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4083 – 4105 – <strong>Wednesday</strong> – Posters<br />

<strong>Wednesday</strong> Posters<br />

8:30 am – 10:15 am<br />

Exhibit Hall A0001-A0047<br />

<strong>Wednesday</strong>, May 08, 2013 8:30 AM-10:15 AM<br />

Retina<br />

413 AMD II, RE<br />

Moderators: David R. Hinton and Diana V. Do<br />

4083 — A0001 Pars Plana Vitrectomy,<br />

Subretinal Injection of Recombinant Tissue<br />

Plasminogen Activator and Intraocular Gas<br />

Tamponade for Thick Submacular Hemorrhage<br />

with Polypoidal Choroidal Vasculopathy.<br />

Woohyok Chang, C. Cho, M. Sagong, H. Oh, J.<br />

Park, D. Park, M. Kim, W. Gu, J. Son. Department<br />

of Ophthalmology, Yeungnam Univ College of<br />

Medicine, Daegu, Republic of Korea<br />

4084 — A0002 The Effects of Docosahexaenoic<br />

Acid (DHA) Dietary Supplementation on Retinal<br />

Lipid Profile in a Mouse Model of Stargardt-like<br />

Macular Dystrophy (STGD3). Mandy Hong 1 , S.<br />

Kuny 1 , R. Bryant 1 , F. Gaillard 1 , M. Suh 2 , Y. Sauve 1 .<br />

1<br />

Ophthalmology, University of Alberta, Edmonton,<br />

AB, Canada; 2 Human Nutritional Sciences,<br />

University of Manitoba, Winnipeg, MB, Canada<br />

4085 — A0003 In vivo Evaluation of Surface<br />

Modified Expanded-polytetrafluroethylene<br />

(ePTFE) Substrate as a Permanent Substrate<br />

for Cell Transplantation. Shen Nian 1 , Z. Fu 1 , C.<br />

M. Sheridan 3 , V. Kearns 3 , R. Williams 3 , S. Wong 1 ,<br />

K. Vasilev 4 , A. Bachhuka 4 , A. C. Lo 1, 2 , W. W. Lai 1 .<br />

1<br />

Ophthalmology, University of Hong Kong, Hong<br />

Kong, Hong Kong; 2 Research Centre of Heart,<br />

Brain, Hormone and Healthy Aging, University of<br />

Hong Kong, Hong Kong, Hong Kong; 3 Eye and<br />

Vision Science, University of Liverpool, Liverpool,<br />

United Kingdom; 4 Mawson Institute and School<br />

of Advanced Manufacturing, University of South<br />

Australia, Mawson Lakes, SA, Australia<br />

4086 — A0004 Prevalence of Subretinal<br />

Drusenoid Deposits in Age-Related Macular<br />

Degeneration with Newly Diagnosed Choroidal<br />

Neovascularization. Sandrine A. Zweifel, R. A.<br />

Rieder, M. M. Kohler, R. Gambon. Department of<br />

Ophthalmology, University Hospital Zurich, Zurich,<br />

Switzerland<br />

4087 — A0005 Autofluorescence and OCT of<br />

Retinal pigment epithelial tears. Naoto Hanyuda,<br />

T. Sato, R. Mukai, S. Kishi. Gunma University,<br />

Maebashi, Japan *CR<br />

4088 — A0006 Anatomic patterns and clinical<br />

presentation of recurrence in ‘stable’ wet Age<br />

Related Macular Degeneration (AMD) patients.<br />

Fani Zacharaki, M. N. Chandran, N. Nair, P.<br />

Vijayakumar, G. Menon. Frimley Park Hospital<br />

NHS Foundation Trust, Frimley, United Kingdom<br />

*CR<br />

4089 — A0007 Detection and Quantification<br />

of Autofluorescence Abnormalities in Patients<br />

with Neovascular Macular Degeneration using<br />

a Fully Automated Image Analysis Algorithm.<br />

Kathryn L. Pepple, Q. Nie, S. S. Ong, S. W. Cousins.<br />

Ophthalmology, Duke Eye Center, Durham, NC<br />

*CR<br />

4090 — A0008 Ranibizumab Leads to<br />

Regression or Elimination of Choroidal<br />

Neovascular Membranes in Most Eyes with<br />

