Role of Pharmacogenomics in Drug Development – An Industry ...
Role of Pharmacogenomics in Drug Development – An Industry ...
Role of Pharmacogenomics in Drug Development – An Industry ...
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Abacavir HSR Prospective PGx study• A prospective study evaluate the utility <strong>of</strong>HLA-B*5701 screen<strong>in</strong>g on Abacavir HSR rate• 6 weeks treatment with Abacavir conta<strong>in</strong><strong>in</strong>gantiviral regimens (2 x 900 patients)• Comparison <strong>of</strong> HSR rates between patients<strong>–</strong> Receiv<strong>in</strong>g current standard <strong>of</strong> care (all comers)versus<strong>–</strong> Prospective HLA-B*5701 screen<strong>in</strong>g and <strong>in</strong>clusion <strong>of</strong>marker negative patients (marker positive patientsexcluded)
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