the clinicians. An objective way to knowhow an IOL is performing would be to create a schematic eye thatcould show us with real images how the patient is perceiving thoseimages. Here we present a proposed novel schematic eye wheredifferent IOLs can be placed, and images of different targets can betaken in order to objectively analyze them.Methods: A schematic eye consisting of a optical microscope with acamera, a platform holding the IOL, a diaphragm that simulates thepupil with a range of aperture of 2-5mm, a pattern target (simulatingan optotype) and a light source (See figure 1) were arranged so theimages taken by the camera could be in focus with the target. In thisschematic eye, the target can be lowered, elevated or in a fixedposition, in the latter the images stay in focus while opening andclosing the diaphragm simulating a pupil, like that, the differencesfrom the same image taken with different diaphragm diameters canbe analyzed. Also at the lens position any kind of IOL can be placed.For this study parallel or concentric line targets were used, and arefractive - diffractive - apodized IOL was placed in the schematiceye and images were recorded.Results: ubjectively with 2 and 3 mm diaphragm diameters, theimages were clear in the central and peripheral areas of the image.When the diaphragm was opened wider, the central image lost qualityand the peripheral image increased its sharpness. When elevating orlowering the target a similar effect was found, with the peripheral andcentral image changing in sharpness.Conclusions: This novel schematic eye is an alternative to study theimages produced by different IOLs at variable diaphragm diameters.Images can be analyzed qualitatively and in the future with theappropriate software quantitatively. This schematic eye will helpclinicians and researchers to make better analysis of the behavior andperformance of optics systems related to cataract surgery, intraocularlenses either focal or multifocal and it variations with pupil size.Figure 1. Schematic eye and its components.Figure 2. Same image taken with different diaphragm diameters.Commercial Relationships: Cristina Mendoza, None; Anabel S.Sanchez-Sanchez, None; Omar Teran-Jimenez, None; DavidRivera, None; Claudia Palacio, None; Laura Leticia Arroyo-Muñoz, None; Oscar Guerrero-Berger, None; Ernesto SuasteGomez, NoneProgram Number: 848 Poster Board Number: B0072Presentation Time: 1:00 PM - 2:45 PM©2013, Copyright by the Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Go to iovs.org to access the version of record. For permissionto reproduce any abstract, contact the ARVO Office at arvo@arvo.org.
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