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4083 – 4105 – <strong>Wednesday</strong> – Posters<br />
<strong>Wednesday</strong> Posters<br />
8:30 am – 10:15 am<br />
Exhibit Hall A0001-A0047<br />
<strong>Wednesday</strong>, May 08, 2013 8:30 AM-10:15 AM<br />
Retina<br />
413 AMD II, RE<br />
Moderators: David R. Hinton and Diana V. Do<br />
4083 — A0001 Pars Plana Vitrectomy,<br />
Subretinal Injection of Recombinant Tissue<br />
Plasminogen Activator and Intraocular Gas<br />
Tamponade for Thick Submacular Hemorrhage<br />
with Polypoidal Choroidal Vasculopathy.<br />
Woohyok Chang, C. Cho, M. Sagong, H. Oh, J.<br />
Park, D. Park, M. Kim, W. Gu, J. Son. Department<br />
of Ophthalmology, Yeungnam Univ College of<br />
Medicine, Daegu, Republic of Korea<br />
4084 — A0002 The Effects of Docosahexaenoic<br />
Acid (DHA) Dietary Supplementation on Retinal<br />
Lipid Profile in a Mouse Model of Stargardt-like<br />
Macular Dystrophy (STGD3). Mandy Hong 1 , S.<br />
Kuny 1 , R. Bryant 1 , F. Gaillard 1 , M. Suh 2 , Y. Sauve 1 .<br />
1<br />
Ophthalmology, University of Alberta, Edmonton,<br />
AB, Canada; 2 Human Nutritional Sciences,<br />
University of Manitoba, Winnipeg, MB, Canada<br />
4085 — A0003 In vivo Evaluation of Surface<br />
Modified Expanded-polytetrafluroethylene<br />
(ePTFE) Substrate as a Permanent Substrate<br />
for Cell Transplantation. Shen Nian 1 , Z. Fu 1 , C.<br />
M. Sheridan 3 , V. Kearns 3 , R. Williams 3 , S. Wong 1 ,<br />
K. Vasilev 4 , A. Bachhuka 4 , A. C. Lo 1, 2 , W. W. Lai 1 .<br />
1<br />
Ophthalmology, University of Hong Kong, Hong<br />
Kong, Hong Kong; 2 Research Centre of Heart,<br />
Brain, Hormone and Healthy Aging, University of<br />
Hong Kong, Hong Kong, Hong Kong; 3 Eye and<br />
Vision Science, University of Liverpool, Liverpool,<br />
United Kingdom; 4 Mawson Institute and School<br />
of Advanced Manufacturing, University of South<br />
Australia, Mawson Lakes, SA, Australia<br />
4086 — A0004 Prevalence of Subretinal<br />
Drusenoid Deposits in Age-Related Macular<br />
Degeneration with Newly Diagnosed Choroidal<br />
Neovascularization. Sandrine A. Zweifel, R. A.<br />
Rieder, M. M. Kohler, R. Gambon. Department of<br />
Ophthalmology, University Hospital Zurich, Zurich,<br />
Switzerland<br />
4087 — A0005 Autofluorescence and OCT of<br />
Retinal pigment epithelial tears. Naoto Hanyuda,<br />
T. Sato, R. Mukai, S. Kishi. Gunma University,<br />
Maebashi, Japan *CR<br />
4088 — A0006 Anatomic patterns and clinical<br />
presentation of recurrence in ‘stable’ wet Age<br />
Related Macular Degeneration (AMD) patients.<br />
Fani Zacharaki, M. N. Chandran, N. Nair, P.<br />
Vijayakumar, G. Menon. Frimley Park Hospital<br />
NHS Foundation Trust, Frimley, United Kingdom<br />
*CR<br />
4089 — A0007 Detection and Quantification<br />
of Autofluorescence Abnormalities in Patients<br />
with Neovascular Macular Degeneration using<br />
a Fully Automated Image Analysis Algorithm.<br />
Kathryn L. Pepple, Q. Nie, S. S. Ong, S. W. Cousins.<br />
Ophthalmology, Duke Eye Center, Durham, NC<br />
*CR<br />
4090 — A0008 Ranibizumab Leads to<br />
Regression or Elimination of Choroidal<br />
