Wednesday - ARVO

4170 – 4188 – Wednesday – Posters
Wednesday Posters
8:30 am – 10:15 am
4170 — A0088 Reticular pseudodrusen and
their topographic relation to choroidal watershed
zones and localized changes in choroidal volume
and choroidal thickness. Florian Alten, C. R.
Clemens, N. Eter. University Eye Hosp Muenster,
Muenster, Germany *CR
4171 — A0089 Long-term evaluation of
drusen area and volume using polarizationsensitive
OCT. Ferdinand G. Schlanitz 1 , B.
Baumann 2 , M. Bolz 1 , E. Gotzinger 2 , M. Pircher 2 ,
C. K. Hitzenberger 2 , U. Schmidt-Erfurth 1 .
1
Ophthalmology, Medical University of Vienna,
Vienna, Austria; 2 Center for Medical Physics and
Biomedical Engineering, Medical University of
Vienna, Vienna, Austria *CR
4172 — A0090 Longitudinal analysis of
reticular drusen associated with age-related
macular degeneration. Julia S. Steinberg, J.
Auge, M. Fleckenstein, F. G. Holz, S. Schmitz-
Valckenberg. Department of Ophthalmology,
University of Bonn, Bonn, Germany *CR
4173 — A0091 Preferential Hyperacuity
Perimetry Monitoring in Patients During
Treatment of Neovascular Age-related Macular
Degeneration. Merina Thomas 1, 2 , Y. Wolfson 1 , V.
Chaikitmongkol 1, 3 , N. M. Bressler 1 . 1 Department
of Ophthalmology, Retina Division, Wilmer
Eye Institute, Johns Hopkins University School
of Medicine, Baltimore, MD; 2 Department of
Ophthalmology, University of Illinois at Chicago,
Chicago, IL; 3 Department of Ophthalmology,
Chiang Mai University, Chiang Mai, Thailand *CR
4174 — A0092 Visual outcomes of an Inject
and Extend protocol of intravitreal antivascular
endothelial growth factor treatment in
neovascular age-related macular degeneration
over two years. Farshad Abedi, S. Wickramsinghe,
A. Islam, K. M. Inglis, R. H. Guymer.
Ophthalmology, Centre for Eye Research Australia,
University of Melbourne, Royal Victorian Eye and
Ear Hospital, East Melbourne, VIC, Australia *CR
4175 — A0093 Prospective Randomized
Controlled Trial of Combination Ranibizumab
and Ketorolac for Wet Age-Related Macular
Degeneration. Andrea Russo 1 , C. Costagliola 2 , L.
Delcassi 1 , M. R. Romano 3 , F. Semeraro 1 . 1 Univ degli
Studi di Brescia - Italy, Brescia, Italy; 2 Università
del Molise, Campobasso, Italy; 3 Istituto Clinico
Humanitas, Milano, Italy *CR
4176 — A0094 Aflibercept Rescue of
Bevacizumab- or Ranibizumab-Resistant
Choroidal Neovascularization in Age-Related
Macular Degeneration. Cheryl A. Arcinue, F. Ma,
G. Barteselli, S. Lee, S. El-Emam, A. L. Doede, M.
Gomez, W. Freeman. Jacobs Retina Center, UCSD
Shiley Eye Center, La Jolla, CA *CR
Exhibit Hall B0170-B0195
Wednesday, May 08, 2013 8:30 AM-10:15 AM
Retinal Cell Biology
415 Retinal and Photoreceptor
Degeneration II: Cell Biology
Moderators: Susan E. Brockerhoff and
Ulrich F. Luhmann
4177 — B0170 Myo/Nog Cells Promote
Photoreceptor Cell Survival in the Stressed
Retina. Arturo Bravo-Nuevo 1 , A. Brandli 2 , J. V.
Gerhart 1 , M. Pitts 1 , J. Stone 2 , M. George-Weinstein 1 .
1
Lankenau Institute for Medical Research,
Wynnewood, PA; 2 Physiology, University of
Sydney, Sydney, NSW, Australia *CR
4178 — B0171 Responsiveness of rhodopsin
kinase GRK1 promoter activity to light. Shahrokh
C. Khani, Z. Oskouie. Ophthalmology, Schepens
Eye Research Inst, Boston, MA
4179 — B0172 Early indications of pending
degeneration in a mouse model of photoreceptor
light damage. Emily Levine 1 , R. J. Zawadzki 2 , H.
Cheng 3 , S. I. Simon 4 , E. N. Pugh 1, 5 , M. E. Burns 1, 2 .
1
Cell Biology and Human Anatomy, UC Davis,
Davis, CA; 2 Ophthalmology & Vision Science,
UC Davis, Davis, CA; 3 Neurobiology, Physiology
and Behavior, UC Davis, Davis, CA; 4 Biomedical
Engineering, UC Davis, Davis, CA; 5 Physiology
and Membrane Biology, UC Davis, Davis, CA
4180 — B0173 Constitutive Rhodopsin
Activation rather than Mistrafficking Results in
Photoreceptor Death in the D190N Preclinical
Model of Retinitis Pigmentosa. Javier Sancho-
Pelluz 1, 2 , W. Lee 1 , Y. Tsai 1 , I. Washington 1 , S. H.
