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4687 – 4709 – Wednesday – Posters Wednesday Posters 11:00 am – 12:45 pm 4687 — B0256 A synthetic carrier for cultured corneal endothelium implantation. Mark Daniell 1 , K. D. Brown 1 , B. Ozcelik 4 , P. McKelvie 3 , H. Zhang 1 , K. Abberton 2 . 1 CERA, Melbourne, VIC, Australia; 2 The O’Brien Institute, Fitzroy, VIC, Australia; 3 Anatomical Pathology, St. Vincent’s Hospital, Melborne, VIC, Australia; 4 Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, VIC, Australia 4688 — B0257 Vision Restoration in Mouse Models of RP using Light-Gated G-Protein Coupled Receptors. Benjamin Gaub, M. Berry, J. Levitz, J. G. Flannery, E. Isacoff. UC Berkeley, Berkeley, CA 4689 — B0258 Connective Tissue Growth Factor Protein Expression by Müller Cells is Bipartite as a Function of Substrate Stiffness. William J. Foster 1, 2 , J. T. Davis 2 . 1 Ophthalmology, Weill-Cornell Med Coll, Houston, TX; 2 Physics, The University of Houston, Houston, TX 4690 — B0259 Corneal Stromal Bioequivalents Secreted on Patterned Silk Substrata by Corneal Fibroblasts and Stem Cells. Jian Wu 1, 2 , Y. Du 3 , J. Rnjak-Kovacina 4 , D. Kaplan 4 , J. L. Funderburgh 3 . 1 McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA; 2 Ophthalmology & Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; 3 Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA; 4 Biomedical Engineering, Tufts University, Medford, MA 4691 — B0260 Kinetics of apoptotic death and oxidative damage in the retina of P23H-1 rats and the protective effects of nanoceria. Lily L. Wong 1 , S. Seal 3, 4 , J. F. McGinnis 1, 2 . 1 Ophthalmology, University of Oklahoma Health Sciences Center & Dean McGee Eye Institute, Oklahoma City, OK; 2 Cell Biology and Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City, OK; 3 Advanced Materials Processing Analysis Center, University of Central Florida, Orlando, FL; 4 Mechanical Materials Aerospace Engineering, Nanoscience & Technology Center, University of Central Florida, Orlando, FL *CR 4692 — B0261 Conversion of human amniotic mesenchymal cells to retinal neural-like cells in conditional medium. Yanqing Zhang 1 , H. Wang 2 , J. Qian 3 . 1 Eye and ENT Hospital of Fudan University, Shanghai, China; 2 Shanghai Xi Mei Aesthetic and Plastic Center, Shanghai, China; 3 Eye and ENT Hospital of Fudan University, Shanghai, China 4693 — B0262 Regulation of Krüppel-like Transcription Factor (KLF’s) Family Members Promotes Potent Axon Regeneration in the Adult Rat Optic Nerve. Yan Wang 1 , A. Apara 1 , M. Blackmore 2 , D. P. Brown 1 , M. E. LeBlanc 3 , A. E. Trillo 1 , J. L. Goldberg 1 . 1 Ophthalmology, Bascom Palmer Eye Institute, Miami, FL; 2 Biomedical Science, College of health science,Marquette University, Milwaukee, WI; 3 PIBS, University of Miami, Miami, FL 4694 — B0263 Positive charged nanoemulsion enhanced cyclosporine penetrate into cornea after ocular topical application. Junjie Zhang, L. Wang, T. Zhou, J. He, H. Xia, H. Zhang. Dpt of Pharmaceutical Science, Henan Eye Institute, Henan Eye Hospital, Zhengzhou, China 4695 — B0264 Induction of cytokeratin 3 expression in immortalized human oral mucosal epithelial cells by the transduction of Pax6. Yuzuru Sasamoto, R. Hayashi, M. Tsujikawa, K. Nishida. Ophthalomology, Osaka University Medical School, Suita, Japan *CR 4696 — B0265 Transplantation of human retinal progenitor cells into the subretinal space of mini pigs. Caihui Jiang, X. Wang, M. Zhang. Ophthal-Schepens Eye Rsrch Inst, Chinese PLA General Hospital, Beijing, China 4697 — B0266 Controlled Physical Properties of Stem Cell Scaffolds for Photoreceptor Regeneration. Kristan Worthington 1, 3 , A. K. Salem 2 , A. Guymon 1 , B. A. Tucker 3 . 