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<strong>Wednesday</strong> – Posters – 4619 – 4641<br />

4619 — A0170 A novel Erythropoietin-derived<br />

peptide regulates Endothelial Progenitor Cell<br />

(EPC) mediated retinal vasorepair. Olivia E.<br />

O’Leary 1 , E. Reid 1 , C. M. McVicar 1 , M. Brines 2 , A.<br />

Cerami 2 , R. J. Medina 1 , D. P. Brazil 1 , A. W. Stitt 1 .<br />

1<br />

Centre for Vision and Vascular Science, Queen’s<br />

University Belfast, Belfast, United Kingdom;<br />

2<br />

Warren Pharmaceuticals, Ossining, NY *CR<br />

4620 — A0171 Effect of HMG-CoA reductase<br />

inhibitor(statins) on the expression of catalase<br />

in human retinal pigment epithelial cells. Min<br />

Gu Kang, S. Lee, N. Kim, H. Chin. Department<br />

of Ophthalmology and Inha Vision Science<br />

Laboratory, Inha University School of Medicine,<br />

Incheon, Republic of Korea<br />

4621 — A0172 Resveratrol suppresses the<br />

VEGF expression by inhibition of the CXCR4<br />

Expression in ARPE-19 cells. Inyoung Chung 1 , H.<br />

Seong 2 , S. Kang 2 , J. Park 1 , S. Seo 1 . 1 Ophthalmology,<br />

School of Medicine, Institute of Health Sciences,<br />

Gyeongsang National University, Jinju-si,<br />

Republic of Korea; 2 Anatomy and Neurobiology,<br />

School of Medicine, Institute of Health Sciences,<br />

Medical Research Center for Neural Dysfunction,<br />

Gyeongsang National University, Jinju-si, Republic<br />

of Korea<br />

4622 — A0173 Antiangiogenic Effect of<br />

Quercetin on Laser-Induced Choroidal<br />

Neovascularization in Mice. Junichi Fukuhara 1, 2 ,<br />

K. Noda 1, 2 , S. Takashina 1, 2 , Y. Dong 1, 2 , S.<br />

Kinoshita 1, 2 , Z. Dong 1, 2 , R. Ando 1, 2 , A. Kanda 1, 2 ,<br />

S. Ishida 1, 2 . 1 Laboratory of Ocular Cell Biology<br />

and Visual Science, Hokkaido University Graduate<br />

School of Medicine, Sapporo, Japan; 2 Department<br />

of Ophthalmology, Hokkaido University Graduate<br />

School of Medicine, Sapporo, Japan<br />

4623 — A0174 Genistein Suppresses Laser-<br />

Induced Choroidal Neovascularization in Mice.<br />

Satoshi Kinoshita 1, 2 , K. Noda 1, 2 , S. Takashina 1, 2 ,<br />

Y. Dong 1, 2 , J. Fukuhara 1, 2 , Z. Dong 1, 2 , R. Ando 1, 2 ,<br />

A. Kanda 1, 2 , S. Ishida 1, 2 . 1 Laboratory of Ocular<br />

Cell Biology and Visual Science, Hokkaido<br />

University Graduate School of Medicine, Sapporo,<br />

Japan; 2 Department of Ophthalmology, Hokkaido<br />

University Graduate School of Medicine, Sapporo,<br />

Japan<br />

4624 — A0175 Inhibition of Laser-induced<br />

Choroidal Neovascularization by Macrolactin<br />

Compounds. Sang Jin Kim 1 , J. Kim 1 , D. Kim 2 .<br />

1<br />

Ophthalmology, Samsung Medical Center,<br />

Sungkyunkwan University School of Medicine,<br />

Seoul, Republic of Korea; 2 Research and<br />

Development Center, Daewoo Pharm. Co. Ltd.,<br />

Busan, Republic of Korea *CR<br />

4625 — A0176 Inhibition of choroidal<br />

neovascularization by neutralizing PDGF with<br />

a recombinant fusion protein of PDGFR β<br />

domain. Yiwen Li 1 , W. Tao 2 , V. Ling 2 , A. Nystuen 2 ,<br />

S. A. Elliott 2 , P. Stabila 2 , R. Wen 1 . 1 Bascom Palmer<br />

Eye Institute, University of Miami, Miami, FL;<br />

2<br />

Neurotech USA, Lincoln, RI *CR<br />

4626 — A0177 One-year Results of Intravitreal<br />

