Role of Pharmacogenomics in Drug Development – An Industry ...
Role of Pharmacogenomics in Drug Development – An Industry ...
Role of Pharmacogenomics in Drug Development – An Industry ...
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Farglitazar Cl<strong>in</strong>ical Studies• Farglitazar, PPARγ agonist <strong>in</strong> Phase III studies <strong>in</strong> Type2 diabetic patients• 647/1106 (59%) subjects provided <strong>in</strong>formed consentand DNA samples for PGx analysis whilst participat<strong>in</strong>g<strong>in</strong> cl<strong>in</strong>ical studies• 555/647 (86%) were categorised as White• White subjects were allocated to three groups basedon study treatment<strong>–</strong> Farglitazar monotherapy: 6 studies (n=337)<strong>–</strong> Farglitazar plus glyburide: 1 study (n=77)<strong>–</strong> Farglitazar plus <strong>in</strong>sul<strong>in</strong>: 2 studies (n=141)
Change language