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Wednesday - ARVO

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4060 – 4080 – <strong>Wednesday</strong> – Papers/Minisymposium<br />

4060 — 9:30 Purine Signaling in Müller<br />

Cells During Development and in the Adult<br />

Retina in Health and Disease. Antje Grosche.<br />

Pathophysiology of Neuroglia, University of<br />

Leipzig, Leipzig, Germany<br />

4061 — 9:45 Purinergic Signaling in Retinal<br />

Processing. Thomas E. Salt. Visual Neuroscience,<br />

UCL Institute of Ophthalmology, London, United<br />

Kingdom *CR<br />

4062 — 10:00 Purines and Low Grade<br />

Inflammation at Either End of the Retina; ATP<br />

and Cytokines in Both RGCs and RPE. Claire H.<br />

Mitchell. Anatomy and Cell Biology, University of<br />

Pennsylvania Library, Philadelphia, PA *CR<br />

TCC LL 4/5<br />

<strong>Wednesday</strong>, May 08, 2013 8:30 AM-10:15 AM<br />

Visual Psychophysics / Physiological Optics<br />

410 Spatial Vision, Visual<br />

Psychophysics and Aging II<br />

TCC 303<br />

<strong>Wednesday</strong>, May 08, 2013 8:30 AM-10:15 AM<br />

Cornea<br />

411 Keratoconus and Biomechanics<br />

Moderator: Shukti Chakravarti<br />

4069 — 8:30 Mutations in the zinc finger<br />

protein gene, ZNF469 contribute to the<br />

pathogenesis of keratoconus. Andrea L. Vincent 1, 2 ,<br />

C. Jordan 1, 2 , B. Hay 1 , A. J. Richards 1 , C. N.<br />

McGhee 1, 2 . 1 Ophthalmology, New Zealand National<br />

Eye Centre, University of Auckland, Auckland,<br />

New Zealand; 2 Eye Department, Greenlane Clinical<br />

Centre, Auckland District Health Board, Auckland,<br />

New Zealand *CR<br />

4070 — 8:45 Matrix Metalloproteinase-9 drives<br />

disease progression of Keratoconus. Ashwini<br />

Ranganath, R. Shetty, S. D’Souza, K. Wadia, D.<br />

Das, A. Ghosh. cornea and refractive surgery,<br />

Narayana Nethralaya eye hospital, Bangalore, India<br />

f<br />

4071 — 9:00 Novel proteins and metabolites<br />

for the identification of Keratoconus disease.<br />

Dimitrios Karamichos 1, 2 , J. Hjortdal 4 , A. E.<br />

Hutcheon 1, 2 , J. M. Asara 3 , J. D. Zieske 1, 2 .<br />

1<br />

Schepens Eye Research Institute/MEE, Boston,<br />

MA; 2 Department of Ophthalmology, Harvard<br />

Medical School, Boston, MA; 3 Division of<br />

Signal Transduction/Mass Spectrometry Core,<br />

Beth Israel Deaconess Medical Center, Harvard<br />

Medical School, Boston, MA; 4 Department of<br />

Ophthalmology, Aarhus University Hospital, Aarhus<br />

C, Denmark *CR<br />

4072 — 9:15 Evaluation of transcorneal<br />

iontophoresis of riboflavin for corneal<br />

collagen cross-linking. Alejandro Arboleda 1, 2 , L.<br />

Kowalczuk 3 , M. Savoldelli 4 , C. Klein 3 , S. Ladraa 3 ,<br />

J. A. Parel 1, 4 , F. F. Behar-Cohen 3, 4 . 1 Ophthalmic<br />

Biophysics Center, Dept. of Ophthalmology,<br />

Bascom Palmer Eye Institute, University of<br />

Miami Miller School of Medicine, Miami, FL;<br />

2<br />

Dept. of Biomedical Engineering, University<br />

of Miami College of Engineering, Coral Gables,<br />

FL; 3 INSERM UMRS872: Physiopathology of<br />

Ocular Diseases: Therapeutic Innovations, Centre<br />

de Recherche des Cordeliers, Pierre et Marie<br />

Curie University, Paris Descartes University,<br />

Paris, France; 4 AP-HP Hôtel-Dieu, Dept. of<br />

Ophthalmology, Sorbonne Paris Cité, Paris<br />

Descartes University, Faculty of Medicine, Paris,<br />

France *CR<br />

4073 — 9:30 Corneal biomechanical<br />

properties in corneal collagen cross-linking<br />

(CXL) at high fluences. Arthur Hammer 1 , O.<br />

Richoz 1 , D. Tabibian 1 , F. Hoogewoud 1 , F. Hafezi 1, 2 .<br />

1<br />

Ophthalmology, Geneva University Hospitals,<br />

Geneva, Switzerland; 2 Ophthalmology, Doheny<br />

Eye Institute, Keck school of medicine USC, Los<br />

Angeles, CA *CR<br />

4074 — 9:45 Soluble collagen protects the<br />

corneal fibrils during riboflavin crosslinking.<br />

Marcos Garza-Madrid 1, 2 , J. Elisseeff 1 .<br />

1<br />

Translational Tissue Engineering Center, Wilmer<br />

Eye Institute, Johns Hopkins School of Medicine,<br />

Baltimore, MD; 2 Ophthalmology and Visual<br />

Sciences Research Chair, School of Medicine<br />

and Health Sciences, Tecnológico de Monterrey,<br />

Monterrey, Mexico *CR<br />

4075 — 10:00 Brillouin microscopy of<br />

