Wednesday - ARVO

Wednesday – Posters – 5229 – 5251
5229 — C0148 A Long-Lasting Scar in Murine
Cornea. Andrew Hertsenberg, S. Basu, Y. Du, J.
L. Funderburgh. Ophthalmology, University of
Pittsburgh School of Medicine, Pittsburgh, PA
5230 — C0149 Autologous Platelet Rich
Plasma Therapy in Resistant Corneal Ulcers.
Yakup Aksoy 1 , U. Erdem 2 . 1 Ophthalmology, Gülhane
Military Medical Academy Haydarpasa Education
Hospital, istanbul, Turkey; 2 Ophthalmology,
Gülhane Military Medical Faculty, Ankara, Turkey
5231 — C0150 Initial Evidence that Immune
Cell Infiltrates are Candidate Sources of Post-
Surface Ablation Stromal Roughening. Daniel J.
Gibson, G. S. Schultz. Obstetrics and Gynecology,
University of Florida, Gainesville, FL
5232 — C0151 Outcomes of Traumatic
Dehiscence of Penetrating Keratoplasty versus
Severe Open-Globe Injury. Therese Peron,
M. A. Woodward, R. M. Shtein. Department of
Ophthalmology, University of Michigan, Ann
Arbor, MI
5233 — C0152 Proteomic analysis of the
interaction Fusarium solani - Staphylococcus
epidermidis isolated from human corneal
ulcers. Mariana Ortiz-Casas 1 , A. V. Rodríguez-
Tovar 2 , J. Reyes-Grajeda 3 , H. Mejia-Lopez 1 , M.
A. Martínez-Rivera 2 , L. A. Bautista-Hernández 1 ,
C. Gaona-Juárez 1 , N. López-Espinosa 1 , V. M.
Bautista 1 . 1 Microbiology and Proteomics, Institute
of Opthalmology “Conde de Valenciana”, Mexico
City, Mexico; 2 Medical Mycology, Escuela
Nacional de Ciencias Biológicas, IPN, Mexico
City, Mexico; 3 Medical Proteomics Unit, Instituto
Nacional de Medicina Genómica, Mexico City,
Mexico
5234 — C0153 Collagen vitrigels for cornea
reconstruction: collagen source and crosslinking.
Shoumyo Majumdar 1, 2 , M. Garza-Madrid 2, 3 , X.
Calderon-Colon 4 , M. Trexler 4 , O. D. Schein 5 ,
J. Elisseeff 1, 2 . 1 Biomedical Engineering, Johns
Hopkins University, Baltimore, MD; 2 Translational
Tissue Engineering Center, Wilmer Eye Institute,
Johns Hopkins School of Medicine, Baltimore,
MD; 3 Ophthalmology and Visual Sciences
Research Chair, School of Medicine and Health
Sciences, Tecnológico de Monterrey, Monterrey,
Mexico; 4 Applied Physics Laboratory, Johns
Hopkins University, Laurel, MD; 5 Department
of Ophthalmology, Wilmer Eye Institute, Johns
Hopkins School of Medicine, Baltimore, MD *CR
5235 — C0154 A Role for Macrophage-derived
Interleukin-20 in Mouse Corneal Epithelial
Wound Healing. Wanyu Zhang 1 , C. W. Smith 2 ,
Z. Li 2 , A. R. Burns 1, 2 . 1 College of Optometry,
University of Houston, Houston, TX; 2 Pediatricsleukocyte
biology, Baylor College of Medicine,
Houston, TX
5236 — C0155 The Effects of Amniotic
Membrane Extract on Primary Human Corneal
Epithelial Cells. David V. Dudok 1 , K. Cheung 1 ,
H. Liu 1 , L. Vedovelli 3 , E. Ghinelli 2 , K. Kenyon 2 ,
S. Parapuram 1 , C. M. Hutnik 1 . 1 Ophthalmology,
Western University Canada, London, ON, Canada;
2
Ophthalmology, Massachusetts Eye & Ear
Infirmary, Boston, MA; 3 Division of Nephrology,
Cell Biology, Human Biology and Physiology,
Massachusetts General Hospital, Boston, MA
5237 — C0156 Sex-Specific Differences in the
Corneal Inflammatory Reparative Response via
Estrogen Modulation of Phagocytosis. Samantha
B. Wang, K. M. Hu, Y. Wang, D. W. Lin, J. Jong,
J. Lai, K. Gronert. Vision Science Program,
University of California, Berkeley, Oakland, CA
Exhibit Hall C0157-C0177
Wednesday, May 08, 2013 2:45 PM-4:30 PM
Cornea
476 Corneal Stroma and Keratocytes
Moderator: Holly B. Hindman
5238 — C0157 Keratocyte-Keratocyte
Translamellar Connectivity in the Mouse Cornea
is Revealed using a Novel 3-D Ultrastructural
Approach. Samuel D. Hanlon 1 , N. C. Shenoi 1 ,
P. T. Harris 1 , P. T. Landry 1 , A. R. Behzad 2 , E. S.
Brown 1 , M. M. Gondo 1 , A. R. Burns 1, 3 . 1 Research,
Univ of Houston College of Optometry, Houston,
TX; 2 Imaging and Characterization Core Lab, King
Abdullah University of Science and Technology,
Thuwal, Saudi Arabia; 3 Leukocyte Biology, Baylor
College of Medicine, Houston, TX
5239 — C0158 Effect of Serum Clot Activator
on Keratocytes. Ji-Eun Lee 1 , S. Lee 2 , J. Lee 1 .