Neovascular Membranes in Most Eyes with<br />
AMD: A HARBOR Subanalysis. Nikolas J.<br />
London 1 , P. E. Tornambe 1 , L. Yau 2 , J. A. Nau 2 , L.<br />
Tuomi 2 . 1 Retina Consultants San Diego, San Diego,<br />
CA; 2 Genentech Inc., South San Francisco, CA<br />
*CR, f<br />
4091 — A0009 Anti-VEGF Gene Therapy for<br />
Wet AMD: Phase I/II Safety and Pharmacology<br />
Results. Elizabeth P. Rakoczy 1, 2 , M. Lai 1, 2 ,<br />
C. Pierce 2 , A. L. Magno 2 , R. Samulski 3 , T. W.<br />
Chalberg 4 , M. S. Blumenkranz 5 , I. Constable 1, 2 .<br />
1<br />
Centre for Ophthalmology and Visual Sciences,<br />
The University of Western Australia, Perth, WA,<br />
Australia; 2 Molecular Ophthalmology, Lions Eye<br />
Institute, Perth, WA, Australia; 3 Gene Therapy<br />
Centre, University of North Carolina, Chapel Hill,<br />
NC; 4 Avalanche Biotechnologies, San Francisco,<br />
CA; 5 Byers Eye Institute at Stanford, Palo Alto, CA<br />
*CR, f<br />
4092 — A0010 Polypoidal choroidal<br />
vasculopathy in Caucasian patients. Stephen<br />
Davis, A. Lauer, C. J. Flaxel. Oregon Health and<br />
Science University, Casey Eye Institute, Portland,<br />
OR *CR<br />
4093 — A0011 Baseline characteristics and<br />
response to intravitreal ranibizumab therapy for<br />
age-related macular degeneration. Misa Suzuki,<br />
N. Nagai, K. Izumi-Nagai, H. Shinoda, T. Koto,<br />
A. Uchida, H. Mochimaru, K. Yuki, K. Tsubota, Y.<br />
Ozawa. Ophthalmology, Keio University School of<br />
Medicine, Tokyo, Japan *CR, f<br />
4094 — A0012 Disease Activity in Disciform<br />
Scars due to Age-Related Macular Degeneration<br />
(AMD). Deborah Witkin 1 , J. B. Sanderson 1 , D.<br />
Ferrara 2, 1 , E. Reichel 1 . 1 Ophthalmology, Tufts<br />
Medical Center, Boston, MA; 2 Digital Angiography<br />
Reading Center DARC, Great Neck, NY *CR<br />
4095 — A0013 The Incidence of Neovascular<br />
Subtypes in Newly Diagnosed Wet Age-Related<br />
Macular Degeneration. Jesse J. Jung 1, 3 , L.<br />
Xu 2, 5 , R. Gallego-Pinazo 2, 4 , S. Mrejen 2, 3 , M.<br />
Marsiglia 2, 3 , S. Boddu 1 , K. Freund 1, 2 . 1 Department<br />
of Ophthalmology, New York Univ School of<br />
Med, New York, NY; 2 Vitreous Retina Macula<br />
Consultants of New York, New York, NY; 3 LuEsther<br />
T. Mertz Retinal Research Center, Manhattan<br />
Eye, Ear, and Throat Hospital, New York, NY;<br />
4<br />
Department of Ophthalmology, University and<br />
Polytechnic Hospital La Fe, Valencia, Spain; 5 St.<br />
Vincent’s Medical Center, Bridgeport, CT *CR<br />
4096 — A0014 Choroidal thickness change<br />
following intravitreal bevacizumab therapy<br />
for wet age-related macular degeneration: Six<br />
months results. Sharif Y. El Emam, G. Barteselli, J.<br />
Chhablani, S. Lee, I. Kozak, L. Cheng, W. Freeman.<br />
Ophthalmology, Shiley Eye Center, UCSD, La<br />
Jolla, CA *CR<br />
4097 — A0015 The Relationship of Choroidal<br />
Thickness to Scotopic Sensitivity in Agerelated<br />
Macular Degeneration (AMD). Karl G.<br />
Csaky 1, 3 , D. G. Birch 1, 2 , R. Gelman 1 , J. Felius 1 .<br />
1<br />
Ophthalmology, Retina Foundation of the<br />
Southwest, Dallas, TX; 2 Ophthalmology, University<br />
of Texas Southwestern Medical Center, Dallas, TX;<br />