1 Chemical and Biochemical Engineering, University of Iowa, Iowa City, IA; 2 Pharmaceutical Science and Translational Therapeutics, University of Iowa, Iowa City, IA; 3 Institute for Vision Research, University of Iowa, Iowa City, IA 4698 — B0267 Development of a bioengineered 3D-model of human conjunctiva. Isabel Arranz- Valsero 1, 2 , L. Garcia-Posadas 1, 2 , A. Fernández 3 , A. López-García 1, 2 , F. Iglesias 3 , Y. Diebold 1, 2 . 1 Ocular Surface Group, IOBA-University of Valladolid, Valladolid, Spain; 2 Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Valladolid, Spain; 3 Human Tissue Bank, San Francisco Clinic Foundation, León, Spain 4699 — B0268 Hybrid interphotoreceptor matrix - poly(caprolactone) scaffolds for human retinal progenitor cell culture and differentiation. Michael J. Young 1 , A. Michaelson 2 , P. Y. Baranov 1 , R. L. Carrier 2 . 1 Schepens Eye Research Inst, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA; 2 Northeastern University, Boston, MA *CR 4700 — B0269 Differentiation Of Induced Pluripotent Stem Cells-Derived Neural Crest Cells Into Corneal Keratocytes In Vivo. Satoru Yoshida 1 , H. Miyashita 1 , M. Yasuda 1 , E. Inagaki 1 , K. Tsubota 1 , H. Okano 2 , S. Shimmura 1 . 1 Ophthalmology, Keio University School of Medicine, Tokyo, Japan; 2 Physiology, Keio University School of Medicine, Tokyo, Japan *CR 4701 — B0270 Nanoparticle polyethylenimine- BMP7 Transfection Dose, Anti-fibrotic Efficacy and Toxicity for the Rabbit Cornea. Chaitasi Naik 1 , J. T. Rodier 1 , A. Sharma 1 , A. Stallard 1 , A. Tandon 1 , A. Klibanov 2 , R. R. Mohan 1 . 1 University of Missouri - Columbia/Mason Eye Institue, Columbia, MO; 2 Massachusetts Institute of Technology, Cambridge, MA 4702 — B0271 Myopia control in guinea pigs with a biomimetic hyaluronic acidbased hydrogel. Mariana Garcia 1 , A. K. Jha 2 , K. E. Healy 2 , C. F. Wildsoet 1 . 1 Vision Science, University of California, Berkeley, Berkeley, CA; 2 Bioengineering, University of California, Berkeley, Berkeley, CA 4703 — B0272 Development of an Amniotic Membrane-Based Cell Scaffold Using Super Critical CO2 Technology. David O. Zamora 1 , J. L. Wehmeyer 2 , H. H. Wang 1 , R. J. Christy 2 , A. J. Johnson 1 . 1 Ocular Trauma, U.S. Army Institute of Surgical Research, Ft. Sam Houston, TX; 2 Extremity Trauma & Regenerative Medicine, U.S. Army Institute of Surgical Research, Ft. Sam Houston, TX 4704 — B0273 pRNA Nanoparticles for Intraviteal Delivery of siRNA in Mouse Retina. Dung V. Nguyen 1 , S. Caballero 1 , S. W. Matthews 2 , J. W. Verlander 2 , M. E. Boulton 3 , P. Guo 4 , M. B. Grant 1 . 1 Pharmacology & Therapeutics, University of Florida, Gainesville, FL; 2 Medicine, University of Florida, Gainesville, FL; 3 Anatomy and Cell Biology, University of Florida, Gainesville, FL; 4 Pharmaceutical Sciences, University of Kentucky, Lexington, KY *CR Exhibit Hall B0274-B0286 Wednesday, May 08, 2013 11:00 AM-12:45 PM Eye Movements / Strabismus / Amblyopia / Neuro-Ophthalmology 440 Strabismus: Treatment Methods Moderator: Howard S. Ying 4705 — B0274 A comparison of inferior and medial rectus weakening by the faden procedure. Karen E. Grove 1, 2 , D. Morrison 2 . 1 Ophthalmology, Meharry Medical College, Nashville, TN; 2 Ophthalmology, Vanderbilt University, Nashville, TN *CR 4706 — B0275 Infection Following Strabismus Surgery; Why Does it Occur and and How to Prevent it? Donny Suh. Ophthalmology Department, University of Nebraska, West Des Moines, IA 4707 — B0276 The role of eye axial length in planning strabismus surgery. Maria Silvana Galantuomo, M. Fossarello, A. Cuccu, I. Zucca. Ophthalmology, University of Cagliari, Cagliari, Italy 4708 — B0277 A modified transposition technique of the superior and inferior rectus muscles in cases with longstanding sixth nerve palsy to reduce postoperative vertical deviation and torsion. Ahmed Z. Soliman, A. Decanini, E. D. Bothun. Ophthalmology, University of Minnesota, Minneapolis, MN 4709 — B0278 Comparison of Inferior Oblique Myectomy and Anterior Transposition on Horizontal Deviation. Tariq S. Alshehri, H. Park. Wilmer Eye Institute, Baltimore, MD The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index. 304
