Visual Psychophysics / Physiological Optics - ARVO

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ARVO 2013 Annual Meeting Abstracts by Scientific Section/Group – Visual Psychophysics / Physiological OpticsSA6 between each eye (ie SA4-0.4μm and SA6+0.2μm on one eyeand SA4+0.4μm and SA6-0.2μm on the other eye). Pupil diametervariations had to be taken into account when using simulated images.The decrease of pupil size in near vision led to a better TF subjectivevision especially with combination of SA4 and SA6. Although wedistinguished two different optical performance profiles (ie (i) gooddistance vision/acceptable intermediate vision/poor near vision, and(ii) good distance vision/poor intermediate vision/good near vision)there was a good correlation (r2=0.89) between AUC and meanquality of vision at distance/intermediate and near vision.Conclusions: There is no binocular summation of quality of vision.However the use of different SA profiles on each eye especiallyreverse profile of SA4 and SA6 profile involved a better binocular TFsubjective vision.Commercial Relationships: Guillaume Van Der Meer, None;Pierre-Jean Pisella, None; Richard Legras, NoneProgram Number: 828 Poster Board Number: B0052Presentation Time: 1:00 PM - 2:45 PMInfluence of Pupil Diameter on Intraocular ScatteringMeasurements Based on Double Pass Images in Patients withDifferent Types of CataractsJaume Pujol 1 , Juan Carlos Ondategui Parra 2 , Joan A. Martinez-Roda 2 , Meritxell Vilaseca 1 , Mouafk Asaad Ammaar 3 . 1 Centre forSensors, Instruments and Systems Development (CD6),, UniversitatPolitecnica Catalunya, Terrassa, Spain; 2 University Vision Center(CUV), Universitat Politècnica Catalunya (UPC), Terrassa, Spain;3 Ophthalmology, Hospital de Terrassa, Terrassa, Spain.Purpose: To assess the influence of pupil diameter size onintraocular scattering measurements obtained from double passimages in patients with different type of cataracts.Methods: Intraocular scattering was measured using a comercialdouble-pass system (Optical Quality Analysis System, OQAS,Visiometrics, Spain) (Güell et al. J Cataract Refr Surg 2004) andquantified using Objective Scattering Index (OSI)(Artal et al. Plosone 2011; Vilaseca et al Br. J. Ophthalmol. 2012) in four groups ofpatients with cataracts (nuclear (NC), cortical (CC), posteriorsubcapsular (PSC) and cortical-nuclear mixed (CNMC)). Cataractswere classified using a LOCS III system. Measurements wereperformed using two different pupil diameters: 4mm (with andwithout cycloplegic drops) and 7mm (with cycloplegic drops), whichwere obtained using the artificial pupil of OQAS system.Results: 56,5% of the subjects were female where 48 eyes (of 55patients with cataracts). Cataract classification showed: 29 NC, 12PSC; 18 SPC and 26 CNMC). Mean ages (± SD [range]) were of68.3±8.20 (47 to 85 yr.) There are not differences in OSI valuesobtained for a pupil diameter of 4 mm either with or withoutcyclopegia. The correlations between OSI (4mm) and OSI (7mm)using cyclopegia were: NC r=0.804 (p=0.00); PSC r=0.608 (p=0.07);CC r=0.957 (p=0.00) and CNMC r=0.769 (p=0.00). OSI parametershowed a high correlation between both pupil diameters. Mean± SDOSI results for 4mm and 7mm pupil were: NC 3.7±2.2 / 6.0±3.4;PSC 3.1±1.7 / 4.8±2.0; CC 3.5±2.3 / 6.3±3.8 and CNMC 5.0±3.4 /7.4±3.5. All OSI values presented a proportional increase for eachtype of cataracts. Similar changes were obtained considering theclassification according LOCSIII system. The increase in OSI values(lower in PSC and higher in CC) probably can be due to theperipherical distribution of cataract in CC and to the central lensopacity on PSC.Conclusions: OSI results increase when pupil diameter is higher, butwe have not found difference to classify different types of cataracts.We can conclude that OSI parameter provides useful information toclassify cataracts regardless of pupil diameter. Future work will