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Visual Psychophysics / Physiological Optics - ARVO

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<strong>ARVO</strong> 2013 Annual Meeting Abstracts by Scientific Section/Group – <strong>Visual</strong> <strong>Psychophysics</strong> / <strong>Physiological</strong> <strong>Optics</strong>App for vision testing illustrates the feasibility of the method. It iseasy to use even for former iPad non-users and delivers resultsconsistent with established vision testing instruments. This suggeststhat the iPad App is suitable to support patients and ophthalmologistsin the routine care of AMD. Features like an adjustable reminder anda mail function contribute to its value. The Amsler grid will beincluded and an automated distance adjustment will be implementedto further improve feasibility and reliability of the tool. Home use ofthe auto-vision App will be evaluated.Commercial Relationships: Matthias G. Hartmann, Novartis (F)Program Number: 5019 Poster Board Number: A0181Presentation Time: 2:45 PM - 4:30 PMA New Contour Integration Macular Perimetry (CIMP) on iPadfor <strong>Visual</strong> Function Evaluation in MaculopathyYi-Zhong Wang 1, 2 , Gina Mitzel 1 . 1 Retina Foundation of theSouthwest, Dallas, TX; 2 Ophthalmology, UT Southwestern MedicalCenter, Dallas, TX.Purpose: Patients with maculopathy often show early abnormalitiesoutside fovea. Such paracentral deficits may not be detected by visualfunction tests for foveal vision. In this study, a new macularperimetry based on contour integration was developed on iPad, andthe feasibility of using CIMP to detect paracentral vision loss inmaculopathy was assessed.Methods: Thirty normal subjects (mean age 51 years ± 22SD, meanvisual acuity (VA) 0.04 logMAR ± 0.08SD) and 30 patients (meanage 62±21, mean VA 0.36±0.35) with maculopathy (12 withStargardt disease, 7 diabetic maculopathy, and 11 age-related maculardegeneration) participated in the study. CIMP stimuli were circularcontour segments, and were generated on iPad screen that subtended18x23.4 deg at a viewing distance of 18”. In each trial, 4 contoursegments, each a 30 deg circular arc, were evenly placed along thecenter of the inner or outer ring of the ETDRS macular grid. Among4 segments, one was distorted and others were smooth. The distortionwas introduced by radial modulation. The stimulus duration was 0.25sec. The subject’s task was to indicate by touch which one of 4locations had distorted contour. A spatial 4-alternative, forced-choice(4AFC) staircase paradigm and a maximum likelihood fittingprocedure were employed to estimate the threshold for detectingcontour distortion in the inner or outer ring of the grid.Results: Thirty-four diseased eyes (mean VA 0.19±0.20) were ableto perform the CIMP test. Their mean thresholds to detect distortionin the inner and outer rings were -0.36±0.36 and -0.54±0.35logMAR, respectively, significantly worse than normal controls (-0.73±0.16 and -0.81±0.16, respectively, p0.16), the innerand outer ring mean thresholds were -0.36±0.39 and -0.49±0.41,respectively, also significantly worse than the normal controls(p

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