Wednesday – Posters – 4710 – 4732 4710 — B0279 Combined Resect and Recess of a Single Rectus Muscle for incomitant strabismus: review of 10 patients with emphasis on surgical dosage. Vivek Patel 1 , S. Das 2 . 1 University of Ottawa, Ottawa, ON, Canada; 2 Eye institute, University of Ottawa, Ottawa, ON, Canada 4711 — B0280 Adjustable-suture strabismus surgery: A new, removable, sliding noose. Emily Deschler, K. Irsch, K. Guyton, D. L. Guyton. Division of Pediatric Ophthalmology & Adult StrabismusOphthalmology, The Wilmer Eye Institute, The Johns Hopkins School of Medicine, Baltimore, MD *CR 4712 — B0281 Medial Rectus Pulley Posterior Fixation for Divergence excess Intermittent Exotropia with high AC/A Ratio. Jae Ho Jung 1 , H. Choi 2 , J. Lee 1 , S. Cho 1 , J. E. Lee 2 , I. Byon 2 . 1 Ophthalmology, Pusan Nat’l Univ Yangsan Hospital, Yangsan, Republic of Korea; 2 PNUH, Busan, Republic of Korea 4713 — B0282 Effect of inferior oblique weakening surgery on ocular torsion in congenital superior oblique palsy. Jinho Lee 1 , S. Suh 1, 2 , H. Choung 1, 3 , S. Kim 1, 2 . 1 Department of Ophthalmology, Seounl National University College of Medicine, Seoul, Republic of Korea; 2 Seoul Artificial Eye Center, Seounl National University Hospital Clinical Research Institute, Seoul, Republic of Korea; 3 Department of Ophthalmology, Seoul Municipal Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea 4714 — B0283 Superior oblique paralysis: treatment by the botulinum toxin A compared to surgical treatment. Abdulaziz Aloreany 1 , F. Farguette 1 , R. Bordas 1 , G. Saulnier 1 , H. Dalens 1 , F. Chiambaretta 1 , H. Nezzar 1, 2 . 1 ophthalmology, CHU Clermont Ferrand, Clermont ferrand, France; 2 IGCNC EA 3295, Université d’Auvergne, Clermont Ferrand, France 4715 — B0284 Correction of accommodative factor in patients with residual esotropia after treatment with botulinum toxin for infantile esotropia. Mario I. Torres Garcia, R. A. Martinez, M. Acosta Silva, M. A. Najera Covarrubias, K. Calderon Soto. Estrabismo, Hospital Fundacion Nuestra Señora de la Luz, Distrito Federal, Mexico 4716 — B0285 The Effect of a Temperature- Sensitive Poloxamer/Alginate/CaCl2 Mixture After Strabismus Surgery in a Rabbit Model. Won Yeol Ryu, H. Jung, Y. Kwon, W. C. Park, H. Ahn. Department of Ophthalmology, Dong-A University College of Medicine, Busan, Republic of Korea 4717 — B0286 Can Tropicamide 1% Ophthalmic Solution act as a Potential Adjunct Treatment for Post Concussive Visual and Ocular Motor Symptoms? Lynn D. Greenspan. Foundations of Optometric Medicine, Salus University, Elkins Park, PA Exhibit Hall C0101-C0125 Wednesday, May 08, 2013 11:00 AM-12:45 PM Cornea 441 Corneal Development, Differentiation, Dystrophies, Genetics Moderator: Mario Matthaei 4718 — C0101 Role of Shp2 Protein Phosphatase in Mouse Corneal Epithelium Stratification. Chia-Yang Liu 1 , G. Ng 1 , L. Yeh 2, 1 , H. Liu 1 , Y. Zhang 1 , W. W. Kao 1 . 1 Ophthalmology, Univ of Cincinnati, Cincinnati, OH; 2 Department of Ophthalmology, Chang-Gung Memorial Hospital, Linko, Taiwan 4719 — C0102 The homeodomain transcription factor PITX2 is required to establish correct cell lineages and angiogenic privilege in the developing cornea. Philip J. Gage, A. L. Zacharias, C. Kuang. Ophthal & Vis Science, Univ Michigan- Kellogg Eye Ctr, Ann Arbor, MI 4720 — C0103 Expression patterns of angiogenic factors correlate with vascular patterning of the developing anterior eye. Sam Kwiatkowski, R. P. Munjaal, P. Y. Lwigale. Biochemsitry and Cell Biology, Rice University, Houston, TX 4721 — C0104 Role of Netrin-4 and Laminin β2 and γ3 Chains in Corneal Development and Maintenance. Jeremiah Martino 1, 2 , G. Bachay 1, 2 , M. A. Dattilo 1, 2 , D. R. Lazzaro 1, 2 , W. J. Brunken 1, 2 . 