1
Ophthalmology, Pusan National University,
Pusan, Republic of Korea; 2 Ophthalmology, Kosin
University, Pusan, Republic of Korea
5240 — C0159 Co-cultures of Human Corneal
Epithelium and Self-assembled Keratocyte
and Fibroblast Matrix. Audrey E. Hutcheon 1, 2 ,
D. Karamichos 1, 2 , X. Q. Guo 1, 2 , J. D. Zieske 1, 2 .
1
Schepens Eye Research Institute/MEE, Boston,
MA; 2 Department of Ophthalmology, Harvard
Medical School, Boston, MA
5241 — C0160 RNAi Gene Silencing Of TGFbeta
Signaling: A Powerful Approach To Control
Corneal Fibrosis. Jason T. Rodier, A. Sharma,
A. Tandon, A. Stallard, R. R. Mohan. Mason
Eye Institute, University of Missouri-Columbia,
Columbia, MO
5242 — C0161 Up-Regulation of Apoptotic
Markers Following β-Actin Gene-Silencing
in Corneal Stromal Fibroblasts. Roy Joseph 1 ,
O. P. Srivastava 1 , R. R. Pfister 2 . 1 Department of
Vision Sciences, Univ of Alabama at Birmingham,
Birmingham, AL; 2 Eye Research Foundation,
Birmingham, AL
5243 — C0162 Collective Spreading and
Migration of Corneal Fibroblasts in Fibrin
Matrices are not Dependent on Increased Cell
Contractility. Miguel Miron Mendoza, M. Petroll.
Ophthalmology, Univ of Texas Southwestern Med
Ctr, Dallas, TX
f Refer to the Program Number in the Clinical Trial (CT) Registration Index. *CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.
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5244 — C0163 Alarmin from corneal epithelial
cells synergizes with Th2 cytokines on the
expression of CCL11 and VCAM-1 by corneal
fibroblasts. Ken Fukuda 1 , H. Tanaka 2 , W. Ishida 1 ,
Y. Harada 1 , T. Sumi 1 , A. Matsuda 3 , N. Ebihara 3 ,
A. Fukushima 1 . 1 Ophthalmology, Kochi Medical
School, Nankoku, Japan; 2 Ophthalmology, Machida
Hospital, Kochi, Japan; 3 Ophthalmology, Juntendo
University School of Medicine, Tokyo, Japan *CR
5245 — C0164 Mitomycin C Suppresses
Gene Splicing in Corneal Fibroblasts. Tsan-Chi
Chen 1 , S. Chang 1, 2 , C. Lee 1 , H. Teng 1 . 1 Department
of Ophthalmology, Far Eastern Memorial
Hospital, New Taipei City, Taiwan; 2 Department
of Ophthalmology, National Taiwan University
Hospital, Taipei, Taiwan f
5246 — C0165 The anti-fibrotic Halofuginone
regulates the expression of Egr-1 in human
corneal fibroblasts. Ching Yuan, M. Twite, E. F.
Nelson. Ophthalmology and Visual Neurosciences,
University of Minnesota, Minneapolis, MN
5247 — C0166 Effect of TGF-β1 and 3 on
protein expression in human corneal fibroblasts.
Xiaoqing Q. Guo 1, 2 , A. E. Hutcheon 1, 2 , J. D.
Zieske 1, 2 . 1 Schepens Eye Research Institute/MEE,
Boston, MA; 2 Department of Ophthalmology,
Harvard Medical School, Boston, MA
5248 — C0167 Thrombin regulates Cyr61
synthesis and processing in cultured human
corneal stromal fibroblasts and myofibroblasts.
Emily A. Andreae 1 , D. J. Warejcka 1 , S. S. Twining 2 .
1
Biochemistry, The Medical College of Wisconsin,
Milwaukee, WI; 2 Biochemistry and Ophthalmology,
The Medical College of Wisconsin, Milwaukee, WI
5249 — C0168 Trichostatin A inihibits TGFβ-induced
reactive oxygen species accumulation
and myofibroblast differentiation via enhanced
Nrf2-ARE signaling. Qingjun Zhou, L. Yang, M.
Qu. Shandong Eye Institute, Qingdao, China
5250 — C0169 Exploring cell plasticity: the
corneal keratocyte and beyond. Carol A. Greene,
T. Sherwin, C. R. Green. Ophthalmology, University
of Auckland, Auckland, New Zealand
5251 — C0170 Reprogramming Genes Are
Expressed during Spheroidal Culture of Corneal
Stromal Cells. Yong-Soo Byun, L. Yco, B. Shaheen,
A. Sharma, S. Chaudhary, S. Gandhi, S. H. Jassim,
J. Sarkar, S. Tibrewal, S. Jain. Ophthalmology and
Visual Sciences, University of Illinois at Chicago,
Chicago, IL *CR
Wednesday Posters
2:45 pm – 4:30 pm