3<br />
Texas Retina Associates, Dallas, TX *CR<br />
4098 — A0016 Choroidal Thickness<br />
following Anti-Vascular Endothelial Growth<br />
Factor Therapy for Neovascular Age-Related<br />
Macular Degeneration. Charlotte So, Z. Ravage.<br />
Ophthalmology, Rush University Medical Center,<br />
Chicago, IL<br />
4099 — A0017 Correlation Between Changes<br />
in Subfoveal Choroidal Thickness and 1-Year<br />
Outcomes of Ranibizumab Therapy for<br />
Polypoidal Choroidal Vasculopathy. Taiichi<br />
Hikichi, H. Kitamei, S. Shioya, M. Higuchi, T.<br />
Matsushita, S. Kosaka, R. Matsushita, K. Takami,<br />
H. Ohtsuka. Ohtsuka Eye Hospital, Sapporo, Japan<br />
4100 — A0018 Axial Length and Subfoveal<br />
Choroidal Thickness in Individuals with Agerelated<br />
Macular Degeneration (AMD). Chih<br />
Ping Wang 1, 2 , C. Lai 1, 2 , J. Huang 1, 2 , C. Kuo 1, 2 .<br />
1<br />
Department of Ophthalmology, Chang Gung<br />
Memorial Hospital, Chiayi, Chiayi County, Taiwan;<br />
2<br />
Chang Gung University, Taoyan, Taiwan<br />
4101 — A0019 APE1/Ref-1 redox inhibitor<br />
APX3330 modulates choroidal endothelial cells<br />
by transcriptional regulation of NF-κB and<br />
STAT3 activity. Xiaoxi Qiao 1 , Y. Li 1 , X. Liu 1 , T.<br />
Zhou 1 , M. R. Kelley 2 , P. A. Edwards 1 , H. Gao 1 .<br />
1<br />
Ophthalmology, Henry Ford Health System,<br />
Detroit, MI; 2 Herman B Wells Center for Pediatric<br />
Research, Indiana University School of Medicine,<br />
Indianapolis, IN *CR<br />
4102 — A0020 Apolipoprotein mimetic Dual<br />
Domain Peptide reduces Neutral Lipid Deposits<br />
in murine Bruch’s Membrane. Armin Mohi, S.<br />
Grisanti, M. Rudolf. Department of Ophthalmology,<br />
University of Luebeck, Luebeck, Germany *CR<br />
4103 — A0021 Identification of Human<br />
Macular Tissue Antigens Recognized by Serum<br />
Auto-Antibodies (auto-Abs) in Patients with<br />
Age-Related Macular Degeneration (AMD).<br />
Nataliya I. Lenchik 1, 2 , F. Giorgianni 3 , S. Beranova-<br />
Giorgianni 3 , I. C. Gerling 1 , M. Z. Radic 4 , A.<br />
Iannaccone 2 . 1 Medicine/Endocrinology, Univ.<br />
Tennessee HSC, Memphis, TN; 2 Hamilton Eye<br />
Institute, Univ. Tennessee HSC, Memphis, TN;<br />
3<br />
Pharmaceutical Sciences, Univ. Tennessee HSC,<br />
Memphis, TN; 4 Microbiology, Immunology &<br />
Biochemistry, Univ. Tennessee HSC, Memphis, TN<br />
4104 — A0022 Early ocular lipid deposition<br />
in a mouse model of hyperlipidemia and<br />
atherosclerosis. Michaela K. Mathews, T. Albukh,<br />
K. E. Duncan. Ophthalmology, Univ of Maryland,<br />
Baltimore, Baltimore, MD<br />
4105 — A0023 The role of systemic infection<br />
and response to Ranibizumab therapy for Age<br />
Related Macular Degeneration (AMD). Charles<br />
O. Pierce 1, 2 , M. Nelson 2 , J. Scott 1 , H. L. Griffiths 1 ,<br />
N. L. James 1 , H. A. Thomson 1 , A. J. Cree 1 , A. J.<br />
Lotery 1, 2 . 1 Clinical Neurosciences, University of<br />
Southampton, Southampton, United Kingdom;<br />
2<br />
University Hospital of Southampton, Southampton,<br />
United Kingdom *CR<br />
The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index.<br />
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