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4060 – 4080 – <strong>Wednesday</strong> – Papers/Minisymposium<br />
4060 — 9:30 Purine Signaling in Müller<br />
Cells During Development and in the Adult<br />
Retina in Health and Disease. Antje Grosche.<br />
Pathophysiology of Neuroglia, University of<br />
Leipzig, Leipzig, Germany<br />
4061 — 9:45 Purinergic Signaling in Retinal<br />
Processing. Thomas E. Salt. Visual Neuroscience,<br />
UCL Institute of Ophthalmology, London, United<br />
Kingdom *CR<br />
4062 — 10:00 Purines and Low Grade<br />
Inflammation at Either End of the Retina; ATP<br />
and Cytokines in Both RGCs and RPE. Claire H.<br />
Mitchell. Anatomy and Cell Biology, University of<br />
Pennsylvania Library, Philadelphia, PA *CR<br />
TCC LL 4/5<br />
<strong>Wednesday</strong>, May 08, 2013 8:30 AM-10:15 AM<br />
Visual Psychophysics / Physiological Optics<br />
410 Spatial Vision, Visual<br />
Psychophysics and Aging II<br />
TCC 303<br />
<strong>Wednesday</strong>, May 08, 2013 8:30 AM-10:15 AM<br />
Cornea<br />
411 Keratoconus and Biomechanics<br />
Moderator: Shukti Chakravarti<br />
4069 — 8:30 Mutations in the zinc finger<br />
protein gene, ZNF469 contribute to the<br />
pathogenesis of keratoconus. Andrea L. Vincent 1, 2 ,<br />
C. Jordan 1, 2 , B. Hay 1 , A. J. Richards 1 , C. N.<br />
McGhee 1, 2 . 1 Ophthalmology, New Zealand National<br />
Eye Centre, University of Auckland, Auckland,<br />
New Zealand; 2 Eye Department, Greenlane Clinical<br />
Centre, Auckland District Health Board, Auckland,<br />
New Zealand *CR<br />
4070 — 8:45 Matrix Metalloproteinase-9 drives<br />
disease progression of Keratoconus. Ashwini<br />
Ranganath, R. Shetty, S. D’Souza, K. Wadia, D.<br />
Das, A. Ghosh. cornea and refractive surgery,<br />
Narayana Nethralaya eye hospital, Bangalore, India<br />
f<br />
4071 — 9:00 Novel proteins and metabolites<br />
for the identification of Keratoconus disease.<br />
Dimitrios Karamichos 1, 2 , J. Hjortdal 4 , A. E.<br />
Hutcheon 1, 2 , J. M. Asara 3 , J. D. Zieske 1, 2 .<br />
1<br />
Schepens Eye Research Institute/MEE, Boston,<br />
MA; 2 Department of Ophthalmology, Harvard<br />
Medical School, Boston, MA; 3 Division of<br />
Signal Transduction/Mass Spectrometry Core,<br />
Beth Israel Deaconess Medical Center, Harvard<br />
Medical School, Boston, MA; 4 Department of<br />
Ophthalmology, Aarhus University Hospital, Aarhus<br />
C, Denmark *CR<br />
4072 — 9:15 Evaluation of transcorneal<br />
iontophoresis of riboflavin for corneal<br />
collagen cross-linking. Alejandro Arboleda 1, 2 , L.<br />
Kowalczuk 3 , M. Savoldelli 4 , C. Klein 3 , S. Ladraa 3 ,<br />
J. A. Parel 1, 4 , F. F. Behar-Cohen 3, 4 . 1 Ophthalmic<br />
Biophysics Center, Dept. of Ophthalmology,<br />
Bascom Palmer Eye Institute, University of<br />
Miami Miller School of Medicine, Miami, FL;<br />
2<br />
Dept. of Biomedical Engineering, University<br />
of Miami College of Engineering, Coral Gables,<br />
FL; 3 INSERM UMRS872: Physiopathology of<br />
Ocular Diseases: Therapeutic Innovations, Centre<br />
de Recherche des Cordeliers, Pierre et Marie<br />
Curie University, Paris Descartes University,<br />
Paris, France; 4 AP-HP Hôtel-Dieu, Dept. of<br />
Ophthalmology, Sorbonne Paris Cité, Paris<br />
Descartes University, Faculty of Medicine, Paris,<br />
France *CR<br />
4073 — 9:30 Corneal biomechanical<br />
properties in corneal collagen cross-linking<br />
(CXL) at high fluences. Arthur Hammer 1 , O.<br />
Richoz 1 , D. Tabibian 1 , F. Hoogewoud 1 , F. Hafezi 1, 2 .<br />
1<br />
Ophthalmology, Geneva University Hospitals,<br />
Geneva, Switzerland; 2 Ophthalmology, Doheny<br />
Eye Institute, Keck school of medicine USC, Los<br />
Angeles, CA *CR<br />
4074 — 9:45 Soluble collagen protects the<br />
corneal fibrils during riboflavin crosslinking.<br />
Marcos Garza-Madrid 1, 2 , J. Elisseeff 1 .<br />
1<br />
Translational Tissue Engineering Center, Wilmer<br />
Eye Institute, Johns Hopkins School of Medicine,<br />
Baltimore, MD; 2 Ophthalmology and Visual<br />
Sciences Research Chair, School of Medicine<br />
and Health Sciences, Tecnológico de Monterrey,<br />
Monterrey, Mexico *CR<br />
4075 — 10:00 Brillouin microscopy of<br />