Ranibizumab Combined with Reduced-Fluence<br />

Photodynamic Therapy for Polypoidal Choroidal<br />

Vasculopathy. Daisuke Yamanouchi, M. Sakurai,<br />

T. Baba, M. Kitahashi, H. Yokouchi, M. Kubota-<br />

Taniai, S. Yamamoto. Chiba univercity, Chiba, Japan<br />

4627 — A0178 NIPAAm Based Cell Delivery<br />

Scaffolds for Posterior Segment Therapeutics.<br />

Ben Muirhead 1 , S. D. Fitzpatrick 1 , K. Gregory-<br />

Evans 2 , M. Bhatia 1 , H. Sheardown 1 . 1 Biomedical<br />

Engineering, McMaster University, Elmira, ON,<br />

Canada; 2 Ophthalmology and Visual Sciences,<br />

University of British Columbia, Vancouver, BC,<br />

Canada *CR<br />

Exhibit Hall B0092-B0137<br />

<strong>Wednesday</strong>, May 08, 2013 11:00 AM-12:45 PM<br />

Physiology/Pharmacology / Retinal Cell Biology<br />

438 Retinal Flow and VEGF<br />

Moderators: Michele Reibaldi and Tonia S. Rex<br />

4628 — B0092 Subfoveal Choroidal blood<br />

flow in senescence. John V. Lovasik, H. Kergoat,<br />

M. Parent. School of Optometry, University of<br />

Montreal, Montreal, QC, Canada<br />

4629 — B0093 Time-dependent intracellular<br />

pattern of Bevacizumab in RPE cells. Shereen<br />

Hassan M. Aboul Naga 1, 2 , M. Dithmer 1 , J. Roider 1 ,<br />

A. K. Klettner 1 . 1 Ophthalmology, University of<br />

Kiel, University Medical Centre, Kiel, Germany;<br />

2<br />

Ophthalmology, Kasr Al Aini, Cairo University<br />

Hospitals, Cairo, Egypt *CR<br />

4630 — B0094 Antagonism of PDGFRβ<br />

Inhibits Pericyte Recruitment in a Mouse Model<br />

of Corneal Neovascularization. Amy Jensen 1 , R.<br />

Cepeda 1 , M. Maker 1 , C. E. Bigelow 1 , J. Ghosh 1 ,<br />

G. Li 1 , P. A. D’Amore 2 , G. Spohn 1 , B. D. Jaffee 1 , S.<br />

Azarian 1 . 1 Ophthalmology, Novartis, Cambridge,<br />

MA; 2 Ophthalmology, Schepens Eye Research<br />

Institute, Boston, MA *CR<br />

4631 — B0095 Dynamic retinal venous<br />

oscillations are changed in diabetes mellitus<br />

type 1. Konstantin E. Kotliar 1, 2 , I. M. Lanzl 2 , T.<br />

Siegmund 4 , A. Schmidt-Trucksaess 5, 3 . 1 Biomedical<br />

Engineering, Aachen University of Applied<br />

Sciences, Juelich, Germany; 2 Ophthalmology,<br />

Munich University of Technology, Munich,<br />

Germany; 3 Preventive Sports Medicine, Munich<br />

University of Technology, Munich, Germany;<br />

4<br />

Endocrinology and Diabetes, Bogenhausen<br />

Hospital, Munich, Germany; 5 Division of Sports<br />

Medicine, University of Basel, Basel, Switzerland<br />

*CR<br />

4632 — B0096 Parameters related to Choroidal<br />

thickness. Yasuki Ito 1 , K. Oiwa 1 , E. Iwata 1 , A.<br />

Takahashi 1 , T. Yasuma 1 , K. Kawano 1 , N. Hamajima 2 ,<br />

H. Terasaki 1 . 1 Ophthalmology, Nagoya University<br />

Graduate School of Medicine, Nagoya, Japan;<br />

2<br />

Department of Preventive Medicine, Nagoya<br />

University Graduate School of Medicine, Nagoya,<br />

Japan<br />

4633 — B0097 Blockade of PGF/VEGFR1<br />

signaling significantly prevents BRB breakdown,<br />

apoptosis and inflammation in diabetic<br />

retinopathy. Hu Huang, D. Johnson, D. Kim, G. A.<br />

Lutty. Ophthalmology, Johns Hopkins Wilmer Eye<br />

Inst, Baltimore, MD<br />

f Refer to the Program Number in the Clinical Trial (CT) Registration Index. *CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures.<br />

