Wednesday - ARVO

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4130 – 4149 – Wednesday – Posters Wednesday Posters 8:30 am – 10:15 am Exhibit Hall A0048-A0094 Wednesday, May 08, 2013 8:30 AM-10:15 AM Retina 414 AMD III, RE Moderators: Itay Chowers and Christine A. Curcio 4130 — A0048 Focal Retinal Sensitivity Before and After Selective Retina Therapy for Central Serous Chorioretinopathy. Ayako Yasui 1 , M. Yamamoto 1 , T. Kohno 1 , T. yoneda 1 , Y. Yoshida 1 , H. Iwami 1 , D. Theisen-Kunde 2 , Y. Miura 2, 3 , R. Brinkmann 2 , K. Shiraki 1 . 1 Ophthalmology and Visual Science, Osaka city University, Osaka, Japan; 2 Medical Laser Center Luebeck, Luebeck, Germany; 3 Institute of Biomedical Optics, University of Luebeck, Luebeck, Germany *CR, f 4131 — A0049 Automatic Temperature Controlled Retinal Photocoagulation Facilitates Four Predictable Lesion Strengths Including Sub-threshold Lesions. Stefan O. Koinzer 1 , C. Hesse 1 , A. Baade 2 , K. Schlott 3, 2 , A. Caliebe 4 , M. Saeger 1 , R. Brinkmann 3, 2 , J. Roider 1 . 1 Ophthalmology Campus Kiel, University hospital of Schleswig-Holstein, Kiel, Germany; 2 Medical Laser Center Luebeck GmbH, Luebeck, Germany; 3 Institute of Biomedical Optics, University of Luebeck, Luebeck, Germany; 4 Institute of Medical Informatics and Statistics, University hospital of Schleswig-Holstein, Kiel, Germany *CR 4132 — A0050 Modulation of Transgene Expression in Retinal Gene Therapy by Selective Laser Treatment. Daniel Lavinsky 2, 1 , T. W. Chalberg 3 , Y. Mandel 2 , P. Huie 2 , R. Dalal 2 , M. F. Marmor 2 , D. V. Palanker 2 . 1 Ophthalmology, Federal Univesity of Rio Grande do Sul, Porto Alegre, Brazil; 2 Ophthalmology and HEPL, Stanford University, Stanford, CA; 3 Avalanche Biotechnologies, San Francisco, CA *CR 4133 — A0051 Fluorescein angiography versus superimposed OCT-guided macular laser photocoagulation. Igor Kozak 1, 2 , S. El-Emam 1 , L. Cheng 1 , D. G. Bartsch 1 , J. Chhablani 3 , W. Freeman 1 , N. G. Ghazi 2 , J. Arevalo 2, 4 . 1 Ophthalmology, University of California San Diego, La Jolla, CA; 2 Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 3 Vitreoretina, LV Prasad Eye Institute, Heyderabad, India; 4 Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD *CR 4134 — A0052 Six-month Report of Selective Retina Therapy on Central Serous Chorioretinopathy in Japanese Patients. Manabu Yamamoto 1 , T. Kohno 1 , T. Voneda 1 , Y. Yoshida 1 , H. Iwami 1 , A. Yasui 1 , D. Theisen-Kunde 2 , Y. Miura 3 , R. Brinkmann 3, 2 , K. Shiraki 1 . 1 Ophthalmology & Visual Sciences, Osaka City Univ Grad School of Medicine, Osaka-Shi, Japan; 2 Medical Laser Center Luebeck, Luebeck, Germany; 3 Institute of Biomedical Optics, University of Luebeck, Luebeck, Germany *CR, f 4135 — A0053 Approach to Previously Vitrectomized Patients with Neovascular Age- Related Macular Degeneration with Reduced Response to Anti-vascular Endothelial Growth Factor Treatment. Mohammad Zubair Y. Arain 1 , Q. V. Hoang 1, 2 , J. S. Slakter 2 , S. Chang 1 . 1 Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Medical Center, New York, NY; 2 Vitreous, Retina, Macula Consultants of New York, New York, NY *CR 4136 — A0054 Selective retina treatment (SRT) automatically controlled by a real-time reflectometry in a rabbit model. Young Jung Roh 1 , E. Seifert 2 , T. Dirk 2 , Y. Park 1 , S. Kang 1 , R. Brinkmann 2 . 