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Monte Carlo Techniques in radiation therapy - mcneg

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<strong>Monte</strong> <strong>Carlo</strong> <strong>Techniques</strong><br />

<strong>in</strong> <strong>radiation</strong> <strong>therapy</strong><br />

Henry Lawrence<br />

Ipswich Hospital


History of M/C<br />

<br />

Calculate π us<strong>in</strong>g method of Buffon and Laplace<br />

Throw a stick of length L onto a surface ruled with parallel<br />

l<strong>in</strong>es d apart.<br />

Buffon (1777) suggested that the probability of the stick cross<strong>in</strong>g the l<strong>in</strong>e<br />

p=2L/(π *d)<br />

Laplace (1886) suggested calculate π.<br />

Lawrence (2013) gave it a go, and got to<br />

~ 2 % after 3000 ‘throws’


Development of EGS/MCNP<br />

1949 von Neumann and Ulam<br />

1960 Etran and ITS<br />

1978 EGS3<br />

Step size artifacts <strong>in</strong> e- transport<br />

1985 EGS4<br />

PRESTA (Bielajew) solved step size problem<br />

2000 EGSnrc


Splitt<strong>in</strong>g<br />

Variance reduction<br />

– Uniform,dir. brems…<br />

Russian Roulette<br />

Range rejection<br />

Interaction forc<strong>in</strong>g


Dosimetry applications<br />

Stopp<strong>in</strong>g power ratios<br />

– Calculate fluence us<strong>in</strong>g m/c<br />

Detector response<br />

– Subtract components<br />

(4.4.1)<br />

– Position<strong>in</strong>g uncerta<strong>in</strong>ty<br />

(4.4.4)


Modell<strong>in</strong>g external photon beams<br />

1978 Patau<br />

– Target, flatten<strong>in</strong>g filter<br />

1981 Nilson and Brahme<br />

– Transparent components<br />

1988 Udale<br />

– Modular Philips l<strong>in</strong>ac<br />

1995 Rogers et al (BEAM)<br />

– General purpose code


Where do the photons come from?<br />

Chaney et al (1994)<br />

Centre of mass 6cm


Details of l<strong>in</strong>ac components<br />

Flatten<strong>in</strong>g filter<br />

– Different material


Multileaf collimator model<br />

Tongue and groove<br />

– [a] &[c] use ray trace<br />

– [c] <strong>in</strong>cludes t & g<br />

Intensity map<br />

M/C


kV cone beam CT<br />

Calibrat<strong>in</strong>g M/C calculated dose (D<strong>in</strong>g, 2008)<br />

– Wrt chamber <strong>in</strong> phantom ,then apply to image.


MatrixX<br />

– Chamber array<br />

– Limited resolution<br />

EPID<br />

– portal imager dose<br />

TPS<br />

– Analytical model<br />

IMRT verification


Tomo<strong>therapy</strong><br />

Rotat<strong>in</strong>g source<br />

Sterp<strong>in</strong>(2008)<br />

– TomoPen<br />

– PENELOPE code<br />

3 phase spaces<br />

– Each jaw sett<strong>in</strong>g<br />

Weight PSF<br />

– For each angle<br />

– Interpolate angles


Conclusion<br />

Excellent overview of M/C <strong>in</strong><br />

radio<strong>therapy</strong><br />

Helpful summary of computational<br />

issues<br />

Radiation physics concisely described


Thank you for your attention

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