collagen crosslinking: non-contact depthdependent<br />
analysis of corneal elastic modulus.<br />
Giuliano Scarcelli 1 , S. Kling 2 , E. Quijano 1 , R.<br />
Pineda 3 , S. Marcos 2 , S. H. Yun 1 . 1 Wellman Center<br />
for Photomedicine, Harvard Medical School,<br />
Cambridge, MA; 2 Instituto de Optica, Conjejo<br />
Superior de investigation cientifica, Madrid, Spain;<br />
3<br />
Ophthalmology, Mass eye and ear Infirmary,<br />
Boston, MA *CR<br />
TCC 304<br />
<strong>Wednesday</strong>, May 08, 2013 8:30 AM-10:15 AM<br />
Visual Neuroscience<br />
412 Photoreceptors: Structure,<br />
Transduction, Signaling<br />
<strong>Wednesday</strong> Papers/<br />
Minisymposium<br />
8:30 am – 10:15 am<br />
Moderators: Joanne M. Wood and Heidi J. Hofer<br />
4063 — 8:30 Two-point detection and<br />
appearance in the absence of higher order<br />
aberrations. Heidi J. Hofer, D. E. Koenig. College<br />
of Optometry, University of Houston, Houston, TX<br />
4064 — 8:45 A Comparison of Acuity and<br />
Cone Density in the Temporal Retina. Nancy J.<br />
Coletta 1 , T. Y. Chui 2 , A. E. Elsner 2 . 1 Vision Science,<br />
New England College of Optometry, Boston,<br />
MA; 2 School of Optometry, Indiana University,<br />
Bloomington, IN *CR<br />
4065 — 9:00 Age-related variation in foveal,<br />
parafoveal and peripheral spatial suppression.<br />
Rigmor C. Baraas, C. Aaen-Stockdale, S. J. Gilson.<br />
Optometry & Visual Science, Buskerud University<br />
College, Kongsberg, Norway<br />
4066 — 9:15 Heterochromatic Modulation<br />
Photometry can be used to measure Macular<br />
Pigment Optical Density. Cord R. Huchzermeyer 1 ,<br />
J. Schlomberg 1 , U. Welge-Lüssen 1 , T. Berendschot 2 ,<br />
J. J. Kremers 1 . 1 Department of Ophthalmology,<br />
University Erlangen-Nuremberg, Erlangen,<br />
Germany; 2 University Eye Clinic, Maastricht,<br />
Netherlands<br />
4067 — 9:30 Comparability of Visual<br />
Performance of Individuals with Low Vision in<br />
Real and Virtual Street Intersections. Lei Liu,<br />
E. L. Bowman. School of Optometry, University of<br />
Alabama at Birmingham, Birmingham, AL<br />
4068 — 9:45 Optical quality and subjective<br />
judgments of blur under pure simultaneous<br />
vision. Carlos Dorronsoro, A. Radhakrishnan, L.<br />
Sawides, S. Marcos. Instituto de Optica, CSIC,<br />
Madrid, Spain *CR<br />
Moderators: Marie E. Burns and Wolfgang Baehr<br />
4076 — 8:30 Modulating the phototransduction<br />
cascade with small molecules. Tomoki Isayama 1 ,<br />
J. Wu 1 , S. Miyazono 1 , V. Lee 1 , E. S. Levine 1 , E.<br />
Makino 3 , A. L. Zimmerman 2 , C. L. Makino 1 .<br />
1<br />
Ophthalmology, Mass Eye & Ear Infirmary,<br />
Boston, MA; 2 Molecular Pharmacology, Physiology<br />
and Biotechnology, Brown University, Providence,<br />
RI; 3 LGCR, Sanofi Corporation, Waltham, MA<br />
4077 — 8:45 Under-expression of GAP<br />
proteins: Effect on Mouse Rod Response Decay.<br />
Gordon L. Fain 1, 2 , M. L. Woodruff 1 , C. J. Chen 3 .<br />
1<br />
Integrative Biology and Physiology, Univ of<br />
California-Los Angeles, Los Angeles, CA; 2 Jules<br />
Stein Eye Institute, UCLA, Los Angeles, CA;<br />
3<br />
Biochemistry and Molecular Biology, Virginia<br />
Commonwealth University, Richmond, VA<br />
4078 — 9:00 Light-induced translocation<br />
of RGS9-1 and Gβ5L in Mouse Rod<br />
Photoreceptors. You-Wei Peng 1 , M. Tian 1 , M. L.<br />
Zallocchi 1 , W. Wang 1 , C. J. Chen 2 , K. Palczewski 3 ,<br />
D. E. Cosgrove 1 . 1 Genetics, Boys Town Natl<br />
Research Hosp, Omaha, NE; 2 Biochemistry &<br />
Molecular Biology, Virginia Commonwealth<br />
University, Richmond, VA; 3 Pharmacology, Case<br />
Western Reserve University, Cleveland, OH *CR<br />
4079 — 9:15 Complete protein composition of<br />
the photoreceptor disc identified by label-free<br />
quantitative proteomics. Nikolai P. Skiba, V. Y.<br />
Arshavsky. Duke University, Durham, NC<br />
4080 — 9:30 Molecular Function of<br />
Peripherin-2/rds for Photoreceptor Membrane<br />
Structure. Andrew F. Goldberg, N. Khattree, L. M.<br />
Ritter. Eye Research Institute, Oakland University,<br />
Rochester Hills, MI<br />
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index.<br />
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