1 Ophthalmology, St Mary’s Hospital, Seoul, Republic of Korea; 2 Biomedical Optics, University of Lubeck, Lubeck, Germany *CR 4137 — A0055 Effects of repeated subthreshold micropulse laser photocoagulation in rabbit eyes. Dongkyu Lee 1 , H. Kang 1 , S. Lee 2 , Y. You 1 , S. Kim 1 , O. Kwon 1 . 1 Retina center, Nune Eye Hospital, Seoul, Republic of Korea; 2 Ophthalmology, Soonchunhynag University Hospital, Seoul, Republic of Korea 4138 — A0056 Classification of Rabbit Photocoagulation Lesions in Optical Coherence Tomography and Class-related Coagulation Temperatures. Carola Hesse 1 , S. O. Koinzer 1 , A. Baade 2 , K. Schlott 2, 3 , A. Caliebe 4 , M. Saeger 1 , R. Brinkmann 3, 2 , J. Roider 1 . 1 Dept. of Ophthalmology, Campus Kiel, University Hospital of Schleswig- Holstein, Kiel, Germany; 2 Medical Lasercenter Lübeck GmbH, Lübeck, Germany; 3 Institut of Biomedical Optics, University of Lübeck, Lübeck, Germany; 4 Institut of Medical Informatics and Statistics, University Hospital of Schleswig- Holstein, Kiel, Germany *CR 4139 — A0057 Various Laser Treatments for Retinal Capillary Hemangioma. Liqin Gao, F. Zhang. Department of Ophthalmology, Beijing Tongren Hospital, Beijing, China 4140 — A0058 Subthreshold diode micropulse laser photocoagulation versus low-fluence photodynamic therapy for the treatment of chronic central serous chorioretinopathy. Juan Giralt 1 , R. P. Casaroli-Marano 1 , A. Burés- Jelstrup 2 , R. Navarro 2 , J. Martinez-Toldos 3 , C. Fernandez-Martinez 3 , M. Alforja 1 , A. Rey Torrente 1 . 1 Ophthalmology, Hospital Clinic de Barcelona, Barcelona, Spain; 2 IMO, Barcelona, Spain; 3 Hospital General Universitario de Elche, Elche, Spain *CR 4141 — A0059 Early changes on SD-OCT in eyes with cystoid macular edema (CME) after 577 nm subthreshold MicroPulse Laser Treatment (MPLT). Paola Salvetti 1 , L. de Polo 1, 2 , M. Oldani 1, 2 , R. Ruello 1 . 1 Centro Oculistico Bergamasco, Bergamo, Italy; 2 Eye Clinic Department of Biomedical and Clinical Science “Luigi Sacco”, Luigi Sacco Hospital, Milano, Italy 4142 — A0060 Threshold and Subthreshold Retinal Laser Therapy. But which Threshold? Giorgio Dorin. Clinical Application Development, IRIDEX Corp, Mountain View, CA *CR 4143 — A0061 Persistence of Weekly Vision Self-monitoring Behavior in Non-Neovascular Age-Related Macular Degeneration Subjects Randomized to the Vision and Memory Stimulating (VMS) booklet. Mark C. Roser 1 , P. Beaton 1 , S. Torr-Brown 1 , A. Nwanko 2 , G. Dagnelie 2 , A. K. Bittner 2 . 1 Results Group, LLC, Hebron, CT; 2 1Johns Hopkins Wilmer Eye Institute, Baltimore, MD *CR, f 4144 — A0062 Screening for AMD at an University Hospital: Database análisis and considerations. Carmen N. Demetrio, M. Zas. Ophthalmology, Hospital de Clínicas, Buenos Aires, Argentina 4145 — A0063 Zinc supplementation lowers complement overactivation in patients with age-related macular degeneration. B. Jeroen Klevering 1 , D. Smailhodzic 1 , A. I. Den Hollander 1, 2 , J. P. van de Ven 1 , J. M. Groenewoud 3 , S. Fauser 4 , M. R. Daha 5 , G. van der Wilt 3 , C. B. Hoyng 1 . 1 Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 2 Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 3 Department of Epidemiology, Biostatistics, and HTA, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 4 Ophthalmology, University of Cologne, Cologne, Germany; 5 Department of Nephrology, Leiden University Medical Center, Leiden, Netherlands f 4146 — A0064 Novel Laser treatment for Early Age-related Macular Degeneration. Kate Brassington 1 , L. Gurrin 3 , K. Aung 1 , R. H. Guymer 1, 2 . 