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<strong>Wednesday</strong> – Posters – 4619 – 4641<br />
4619 — A0170 A novel Erythropoietin-derived<br />
peptide regulates Endothelial Progenitor Cell<br />
(EPC) mediated retinal vasorepair. Olivia E.<br />
O’Leary 1 , E. Reid 1 , C. M. McVicar 1 , M. Brines 2 , A.<br />
Cerami 2 , R. J. Medina 1 , D. P. Brazil 1 , A. W. Stitt 1 .<br />
1<br />
Centre for Vision and Vascular Science, Queen’s<br />
University Belfast, Belfast, United Kingdom;<br />
2<br />
Warren Pharmaceuticals, Ossining, NY *CR<br />
4620 — A0171 Effect of HMG-CoA reductase<br />
inhibitor(statins) on the expression of catalase<br />
in human retinal pigment epithelial cells. Min<br />
Gu Kang, S. Lee, N. Kim, H. Chin. Department<br />
of Ophthalmology and Inha Vision Science<br />
Laboratory, Inha University School of Medicine,<br />
Incheon, Republic of Korea<br />
4621 — A0172 Resveratrol suppresses the<br />
VEGF expression by inhibition of the CXCR4<br />
Expression in ARPE-19 cells. Inyoung Chung 1 , H.<br />
Seong 2 , S. Kang 2 , J. Park 1 , S. Seo 1 . 1 Ophthalmology,<br />
School of Medicine, Institute of Health Sciences,<br />
Gyeongsang National University, Jinju-si,<br />
Republic of Korea; 2 Anatomy and Neurobiology,<br />
School of Medicine, Institute of Health Sciences,<br />
Medical Research Center for Neural Dysfunction,<br />
Gyeongsang National University, Jinju-si, Republic<br />
of Korea<br />
4622 — A0173 Antiangiogenic Effect of<br />
Quercetin on Laser-Induced Choroidal<br />
Neovascularization in Mice. Junichi Fukuhara 1, 2 ,<br />
K. Noda 1, 2 , S. Takashina 1, 2 , Y. Dong 1, 2 , S.<br />
Kinoshita 1, 2 , Z. Dong 1, 2 , R. Ando 1, 2 , A. Kanda 1, 2 ,<br />
S. Ishida 1, 2 . 1 Laboratory of Ocular Cell Biology<br />
and Visual Science, Hokkaido University Graduate<br />
School of Medicine, Sapporo, Japan; 2 Department<br />
of Ophthalmology, Hokkaido University Graduate<br />
School of Medicine, Sapporo, Japan<br />
4623 — A0174 Genistein Suppresses Laser-<br />
Induced Choroidal Neovascularization in Mice.<br />
Satoshi Kinoshita 1, 2 , K. Noda 1, 2 , S. Takashina 1, 2 ,<br />
Y. Dong 1, 2 , J. Fukuhara 1, 2 , Z. Dong 1, 2 , R. Ando 1, 2 ,<br />
A. Kanda 1, 2 , S. Ishida 1, 2 . 1 Laboratory of Ocular<br />
Cell Biology and Visual Science, Hokkaido<br />
University Graduate School of Medicine, Sapporo,<br />
Japan; 2 Department of Ophthalmology, Hokkaido<br />
University Graduate School of Medicine, Sapporo,<br />
Japan<br />
4624 — A0175 Inhibition of Laser-induced<br />
Choroidal Neovascularization by Macrolactin<br />
Compounds. Sang Jin Kim 1 , J. Kim 1 , D. Kim 2 .<br />
1<br />
Ophthalmology, Samsung Medical Center,<br />
Sungkyunkwan University School of Medicine,<br />
Seoul, Republic of Korea; 2 Research and<br />
Development Center, Daewoo Pharm. Co. Ltd.,<br />
Busan, Republic of Korea *CR<br />
4625 — A0176 Inhibition of choroidal<br />
neovascularization by neutralizing PDGF with<br />
a recombinant fusion protein of PDGFR β<br />
domain. Yiwen Li 1 , W. Tao 2 , V. Ling 2 , A. Nystuen 2 ,<br />
S. A. Elliott 2 , P. Stabila 2 , R. Wen 1 . 1 Bascom Palmer<br />
Eye Institute, University of Miami, Miami, FL;<br />
2<br />
Neurotech USA, Lincoln, RI *CR<br />
4626 — A0177 One-year Results of Intravitreal<br />