befocused on a larger number of patients with cortical and subcapsularcataracts.Commercial Relationships: Jaume Pujol, Visiometrics (P); JuanCarlos Ondategui Parra, None; Joan A. Martinez-Roda, None;Meritxell Vilaseca, None; Mouafk Asaad Ammaar, NoneSupport: “Ministerio de Educación y Ciencia”, Spain (grant n0DPI2011-30090-C02-01 and European UnionProgram Number: 829 Poster Board Number: B0053Presentation Time: 1:00 PM - 2:45 PMCapsular Adhesion to Intraocular Lens Evaluated In Vivo UsingUltralong-scan-depth Optical Coherence TomographyYinying Zhao, Jin Li, Weilin Lu, Xiaoying Xing, Fan Lu, Yune Zhao.wenzhou medical college, Wenzhou, China.Purpose: A firm capsular apposition to the intraocular lens (IOL)could inhibit lens epithelial cell proliferation and migration. Manyresearchers have focused on the design and material of the IOL.However, we found few studies evaluating the capsule-IOLinteraction in highly myopic eyes. This study was to evaluate the invivo capsular apposition to IOL in patients by ultralong-scan-depthoptical coherence tomography (OCT).Methods: It is an observational case series research. Thirty eyes from30 cataract patients were recruited at the Affiliated Eye Hospital,Wenzhou Medical College, of which 15 eyes were highly myopic(axial length >26 mm) and 15 eyes were emmetropic (22 mm
ARVO 2013 Annual Meeting Abstracts by Scientific Section/Group – Visual Psychophysics / Physiological OpticsMakoto Inoue 1 , Jiro Hidaka 2 , Akito Hirakata 1 . 1 Ophthalmology,Kyorin Eye Center, Mitaka, Japan; 2 HOYA Corp., Tokyo, Japan.Purpose: To evaluate the effect of temperature in restoration ofacrylic intraocular lenses (IOLs) after injection through a cartridge.Methods: Acrylic IOLs (SA60AT; Alcon, 251; HOYA, YA-65BB;HOYA, W-60, Santen, NX-70; Santen) were loaded or preloaded in acartridge with viscoelastic material and injected into a water chamberunder temperature control at 24 or 34 C°. Wavefront analyzer(LAMBDA-X, NIMO TR0815) was used to measure the form ofIOLs. Time to restore the form of the IOLs was defined as Δcylinderpower (difference from the baseline) < 0.2 diopter.Results: All IOLs restored within 2 minutes at 34 C°. At 24 C°,SA60AT and 251 restored within 3 minutes but YA-65BB and W-60(single-piece) required 3.5 minutes and NX-70 (three piece IOL withsame material of W-60) up to 6 minutes. The central optical thicknessof NX-70 (7.0 mm diameter) was 0.865 mm and was thicker than thatof W-60 (6.0 mm diameter) at 0.640 mm. The cross section of thecartridge for NX-70 was round shape with mean diameter of 2.17 mmand that for W-60 was oval shape with 1.65 mm of mean diameter.Conclusions: Restoration of IOL was dependent on temperature.However it may depend on the thickness of IOL and inner shape ofthe cartridge.with respect to PI to the solutions of a damped harmonic oscillator.Four parameters are used to characterize the wobbling effect, i) theamplitude (i.e., the overshooting effect with respect to the stableposition of PIV), ii) the oscillation frequency, iii) the damping ratioand iv) the stationary time (the time constant of the wobbling effect).Videos were recorded in eight subjects during a series of 15 saccadicmovements performed horizontally (center-temporal) and vertically(center-up).Results: The mean value of the oscillation frequency after a saccadicwas 19 Hz (standard deviation 6 Hz) and the mean damping ratio was0.45 (SD 0.10). The average stationary time was 57 msec (SD 20msec). Given that the mean post-saccadic suppression time is around50 msec (Diamond et al, Journal of Neuroscience, 2000) the visualeffect of the lens wobbling in normal subjects will not be noticeable.Comparing vertical and horizontal movement, we only observeddifferences in the amplitude, larger in the case of the horizontalmovement (252 microns) than in the vertical upwards movement(194 microns), which perhaps reveals some gravity effects or anasymmetric