Wednesday - ARVO

4733 – 4754 – Wednesday – Posters
Wednesday Posters
11:00 am – 12:45 pm
4733 — C0116 Identification by whole-exome
next-generation sequencing of coding region
mutations as candidates for posterior amorphous
corneal dystrophy. Jonathan Han, R. F. Frausto,
M. J. Kim, A. J. Aldave. Doris Stein, Cornea
Division, Jules Stein Eye Institute, Los Angeles,
CA *CR
4734 — C0117 Lattice corneal dystrophy,
type 1 (LCD1): an epithelial or stromal entity ?
Walter Lisch 1 , B. Seitz 2 . 1 Ophthalmology, Johannes
Gutenberg University Mainz, Mainz, Germany;
2
Ophthalmology, Saarland University, Homburg/
Saar, Germany
4735 — C0118 Proteolytic processing in lattice
corneal dystrophy. Ebbe Toftgaard Poulsen 1 , K.
Runager 1 , M. W. Risør 1 , I. Thøgersen 1 , T. Dyrlund 1 ,
L. R. Thomsen 1 , G. K. Klintworth 2 , J. J. Enghild 1 .
1
Department of Molecular Biology, Aarhus
University, Aarhus C, Denmark; 2 Departments of
Pathology and Ophthalmology, Duke University,
Durham, NC
4736 — C0119 Benzalkonium chloride
accelerates amyloid fibril formation in corneal
dystrophies in vitro. Yuichi Kaji 1, 2 , H. Yagi 2 ,
Y. Kato 2 , Y. Goto 2 , T. Oshika 1 . 1 Ophthalmology,
University of Tsukuba, Ibaraki, Japan; 2 Laboratory
of Protein Folding, Institute for Protein Research
Osaka University, Osaka, Japan
4737 — C0120 Exploring the mechanism
underlying the protein aggregation in stromal
corneal dystrophies caused by amyloidogenic
and non-amyloidogenic mutants of TGFBIp.
Elavazhagan Murugan 1 , R. Lakshminarayanan 1 , R.
W. Beuerman 1, 2 , S. S. Chaurasia 1 , J. S. Mehta 1, 2 .
1
Tissue engineering and stem cell research group,
Singapore Eye Research Institute, Singapore,
Singapore; 2 Singapore National Eye Centre,
Singapore National Eye Centre, Singapore,
Singapore *CR
4738 — C0121 Insights into the molecular
mechanisms of TGFBIp aggregation in corneal
dystrophies. Kasper Runager 1, 2 , J. Underhaug 1 , C.
S. Sørensen 1, 2 , H. Karring 3 , G. K. Klintworth 4 , N.
C. Nielsen 1 , J. J. Enghild 2, 1 . 1 Center for Insoluble
Protein Structures, Aarhus University, Aarhus,
Denmark; 2 Department of Molecular Biology and
Genetics, Aarhus University, Aarhus, Denmark;
3
Institute of Chemical Engineering, University
of Southern Denmark, Odense M, Denmark;
4
Departments of Pathology and Ophthalmology,
Duke University Medical Center, Durham, NC
4739 — C0122 An inducible transgenic
mouse model of TGFBI-related corneal stromal
dystrophy. Andrew J. Huang 1 , C. Liu 2 , Y. Zhang 2 ,
H. Liu 2 . 1 Ophthalmology & Visual Sciences,
Washington Univ School of Med, St Louis,
MO; 2 Ophthalmology, University of Cincinnati,
Cincinnati, OH
4740 — C0123 Identification of TGFBI gene
mutations in Polish patients with corneal
dystrophies. Monika Udziela 1 , M. Oldak 2, 1 , J.
P. Szaflik 1 , A. Federowicz 2 , R. B. Maksym 2 , R.
Ploski 3 , J. Szaflik 1 . 1 Department of Ophthalmology,
Medical University of Warsaw, Warsaw, Poland;
2
Department of Histology and Embryology,
Medical University of Warsaw, Warsaw, Poland;
3
Department of Medical Genetics, Medical
University of Warsaw, Warsaw, Poland
4741 — C0124 The degree of exacerbated
interfacial opacity after LASIK in Granular
Corneal Dystrophy type 2 is related with the
width of area of granular deposits made before
procedure. Eung Kweon Kim, T. Rim, H. Kim,
T. Kim. Ophthalmology, Yonsei Univ College of
Medicine, Seoul, Republic of Korea
4742 — C0125 shRNA Gene-silencing Therapy
for Congenital Stromal Corneal Dystrophy. Rajiv
R. Mohan, A. Sharma, J. T. Rodier, A. Tandon, D. E.
Birk. Mason Eye Institute, University of Missouri-
Columbia, Columbia, MO
Exhibit Hall D0127-D0181
Wednesday, May 08, 2013 11:00 AM-12:45 PM
Glaucoma
442 Surgery and Wound Healing
Moderator: Tina Wong
4743 — D0127 Prospective evaluation of
medical therapy to prevent the hypertensive
phase following implantation of a glaucoma
drainage device. Helen L. Kornmann, A. Kwong, J.
A. Giaconi, J. Caprioli, S. K. Law. Ophthalmology,
Jules Stein Eye Institute, Los Angeles, CA *CR, f
4744 — D0128 High Intensity Focused
Ultrasound (HIFU) in patients with Refractory
Glaucoma. Shlomo Melamed, M. Goldenfeld, D.