AMD: A HARBOR Subanalysis. Nikolas J.<br />

London 1 , P. E. Tornambe 1 , L. Yau 2 , J. A. Nau 2 , L.<br />

Tuomi 2 . 1 Retina Consultants San Diego, San Diego,<br />

CA; 2 Genentech Inc., South San Francisco, CA<br />

*CR, f<br />

4091 — A0009 Anti-VEGF Gene Therapy for<br />

Wet AMD: Phase I/II Safety and Pharmacology<br />

Results. Elizabeth P. Rakoczy 1, 2 , M. Lai 1, 2 ,<br />

C. Pierce 2 , A. L. Magno 2 , R. Samulski 3 , T. W.<br />

Chalberg 4 , M. S. Blumenkranz 5 , I. Constable 1, 2 .<br />

1<br />

Centre for Ophthalmology and Visual Sciences,<br />

The University of Western Australia, Perth, WA,<br />

Australia; 2 Molecular Ophthalmology, Lions Eye<br />

Institute, Perth, WA, Australia; 3 Gene Therapy<br />

Centre, University of North Carolina, Chapel Hill,<br />

NC; 4 Avalanche Biotechnologies, San Francisco,<br />

CA; 5 Byers Eye Institute at Stanford, Palo Alto, CA<br />

*CR, f<br />

4092 — A0010 Polypoidal choroidal<br />

vasculopathy in Caucasian patients. Stephen<br />

Davis, A. Lauer, C. J. Flaxel. Oregon Health and<br />

Science University, Casey Eye Institute, Portland,<br />

OR *CR<br />

4093 — A0011 Baseline characteristics and<br />

response to intravitreal ranibizumab therapy for<br />

age-related macular degeneration. Misa Suzuki,<br />

N. Nagai, K. Izumi-Nagai, H. Shinoda, T. Koto,<br />

A. Uchida, H. Mochimaru, K. Yuki, K. Tsubota, Y.<br />

Ozawa. Ophthalmology, Keio University School of<br />

Medicine, Tokyo, Japan *CR, f<br />

4094 — A0012 Disease Activity in Disciform<br />

Scars due to Age-Related Macular Degeneration<br />

(AMD). Deborah Witkin 1 , J. B. Sanderson 1 , D.<br />

Ferrara 2, 1 , E. Reichel 1 . 1 Ophthalmology, Tufts<br />

Medical Center, Boston, MA; 2 Digital Angiography<br />

Reading Center DARC, Great Neck, NY *CR<br />

4095 — A0013 The Incidence of Neovascular<br />

Subtypes in Newly Diagnosed Wet Age-Related<br />

Macular Degeneration. Jesse J. Jung 1, 3 , L.<br />

Xu 2, 5 , R. Gallego-Pinazo 2, 4 , S. Mrejen 2, 3 , M.<br />

Marsiglia 2, 3 , S. Boddu 1 , K. Freund 1, 2 . 1 Department<br />

of Ophthalmology, New York Univ School of<br />

Med, New York, NY; 2 Vitreous Retina Macula<br />

Consultants of New York, New York, NY; 3 LuEsther<br />

T. Mertz Retinal Research Center, Manhattan<br />

Eye, Ear, and Throat Hospital, New York, NY;<br />

4<br />

Department of Ophthalmology, University and<br />

Polytechnic Hospital La Fe, Valencia, Spain; 5 St.<br />

Vincent’s Medical Center, Bridgeport, CT *CR<br />

4096 — A0014 Choroidal thickness change<br />

following intravitreal bevacizumab therapy<br />

for wet age-related macular degeneration: Six<br />

months results. Sharif Y. El Emam, G. Barteselli, J.<br />

Chhablani, S. Lee, I. Kozak, L. Cheng, W. Freeman.<br />

Ophthalmology, Shiley Eye Center, UCSD, La<br />

Jolla, CA *CR<br />

4097 — A0015 The Relationship of Choroidal<br />

Thickness to Scotopic Sensitivity in Agerelated<br />

Macular Degeneration (AMD). Karl G.<br />

Csaky 1, 3 , D. G. Birch 1, 2 , R. Gelman 1 , J. Felius 1 .<br />

1<br />

Ophthalmology, Retina Foundation of the<br />

Southwest, Dallas, TX; 2 Ophthalmology, University<br />

of Texas Southwestern Medical Center, Dallas, TX;<br />

3<br />

Texas Retina Associates, Dallas, TX *CR<br />

