Palliative Care Guidelines - NHS Lanarkshire

Palliative Care Guidelines: McKinley T34 syringe pump drug compatibility & stability chartsCompatibility and stability charts for a subcutaneousinfusion in a McKinley T34 Syringe PumpTable 1: Subcutaneous Morphine InfusionDiluent: Water for injections• These are not clinical doses to prescribe. Most patients do not need such high doses.Read the relevant guidelines.• Use this table to check for concentrations that are stable.• Refer to the relevant guidelines to obtain the usual dose range for each of the medications. Usethe minimum effective dose and titrate according to response.Drug CombinationConcentrations of two drug combinations that arephysically stable17ml in 20ml syringe22ml in 30ml syringeMorphine SulphateCyclizineMorphine SulphateGlycopyrronium bromideMorphine SulphateHaloperidolMorphine SulphateHyoscine butylbromideMorphine SulphateHyoscine hydrobromideMorphine SulphateLevomepromazineMorphine SulphateMetoclopramideMorphine SulphateMidazolamMorphine SulphateOctreotide300mg150mg300mg1200 micrograms400mg10mg300mg120mg450mg1200 micrograms300mg100mg120mg60mg300mg30mg400mg400 micrograms160mg80mg380mg40mg500mg500 microgramsDrug CombinationConcentrations of three drug combinations that arephysically stable17ml in 20ml syringe22ml in 30ml syringeMorphine SulphateCyclizineHaloperidolMorphine SulphateHaloperidolMidazolamMorphine SulphateHyoscine butylbromideMidazolamMorphine SulphateMetoclopramideMidazolamMorphine SulphateGlycopyrroniumHaloperidol40mg100mg2.5mg100mg5mg20mg50mg40mg60mg50mg30mg7.5mg270mg1200 micrograms10mg130mg6.5mg25mg60mg50mg75mg60mg40mg10mg© NHS Lanarkshire Issue date: January 2009 Review date: March 20121