Wednesday - ARVO

4985 – 5004 – Wednesday – Posters
Wednesday Posters
2:45 pm – 4:30 pm
Exhibit Hall A0114-A0145
Wednesday, May 08, 2013 2:45 PM-4:30 PM
Biochemistry/Molecular Biology
466 AMD II, BI
Moderator: Alecia K. Gross
4985 — A0114 Comparison of the Gene
Expression by Haplogroups H and J:
Implications for AMD (Age Related Macular
Degeneration). Claudio A. Ramirez 1 , M. Chwa 1 ,
S. Atilano 1 , D. Malik 1 , J. Cáceres del Carpio 1 ,
M. Tarek 1 , S. Jazwinski 2 , M. V. Michael 2 , B. D.
Kuppermann 1 , C. M. Kenney 1 . 1 Gavin Herbert Eye
Institute, University of California, Irvine, Irvine,
CA; 2 Tulane Center for Aging, Tulane University,
New Orleans, LA *CR
4986 — A0115 Hops Extract Xanthohumol
Protects Visual Acuity and Function After Light
Damage. Stephanie L. Foster, N. F. Henneman,
M. A. Chrenek, C. B. Wright, J. H. Boatright.
Ophthalmology, Emory Univ School of Med,
Atlanta, GA
4987 — A0116 Role of Apoptotic Regulatory
Proteins in Retinoblastoma. Lata Singh 1 , S.
Kashyap 1 , N. Pushker 2 , S. Sen 1 , S. Bakhshi 3 , A.
Sharma 4 , N. Saini 5 , J. Kaur 6 . 1 Ocular Pathology,
All India Institute of Medical Sciences, New
Delhi, India; 2 Ophthalmology, All India Institute
of Medical Sciences, New Delhi, India; 3 Medical
Oncology, IRCH, All India Institute of Medical
Sciences, New Delhi, India; 4 Ocular Microbiology,
All India Institute of Medical Sciences, New Delhi,
India; 5 Biochemistry, Institute of Genomics and
Integrative Biology, Mall Road, New Delhi, India;
6
Ocular Biochemistry, All India Institute of Medical
Sciences, New Delhi, India
4988 — A0117 Comparison Study of IL-33
Gene Expression in Haplogroup H, J, L, and K
Cybrids. Thomas A. Vo 1 , M. Chwa 1 , S. Atilano 1 ,
D. Malik 1 , C. A. Ramirez 1 , J. Cáceres del Carpio 1 ,
S. Jazwinski 2 , M. V. Michael 2 , B. D. Kuppermann 1 ,
C. M. Kenney 1 . 1 Opthalmology, Gavin Herbert Eye
Institute at UC Irvine, Irvine, CA; 2 Tulane Center
for Aging at Tulane University, New Orleans, LA
*CR
4989 — A0118 Resveratrol Protects
Human Retinal Pigment Epithelial Cells
from Inflammatory Insults. R K. Kutty 1 ,
C. N. Nagineni 1 , W. Samuel 1 , T. Duncan 1 , C.
Vijayasarathy 2 , C. Jaworski 1 , T. Redmond 1 .
1
National Eye Institute, National Institutes of
Health, Bethesda, MD; 2 National Institute on
Deafness and Other Communication Disorders,
National Institutes of Health, Bethesda, MD
4990 — A0119 Bone morphogenetic protein
4 induces ID1 and ID3 transcription factors in
trabecular meshwork cells. Avani A. Mody, R.
J. Wordinger, A. F. Clark. Visual sicence /NTERI,
UNTHSC, Fort Worth, TX *CR
4991 — A0120 The proteolytic activity of
HTRA1 is responsible for its pathological role
in polypoidal choroidal vasculopathy. Sandeep
Kumar 1, 2 , A. Jones 1, 2 , Z. Berriochoa 2 , S. Wang 2 , Y.
Fu 1, 2 . 1 Moran Center for Translational Medicine,
University of Utah, Salt Lake City, UT; 2 Dept of
Ophthalmology and Visual Sciences, University of
Utah, Salt Lake City, UT *CR
4992 — A0121 Associations between Posterior
Vitreous Detachment and Concentrations of
Various Cytokines in Eyes with Age-related
Macular Degeneration and Normal Control
Eyes. Hidenori Takahashi 1 , X. Tan 2 , Y. Nomura 2 ,
A. Iriyama 2 , Y. Fujino 3 , Y. Okubo 1 , A. Sato 1 ,
M. Takezawa 1 , H. Kawashima 1 , Y. Yanagi 2 .
1
Ophthalmology, Jichi Medical University,
Shimotsuke-shi, Japan; 2 Ophthalmology, University
of Tokyo, Tokyo, Japan; 3 Ophthalmology, Tokyo
KoseiNenkin Hospital, Tokyo, Japan
4993 — A0122 Quantitative Proteomic
Identification of Novel Interacting Partners
for the Serine Protease Htra1. Lili Feng 1 , E.
Kortvely 1 , A. Vogt 1 , K. Boldt 1 , M. Ueffing 1, 2 . 1 Center
of Ophthalmology, University of Tuebingen,
Tuebingen, Germany; 2 Research Unit for Protein
Science, Helmholtz Zentrum München, Neuherberg,
Germany
4994 — A0123 Amyloid Beta 1- 42 Promotes
NLRP3-inflammasome Activation In Retinal
Pigmented Epithelial Cells. Matthew West 1 ,
F. Lamoke 1 , A. Montemari 2 , G. Parisi 3 , G.
Ripandelli 3 , D. M. Marcus 4 , M. Bartoli 1 .