4098 — A0016 Choroidal Thickness<br />

following Anti-Vascular Endothelial Growth<br />

Factor Therapy for Neovascular Age-Related<br />

Macular Degeneration. Charlotte So, Z. Ravage.<br />

Ophthalmology, Rush University Medical Center,<br />

Chicago, IL<br />

4099 — A0017 Correlation Between Changes<br />

in Subfoveal Choroidal Thickness and 1-Year<br />

Outcomes of Ranibizumab Therapy for<br />

Polypoidal Choroidal Vasculopathy. Taiichi<br />

Hikichi, H. Kitamei, S. Shioya, M. Higuchi, T.<br />

Matsushita, S. Kosaka, R. Matsushita, K. Takami,<br />

H. Ohtsuka. Ohtsuka Eye Hospital, Sapporo, Japan<br />

4100 — A0018 Axial Length and Subfoveal<br />

Choroidal Thickness in Individuals with Agerelated<br />

Macular Degeneration (AMD). Chih<br />

Ping Wang 1, 2 , C. Lai 1, 2 , J. Huang 1, 2 , C. Kuo 1, 2 .<br />

1<br />

Department of Ophthalmology, Chang Gung<br />

Memorial Hospital, Chiayi, Chiayi County, Taiwan;<br />

2<br />

Chang Gung University, Taoyan, Taiwan<br />

4101 — A0019 APE1/Ref-1 redox inhibitor<br />

APX3330 modulates choroidal endothelial cells<br />

by transcriptional regulation of NF-κB and<br />

STAT3 activity. Xiaoxi Qiao 1 , Y. Li 1 , X. Liu 1 , T.<br />

Zhou 1 , M. R. Kelley 2 , P. A. Edwards 1 , H. Gao 1 .<br />

1<br />

Ophthalmology, Henry Ford Health System,<br />

Detroit, MI; 2 Herman B Wells Center for Pediatric<br />

Research, Indiana University School of Medicine,<br />

Indianapolis, IN *CR<br />

4102 — A0020 Apolipoprotein mimetic Dual<br />

Domain Peptide reduces Neutral Lipid Deposits<br />

in murine Bruch’s Membrane. Armin Mohi, S.<br />

Grisanti, M. Rudolf. Department of Ophthalmology,<br />

University of Luebeck, Luebeck, Germany *CR<br />

4103 — A0021 Identification of Human<br />

Macular Tissue Antigens Recognized by Serum<br />

Auto-Antibodies (auto-Abs) in Patients with<br />

Age-Related Macular Degeneration (AMD).<br />

Nataliya I. Lenchik 1, 2 , F. Giorgianni 3 , S. Beranova-<br />

Giorgianni 3 , I. C. Gerling 1 , M. Z. Radic 4 , A.<br />

Iannaccone 2 . 1 Medicine/Endocrinology, Univ.<br />

Tennessee HSC, Memphis, TN; 2 Hamilton Eye<br />

Institute, Univ. Tennessee HSC, Memphis, TN;<br />

3<br />

Pharmaceutical Sciences, Univ. Tennessee HSC,<br />

Memphis, TN; 4 Microbiology, Immunology &<br />

Biochemistry, Univ. Tennessee HSC, Memphis, TN<br />

4104 — A0022 Early ocular lipid deposition<br />

in a mouse model of hyperlipidemia and<br />

atherosclerosis. Michaela K. Mathews, T. Albukh,<br />

K. E. Duncan. Ophthalmology, Univ of Maryland,<br />

Baltimore, Baltimore, MD<br />

4105 — A0023 The role of systemic infection<br />

and response to Ranibizumab therapy for Age<br />

Related Macular Degeneration (AMD). Charles<br />

O. Pierce 1, 2 , M. Nelson 2 , J. Scott 1 , H. L. Griffiths 1 ,<br />

N. L. James 1 , H. A. Thomson 1 , A. J. Cree 1 , A. J.<br />

Lotery 1, 2 . 1 Clinical Neurosciences, University of<br />

Southampton, Southampton, United Kingdom;<br />

2<br />

University Hospital of Southampton, Southampton,<br />

United Kingdom *CR<br />

The Commercial Relationships (CR) Index for Disclosures and the Clinical Trial (CT) Registration Index are at arvo.org/2013/ProgramSummary/Index.<br />

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