distribution of tension on the lens zonule.Conclusions: A new instrument to measure crystalline lens stabilityhas been developed and successfully tested in normal subjects. It maybe useful for a wide range of future studies involving lens stability.Commercial Relationships: Juan Tabernero, None; AntonioFernández, None; Pablo Artal, AMO (C), Voptica SL (P), VopticaSL (I), AMO (F), Calhoun Vision (F), Calhoun Vision (C), AcuFocus(C)Support: Ministerio de Ciencia e Innovación, Spain (grantsFIS2010-14926 and CSD2007-00013) and Fundación Séneca(Region de Murcia, Spain), grant 4524/GERM/06Commercial Relationships: Makoto Inoue, None; Jiro Hidaka,HOYA Corporation Medical Division (E); Akito Hirakata, NoneProgram Number: 831 Poster Board Number: B0055Presentation Time: 1:00 PM - 2:45 PMStability of the human crystalline lens measured with a hightemporal resolution dynamic Purkinje-meter systemJuan Tabernero, Antonio Fernández, Pablo Artal. Laboratorio deOptica, Universidad de Murcia, Murcia, Spain.Purpose: To measure the dynamic stability of the human crystallinelens by using a custom-made new instrument that tracks the lensoscillations following a controlled saccadic eye movement (lenswobbling effect)Methods: We developed a modified prototype of a Purkinje-meterthat uses a high temporal resolution CMOS camera attached to atelecentric lens and a semicircular ring of IR LEDs placed on the lensaperture‘s rim. Saccadic eye movements of 9‘ amplitude wereinduced by two flickering visible LEDs (1 Hz) placed in a central anda peripheral position with respect to the objective-camera axis. Fourflickering orientations were possible (nasal, temporal, inferior andsuperior). The wobbling effect is a quick oscillation of Purkinjeimage PIV (posterior lens surface reflection) with respect to PI(corneal reflection) that follows immediately after a change in thedirection of gaze and is captured at high speed (400 frames perProgram Number: 832 Poster Board Number: B0056Presentation Time: 1:00 PM - 2:45 PMRotational stability of two single-piece toric acrylic intraocularlensesGernot Steinwender, Navid Ardjomand. Dept of Ophthalmology,Medical University Graz, Graz, Austria.Purpose: To assess the rotational stability of two single-piece toricacrylic intraocular lenses (IOL) during the first postoperative month.Methods: This retrospective case series included 15 eyes (14patients) with age-related cataract and corneal astigmatism ≥1.50diopters [D]. Corneal astigmatism was measured using the PentacamScheimpflug system (Oculus) and IOL biometry was performed withlaser interferometry (IOL Master). All eyes were analyzed afteruncomplicated phacoemulsification with in-the-bag implantation oftoric IOL (Hoya iSert 351; Rayner T-flex). Rotational stability of theIOL was assessed by comparison of images taken by the microscopevideo camera intraoperatively with retroillumination photographs at 1month postoperatively.Results: The overall mean absolute IOL rotation was 7.67 degrees ±5.54 (SD). The mean absolute IOL rotation was 5.60 degrees ± 3.21(SD) for Rayner T-flex IOL and 6.11 degrees ± 4.53 (SD) for HoyaiSert 351 respectively.Conclusions: Both investigated acrylic toric IOL seem to berotationally stable with just mild IOL rotation in the firstpostoperative month and can be recommended for the correction ofastigmatism during cataract surgery.Commercial Relationships: Gernot Steinwender, None; NavidArdjomand, NoneProgram Number: 833 Poster Board Number: B0057Presentation Time: 1:00 PM - 2:45 PMMulticenter clinical evaluation of an aspheric diffractivemultifocal one-piece IOLsecond).Stability is assessed by fitting the relative movement of PIV©2013, Copyright by the Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Go to iovs.org to access the version of record. For permissionto reproduce any abstract, contact the ARVO Office at arvo@arvo.org.
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