Tsang 1, 4 , C. Lin 3, 4 . 1 Department of Ophthalmology,
Columbia University, New York, NY; 2 Department
of Medicine, Catholic University of Valencia,
Valencia, Spain; 3 Herbert Irving Comprehensive
Cancer Center, Columbia University, New York,
NY; 4 Department of Pathology and Cell Biology,
College of Physicians and Surgeons, Columbia
University, New York, NY
4181 — B0174 Insufficient proteasomal activity
is a common stress factor in multiple forms
of inherited retinal degeneration. Ekaterina
Lobanova, S. Finkelstein, N. P. Skiba, V. Y.
Arshavsky. Albert Eye Research Institute, Durham,
NC
4182 — B0175 Decreased Proteasomal Activity
Causes Retinal Degeneration in Mice. Ryo
Ando 1, 2 , K. Noda 1, 2 , U. Tomaru 3 , M. Kamoshita 4 ,
Y. Ozawa 4 , S. Notomi 5 , T. Hisatomi 5 , A. Kanda 1, 2 ,
S. Ishida 1, 2 . 1 Laboratory of Ocular Cell Biology
and Visual Science, Hokkaido University Graduate
School of Medicine, Sapporo, Japan; 2 Department
of Ophthalmology, Hokkaido University
Graduate School of Medicine, Sapporo, Japan;
3
Department of Pathology, Hokkaido University
Graduate School of Medicine, Sapporo, Japan;
4
Department of Ophthalmology, Keio University
School of Medicine, Tokyo, Japan; 5 Department
of Ophthalmology, Graduate School of Medical
Sciences, Kyushu University, Fukuoka, Japan *CR
4183 — B0176 Rod Photoreceptor neuritic
sprouting is responsive to Sema3A. Frank
Kung 1, 2 , A. Axelrod 3 , D. R. Siegel 3 , E. Townes-
Anderson 1 . 1 Biomedical Engineering, UMDNJ,
Newark, NJ; 2 Biomedical Engineering, NJIT,
Newark, NJ; 3 Department of Chemistry and
Biochemistry, The University of Texas at Austin,
Chesapeake, VA
4184 — B0177 Strain Dependence of Myeloid
Cell-Associated Retinal Dysplasia in Crb1 rd8
Mice. Mark P. Krebs, W. Hicks, L. Stone, J.
Naggert, P. M. Nishina. The Jackson Laboratory,
Bar Harbor, ME
4185 — B0178 The genetic background
determines the severity of retinal pathology
in homozygous Crb1 rd8/rd8 mice. Ulrich F.
Luhmann 1 , L. S. Carvalho 1 , J. Cowing 1 , P. M.
Munro 4 , P. Potter 3 , J. W. Bainbridge 1, 2 , R. R.
Ali 1, 2 . 1 Department of Genetics, UCL Institute
of Ophthalmology, London, United Kingdom;
2
NIHR Moorfields Biomedical Research Centre at
Moorfields Eye Hospital NHS Foundation Trust
and UCL Institute of Ophthalmology, London,
United Kingdom; 3 MRC Harwell, Oxfordshire,
United Kingdom; 4 Imaging Unit, UCL Institute of
Ophthalmology, London, United Kingdom *CR
4186 — B0179 Characterization of a Novel
Mouse Mutant with Retinal Degeneration and
Male Infertility. Chun-hong Xia 1 , B. Chang 2 ,
X. Gong 1 . 1 School of Optometry, University of
California, Berkeley, Berkeley, CA; 2 The Jackson
Laboratory, Bar Harbor, ME
4187 — B0180 Electroretinographic and
OCT Retinal Morphologic Characterization
of the Crx Rdy Cat: An Animal Model for Severe
Dominant Retinopathies Associated with CRX
Mutations. Laurence M. Occelli 1 , J. T. Bartoe 1 ,
J. R. Querubin 1 , K. Narfstrom 2 , S. M. Petersen-
Jones 1 . 1 Small Animal Clinical Sciences, Michigan
State University, East Lansing, MI; 2 Dept of Vet
Med & Surgery, University of Missouri-Columbia,
Columbia, MO
4188 — B0181 Comparative analysis of
neurodegenerative markers in ten different
animal models for retinal degeneration
reveals prevalence of non-apoptotic cell death
mechanisms. Blanca Arango-Gonzalez 1 , D.
Trifunović 1 , A. Sahaboglu-Tekgöz 1 , K. Kranz 2 ,
S. Michalakis 3 , P. Farinelli 1, 4 , S. Cottet 5 , P.
A. Ekstrom 4 , M. Ueffing 1 , F. Paquet-Durand 1 .
1
Institute for Ophthalmic Research, Centre for
Ophthalmology, Eberhard Karls-Universität
Tübingen, Tuebingen, Germany; 2 Department of
Neurobiology, University of Oldenburg, Oldenburg,
Germany; 3 Center for Integrated Protein Science
Munich (CIPSM) and Department of Pharmacy,
Center for Drug Research, Ludwig-Maximilians-
Universität München, Munich, Germany; 4 Division
of Ophthalmology, Department of Clinical Sciences,
University of Lund, Lund, Sweden; 5 Institute
for Research in Ophthalmology, University of
Lausanne, Lausanne, Switzerland
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index.
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