collagen crosslinking: non-contact depthdependent<br />

analysis of corneal elastic modulus.<br />

Giuliano Scarcelli 1 , S. Kling 2 , E. Quijano 1 , R.<br />

Pineda 3 , S. Marcos 2 , S. H. Yun 1 . 1 Wellman Center<br />

for Photomedicine, Harvard Medical School,<br />

Cambridge, MA; 2 Instituto de Optica, Conjejo<br />

Superior de investigation cientifica, Madrid, Spain;<br />

3<br />

Ophthalmology, Mass eye and ear Infirmary,<br />

Boston, MA *CR<br />

TCC 304<br />

<strong>Wednesday</strong>, May 08, 2013 8:30 AM-10:15 AM<br />

Visual Neuroscience<br />

412 Photoreceptors: Structure,<br />

Transduction, Signaling<br />

<strong>Wednesday</strong> Papers/<br />

Minisymposium<br />

8:30 am – 10:15 am<br />

Moderators: Joanne M. Wood and Heidi J. Hofer<br />

4063 — 8:30 Two-point detection and<br />

appearance in the absence of higher order<br />

aberrations. Heidi J. Hofer, D. E. Koenig. College<br />

of Optometry, University of Houston, Houston, TX<br />

4064 — 8:45 A Comparison of Acuity and<br />

Cone Density in the Temporal Retina. Nancy J.<br />

Coletta 1 , T. Y. Chui 2 , A. E. Elsner 2 . 1 Vision Science,<br />

New England College of Optometry, Boston,<br />

MA; 2 School of Optometry, Indiana University,<br />

Bloomington, IN *CR<br />

4065 — 9:00 Age-related variation in foveal,<br />

parafoveal and peripheral spatial suppression.<br />

Rigmor C. Baraas, C. Aaen-Stockdale, S. J. Gilson.<br />

Optometry & Visual Science, Buskerud University<br />

College, Kongsberg, Norway<br />

4066 — 9:15 Heterochromatic Modulation<br />

Photometry can be used to measure Macular<br />

Pigment Optical Density. Cord R. Huchzermeyer 1 ,<br />

J. Schlomberg 1 , U. Welge-Lüssen 1 , T. Berendschot 2 ,<br />

J. J. Kremers 1 . 1 Department of Ophthalmology,<br />

University Erlangen-Nuremberg, Erlangen,<br />

Germany; 2 University Eye Clinic, Maastricht,<br />

Netherlands<br />

4067 — 9:30 Comparability of Visual<br />

Performance of Individuals with Low Vision in<br />

Real and Virtual Street Intersections. Lei Liu,<br />

E. L. Bowman. School of Optometry, University of<br />

Alabama at Birmingham, Birmingham, AL<br />

4068 — 9:45 Optical quality and subjective<br />

judgments of blur under pure simultaneous<br />

vision. Carlos Dorronsoro, A. Radhakrishnan, L.<br />

Sawides, S. Marcos. Instituto de Optica, CSIC,<br />

Madrid, Spain *CR<br />

Moderators: Marie E. Burns and Wolfgang Baehr<br />

4076 — 8:30 Modulating the phototransduction<br />

cascade with small molecules. Tomoki Isayama 1 ,<br />

J. Wu 1 , S. Miyazono 1 , V. Lee 1 , E. S. Levine 1 , E.<br />

Makino 3 , A. L. Zimmerman 2 , C. L. Makino 1 .<br />

1<br />

Ophthalmology, Mass Eye & Ear Infirmary,<br />

Boston, MA; 2 Molecular Pharmacology, Physiology<br />

and Biotechnology, Brown University, Providence,<br />

RI; 3 LGCR, Sanofi Corporation, Waltham, MA<br />

4077 — 8:45 Under-expression of GAP<br />

proteins: Effect on Mouse Rod Response Decay.<br />

Gordon L. Fain 1, 2 , M. L. Woodruff 1 , C. J. Chen 3 .<br />

1<br />

Integrative Biology and Physiology, Univ of<br />

California-Los Angeles, Los Angeles, CA; 2 Jules<br />

Stein Eye Institute, UCLA, Los Angeles, CA;<br />

3<br />

Biochemistry and Molecular Biology, Virginia<br />

Commonwealth University, Richmond, VA<br />

4078 — 9:00 Light-induced translocation<br />

of RGS9-1 and Gβ5L in Mouse Rod<br />

Photoreceptors. You-Wei Peng 1 , M. Tian 1 , M. L.<br />

Zallocchi 1 , W. Wang 1 , C. J. Chen 2 , K. Palczewski 3 ,<br />

D. E. Cosgrove 1 . 1 Genetics, Boys Town Natl<br />

Research Hosp, Omaha, NE; 2 Biochemistry &<br />

Molecular Biology, Virginia Commonwealth<br />

University, Richmond, VA; 3 Pharmacology, Case<br />

Western Reserve University, Cleveland, OH *CR<br />

4079 — 9:15 Complete protein composition of<br />

the photoreceptor disc identified by label-free<br />

quantitative proteomics. Nikolai P. Skiba, V. Y.<br />

Arshavsky. Duke University, Durham, NC<br />

4080 — 9:30 Molecular Function of<br />

Peripherin-2/rds for Photoreceptor Membrane<br />

Structure. Andrew F. Goldberg, N. Khattree, L. M.<br />

Ritter. Eye Research Institute, Oakland University,<br />

Rochester Hills, MI<br />

The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index.<br />

272

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