Wednesday - ARVO

5205– 5228 – Wednesday – Posters
Wednesday Posters
2:45 pm – 4:30 pm
5205 — C0020 Segmentation and Analysis
of Retinal Layers in Eyes with Uveitis and
Comparison with Normal. Syed Mahmood A.
Shah, Y. J. Sepah, M. A. Sadiq, S. Kherani, M.
A. Ibrahim, Z. S. Rentiya, M. Ansari, D. V. Do,
Q. Nguyen. Wilmer Eye Institute, Johns Hopkins
University, Baltimore, MD *CR
5206 — C0021 Predictive Value of Angiotensin
Converting Enzyme, Soluble Interleukin-2
Receptor and Lysozyme for Pulmonary
Involvement in Human Ocular Sarcoidosis.
Rafael Grajewski 1 , W. Adler 2 , K. Frank 3 , M.
Arfaoui 1 , S. L. Schlereth 1 , B. Kirchhof 1 , C.
Cursiefen 1 , L. M. Heindl 1 . 1 Ophthalmology,
University of Cologne, Cologne, Germany;
2
Medical Informatics, Biometry and Epidemiology,
Friedrich-Alexander University Erlangen-Nürnberg,
Erlangen, Germany; 3 Internal Medicine III,
University of Cologne, Cologne, Germany *CR
Exhibit Hall C0126-C0141
Wednesday, May 08, 2013 2:45 PM-4:30 PM
Immunology/Microbiology
474 Corneal Infection/Inflammation I
Moderator: Robert M. Shanks
5207 — C0126 MyD88-dependent and
-independent antimicrobial activity in mouse
corneas induced by Pseudomonas aeruginosa
antigen challenge. Suzanne M. Fleiszig, D. J.
Evans, C. Tam. School of Optometry, Univ of
California - Berkeley, Berkeley, CA *CR
5208 — C0127 An Experimental Model
of Biofilm Formation in the Mouse Cornea.
Padmanabhan Saraswathi, T. T. Aung, S. Salleh, R.
W. Beuerman. Singapore Eye Research Institute,
Singapore, Singapore *CR
5209 — C0128 The role of autophagy in
Pseudomonas aeruginosa keratitis. Xiaoyu Jiang,
S. A. McClellan, R. P. Barrett, Y. Zhang, M. E.
Foldenauer, K. Vistisen, L. D. Hazlett. Department
of Anatomy and Cell Biology, Wayne State
University School of Medicine, Detroit, MI
5210 — C0129 Toll-like receptor 4: A regulator
of apoptosis in the infected cornea. Sharon A.
McClellan, X. Jiang, Y. Zhang, K. Vistisen, R. P.
Barrett, L. D. Hazlett. Anatomy & Cell Biology,
Wayne State Univ School of Med, Detroit, MI
5211 — C0130 Galectin-1-Mediated
Suppression of Th17 Cell-Induced Corneal
Immunopathology post Pseudomonas aeruginosa
Infection. Amol Suryawanshi 1 , Z. Cao 1 , T. S. Zaidi 2 ,
N. A. Panjwani 1 . 1 New England Eye Center and
Department of Ophthalmology, Tufts University
School of Medicine, Boston, MA; 2 Department of
Medicine, Brigham and Women’s Hospital, Boston,
MA
5212 — C0131 In Vivo Efficacy of Keratin-
Derived Antimicrobial Peptides (KDAMPs)
in Corneal Defense Against Pseudomonas
aeruginosa. Connie Tam. School of Optometry,
Univ of California, Berkeley, Berkeley, CA *CR
5213 — C0132 Proteomic Analysis of the
Keratitis Associated Pseudomonas aeruginosa.
Abby L. Sewell, J. J. Dunmire, M. Wehmann, R.
Bouhenni. Ophthalmology Research, Summa Health
System, Akron, OH
5214 — C0133 Pseudomonas aeruginosa uses
type three secretion-dependent and -independent
mechanisms for traversal of multilayered corneal
epithelia. Aaron B. Sullivan 1 , V. Hritonenko 1 , C.
Tam 1 , D. J. Evans 2 , S. M. Fleiszig 1 . 1 School of
Optometry, UC Berkeley, Berkeley, CA; 2 College
of Pharmacy, Turo University- California, Vellejo,
CA *CR
5215 — C0134 ExoS, a type III secreted toxin,
is produced intracellularly by P. aeruginosa after
corneal epithelial cell invasion, and is triggered
by exposure to cell lysates. Victoria Hritonenko 1 ,
A. L. Jolly 1 , C. Maloney 2 , A. Farfel 3 , D. J. Evans 1, 4 ,
S. M. Fleiszig 1 . 1 School of Optometry, University of
California, Berkeley, CA; 2 Dept. of Environmental
Science, Policy, and Management, University of
California, Berkeley, AR; 3 Dept. of Molecular &
Cell Biology, University of California, Berkeley,
CA; 4 College of Pharmacy, Touro University
California, Vallejo, CA *CR
5216 — C0135 VIP Treatment of Bacterial
Keratitis Against Multiple Pseudomonas Strains.
Elizabeth A. Berger, L. D. Hazlett. Anatomy & Cell
Biology, Wayne State Univ Sch of Med, Detroit, MI
5217 — C0136 IL-1R and TLR-5 mediate
corneal epithelial defense against Pseudomonas
aeruginosa colonization and traversal
respectively. David J. Evans 1, 2 , C. Tam 2 , S. M.
