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Petechiae, Purpura and Vasculitis

Petechiae, Purpura and Vasculitis

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HSP: Diagnosis <strong>and</strong><br />

Evaluation<br />

• Diagnosis often made on clinical presentation<br />

+/- skin biopsy<br />

• Skin biopsy shows leukocytoclastic vasculitis in<br />

postcapillary venules (small vessel disease)<br />

• Immune complexes in vessel walls contain IgA<br />

deposition (the diagnostic feature of HSP)<br />

• Rule out streptococcal infection with an ASO or<br />

throat culture

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