1 Ophthalmology and Cell Biology, SUNY Downstate Medical Ctr, Brooklyn, NY; 2 SUNY Eye Institute, Brooklyn, NY 4722 — C0105 Ocular Manifestations of X-linked Reticulate Pigmentary Disorder. Kruti Dajee, H. D. Cavanagh, N. Hogan, L. A. Baker, A. R. Zinn, V. V. Mootha. Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX *CR 4723 — C0106 Novel CHRLD1 Mutation and Secondary Glaucoma in Patient with X-Linked Megalocornea. Xin Gong, J. T. Whitson, V. V. Mootha. Ophthalmology, UT Southwestern Medical Center, Dallas, TX *CR 4724 — C0107 An intronic TCF4 tri-nucleotide repeat expansion associated with Fuchs Corneal Dystrophy. S. Amer Riazuddin 1 , B. C. Gapsis 1 , N. Katsanis 2 , J. D. Gottsch 1 . 1 The Wilmer Eye Institute, Johns Hopkins Univ Sch of Med, Baltimore, MD; 2 Center for Human Disease Modeling, Duke University Medical Center, Durham, NC 4725 — C0108 An Investigation of Mitochondrial Haplogroups in Fuchs Endothelial Corneal Dystrophy. Yi-Ju Li 1, 2 , M. A. Minear 2 , J. Rimmler 2 , E. Balajonda 3 , M. A. Hauser 2 , R. Allingham 3 , G. K. Klintworth 3, 4 , S. G. Gregory 2 , N. A. Afshari 5, 3 . 1 Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC; 2 Center for Human Genetics, Medicine, Duke University Medical Center, Durham, NC; 3 Duke University Eye Center, Duke University Medical Center, Durham, NC; 4 Pathology, Duke University Medical Center, Durham, NC; 5 Shiley Eye Center, University of California San Diego, San Diego, CA *CR 4726 — C0109 Impaired mitochondrial membrane potential in Fuchs endothelial corneal dystrophy. Cecily E. Hamill 1, 2 , T. Schmedt 1, 2 , Y. Chen 1, 2 , U. V. Jurkunas 1, 2 . 1 Massachusetts Eye and Ear Infirmary, Boston, MA; 2 Schepens Eye Research Institute, Boston, MA *CR 4727 — C0110 Abnormal extracellular matrix production in corneal endothelial cells from patients with late-onset Fuchs corneal dystrophy. Julia M. Wessel, M. Zenkel, U. Schlotzer- Schrehardt, B. O. Bachmann, T. Tourtas, F. E. Kruse. Department of Ophthalmology, University of Erlangen-Nuremberg, Erlangen, Germany 4728 — C0111 Three novel mutations in COL8A2 gene of Korean patients with Fuchs’ endothelial corneal dystrophy. Kyu-yeon Hwang 1, 2 , J. Mok 2 , C. Rho 3, 2 , C. Joo 1, 2 . 1 Department of Ophthalmology & Visual Science, Seoul St.Mary`s hospital, the catholic university of Korea, Seoul, Republic of Korea; 2 Catholic Institutes of Visual Science, The Catholic University of Korea, Seoul, Republic of Korea; 3 Department of Ophthalmology & Visual Science, Deajeon St. Mary`s hospital, The Catholic University of Korea, Dae-jeon, Republic of Korea 4729 — C0112 Posterior Polymorphous Corneal Dystrophy 3 Associated with Agenesis of the Corpus Callosum. Michelle Jang, A. N. Roldan, R. F. Frausto, A. J. Aldave. Doris Stein, Cornea Division, Jules Stein Eye Institute, UCLA, Los Angeles, CA *CR 4730 — C0113 Posterior Polymorphous Corneal Dystrophy is Associated with Steep Corneal Curvature. Lydia Ann, R. F. Frausto, F. Yu, C. K. Nguyen, A. J. Aldave. Jules Stein Eye Institute (UCLA), Los Angeles, CA *CR 4731 — C0114 Identification of Genetic Variant Candidates for Posterior Polymorphous Corneal Dystrophy 1 utilizing Next-Generation Sequencing. Ricardo F. Frausto, J. Han, A. J. Aldave. Doris Stein, Cornea Division, Jules Stein Eye Institute, UCLA, Los Angeles, CA *CR 4732 — C0115 Exclusion of Pathogenic Promoter Region Variants and Identification of Novel Nonsense Mutations in ZEB1 in Posterior Polymorphous Corneal Dystrophy. Pejman Bakhtiari, R. F. Frausto, A. N. Roldan, C. Wang, A. J. Aldave. Jules Stein Eye Institue, Los Angeles, CA *CR Wednesday Posters 11:00 am – 12:45 pm f Refer to the Program Number in the Clinical Trial (CT) Registration Index. *CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures. 305
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Wednesday - ARVO

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