Ranibizumab Combined with Reduced-Fluence<br />
Photodynamic Therapy for Polypoidal Choroidal<br />
Vasculopathy. Daisuke Yamanouchi, M. Sakurai,<br />
T. Baba, M. Kitahashi, H. Yokouchi, M. Kubota-<br />
Taniai, S. Yamamoto. Chiba univercity, Chiba, Japan<br />
4627 — A0178 NIPAAm Based Cell Delivery<br />
Scaffolds for Posterior Segment Therapeutics.<br />
Ben Muirhead 1 , S. D. Fitzpatrick 1 , K. Gregory-<br />
Evans 2 , M. Bhatia 1 , H. Sheardown 1 . 1 Biomedical<br />
Engineering, McMaster University, Elmira, ON,<br />
Canada; 2 Ophthalmology and Visual Sciences,<br />
University of British Columbia, Vancouver, BC,<br />
Canada *CR<br />
Exhibit Hall B0092-B0137<br />
<strong>Wednesday</strong>, May 08, 2013 11:00 AM-12:45 PM<br />
Physiology/Pharmacology / Retinal Cell Biology<br />
438 Retinal Flow and VEGF<br />
Moderators: Michele Reibaldi and Tonia S. Rex<br />
4628 — B0092 Subfoveal Choroidal blood<br />
flow in senescence. John V. Lovasik, H. Kergoat,<br />
M. Parent. School of Optometry, University of<br />
Montreal, Montreal, QC, Canada<br />
4629 — B0093 Time-dependent intracellular<br />
pattern of Bevacizumab in RPE cells. Shereen<br />
Hassan M. Aboul Naga 1, 2 , M. Dithmer 1 , J. Roider 1 ,<br />
A. K. Klettner 1 . 1 Ophthalmology, University of<br />
Kiel, University Medical Centre, Kiel, Germany;<br />
2<br />
Ophthalmology, Kasr Al Aini, Cairo University<br />
Hospitals, Cairo, Egypt *CR<br />
4630 — B0094 Antagonism of PDGFRβ<br />
Inhibits Pericyte Recruitment in a Mouse Model<br />
of Corneal Neovascularization. Amy Jensen 1 , R.<br />
Cepeda 1 , M. Maker 1 , C. E. Bigelow 1 , J. Ghosh 1 ,<br />
G. Li 1 , P. A. D’Amore 2 , G. Spohn 1 , B. D. Jaffee 1 , S.<br />
Azarian 1 . 1 Ophthalmology, Novartis, Cambridge,<br />
MA; 2 Ophthalmology, Schepens Eye Research<br />
Institute, Boston, MA *CR<br />
4631 — B0095 Dynamic retinal venous<br />
oscillations are changed in diabetes mellitus<br />
type 1. Konstantin E. Kotliar 1, 2 , I. M. Lanzl 2 , T.<br />
Siegmund 4 , A. Schmidt-Trucksaess 5, 3 . 1 Biomedical<br />
Engineering, Aachen University of Applied<br />
Sciences, Juelich, Germany; 2 Ophthalmology,<br />
Munich University of Technology, Munich,<br />
Germany; 3 Preventive Sports Medicine, Munich<br />
University of Technology, Munich, Germany;<br />
4<br />
Endocrinology and Diabetes, Bogenhausen<br />
Hospital, Munich, Germany; 5 Division of Sports<br />
Medicine, University of Basel, Basel, Switzerland<br />
*CR<br />
4632 — B0096 Parameters related to Choroidal<br />
thickness. Yasuki Ito 1 , K. Oiwa 1 , E. Iwata 1 , A.<br />
Takahashi 1 , T. Yasuma 1 , K. Kawano 1 , N. Hamajima 2 ,<br />
H. Terasaki 1 . 1 Ophthalmology, Nagoya University<br />
Graduate School of Medicine, Nagoya, Japan;<br />
2<br />
Department of Preventive Medicine, Nagoya<br />
University Graduate School of Medicine, Nagoya,<br />
Japan<br />
4633 — B0097 Blockade of PGF/VEGFR1<br />
signaling significantly prevents BRB breakdown,<br />
apoptosis and inflammation in diabetic<br />
retinopathy. Hu Huang, D. Johnson, D. Kim, G. A.<br />
Lutty. Ophthalmology, Johns Hopkins Wilmer Eye<br />
Inst, Baltimore, MD<br />
f Refer to the Program Number in the Clinical Trial (CT) Registration Index. *CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.<br />