301<br />

4634 — B0098 Computational Model of<br />

Oxygen Transport in Retina and Optic Nerve.<br />

David Bragason 1 , E. Stefánsson 1, 2 . 1 Ophthalmology,<br />

Landspitali University Hospital, Reykjavik, Iceland;<br />

2<br />

Medicine, University of Iceland, Reykjavik,<br />

Iceland *CR<br />

4635 — B0099 Increased Retinal Vascular<br />

Tortuosity in Obstructive Sleep Apnea. Amir<br />

Mohsenin 1 , V. Mohsenin 2 , R. A. Adelman 1 .<br />

1<br />

Department of Ophthalmology, Yale University<br />

School of Med, New Haven, CT; 2 Yale Center<br />

for Sleep Medicine, Yale University School of<br />

Medicine, New Haven, CT<br />

4636 — B0100 Oxygen saturation in<br />

retinal hemorrhages. Olafur Palsson 1, 2 , S. H.<br />

Hardarson 1, 2 , T. S. Eliasdottir 2 , E. Stefánsson 1, 2 .<br />

1<br />

Department of Ophthalmology, Landspítali<br />

University Hospital, Reykjavik, Iceland; 2 University<br />

of Iceland, Reykjavik, Iceland *CR<br />

4637 — B0101 Assessment of Total Retinal<br />

Blood Flow under Systemic Hypercapnia<br />

and Hypocapnia. Ayda M. Shahidi 1 , S. R.<br />

Patel 1 , J. G. Flanagan 1, 3 , O. Tan 2 , D. Huang 2 , C.<br />

Hudson 1, 3 . 1 Ophthalmology & Vision Science,<br />

University Health Network, Toronto, ON, Canada;<br />

2<br />

Ophthalmology, Oregon Health and Science<br />

University, Portland, OR; 3 Optometry & Vision<br />

Science, University of Waterloo, Waterloo, ON,<br />

Canada *CR<br />

4638 — B0102 One-year results of<br />

Central Retinal Sensitivity in eyes treated<br />

with Pegaptanib for Proliferative Diabetic<br />

Retinopathy with extended dosing. Blanca C.<br />

Flores, V. H. Gonzalez, R. Diaz-Rohena. Valley<br />

Retina Institute, McAllen, TX *CR, f<br />

4639 — B0103 Persistent hyaloid vessels<br />

counteract insufficient retinal perfusion in the<br />

mouse eye. Christina Seide, M. Garcia Garrido,<br />

V. Sothilingam, N. Tanimoto, S. C. Beck, M. W.<br />

Seeliger. Div of Ocular Neurodegeneration, Ctr for<br />

Ophthal Inst for Ophth Rsrch, Tuebingen, Germany<br />

4640 — B0104 Retinal Vessel Diameter at<br />

High Altitude. Gabriel Willmann 1 , A. Schatz 1 , M.<br />

Fischer 1, 3 , K. Schommer 2 , E. Zrenner 1 , K. Bartz-<br />

Schmidt 1 , F. Gekeler 1 . 1 Centre for Ophthalmology,<br />

University of Tübingen, Tübingen, Germany;<br />

2<br />

Department of Sports Medicine, University<br />

Hospital Heidelberg, Heidelberg, Germany;<br />

3<br />

Nuffield Laboratory of Ophthalmology, University<br />

of Oxford, Oxford, United Kingdom *CR<br />

4641 — B0105 Retinal and Cerebral<br />

Oxygenation Response to Graded Hypoxia.<br />

Sunni R. Patel 1 , C. Hudson 2, 3 , A. M. Shahidi 1 ,<br />

S. Kulasekara 2 , J. Fisher 4 , J. G. Flanagan 2, 3 , W.<br />

Mutch 5 . 1 Ophthalmology and Vision Sciences,<br />

Toronto Western Hospital, Toronto, ON, Canada;<br />

2<br />

Department of Ophthalmology and Vision<br />

Science, University of Toronto, Toronto, ON,<br />

Canada; 3 School of Optometry and Vision Science,<br />

University of Waterloo, Toronto, ON, Canada;<br />

4<br />

School of Physiology, University of Toronto,<br />

Toronto, ON, Canada; 5 Perioperative Medicine<br />

and Anaesthesiology, University of Manitoba,<br />

Winnepeg, MB, Canada *CR<br />

<strong>Wednesday</strong> Posters<br />

11:00 am – 12:45 pm

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