1 Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, VIC, Australia; 2 Department of Ophthalmology, University of Melbourne, Melbourne, VIC, Australia; 3 Melbourne School of Population Health, University of Melbourne, Melbourne, VIC, Australia *CR, f 4147 — A0065 ex vivo Spectral Domain Optical Coherence Tomography (SD-OCT) of Retina-Choriocapillaris (R-CC) Specimen: Factors influencing Image Quality. Laurenz L. Sonnentag, S. Grisanti, M. Rudolf. Department of Ophthalmology, University of Luebeck, Luebeck, Germany *CR 4148 — A0066 Quantitative Optical Coherence Tomography Analysis Of Change in Pigment Epithelial Detachment Morphology Following Intravitreal Aflibercept Injection In Eyes With Recalcitrant Neovascular Age-Related Macular Degeneration. Mihai Mititelu, D. S. Grewal, D. Sarezky, R. Mirza, M. K. Gill, A. T. Lyon. Ophthalmology, Northwestern University, Feinberg School of Medicine, Chicago, IL 4149 — A0067 Drusen Detection on Multimodal Imaging- Early Markers Observational Study. Rufino Silva 1, 2 , R. E. Hogg 3 , G. Murphy 3 , G. Staurenghi 4 , C. Rosina 4 , A. Santos 2 , U. Chakravarthy 3 . 1 Ophthalmology, Universitary Hospital Coimbra Center, Coimbra, Portugal; 2 CEC, AIBILI, Coimbra, Portugal; 3 Center for Vision and Vascular Science, Queen’s University Belfast, Belfast, Ireland; 4 Dept of Biomedical and Clinical Science (Luigi Sacco), University of Milan, Milan, Italy *CR The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index. 276
Wednesday – Posters – 4150 – 4169 4150 — A0068 Automated prediction of AMD progression from quantified SD-OCT images. Theodore Leng 1 , L. de Sisternes 2 , Q. Chen 2, 3 , J. Ma 1 , V. Mahendra 1 , D. Rubin 2 . 1 Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA; 2 Radiology and Medicine (Biomedical Informatics Research), Stanford University School of Medicine, Stanford, CA; 3 School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing, China *CR 4157 — A0075 The Dynamics of Hyperreflectant Central Target Lesions In Reticular Macular Disease (RMD) In Age-related Macular Degeneration (AMD). Nicole M. Pumariega 1 , R. M. Cymerman 1 , B. Butler 1 , N. Massamba 2 , E. H. Souied 2 , R. Smith 1 . 1 Ophthalmology, New York University Medical Center, College of Medicine, New York, NY; 2 Retina Creteil, Creteil Eye Clinic Univ Hospital, Créteil, France *CR 4163 — A0081 Dark Adaptometry As a Functional Outcome Measure in Age-Related Macular Degeneration. E Lauren Doss 1, 2 , T. Glaser 1, 2 , E. Agrón 2 , D. L. Nigam 2 , W. T. Wong 3 , E. Y. Chew 2 , C. A. Cukras 2 . 1 School of Medicine, University of California-San Francisco, San Francisco, CA; 2 National Eye Insititute, National Institutes of Health (NIH), Bethesda, MD; 3 Office of the Scientific Director, National Eye Institute, National Institutes of Health (NIH), Bethesda, MD 4164 — A0082 Diagnostic accuracy of multifocal pupillographic objective perimetry in early age-related macular degeneration. Faran Sabeti 1, 2 , A. Saikal 1, 2 , M. Kolic 1, 2 , C. F. Carle 1, 2 , R. W. Essex 3 , A. C. James 1, 2 , T. Maddess 1, 2 . 