Cotlear, A. Skaat. Goldschleger Eye Institute, Sheba
Medical Center, Ramat Gan, Israel *CR, f
4745 — D0129 Ahmed Glaucoma Valve versus
Gold Micro Shunt (GMS) implants - Five years
Results of a Prospective Randomized Clinical
Trial. Iris Moroz, S. Melamed, O. Sagiv, G. J. Ben
Simon, M. Goldenfeld, A. Skaat. Goldschleger Eye
Institute, Tel Hashomer, Israel *CR, f
4746 — D0130 Graft-free Ahmed valve
implantation through a 6mm scleral tunnel.
Kailun Jiang 1 , G. Gdih 2 . 1 The Ottawa Hospital,
Ottawa, ON, Canada; 2 University of Manitoba,
Winnipeg, MB, Canada
4747 — D0131 The PLGA implant as an
antimitotic delivery system after experimental
trabeculectomy. Ignacio Rodriguez-Agirretxe 1, 2 ,
S. Vega 3 , E. Vecino 4 , J. Mendicute 2 , F. Eder 2 , T.
M. Suarez-Cortes 3 , A. Acera 3 . 1 Glaucoma, ICQO,
Bilbao, Spain; 2 Glaucoma, Donostia Hospital,
San Sebastian, Spain; 3 Bioftalmik SL, Derio,
Spain; 4 Cellular Biology, University of the Basque
Country, Leioa, Spain *CR
4748 — D0132 Corneal Endothelial Cells
Loss After Trabeculectomy For Glaucoma.
Juan A. Dios 1, 2 , M. E. Delgado 2 , V. V. Castro 3 .
1
Ophthalmology, Clinica Ricardo Palma, Lima,
Peru; 2 Ophthalmology, Hospital Alberto Sabogal
Sologuren, Callao, Peru; 3 Ophthalmology, Hospital
Nacional Arzobispo Loayza, Lima, Peru
4749 — D0133 Comparison of surgical
outcomes between 360 degree catheter assisted
and traditional 180 degree trabeculotomy in
patients with congenital glaucoma. Monisha
Mandalaywala Vora 1, 3 , C. H. Marcus 1, 2 , R.
F. Rothman 1, 2 , D. D. Hayes 1, 2 , A. Angelilli 1, 2 .
1
Ophthalmology, North Shore Long Island Jewish
Medical Center, Great Neck, NY; 2 Glaucoma
Consultants of Long Island, Lake Success, NY;
3
Hofstra School of Medicine, Lake Success, NY
4750 — D0134 Long term Intraocular
Pressure Control Using Combined Endoscopic
Cyclophotocoagulation (ECP) And
Phacoemulsification in the Treatment of Mild to
Moderate Glaucoma - 5 Year Results. Michael
J. Siegel 1 , W. Boling 5 , O. S. Faridi 6 , C. K. Gupta 3 ,
M. S. Juzych 1, 2 , M. Citron 3, 4 , M. J. Siegel 3, 4 ,
L. I. Siegel 3, 4 . 1 Ophthalmology, Kresge Eye
Institute, Detroit, MI; 2 School of Medicine, Wayne
State University, Detroit, MI; 3 Ophthalmology,
WIlliam Beaumont Hospital, Royal Oak, MI;
4
Ophthalmology, Glaucoma Center of Michigan,
Southfield, MI; 5 Internal Medicine, Detroit
Medical Center, Detroit, MI; 6 Ophthalmology, Eye
Physicians & Surgeons, PC of Connecticut, Milford,
CT
4751 — D0135 Longitudinal Study of Corneal
Endothelial Damage After Anterior Tube Shunt
Surgery. Koichi Ono 1 , T. Hamanaka 2 , S. Kimura 1 .
1
Department of Ophthalmology, Juntendo Tokyo
Koto Geriatric Medical Center, Juntendo University
School of Medicine, Koto-ku, Japan; 2 Department
of Ophthalmology, Japanese Red Cross Medical
Center, Shibuya-ku, Japan
4752 — D0136 Outcomes of combined
glaucoma tube shunt and fluocinolone acetonide
implant placement in uveitic patients compared
to outcomes in uveitic and open angle glaucoma
patients with glaucoma tube shunt placement
alone. Daniel B. Moore, S. Asrani. Ophthalmology,
Duke Eye Center, Durham, NC
4753 — D0137 The effect of aqueous
humour protein content and viscosity on
equilibrium pressure under the scleral flap in
trabeculectomies. Amir Samsudin 1, 2 , I. Eames 3 , S.
Brocchini 2, 4 , P. T. Khaw 2 . 1 University of Malaya,
Kuala Lumpur, Malaysia; 2 NIHR Biomedical
Research Centre at Moorfields Eye Hospital
NHS Foundation Trust and UCL Institute of
Ophthalmology, London, United Kingdom; 3 UCL
Department of Mechanical Engineering, London,
United Kingdom; 4 UCL School of Pharmacy,
London, United Kingdom *CR
4754 — D0138 Outcomes of Pars Plana
Baerveldt Glaucoma Drainage Implant in Boston
Type 1 Keratoprosthesis Surgery. Eun S. Huh, A.
A. Aref, T. S. Vajaranant, J. De la Cruz, F. Y. Chau,
M. S. Cortina. Ophthalmology, Univ of Illinois Eye
& Ear Infirm, Chicago, IL *CR
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index.
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