301<br />
4634 — B0098 Computational Model of<br />
Oxygen Transport in Retina and Optic Nerve.<br />
David Bragason 1 , E. Stefánsson 1, 2 . 1 Ophthalmology,<br />
Landspitali University Hospital, Reykjavik, Iceland;<br />
2<br />
Medicine, University of Iceland, Reykjavik,<br />
Iceland *CR<br />
4635 — B0099 Increased Retinal Vascular<br />
Tortuosity in Obstructive Sleep Apnea. Amir<br />
Mohsenin 1 , V. Mohsenin 2 , R. A. Adelman 1 .<br />
1<br />
Department of Ophthalmology, Yale University<br />
School of Med, New Haven, CT; 2 Yale Center<br />
for Sleep Medicine, Yale University School of<br />
Medicine, New Haven, CT<br />
4636 — B0100 Oxygen saturation in<br />
retinal hemorrhages. Olafur Palsson 1, 2 , S. H.<br />
Hardarson 1, 2 , T. S. Eliasdottir 2 , E. Stefánsson 1, 2 .<br />
1<br />
Department of Ophthalmology, Landspítali<br />
University Hospital, Reykjavik, Iceland; 2 University<br />
of Iceland, Reykjavik, Iceland *CR<br />
4637 — B0101 Assessment of Total Retinal<br />
Blood Flow under Systemic Hypercapnia<br />
and Hypocapnia. Ayda M. Shahidi 1 , S. R.<br />
Patel 1 , J. G. Flanagan 1, 3 , O. Tan 2 , D. Huang 2 , C.<br />
Hudson 1, 3 . 1 Ophthalmology & Vision Science,<br />
University Health Network, Toronto, ON, Canada;<br />
2<br />
Ophthalmology, Oregon Health and Science<br />
University, Portland, OR; 3 Optometry & Vision<br />
Science, University of Waterloo, Waterloo, ON,<br />
Canada *CR<br />
4638 — B0102 One-year results of<br />
Central Retinal Sensitivity in eyes treated<br />
with Pegaptanib for Proliferative Diabetic<br />
Retinopathy with extended dosing. Blanca C.<br />
Flores, V. H. Gonzalez, R. Diaz-Rohena. Valley<br />
Retina Institute, McAllen, TX *CR, f<br />
4639 — B0103 Persistent hyaloid vessels<br />
counteract insufficient retinal perfusion in the<br />
mouse eye. Christina Seide, M. Garcia Garrido,<br />
V. Sothilingam, N. Tanimoto, S. C. Beck, M. W.<br />
Seeliger. Div of Ocular Neurodegeneration, Ctr for<br />
Ophthal Inst for Ophth Rsrch, Tuebingen, Germany<br />
4640 — B0104 Retinal Vessel Diameter at<br />
High Altitude. Gabriel Willmann 1 , A. Schatz 1 , M.<br />
Fischer 1, 3 , K. Schommer 2 , E. Zrenner 1 , K. Bartz-<br />
Schmidt 1 , F. Gekeler 1 . 1 Centre for Ophthalmology,<br />
University of Tübingen, Tübingen, Germany;<br />
2<br />
Department of Sports Medicine, University<br />
Hospital Heidelberg, Heidelberg, Germany;<br />
3<br />
Nuffield Laboratory of Ophthalmology, University<br />
of Oxford, Oxford, United Kingdom *CR<br />
4641 — B0105 Retinal and Cerebral<br />
Oxygenation Response to Graded Hypoxia.<br />
Sunni R. Patel 1 , C. Hudson 2, 3 , A. M. Shahidi 1 ,<br />
S. Kulasekara 2 , J. Fisher 4 , J. G. Flanagan 2, 3 , W.<br />
Mutch 5 . 1 Ophthalmology and Vision Sciences,<br />
Toronto Western Hospital, Toronto, ON, Canada;<br />
2<br />
Department of Ophthalmology and Vision<br />
Science, University of Toronto, Toronto, ON,<br />
Canada; 3 School of Optometry and Vision Science,<br />
University of Waterloo, Toronto, ON, Canada;<br />
4<br />
School of Physiology, University of Toronto,<br />
Toronto, ON, Canada; 5 Perioperative Medicine<br />
and Anaesthesiology, University of Manitoba,<br />
Winnepeg, MB, Canada *CR<br />
<strong>Wednesday</strong> Posters<br />
11:00 am – 12:45 pm