1 Eccles Institute of Neuroscience, Australian National University, Canberra, ACT, Australia; 2 ARC Centre of Excellence in Vision Science, Canberra, ACT, Australia; 3 Ophthalmology Department, The Canberra Hospital, Canberra, ACT, Australia *CR 4151 — A0069 Significance of Drusen Regression in Intermediate Age-Related Macular Degeneration (AMD) in Progression to Advanced Disease. Tanya Glaser 1, 2 , E. Doss 1, 2 , E. Agrón 1 , D. L. Nigam 1 , E. Y. Chew 1 , W. T. Wong 3 . 1 National Eye Institute, National Institutes of Health (NIH), Bethesda, MD; 2 School of Medicine, University of California - San Francisco, San Francisco, CA; 3 Office of the Scientific Director, National Eye Institute, National Institutes of Health (NIH), Bethesda, MD 4152 — A0070 The evaluation of fundus autofluorescence ( FAF) patterns in patient’s with Geographic Atrophy( GA) and the correlation with visual acuity. Ina K. Jaurre, S. Mudhar, N. Jain, M. Polyzos, G. Menon, L. North, M. N. Chandran. Eye treatment unit, Frimley Park Hospital, Frimley, Surrey, United Kingdom *CR 4153 — A0071 Investigation into the ability of Preferential Hyperacuity Perimetry (PHP) to detect reactivation of neovascularisation in patients undergoing ranibizumab injections for age-related macular degeneration (AMD). Stephanie Mroczkowska 1 , A. Calcagni 3, 1 , J. M. Gibson 1 , U. Chakravarthy 2 , R. E. Hogg 2 . 1 Ophthalmic Research Group, Aston University, Birmingham, United Kingdom; 2 Centre for Vision and Vascular Science, Queen’s University Belfast, Belfast, Ireland; 3 Birmingham and Midland Eye Centre, Birmingham, United Kingdom *CR 4154 — A0072 Automated Drusen Segmentation and Quantification from SD- OCT Images to Predict AMD Progression. Luis de Sisternes 1 , T. Leng 2 , Q. Chen 3 , J. Ma 2 , V. Mahendra 2 , D. Rubin 1 . 1 Radiology and Medicine, Stanford University School of Medicine, Stanford, CA; 2 Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, CA; 3 School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing, China *CR 4155 — A0073 Factors that predict the incidence of fellow eye in age-related macular degeneration. Kyung Min Koh, Y. Lew, M. Choi, S. Yoo, S. Cho, D. Lee, T. Lee, C. Kim, J. Han. Kim’s Eye Hospital, Seoul, Republic of Korea 4156 — A0074 Development of Choroidal Neovascularization in the Second Eye of Neovascular AMD Patients Treated with Anti- VEGF Drugs. Jonah Abraham, M. J. Elman. Elman Retina Group, PA, Baltimore, MD *CR 4158 — A0076 Relationship between reflectivity and volume of subretinal tissue in choroidal neovascular membranes associated with age-related macular degeneration. Wissam Charafeddin, S. Sadda, M. Nittala, M. S. Humayun, A. A. Oregon-Miranda. Doheny eye institute, Los angeles, CA *CR 4159 — A0077 Rod and Cone function and its relationship to OCT sub structural changes in Age-related Macular degeneration. Brighu Swamy 1 , E. N. Wong 3 , S. Degli Esposti 1 , P. A. Keane 2, 1 , M. D. Crossland 1 , D. A. Sim 1 , A. Tufail 1, 2 , F. K. Chen 3 . 1 Medical Retina, Moorfields Eye Hospital, London, United Kingdom; 2 UCL Institute of Ophthalmology National Institute for Health Research Biomedical Research Centre, London, United Kingdom; 3 Lions Eye Institute, Perth, WA, Australia *CR 4160 — A0078 OPERA (Optos Peripheral Retina AMD) Study Croatia: Reticular pigmentation in AMD vs. controls. Vesna Jurisic Friberg 1, 3 , B. Andrijevic Derk 2 , T. Knezevic 2 , M. Zoric-Geber 2 , G. Bencic 2 , Z. Vatavuk 2 , T. R. Friberg 4, 2 . 