Fleiszig 2 . 1 College of Pharmacy, Touro University
California, Vallejo, CA; 2 School of Optometry, UC
Berkeley, Berkeley, CA *CR
5218 — C0137 Microbiological and electron
microscopic assessment of Pseudomonas
aeruginosa infection of primary human corneal
fibroblasts and epithelial cells in-vitro. Ahmad
Elsahn 1, 2 , P. Hossain 2, 1 , M. Christodoulides 1 .
1
Molecular Microbiology, University of
Southampton, Southampton, United Kingdom;
2
Southampton Eye Unit, University Hospitals
Southampton NHS Foundation Trust, Southampton,
United Kingdom
5219 — C0138 Cystic Fibrosis Transmembrane
conductance Regulator (CFTR) competes with
Pseudomonas aeruginosa Type 3 Secretion
System (T3SS) to direct the fate of intracellular
bacteria. Amber L. Jolly 1 , S. A. Whiteside 1 , D. J.
Evans 2, 1 , S. M. Fleiszig 1 . 1 Vision Sciences, UC
Berkeley, Berkeley, CA; 2 College of Pharmacy,
Touro University, Vallejo, CA *CR
5220 — C0139 Impediment of corneal cell
migration by a Serratia marcescens factor in an
in vitro wound healing model. Kimberly Brothers,
N. A. Stella, J. Klarlund, R. M. Shanks. University
of Pittsburgh, Pittsburgh, PA *CR
5221 — C0140 Isolation of Two Proteases
from Streptococcus pneumoniae that Cause
Corneal Erosions. Mary E. Marquart, S. D.
Taylor. Microbiology, Univ of Mississippi Med Ctr,
Jackson, MS
5222 — C0141 Genomics of the Conjunctival
Pathogen Streptococcus pneumoniae. Michael
Valentino 1 , W. Haas 2 , C. M. Sanfilippo 2 , J. W.
Rosch 3 , E. I. Tuomanen 3 , T. W. Morris 2 , M. S.
Gilmore 1 . 1 Harvard Medical School / Mass. Eye
& Ear Infirmary, Boston, MA; 2 Bausch & Lomb,
Inc., Rochester, NY; 3 St. Jude Children’s Research
Hospital, Memphis, TN *CR
Exhibit Hall C0142-C0156
Wednesday, May 08, 2013 2:45 PM-4:30 PM
Cornea / Biochemistry/Molecular Biology
475 Corneal Wound Repair,
Transparency II
Moderator: Shizuya Saika
5223 — C0142 MicroRNA signature in wound
healing following excimer laser ablation:
Role of miR-133b on TGF- β, CTGF, collagen
and smooth muscle actin synthesis in corneal
fibroblast. Paulette M. Robinson 1, 2 , T. Chuang 1 , S.
Sriram 1 , L. Pi 1 , X. Luo 1 , B. Petersen 2 , G. S. Schultz 1 .
1
OB-GYN, University of Florida, Gainesville, FL;
2
Pediatrics, University of Florida, Gainesville, FL
5224 — C0143 Long-term visual outcomes
in the Steroids for Corneal Ulcers Trial. Scott
M. McClintic 1 , S. M. McClintic 1 , N. V. Prajna 2 ,
M. Srinivasan 2 , J. Mascarenhas 2 , L. Prajna 2 ,
T. Porco 1, 3 , N. Acharya 1, 3 , T. M. Lietman 1, 3 , J.
D. Keenan 1, 3 . 1 Ophthalmology, University of
California, San Francisco, San Francisco, CA;
2
Cornea and External Diseases, Aravind Eye Care
System, Madurai, India, Madurai, India; 3 Francis I.
Proctor Foundation, University of California, San
Francisco, San Francisco, CA *CR
5225 — C0144 The Effect of Local Rock-
Inhibition on Corneal Scarring After Alkali
Burn Injury. Davine Sijnave 1 , K. P. Hollanders 1 ,
T. Van Bergen 1 , S. Van de Velde 1 , E. Vandewalle 1 ,
L. K. Moons 2 , D. Leysen 3 , I. Stalmans 1 . 1 Lab of
Ophthalmology, KULeuven, Leuven, Belgium;
2
Department of Biology, KULeuven, Leuven,
Belgium; 3 Amakem Therapeutics, Diepenbeek,
Belgium *CR
5226 — C0145 Abnormal epithelial basement
membrane ultrastructure in corneas with haze
after PRK in rabbits. Andre A. Torricelli 1, 2 , V.
Singh 1 , V. Agrawal 1 , S. E. Wilson 1 . 1 Ophthalmology,
Cleveland Clinic, Cleveland, OH; 2 Ophthalmology,
FMUSP, Sao Paulo, Brazil *CR
5227 — C0146 Substance P potentiates
Anti-Fas induced apoptosis in human corneal
fibroblasts. Peter Boman 1, 2 , S. Le Roux 1 , P.
Danielson 1, 2 . 1 Anatomy, Umeå University, Umeå,
Sweden; 2 Dept. of Clinical Science, Ophthalmology,
Umeå Univeristy, Umeå, Sweden
5228 — C0147 TGF-β1 modulates the
functional expression of the NK-1 receptor in
human corneal fibroblasts. Sandrine LE ROUX, P.
Boman, P. Danielson. Anatomy, Dept. of Integrative
Medical Biology, Anatomy, Umeå University,
Umeå, Sweden
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index.
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