1
Department of Ophthalmology, Georgia Health
Sciences University, Augusta, GA; 2 Department of
Experimental Medicine and Pathology, University
of Rome, Rome, Italy; 3 IRCCS Fondazione GB
Bietti, Rome, Italy; 4 Southeast Retina Center,
Augusta, GA *CR
4995 — A0124 Conditional ablation of
VEGFR-1 in photoreceptors induces retinal
angiomatous proliferation: A transgenic mouse
model of AMD. Ling Luo 1, 2 , X. Zhang 1 , S. K. Das 1 ,
H. Uehara 1 , T. Miya 1 , T. Olsen 1 , B. Archer 1 , Y.
Fu 1 , W. Baehr 1 , B. K. Ambati 1 . 1 Moran eye center,
University of Utah, Salt lake city, UT; 2 Department
of Ophthalmology, The 306th hospital of PLA,
China, Beijing, China *CR
4996 — A0125 In-depth analysis of blood
plasma proteome for discovery of age-related
macular degeneration biomarkers. Se Joon
Woo 1, 2 , H. Kim 3 , E. Suh 3 , J. Park 1, 2 , J. Ahn 1, 2 ,
D. Hwang 1, 2 , J. Lee 3 , K. Park 1, 2 , C. Lee 3, 4 .
1
Ophthalmology, Seoul National University
College of Medicine, Seoul, Republic of Korea;
2
Ophthalmology, Seoul National University
Bundang Hospital, Seongnam, Republic of Korea;
3
Theragnosis Research Center, Korea Institute of
Science and Technology, Seoul, Republic of Korea;
4
Biomolecular Science, University of Science and
Technology, Daejeon, Republic of Korea
4997 — A0126 Post-Transcriptional Gene
Interactions in Retinal Ischemia. Kalina
Andreeva, M. Soliman, N. G. Cooper. Anatomical
Sciences & Neurobiology, University of Louisville
School of Medicine, Louisville, KY
4998 — A0127 An In-Vitro Study of Wnt
Pathway Modulation in Cybrid H and J
Mitochondrial Haplogroups and the Possible
Implications for Age-related Macular
Degeneration. Payam Falatoonzadeh 1 , G. B. Woo 1 ,
N. Udar 1 , S. Atilano 1 , M. Chwa 1 , M. V. Michael 2 , S.
Jazwinski 2 , C. M. Kenney 1 . 1 Ophthalmology, Gavin
Herbert Eye Inst., UC Irvine, Irvine, CA; 2 Tulane
Center for Aging, Tulane University, New Orleans,
LA *CR
4999 — A0128 Expression of VEGF-C,
VEGF-D and their Cognate Receptors in
Experimental Choroidal Neovascularization
and Clinical AMD. Kameran Lashkari 1 , J. Ma 1 ,
G. Teague 1 , J. G. Arroyo 2 . 1 Schepens Eye Research
Institute/ Massachusetts Eye & Ear, Harvard Med
School, Boston, MA; 2 Beth Israel Deaconess
Medical Center, Harvard Med School, Boston, MA
*CR
5000 — A0129 Mitochondrial DNA
Damage Increases with Age-related Macular
Degeneration in the RPE but not Neural
Retina. Marcia R. Terluk 1 , L. M. Soukup 2 , S. R.
Montezuma 1 , D. A. Ferrington 1 . 1 Ophthalmology
and Visual Neurosciences, University of Minnesota,
Minneapolis, MN; 2 Biology, University of St.
Thomas, St. Paul, MN
5001 — A0130 Oxidative Stress-Induced
Necrosis in RPE Cells. Jakub Hanus 1 , W. C.
Anderson 1 , P. Jin 3 , Q. Liu 4 , S. Wang 1, 2 . 1 Cell
and Molecular Biology, Tulane University, New
Orleans, LA; 2 Ophthalmology, Tulane University,
New Orleans, LA; 3 Human Genetics, Emory
University, Atlanta, GA; 4 Biochemistry, University
of Texas Southwestern Medical Center, Dallas, TX
*CR
5002 — A0131 Phosphorylation Networks in
Age-Related Macular Degeneration. Srinivas R.
Sripathi 1 , O. Sylvester 2 , T. Moser 1 , P. S. Bernstein 3 ,
F. Lamoke 4 , M. Bartoli 4 , W. Jahng 2 . 1 Biological
Sciences, Michigan Tech University, Houghton,
MI; 2 Retina Proteomics Laboratory, Petroleum
Chemistry, American University of Nigeria, Yola,
Nigeria; 3 Ophthalmology and Visual Sciences,
Moran Eye Center, University of Utah, Salt Lake
City, UT; 4 Ophthalmology, Georgia Health Sciences
University, Augusta, GA *CR
5003 — A0132 Evaluation of RPE cell
senescence as a mechanism for age-related
macular degeneration (AMD),. Michael R.
Kozlowski. Arizona College of Optometry,
Midwestern University, Glendale, AZ
5004 — A0133 An In-Vitro Study of the Effect
of Ultraviolet Radiation on Growth Patterns and
Gene Expression of Human ARPE-19 Cybrid H
and J, and their Implications with Age-related
Macular Degeneration (AMD). Deepika Malik 1 ,
P. Falatoonzadeh 1 , T. Hsu 1, 2 , C. A. Ramirez 1 , J.
Cáceres del Carpio 1 , M. Mohamed Moustafa 1 , S.
Jazwinski 3 , M. V. Michael 3 , C. M. Kenney 1 , B. D.
Kuppermann 1 . 1 Ophthalmology, Gavin Herbert
Eye Institute, Irvine, CA; 2 Warren Alpert Medical
School, Brown University, Providence, RI; 3 Tulane
Center for Aging, Tulane University, New Orleans,
LA *CR
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index.
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