1 University Eye Clinic, Clinical Center, University of Sarajevo, Sarajevo, Bosnia and Herzegovina; 2 Ophthalmology, Kbc Sestre Milosrdnice and the University of Zagreb, Zagreb Croatia, Zagreb, Croatia; 3 Ophthalmology, Children’s Hospital-UPMC, Pittsburgh, PA; 4 Ophthalmology, UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA *CR 4161 — A0079 Morphological characteristics associated with drusen progression on Spectral Domain OCT (SD-OCT). Jeong W. Pak 1 , A. Domalpally 1 , D. Myers 1 , X. Yang 2 , A. R. Narkar 1 , Y. Huang 1 , R. P. Danis 1 . 1 Ophthalmology and Visual Science, University of Wisconsin - Madison, Madison, WI; 2 Beijing Tongren Eye Center, Capital Medical University, Beijing, China *CR 4162 — A0080 Clinical Outcomes of Eyes with Neovascular Lesions Composed of >50% Blood Treated with Anti-VEGF Therapy in the Comparison of AMD Treatments Trials (CATT). Michael M. Altaweel 1 , J. E. Grunwald 2 , E. Daniel 2 , G. Ying 2 , J. Huang 2 , G. J. Jaffe 3 . 1 Ophthalmology & Visual Science, Univ of Wisconsin-Madison, Madison, WI; 2 Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA; 3 Ophthalmology, Duke University, Durham, NC *CR, f 4165 — A0083 Imaging of Focal Hyperpigmentary Changes in Intermediate Agerelated Macular Degeneration - A Longitudinal Analysis. Arno P. Goebel, S. Grundei, M. Fleckenstein, F. G. Holz, S. Schmitz-Valckenberg. Department of Ophthalmology, University of Bonn, Bonn, Germany *CR 4166 — A0084 Reduction of the OCT second hyper-reflective band intensity is associated with a decreased in retinal function in eyes with agerelated macular degeneration. Chi D. Luu 1, 2 , Z. Wu 1, 2 , L. N. Ayton 1, 2 , R. H. Guymer 1, 2 . 1 Macular Research Unit, Centre for Eye Research Australia, East Melbourne, VIC, Australia; 2 Department of Ophthalmology, University of Melbourne, Parkville, VIC, Australia *CR 4167 — A0085 Progression of Reticular Macular Disease (RMD) in Age-Related Macular Degeneration (AMD). Rachel M. Cymerman 1 , N. M. Pumariega 1 , A. G. Sperber 1 , N. Massamba 2 , E. H. Souied 2 , R. Smith 1 . 1 New York University Medical Center, School of Medicine, New York, NY; 2 L’Hôpital Intercommunal de Créteil, Créteil, France *CR 4168 — A0086 Imaging of reticular drusen by multi-spectral confocal scanning laser ophthalmoscopy imaging. Jasmin Anke Ilka Auge, J. S. Steinberg, M. Fleckenstein, F. G. Holz, S. Schmitz-Valckenberg. University of Bonn, Bonn, Germany *CR 4169 — A0087 Reticular Pseudodrusen in Early Age-Related Macular Degeneration is Associated with Choroidal Thinning. Aakriti Garg 1 , M. Oll 1 , S. Yzer 1 , R. Allikmets 1, 2 , S. Chang 1 , G. R. Barile 3 , R. Smith 4 , J. C. Merriam 1 , S. H. Tsang 1, 2 , S. Bearelly 1 . 1 Ophthalmology, Columbia University College of Physicians and Surgeons, New York, NY; 2 Pathology & Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY; 3 Ophthalmology, Manhattan Eye, Ear, & Throat Hospital, New York, NY; 4 Ophthalmology, New York University Medical Center, New York, NY *CR Wednesday Posters 8:30 am – 10:15 am f Refer to the Program Number in the Clinical Trial (CT) Registration Index. *CR Refer to the Program Number in the Commercial Relationships (CR) Index for Disclosures. 277
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Wednesday - ARVO

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