Petechiae, Purpura and Vasculitis

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Case Five, Question 1 Answer: c • What is the most likely diagnosis? a. Henoch-Schönlein Purpura (affects small vessels) b. Erythema nodosum (panniculitis on biopsy) c. Polyarteritis nodosa (affects medium-sized arteries) d. Takayasu arteritis (affects large vessels) e. Urticaria (presents with a different morphology, which is urticarial) 74
Polyarteritis Nodosa • Polyarteritis Nodosa (PAN) is a potentially systemic disorder of necrotizing vasculitis of medium-sized arteries • Characterized by painful subcutaneous nodules, which can ulcerate • Patients may also present with livedo reticularis • Unknown etiology; may affect any organ (most often skin, peripheral nerves, kidneys, joints, and GI tract) • PAN has been associated with HBV, HCV, HIV, parvovirus B19, Crohn’s disease, strep and TB infections and medications (minocycline)
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Petechiae, Purpura and Vasculitis A
Page 3 and 4:
Purpuras • Either Non-Palpable or
Page 5 and 6:
Non-Palpable Purpura: Ecchymoses
Page 7 and 8:
Petechiae
Page 9 and 10:
Purpura: The Basics • All forms d
Page 11 and 12:
Examples of Purpura Petechia Ecchym
Page 13 and 14:
Case One 13
Page 15 and 16:
Case One: Skin Exam • Perifollicu
Page 17 and 18:
Case One, Question 1 • Which of t
Page 19 and 20:
Vitamin C Deficiency - Scurvy • S
Page 21 and 22:
Vitamin C Deficiency - Scurvy
Page 23 and 24: Case Two: History • HPI: 19-year-
Page 25 and 26: Case Two: Initial Labs • WBC coun
Page 27 and 28: Sepsis and DIC • Patient’s clin
Page 29 and 30: Meningococcemia
Page 31 and 32: Purpura Fulminans - DIC
Page 33 and 34: Rocky Mountain Spotted Fever
Page 35 and 36: Clinical Evaluation of Purpura •
Page 37 and 38: Palpable Purpura 37
Page 39 and 40: Vasculitis Morphology • Vasculiti
Page 41 and 42: Vasculitides According to Size of t
Page 43 and 44: Case Three 43
Page 45 and 46: Case Three: Skin Exam • Non-blanc
Page 47 and 48: Case Three, Question 1 Answer: d
Page 49 and 50: Case Three, Question 2 • What is
Page 51 and 52: Henoch-Schonlein Purpura • Henoch
Page 53 and 54: HSP: Evaluation and Treatment • I
Page 55 and 56: Case Four 55
Page 57 and 58: Case Four: Skin Exam • Normal vit
Page 59 and 60: Answer: b Case Four, Question 1 •
Page 61 and 62: Case Four, Question 2 Answer: a & c
Page 63 and 64: LCV: Evaluation • CBC • Urinana
Page 65 and 66: Leukocytoclastic vasculitis • Pal
Page 67 and 68: Case Five 67
Page 69 and 70: Case Five: Exam • Vitals: febrile
Page 71 and 72: Case Five: Labs • CBC: anemia •
Page 73: Case Five, Question 1 • What is t
Page 77 and 78: Polyarteritis Nodosa • Several hy
Page 79 and 80: Systemic PAN • Key diagnostic fea
Page 81 and 82: Management: PAN • Chronic course
Page 83 and 84: Pigmentary Purpuric Eruptions Varia
Page 85 and 86: Schamberg’s Disease- Treatment
Page 87 and 88: Purpura AnnularisTelangiectoides Ma
Page 89 and 90: Ducas and Kapetanakis
Page 91 and 92: Summary: Petechiae and Purpura •
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Petechiae, Purpura and Vasculitis

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